Aged Gut Microbiota Contributes to Systemical Inflammaging after Transfer to Germ-Free Mice

Floris Fransen1,2, Adriaan A. van Beek3,2, Theo Borghuis1,2, Sahar El Aidy4, Floor Hugenholtz5,2, Christa E. van der Gaast‐de Jongh6, Huub F. J. Savelkoul3, Marien I. de Jonge6, Mark V. Boekschoten7,2, Hauke Smidt5,2, Marijke M. Faas8,1, Paul De Vos1,2
1Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands
2Top Institute Food and Nutrition, Wageningen, Netherlands
3Cell Biology and Immunology Group, Wageningen University, Wageningen, Netherlands
4Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, Netherlands
5Laboratory of Microbiology, Wageningen University, Wageningen, Netherlands
6Laboratory of Pediatric Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands
7Nutrition, Metabolism, and Genomics Group, Division of Human Nutrition, Wageningen University, Wageningen, Netherlands
8Department of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands

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