Mainstreaming cancer genetics: A model integrating germline BRCA testing into routine ovarian cancer clinics

Gynecologic Oncology - Tập 145 - Trang 130-136 - 2017
Maira Kentwell1,2, Eryn Dow1, Yoland Antill1, C. David Wrede2,3, Orla McNally2,3, Emily Higgs1, Anne Hamilton2,4,3, Sumitra Ananda2,4, Geoffrey J. Lindeman1,4,3,5, Clare L. Scott1,4,3,5
1Parkville Familial Cancer Centre, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Grattan Street, Parkville, Victoria 3050, Australia
2Gynaecology Oncology and Dysplasia Units, The Royal Women's Hospital, Flemington Road, Parkville, Victoria 3052, Australia
3The University of Melbourne, Melbourne, Victoria 3010, Australia
4Department of Medical Oncology, Peter MacCallum Cancer Centre, Grattan Street, Melbourne, Victoria 3050, Australia
5Stem Cells and Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Royal Parade, Parkville, Victoria 3052, Australia

Tài liệu tham khảo

Levine, 2016, Evolving approaches in research and care for ovarian cancers, a report from the national academies of sciences, engineering and medicine, JAMA, 315, 1943, 10.1001/jama.2016.2640 Alsop, 2012, BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group, J. Clin. Oncol., 30, 2654, 10.1200/JCO.2011.39.8545 Ledermann, 2012, Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer, N. Engl. J. Med., 366, 1382, 10.1056/NEJMoa1105535 Scott, 2015, Poly (ADP-ribose) polymerase inhibitors: recent advances and future development, J. Clin. Oncol., 33, 1397, 10.1200/JCO.2014.58.8848 Moore, 2014, SOLO1 and SOLO2: Randomised phase III trials of olaparib in patients (pts) with ovarian cancer and a BRCA1/2 mutation (BRCAm), J. Clin. Oncol., 32 Gonzalez-Martin, 2016, A randomised, double-blind phase III trial of naraparib maintenance treatment in patients with HRD+ advanced ovarian cancer after response to front-line platinum-based chemotherapy, J. Clin. Oncol., 34 Meiser, 2012, There is no decision to make: experiences and attitudes towards treatment-focused genetic testing among women diagnosed with ovarian cancer, Gynecol. Oncol., 124, 153, 10.1016/j.ygyno.2011.09.040 Ricci, 2015, Referral of ovarian cancer patients for genetic counselling by oncologists: need for improvement, Public Health Genomics, 18, 225, 10.1159/000431352 Cohen, 2016, Impact of clinical genetics attendance at a gynecologic oncology tumor board on referrals for genetic counseling and BRCA mutation testing, Int. J. Gynecol. Cancer, 26, 892, 10.1097/IGC.0000000000000689 Schwartz, 2014, Randomised non-inferiority trial of telephone versus in-person genetic counseling for hereditary breast and ovarian cancer, J. Clin. Oncol., 32, 618, 10.1200/JCO.2013.51.3226 George, 2016, Implementing rapid, robust, cost-effective, patient-centred, routine genetic testing in ovarian cancer patients, Sci. Rep., 13, 29506, 10.1038/srep29506 Percival, 2016, The integration of BRCA testing into oncology clinics, Br. J. Nurs., 25, 690, 10.12968/bjon.2016.25.12.690 Ledermann, 2016, Overall survival in patients with platinum-sensitive recurrent serous ovarian cancer receiving olaparib maintenance monotherapy: an updated analysis from a randomised, placebo-controlled, double-blind, phase 2 trial, Lancet Oncol., 17, 1579, 10.1016/S1470-2045(16)30376-X Swisher, 2016, Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial, Lancet Oncol. Douma, 2016, Non-genetic health professionals' attitude towards, knowledge of and skills in discussing and ordering genetic testing for hereditary cancer, Fam. Cancer, 15, 341, 10.1007/s10689-015-9852-6 Son, 2014, Completeness of pedigree and family cancer history for ovarian cancer patients, J. Gynecol. Oncol., 25, 342, 10.3802/jgo.2014.25.4.342 Rogers, 1984, The semi-structured genogram interview, Fam. Syst. Med., 2, 176, 10.1037/h0091655 Wilikins-Haug, 2000, Obstetrician-gynecologists' opinions and attitudes on the role of genetics in women's health, J. Womens Health Gend. Based Med., 9, 873, 10.1089/152460900750020900 Eccles, 2015, Understanding of BRCA VUS genetic results by breast cancer specialists, BMC Cancer, 15, 936, 10.1186/s12885-015-1934-1 Gleeson, 2013, Communication and information needs of women diagnosed with ovarian cancer regarding treatment-focused genetic testing, Oncol. Nurs. Forum, 40, 275, 10.1188/13.ONF.40-03AP Febbraro, 2015, Adherence patterns to National Comprehensive Cancer Network (NCCN) guidelines for referral to cancer genetic professionals, Gynecol. Oncol., 138, 109, 10.1016/j.ygyno.2015.04.029 Petzel, 2013, Genetic risk assessment for women with epithelial ovarian cancer: referral patterns and outcomes in a university gynecologic oncology clinic, J. Genet. Couns., 22, 662, 10.1007/s10897-013-9598-y