Organization and regulation of mitogen-activated protein kinase signaling pathways

Widmann, 1999, Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human, Phys Rev, 79, 143

Su, 1996, Mitogen-activated protein kinase cascades and regulation of gene expression, Curr Biol, 8, 402

Fanger, 1997, MEKKs, GCKs, MLKs, PAKs, TAKs, and Tpls: upstream regulators of the c-Jun amino-terminal kinases?, Curr Biol, 7, 67

Gutkind, 1998, The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades, J Biol Chem, 273, 1839, 10.1074/jbc.273.4.1839

Pawson, 1995, Protein modules and signalling networks, Nature, 373, 573, 10.1038/373573a0

Mochly-Rosen, 1995, Localization of protein kinases by anchoring protein: a theme in signal transduction, Science, 268, 247, 10.1126/science.7716516

Faux, 1996, Molecular glue: kinase anchoring and scaffold proteins, Cell, 85, 9, 10.1016/S0092-8674(00)81075-2

Faux, 1996, More on target with protein phosphorylation: conferring specificity by location, Trends Biochem Sci, 21, 312

Pawson, 1997, Signaling through scaffold, anchoring, and adapter proteins, Science, 278, 2075, 10.1126/science.278.5346.2075

Marcus, 1994, Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module, Proc Natl Acad Sci USA, 91, 7762, 10.1073/pnas.91.16.7762

Choi, 1994, Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae, Cell, 78, 499, 10.1016/0092-8674(94)90427-8

Printen, 1994, Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade, Genetics, 138, 609, 10.1093/genetics/138.3.609

Feng, 1998, Functional binding between Gβ and the LIM domain of Ste5 is required to activate the MEKK Ste11, Curr Biol, 8, 267, 10.1016/S0960-9822(98)70108-3

Herskowitz, 1995, MAP kinase pathways in yeast: for mating and more, Cell, 80, 187, 10.1016/0092-8674(95)90402-6

Wu, 1995, Molecular characterization of Ste20p, a potential mitogen-activated protein or extracellular signal-regulated kinase kinase (MEK) kinase kinase from Saccharomyces cerevisiae, J Biol Chem, 270, 15984, 10.1074/jbc.270.27.15984

Inouye, 1997, Ste5 RING-H2 domain: role in Ste4 promoted oligomerization for yeast pheromone signaling, Science, 278, 103, 10.1126/science.278.5335.103

Yablonski, 1996, Dimerization of Ste5, a mitogen-activated protein kinase cascade scaffold protein is required for signal transduction, Proc Natl Acad Sci USA, 93, 13864, 10.1073/pnas.93.24.13864

Posas, 1997, Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK, Science, 276, 1702, 10.1126/science.276.5319.1702

Schaeffer, 1998, MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade, Science, 281, 1668, 10.1126/science.281.5383.1668

Elion, 1998, Routing MAP kinase cascades, Science, 281, 1625, 10.1126/science.281.5383.1625

Bonny, 1998, IB1, a JIP-1 related nuclear protein present in insulin-secreting cells, J Biol Chem, 273, 1843, 10.1074/jbc.273.4.1843

Dickens, 1997, A cytoplasmic inhibitor of the JNK signal transduction pathway, Science, 277, 693, 10.1126/science.277.5326.693

Whitmarsh, 1998, A mammalian scaffold complex that selectively mediates MAP kinase activation, Science, 281, 1671, 10.1126/science.281.5383.1671

Schlesinger, 1998, The tao of MEKK, Frontiers in Bioscience, 3, 1182, 10.2741/A354

Yan, 1994, Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1, Nature, 372, 798, 10.1038/372798a0

Xu, 1997, MEKK1 binds directly to the c-Jun N-terminal kinases/stress-activated protein kinases, J Biol Chem, 272, 32056, 10.1074/jbc.272.51.32056

Su, 1997, NIK is a new Ste20 related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain, EMBO J, 16, 1279, 10.1093/emboj/16.6.1279

Hu, 1996, Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade, Gene Dev, 10, 2251, 10.1101/gad.10.18.2251

Therrien, 1995, KSR, a novel protein kinase required for RAS signal transduction, Cell, 83, 879, 10.1016/0092-8674(95)90204-X

Sundaram, 1995, The C. elegans Ksr-1 gene encodes a novel raf-related kinase involved in ras-mediated signal transduction, Cell, 83, 889, 10.1016/0092-8674(95)90205-8

Kornfeld, 1995, The Ksr-1 gene encodes a novel protein kinase involved in ras-mediated signaling in C. elegans, Cell, 83, 903, 10.1016/0092-8674(95)90206-6

Yu, 1997, Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK, Curr Biol, 8, 56, 10.1016/S0960-9822(98)70020-X

Freed, 1994, Binding of 14-3-3 proteins to the protein kinase Raf and effects of its activation, Science, 265, 1713, 10.1126/science.8085158

Irie, 1994, Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase, Science, 265, 1716, 10.1126/science.8085159

Fu, 1994, Interaction of the protein kinase Raf-1 with 14-3-3 proteins, Science, 266, 126, 10.1126/science.7939632

Li, 1995, Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins, EMBO J, 14, 685, 10.1002/j.1460-2075.1995.tb07047.x

Roberts, 1997, 14-3-3 proteins are essential for RAS/MAPK cascade signaling during pseudohyphal development in S. cerevisiae, Cell, 89, 1055, 10.1016/S0092-8674(00)80293-7

Yaffe, 1998, The structural basis for 14-3-3 phosphopeptide binding specificity, Cell, 91, 961, 10.1016/S0092-8674(00)80487-0

Tzivion, 1998, A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity, Nature, 394, 88, 10.1038/27938

Muslin, 1996, Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine, Cell, 84, 889, 10.1016/S0092-8674(00)81067-3

Clark, 1997, 14-3-3 ζ negatively regulates raf-1 activity by interactions with the raf-1 cysteine rich domain, J Biol Chem, 272, 20990, 10.1074/jbc.272.34.20990

Morrison, 1997, The, complexity of raf-1 regulation, Curr, Opin, Cell, Biol, 9, 174, 10.1016/S0955-0674(97)80060-9

Dent, 1995, Reversal of Raf-1 activation by purified and membrane-associated protein phosphatases, Science, 268, 1902, 10.1126/science.7604263

Fanger, 1998, 14-3-3 proteins interact with specific MEK kinases, J Biol Chem, 273, 3476, 10.1074/jbc.273.6.3476

Widmann, 1998, MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis, Mol Cell Biol, 18, 1, 10.1128/MCB.18.4.2416

Cardone, 1997, The regulation of anoikis: MEKK-1 activation requires cleavage by caspases, Cell, 90, 315, 10.1016/S0092-8674(00)80339-6

Sieburth, 1998, SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans, Cell, 94, 119, 10.1016/S0092-8674(00)81227-1

Therrien, 1998, CNK, a RAF-binding multidomain protein required for RAS signaling, Cell, 95, 343, 10.1016/S0092-8674(00)81766-3

Sternberg, 1998, Conspiracy, theory: Ras and Raf do not act alone, Cell, 95, 447, 10.1016/S0092-8674(00)81612-8

Tsunoda, 1997, A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade, Nature, 388, 243, 10.1038/40805

Rubin, 1994, A kinase anchor proteins and the intracellular targeting of signals carried by cyclic AMP, Biochim Biophys Acta, 1224, 467

Newton, 1996, Protein kinase C: ports of anchor in the cell, Curr Biol, 6, 806, 10.1016/S0960-9822(02)00600-0

Couet, 1997, Interaction of a receptor tyrosine kinase, EGR-R, with caveolins, J Biol Chem, 272, 30429, 10.1074/jbc.272.48.30429

Engelman, 1998, Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo, FEBS Lett, 428, 205, 10.1016/S0014-5793(98)00470-0

Fanger, 1997, MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42, EMBO J, 16, 4961, 10.1093/emboj/16.16.4961

Russell, 1995, Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1), J Biol Chem, 270, 11757, 10.1074/jbc.270.20.11757

Diener, 1997, Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase, Proc Natl Acad Sci USA, 94, 9687, 10.1073/pnas.94.18.9687

Pomerance, 1998, Grb2 interaction with MEK-kinase 1 is involved in regulation of Jun-kinase activities in response to epidermal growth factor, J Biol Chem, 273, 24301, 10.1074/jbc.273.38.24301