Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity

Cell Metabolism - Tập 31 - Trang 1173-1188.e5 - 2020
Vivian A. Paschoal1,2, Evelyn Walenta2, Saswata Talukdar2,3, Ariane R. Pessentheiner2, Olivia Osborn2, Nasun Hah4, Tyler J. Chi2, George L. Tye2,5, Aaron M. Armando6, Ronald M. Evans4,7, Nai-Wen Chi2,8, Oswald Quehenberger6, Jerrold M. Olefsky2, Da Young Oh1,2
1Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
2Division of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA
3Merck & Co., Inc., SSF, 630 Gateway Boulevard, South San Francisco, CA 94080, USA
4Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
5Case Western Reserve University School of Medicine, 2109 Adelbert Road, Cleveland, OH 44106, USA
6Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA
7Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
8VA San Diego Healthcare System, San Diego, CA, USA

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