Endocytosis of nanomedicines

Journal of Controlled Release - Tập 145 - Trang 182-195 - 2010
Gaurav Sahay1, Daria Y. Alakhova1, Alexander V. Kabanov1,2,3
1Department of Pharmaceutical Sciences and Center for Drug Delivery and Nanomedicine, College of Pharmacy, M.V. Lomonosov Moscow State University, 119899 Moscow, Russia
2Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198-5830, M.V. Lomonosov Moscow State University, 119899 Moscow, Russia
3Faculty of Chemistry, M.V. Lomonosov Moscow State University, 119899 Moscow, Russia

Tài liệu tham khảo

Kabanov, 2002, Pluronic (R) block copolymers in drug delivery: from micellar nanocontainers to biological response modifiers, Critical Reviews in Therapeutic Drug Carrier Systems, 19, 1, 10.1615/CritRevTherDrugCarrierSyst.v19.i1.10 Duncan, 2003, The dawning era of polymer therapeutics, Nature Review Drug Discovery, 2, 347, 10.1038/nrd1088 Farokhzad, 2006, Nanomedicine: developing smarter therapeutic and diagnostic modalities, Advanced Drug Delivery Reviews, 58, 1456, 10.1016/j.addr.2006.09.011 Davis, 2008, Nanoparticle therapeutics: an emerging treatment modality for cancer, Nature Review Drug Discovery, 7, 771, 10.1038/nrd2614 Peer, 2007, Nanocarriers as an emerging platform for cancer therapy, Nature Nanotechnology, 2, 751, 10.1038/nnano.2007.387 Tasciotti, 2008, Mesoporous silicon particles as a multistage delivery system for imaging and therapeutic applications, Nature Nanotechnology, 3, 151, 10.1038/nnano.2008.34 Rajendran, 2010, Subcellular targeting strategies for drug design and delivery, Nature Review Drug Discovery, 9, 29, 10.1038/nrd2897 Germain, 2004, An innately interesting decade of research in immunology, Nature Medicine, 10, 1307, 10.1038/nm1159 Conner, 2003, Regulated portals of entry into the cell, Nature, 422, 37, 10.1038/nature01451 Mayor, 2007, Pathways of clathrin-independent endocytosis, Nature Review Molecular Cell Biology, 8, 603, 10.1038/nrm2216 Wieffer, 2009, SnapShot: endocytic trafficking, Cell, 137, 382.e381, 10.1016/j.cell.2009.04.012 Doherty, 2009, Mechanisms of endocytosis, Annual Review of Biochemistry, 78, 857, 10.1146/annurev.biochem.78.081307.110540 Zerial, 2001, Rab proteins as membrane organizers, Nature Review Molecular Cell Biology, 2, 107, 10.1038/35052055 Glebov, 2006, Flotillin-1 defines a clathrin-independent endocytic pathway in mammalian cells, Nature Cell Biology, 8, 46, 10.1038/ncb1342 Storrie, 1998, Recycling of Golgi-resident glycosyltransferases through the ER reveals a novel pathway and provides an explanation for nocodazole-induced Golgi scattering, Journal of Cell Biology, 143, 1505, 10.1083/jcb.143.6.1505 Falcon-Perez, 2005, Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3, Journal of Cell Science, 118, 5243, 10.1242/jcs.02633 Fliegel, 1989, Molecular cloning of the high affinity calcium-binding protein (calreticulin) of skeletal muscle sarcoplasmic reticulum, Journal of Biological Chemistry, 264, 21522, 10.1016/S0021-9258(20)88216-7 Hanson, 2004, Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators, Journal of Biological Chemistry, 279, 13044, 10.1074/jbc.M312846200 Kabouridis, 1997, S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes, The European Molecular Biology Organization Journal, 16, 4983, 10.1093/emboj/16.16.4983 Straight, 1997, Mitosis in living budding yeast: anaphase a but no metaphase plate, Science, 277, 574, 10.1126/science.277.5325.574 Sahay, 2009, The utilization of pathogen-like cellular trafficking by single chain block copolymer, Biomaterials Oh, 2007, Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung, Nature Biotechnology, 25, 327, 10.1038/nbt1292 Vasir, 2008, Quantification of the force of nanoparticle-cell membrane interactions and its influence on intracellular trafficking of nanoparticles, Biomaterials, 29, 4244, 10.1016/j.biomaterials.2008.07.020 Mercer, 2009, Virus entry by macropinocytosis, Nature Cell Biology, 11, 510, 10.1038/ncb0509-510 A.I. Ivanov, Pharmacological Inhibition of Endocytic Pathways: Is It Specific Enough to Be Useful?, Methods in Molecular Biology 2008, Review. Sahay, 2010, The exploitation of differential endocytic pathways in normal and tumor cells in the selective targeting of nanoparticulate chemotherapeutic agents, Biomaterials, 31, 923, 10.1016/j.biomaterials.2009.09.101 Tuli, 2009, Mechanism for amyloid precursor-like protein 2 enhancement of major histocompatibility complex class I molecule degradation, Journal of Biological Chemistry, 284, 34296, 10.1074/jbc.M109.039727 Damm, 2005, Clathrin- and caveolin-1-independent endocytosis: entry of simian virus 40 into cells devoid of caveolae, Journal of Cell Biology, 168, 477, 10.1083/jcb.200407113 Gumbleton, 2005, Coming out of the dark: the evolving role of fluorescence imaging in drug delivery research, Advanced Drug Delivery Reviews, 57, 5, 10.1016/j.addr.2004.08.002 Lai, 2008, Real-time multiple particle tracking of gene nanocarriers in complex biological environments, Methods in Molecular Biology, 434, 81, 10.1007/978-1-60327-248-3_6 Hillaireau, 2009, Nanocarriers' entry into the cell: relevance to drug delivery, Cellular and Molecular Life Sciences, 66, 2873, 10.1007/s00018-009-0053-z Aderem, 1999, Mechanisms of phagocytosis in macrophages, Annual Review of Immunology, 17, 593, 10.1146/annurev.immunol.17.1.593 Rabinovitch, 1995, Professional and nonprofessional phagocytes-an introduction, Trends in Cell Biology, 5, 85, 10.1016/S0962-8924(00)88955-2 Cannon, 1992, The macrophage capacity for phagocytosis, Journal of Cell Sciences, 101, 907, 10.1242/jcs.101.4.907 Champion, 2007, Making polymeric micro- and nanoparticles of complex shapes, Proceedings of the National Academy of Sciences, 104, 11901, 10.1073/pnas.0705326104 Champion, 2006, Role of target geometry in phagocytosis, Proceedings of the National Academy of Sciences, 103, 4930, 10.1073/pnas.0600997103 Pucadyil, 2009, Conserved functions of membrane active GTPases in coated vesicle formation, Science, 325, 1217, 10.1126/science.1171004 Slepnev, 2000, Accessory factors in clathrin-dependent synaptic vesicle endocytosis, Nature Review Neuroscience, 1, 161, 10.1038/35044540 Ford, 2002, Curvature of clathrin-coated pits driven by epsin, Nature, 419, 361, 10.1038/nature01020 Rappoport, 2008, Focusing on clathrin-mediated endocytosis, Biochemical Journal, 412, 415, 10.1042/BJ20080474 Harush-Frenkel, 2007, Targeting of nanoparticles to the clathrin-mediated endocytic pathway, Biochemical and Biophysical Research Communications, 353, 26, 10.1016/j.bbrc.2006.11.135 Harush-Frenkel, 2008, Surface charge of nanoparticles determines their endocytic and transcytotic pathway in polarized MDCK cells, Biomacromolecules, 9, 435, 10.1021/bm700535p Lahtinen, 2003, Involvement of caveolin-2 in caveolar biogenesis in MDCK cells, Federation of the Societies of Biochemistry and Molecular Biology Letters, 538, 85 Vogel, 1998, Expression of caveolin-1 and polarized formation of invaginated caveolae in Caco-2 and MDCK II cells, Journal of Cell Science, 111, 825, 10.1242/jcs.111.6.825 Lü, 2009, Current advances in research and clinical applications of PLGA-based nanotechnology, Expert Review of Molecular Diagnostics, 9, 325, 10.1586/erm.09.15 Panyam, 2003, Dynamics of endocytosis and exocytosis of Poly(d, l-lactide-co-Glycolide) nanoparticles in vascular smooth muscle cells, Pharmaceutical Research, 20, 212, 10.1023/A:1022219003551 Qaddoumi, 2004, The characteristics and mechanisms of uptake of PLGA nanoparticles in rabbit conjunctival epithelial cell layers, Pharmaceutical Research, 21, 641, 10.1023/B:PHAM.0000022411.47059.76 Nan, 2008, Cellular uptake and cytotoxicity of silica nanotubes, Nano Letters, 8, 2150, 10.1021/nl0802741 Chung, 2007, The effect of surface charge on the uptake and biological function of mesoporous silica nanoparticles in 3T3-L1 cells and human mesenchymal stem cells, Biomaterials, 28, 2959, 10.1016/j.biomaterials.2007.03.006 Ma, 2003, Uptake of chitosan and associated insulin in caco-2 cell monolayers: a comparison between chitosan molecules and chitosan nanoparticles, Pharmaceutical Research, 20, 1812, 10.1023/B:PHAM.0000003379.76417.3e Huang, 2002, Uptake of FITC-chitosan nanoparticles by A549 cells, Pharmaceutical Research, 19, 1488, 10.1023/A:1020404615898 Nam, 2009, Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles, Journal of Controlled Release, 135, 259, 10.1016/j.jconrel.2009.01.018 Bareford, 2007, Endocytic mechanisms for targeted drug delivery, Advanced Drug Delivery Reviews, 59, 748, 10.1016/j.addr.2007.06.008 Tekle, 2008, Cellular trafficking of quantum dot-ligand bioconjugates and their induction of changes in normal routing of unconjugated ligands, Nano Letters, 8, 1858, 10.1021/nl0803848 Sahay, 2008, Different internalization pathways of polymeric micelles and unimers and their effects on vesicular transport, Bioconjugate Chemistry, 19, 2023, 10.1021/bc8002315 Simons, 2000, Lipid rafts and signal transduction, Nature Review Molecular Cell Biology, 1, 31, 10.1038/35036052 Nabi, 2009, Cavin fever: regulating caveolae, Nature Cell Biology, 11, 789, 10.1038/ncb0709-789 Schnitzer, 1995, Endothelial caveolae have the molecular transport machinery for vesicle budding, docking, and fusion including VAMP, NSF, SNAP, annexins, and GTPases, Journal of Biological Chemistry, 270, 14399, 10.1074/jbc.270.24.14399 Parton, 2007, The multiple faces of caveolae, Nature Review Molecular Cell Biology, 8, 185, 10.1038/nrm2122 Carver, 2003, Caveolae: mining little caves for new cancer targets, Nature Review Cancer, 3, 571, 10.1038/nrc1146 Rejman, 2006, Gene transfer by means of lipo- and polyplexes: role of clathrin and caveolae-mediated endocytosis, Journal of Liposome Research, 16, 237, 10.1080/08982100600848819 Garcia-Cardena, 1996, Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling, Proceedings of National Academy of Science U S A, 93, 6448, 10.1073/pnas.93.13.6448 Bronich, 2005, Polymer micelle with cross-linked ionic core, Journal of the American Chemical Society, 127, 8236, 10.1021/ja043042m Nishikawa, 2009, Nitric oxide release in human aortic endothelial cells mediated by delivery of amphiphilic polysiloxane nanoparticles to caveolae, Biomacromolecules, 10, 2074, 10.1021/bm900128x Zhang, 2009, Mechanisms of quantum dot nanoparticle cellular uptake, Toxicological Sciences, 110, 138, 10.1093/toxsci/kfp087 Moreno-Aspitia, 2005, Nanoparticle albumin-bound paclitaxel (ABI-007): a newer taxane alternative in breast cancer, Future Oncology, 1, 755, 10.2217/14796694.1.6.755 Gradishar, 2006, Albumin-bound paclitaxel: a next-generation taxane, Expert Opinion on Pharmacotherapy, 7, 1041, 10.1517/14656566.7.8.1041 Schnitzer, 1992, gp60 is an albumin-binding glycoprotein expressed by continuous endothelium involved in albumin transcytosis, American Journal of Physiology, Heart and Circulatory Physiology, 262, H246, 10.1152/ajpheart.1992.262.1.H246 Desai, 2008, Improved effectiveness of nanoparticle albumin-bound (nab) paclitaxel versus polysorbate-based docetaxel in multiple xenografts as a function of HER2 and SPARC status, Anti-Cancer Drugs, 19, 899, 10.1097/CAD.0b013e32830f9046 Gradishar, 2006, Albumin-bound paclitaxel: a next-generation taxane, Expert Opinion on Pharmacotherapy, 7, 1041, 10.1517/14656566.7.8.1041 Oba, 2008, Polyplex micelles with cyclic rgd peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular trafficking, Molecular Pharmaceutics, 5, 1080, 10.1021/mp800070s Larson, 2005, Temporally resolved interactions between antigen-stimulated IgE receptors and Lyn kinase on living cells, Journal of Cell Biology, 171, 527, 10.1083/jcb.200503110 Sabharanjak, 2002, GPI-anchored proteins are delivered to recycling endosomes via a distinct cdc42-regulated, clathrin-independent pinocytic pathway, Developmental Cell, 2, 411, 10.1016/S1534-5807(02)00145-4 Tuli, 2008, Amyloid precursor-like protein 2 increases the endocytosis, instability, and turnover of the H2-Kd MHC class i molecule, Journal of Immunology, 181, 1978, 10.4049/jimmunol.181.3.1978 Lu, 2002, Folate-mediated delivery of macromolecular anticancer therapeutic agents, Advanced Drug Delivery Reviews, 54, 675, 10.1016/S0169-409X(02)00042-X Rijnboutt, 1996, Endocytosis of GPI-linked membrane folate receptor-alpha, Journal of Cell Biology, 132, 35, 10.1083/jcb.132.1.35 Kerr, 2009, Defining macropinocytosis, Traffic, 10, 364, 10.1111/j.1600-0854.2009.00878.x Jones, 2007, Macropinocytosis: searching for an endocytic identity and role in the uptake of cell penetrating peptides, Journal of Cellular and Molecular Medicine, 11, 670, 10.1111/j.1582-4934.2007.00062.x Swanson, 2008, Shaping cups into phagosomes and macropinosomes, Nature Review Molecular Cell Biology, 9, 639, 10.1038/nrm2447 Gratton, 2008, The pursuit of a scalable nanofabrication platform for use in material and life science applications, Accounts of Chemical Research, 41, 1685, 10.1021/ar8000348 Gratton, 2008, The effect of particle design on cellular internalization pathways, Proceedings of the National Academy of Sciences, 105, 11613, 10.1073/pnas.0801763105 Batrakova, 2008, Pluronic block copolymers: evolution of drug delivery concept from inert nanocarriers to biological response modifiers, Journal of Controlled Release, 130, 98, 10.1016/j.jconrel.2008.04.013 Lai, 2008, Characterization of the intracellular dynamics of a non-degradative pathway accessed by polymer nanoparticles, Journal of Controlled Release, 125, 107, 10.1016/j.jconrel.2007.10.015 Esfand, 2001, Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications, Drug Discovery Today, 6, 427, 10.1016/S1359-6446(01)01757-3 Kitchens, 2007, Endocytosis and interaction of Poly (Amidoamine) dendrimers with Caco-2 cells, Pharmaceutical Research, 24, 2138, 10.1007/s11095-007-9415-0 Seib, 2007, Comparison of the endocytic properties of linear and branched PEIs, and cationic PAMAM dendrimers in B16f10 melanoma cells, Journal of Controlled Release, 117, 291, 10.1016/j.jconrel.2006.10.020 Kitchens, 2008, Endocytosis inhibitors prevent Poly(amidoamine) dendrimer internalization and permeability across Caco-2 cells, Molecular Pharmaceutics, 5, 364, 10.1021/mp700089s Kitchens, 2006, Transport of Poly(Amidoamine) dendrimers across Caco-2 cell monolayers: influence of size, Charge and Fluorescent Labeling, Pharmaceutical Research, 23, 2818, 10.1007/s11095-006-9122-2 Kabanov, 1995, DNA complexes with polycations for the delivery of genetic material into cells, Bioconjugate Chemistry, 6, 7, 10.1021/bc00031a002 von Gersdorff, 2006, The internalization route resulting in successful gene expression depends on both cell line and polyethylenimine polyplex type, Molecular Therapy, 14, 745, 10.1016/j.ymthe.2006.07.006 Akinc, 2005, Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis, The Journal of Gene Medicine, 7, 657, 10.1002/jgm.696 Rejman, 2005, Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes, Molecular Therapy, 12, 468, 10.1016/j.ymthe.2005.03.038 Yang, 2008, Amphiphilic block copolymers enhance cellular uptake and nuclear entry of polyplex-delivered DNA, Bioconjugate Chemistry, 19, 1987, 10.1021/bc800144a Lühmann, 2008, Cellular uptake and intracellular pathways of PLL-g-PEG-DNA nanoparticles, Bioconjugate Chemistry, 19, 1907, 10.1021/bc800206r Wong, 2007, DNA internalized via caveolae requires microtubule-dependent, Rab7-independent transport to the late endocytic pathway for delivery to the nucleus, Journal of Biological Chemistry, 282, 22953, 10.1074/jbc.M611015200 Bausinger, 2006, The transport of nanosized gene carriers unraveled by live-cell imaging13, Angewandte Chemie International Edition, 45, 1568, 10.1002/anie.200503021 Suh, 2003, Efficient active transport of gene nanocarriers to the cell nucleus, Proceedings of the National Academy of Sciences of the United States of America, 100, 3878, 10.1073/pnas.0636277100 Boussif, 1995, A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine, Proceedings of the National Academy of Sciences, 92, 7297, 10.1073/pnas.92.16.7297 Miller, 2009, Tissue-specific and transcription factor-mediated nuclear entry of DNA, Advanced Drug Delivery Reviews, 61, 603, 10.1016/j.addr.2009.02.008 Sriadibhatla, 2006, Transcriptional activation of gene expression by pluronic block copolymers in stably and transiently transfected cells, Molecular Therapy, 13, 804, 10.1016/j.ymthe.2005.07.701 Gaymalov, 2009, The effect of the nonionic block copolymer pluronic P85 on gene expression in mouse muscle and antigen-presenting cells, Biomaterials, 30, 1232, 10.1016/j.biomaterials.2008.10.064 Fumoto, 2009, Rac-mediated macropinocytosis is a critical route for naked plasmid DNA transfer in mice, Molecular Pharmaceutics, 6, 1170, 10.1021/mp900042p Wadia, 2005, Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer, Advanced Drug Delivery Reviews, 57, 579, 10.1016/j.addr.2004.10.005 Torchilin, 2008, Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers, Advanced Drug Delivery Reviews, 60, 548, 10.1016/j.addr.2007.10.008 Kaplan, 2005, Cationic TAT peptide transduction domain enters cells by macropinocytosis, Journal of Controlled Release, 102, 247, 10.1016/j.jconrel.2004.10.018 Wadia, 2004, Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis, Nature Medicine, 10, 310, 10.1038/nm996 Patel, 2007, Cell penetrating peptides: intracellular pathways and pharmaceutical perspectives, Pharmaceutical Research, 24, 1977, 10.1007/s11095-007-9303-7 Sawant, 2006, “SMART” drug delivery systems: double-targeted pH-responsive pharmaceutical nanocarriers, Bioconjugate Chemistry, 17, 943, 10.1021/bc060080h Kumar, 2007, Transvascular delivery of small interfering RNA to the central nervous system, Nature, 448, 39, 10.1038/nature05901 Liu, 2009, Brain-targeting gene delivery and cellular internalization mechanisms for modified rabies virus glycoprotein RVG29 nanoparticles, Biomaterials, 30, 4195, 10.1016/j.biomaterials.2009.02.051 Liu, 2009, Biorecognition and subcellular trafficking of hpma copolymer — anti-PSMA antibody conjugates by prostate cancer cells, Molecular Pharmaceutics, 6, 959, 10.1021/mp8002682 Muro, 2008, Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers, Molecular Therapy, 16, 1450, 10.1038/mt.2008.127 Champion, 2009, Shape induced inhibition of phagocytosis of polymer particles, Pharmaceutical Research, 26, 244, 10.1007/s11095-008-9626-z Kabanov, 2009, Nanogels as pharmaceutical carriers: finite networks of infinite capabilities, Angewandte Chemie International Edition, 48, 5418, 10.1002/anie.200900441 Basu, 2009, Nanoparticle-mediated targeting of MAPK signaling predisposes tumor to chemotherapy, Proceedings of the National Academy of Sciences, 106, 7957, 10.1073/pnas.0902857106 D.Y. Alakhova, N.Y. Rapoport, E.V. Batrakova, A.A. Timoshin, S. Li, D. Nicholls, V.Y. Alakhov, A.V. Kabanov, Differential metabolic responses to pluronic in MDR and non-MDR cells: A novel pathway for chemosensitization of drug resistant cancers, Journal of Controlled Release, In Press, Corrected Proof. M. Capitani, M. Sallese, The KDEL receptor: New functions for an old protein, Federation of the Societies of Biochemistry and Molecular Biology Letters, In Press, Corrected Proof. Sabharanjak, 2004, Folate receptor endocytosis and trafficking, Advanced Drug Delivery Reviews, 56, 1099, 10.1016/j.addr.2004.01.010 Arima, 2008, Complement activation on surfaces modified with ethylene glycol units, Biomaterials, 29, 551, 10.1016/j.biomaterials.2007.10.015