SUMO
Tóm tắt
Từ khóa
Tài liệu tham khảo
al-Khodairy, 1995, The Schizosaccharomyces pombe hus5 gene encodes a ubiquitin conjugating enzyme required for normal mitosis, J. Cell Sci., 108, 475, 10.1242/jcs.108.2.475
Andrews, 2005, Nse2, a component of the Smc5–6 complex, is a SUMO ligase required for the response to DNA damage, Mol. Cell. Biol., 25, 185, 10.1128/MCB.25.1.185-196.2005
Azuma, 2003, SUMO-2/3 regulates topoisomerase II in mitosis, J. Cell Biol., 163, 477, 10.1083/jcb.200304088
Bachant, 2002, The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II, Mol. Cell, 9, 1169, 10.1016/S1097-2765(02)00543-9
Bernier-Villamor, 2002, Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1, Cell, 108, 345, 10.1016/S0092-8674(02)00630-X
Betz, 2001, A Drosophila PIAS homologue negatively regulates stat92E, Proc. Natl. Acad. Sci. USA, 98, 9563, 10.1073/pnas.171302098
Boggio, 2004, A mechanism for inhibiting the SUMO pathway, Mol. Cell, 16, 549, 10.1016/j.molcel.2004.11.007
Bohren, 2004, A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus, J. Biol. Chem., 279, 27233, 10.1074/jbc.M402273200
Bylebyl, 2003, The SUMO isopeptidase Ulp2 prevents accumulation of SUMO chains in yeast, J. Biol. Chem., 278, 44113, 10.1074/jbc.M308357200
Callewaert, 2004, Differential effect of small ubiquitin-like modifier (SUMO)-ylation of the androgen receptor in the control of cooperativity on selective versus canonical response elements, Mol. Endocrinol., 18, 1438, 10.1210/me.2003-0313
Choi, 1999, The homeodomain protein NK-3 recruits Groucho and a histone deacetylase complex to repress transcription, J. Biol. Chem., 274, 33194, 10.1074/jbc.274.47.33194
Desterro, 1998, SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation, Mol. Cell, 2, 233, 10.1016/S1097-2765(00)80133-1
Desterro, 1999, Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1, J. Biol. Chem., 274, 10618, 10.1074/jbc.274.15.10618
Desterro, 1997, Ubch9 conjugates SUMO but not ubiquitin, FEBS Lett., 417, 297, 10.1016/S0014-5793(97)01305-7
Dieckhoff, 2004, Smt3/SUMO and Ubc9 are required for efficient APC/C-mediated proteolysis in budding yeast, Mol. Microbiol., 51, 1375, 10.1046/j.1365-2958.2003.03910.x
Duprez, 1999, SUMO-1 modification of the acute promyelocytic leukaemia protein PML: implications for nuclear localisation, J. Cell Sci., 112, 381, 10.1242/jcs.112.3.381
Everett, 2000, ICP0, a regulator of herpes simplex virus during lytic and latent infection, Bioessays, 22, 761, 10.1002/1521-1878(200008)22:8<761::AID-BIES10>3.0.CO;2-A
Fischle, 2003, Binary switches and modification cassettes in histone biology and beyond, Nature, 425, 475, 10.1038/nature02017
Fraser, 2000, Functional genomic analysis of C. elegans chromosome I by systematic RNA interference, Nature, 408, 325, 10.1038/35042517
Gan-Erdene, 2003, Identification and characterization of DEN1, a deneddylase of the ULP family, J. Biol. Chem., 278, 28892, 10.1074/jbc.M302890200
Gill, 2004, SUMO and ubiquitin in the nucleus: different functions, similar mechanisms?, Genes Dev., 18, 2046, 10.1101/gad.1214604
Girdwood, 2003, p300 transcriptional repression is mediated by SUMO modification, Mol. Cell, 18, 1043, 10.1016/S1097-2765(03)00141-2
Gong, 1999, Molecular cloning and characterization of human AOS1 and UBA2, components of the sentrin-activating enzyme complex, FEBS Lett., 448, 185, 10.1016/S0014-5793(99)00367-1
Goodson, 2001, Sumo-1 modification regulates the DNA binding activity of heat shock transcription factor 2, a promyelocytic leukemia nuclear body associated transcription factor, J. Biol. Chem., 276, 18513, 10.1074/jbc.M008066200
Gostissa, 1999, Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1, EMBO J., 18, 6462, 10.1093/emboj/18.22.6462
Haracska, 2004, Opposing effects of ubiquitin conjugation and SUMO modification of PCNA on replicational bypass of DNA lesions in Saccharomyces cerevisiae, Mol. Cell. Biol., 24, 4267, 10.1128/MCB.24.10.4267-4274.2004
Hardeland, 2002, Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover, EMBO J., 21, 1456, 10.1093/emboj/21.6.1456
Hari, 2001, The Drosophila Su(var)2–10 locus regulates chromosome structure and function and encodes a member of the PIAS protein family, Genes Dev., 15, 1334, 10.1101/gad.877901
Hayashi, 2002, Ubc9 is essential for viability of higher eukaryotic cells, Exp. Cell Res., 280, 212, 10.1006/excr.2002.5634
Hochstrasser, 2001, SP-RING for SUMO: new functions bloom for a ubiquitin-like protein, Cell, 107, 5, 10.1016/S0092-8674(01)00519-0
Hoege, 2002, RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO, Nature, 419, 135, 10.1038/nature00991
Holmstrom, 2003, Direct and distinguishable inhibitory roles for SUMO isoforms in the control of transcriptional synergy, Proc. Natl. Acad. Sci. USA, 100, 15758, 10.1073/pnas.2136933100
Hong, 2001, Regulation of heat shock transcription factor 1 by stress-induced SUMO-1 modification, J. Biol. Chem., 276, 40263, 10.1074/jbc.M104714200
Huang, 2003, Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress, Cell, 115, 565, 10.1016/S0092-8674(03)00895-X
Iniguez-Lluhi, 2000, A common motif within the negative regulatory regions of multiple factors inhibits their transcriptional synergy, Mol. Cell. Biol., 20, 6040, 10.1128/MCB.20.16.6040-6050.2000
Ishov, 1999, PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1, J. Cell Biol., 147, 221, 10.1083/jcb.147.2.221
Johnson, 2004, Protein modification by SUMO, Annu. Rev. Biochem., 73, 355, 10.1146/annurev.biochem.73.011303.074118
Johnson, 1997, Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p, J. Biol. Chem., 272, 26799, 10.1074/jbc.272.43.26799
Johnson, 2001, An E3-like Factor that Promotes SUMO Conjugation to the Yeast Septins, Cell, 106, 735, 10.1016/S0092-8674(01)00491-3
Johnson, 1997, The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer, EMBO J., 16, 5509, 10.1093/emboj/16.18.5509
Joseph, 2002, SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles, J. Cell Biol., 156, 595, 10.1083/jcb.200110109
Kagey, 2004, Multiple activities contribute to Pc2 E3 function, EMBO J., 24, 108, 10.1038/sj.emboj.7600506
Kamitani, 1998, Identification of three major sentrinization sites in PML, J. Biol. Chem., 273, 26675, 10.1074/jbc.273.41.26675
Kim, 1999, Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1, Proc. Natl. Acad. Sci. USA, 96, 12350, 10.1073/pnas.96.22.12350
Kirsh, 2002, The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase, EMBO J., 21, 2682, 10.1093/emboj/21.11.2682
Kurepa, 2003, The small ubiquitin-like modifier (SUMO) protein modification system in Arabidopsis. Accumulation of SUMO1 and -2 conjugates is increased by stress, J. Biol. Chem., 278, 6862, 10.1074/jbc.M209694200
Kwek, 2001, Functional analysis and intracellular localization of p53 modified by SUMO-1, Oncogene, 20, 2587, 10.1038/sj.onc.1204362
Lallemand-Breitenbach, 2001, Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation, J. Exp. Med., 193, 1361, 10.1084/jem.193.12.1361
Lehembre, 2001, Regulation of Pax3 transcriptional activity by SUMO-1-modified PML, Oncogene, 20, 1, 10.1038/sj.onc.1204063
Lehming, 1998, Chromatin components as part of a putative transcriptional repressing complex, Proc. Natl. Acad. Sci. USA, 95, 7322, 10.1073/pnas.95.13.7322
Li, 2000, Sequestration and inhibition of Daxx-mediated transcriptional repression by PML, Mol. Cell. Biol., 20, 1784, 10.1128/MCB.20.5.1784-1796.2000
Li, 1999, A new protease required for cell-cycle progression in yeast, Nature, 398, 246, 10.1038/18457
Li, 2000, The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein, Mol. Cell. Biol., 20, 2367, 10.1128/MCB.20.7.2367-2377.2000
Li, 2004, SUMOylation of heterogeneous nuclear ribonucleoproteins, zinc finger proteins, and nuclear pore complex proteins: A proteomic analysis, Proc. Natl. Acad. Sci. USA, 101, 8551, 10.1073/pnas.0402889101
Liang, 2004, Regulation of Smad4 SUMOylation and transforming growth factor-beta signaling by protein inhibitor of activated STAT1, J. Biol. Chem., 279, 22857, 10.1074/jbc.M401554200
Lin, 2002, Identification of a substrate recognition site on ubc9, J. Biol. Chem., 277, 21740, 10.1074/jbc.M108418200
Lin, 2003, Activation of transforming growth factor-beta signaling by SUMO-1 modification of tumor suppressor Smad4/DPC4, J. Biol. Chem., 278, 18714, 10.1074/jbc.M302243200
Lin, 2003, Opposed Regulation of Corepressor CtBP by SUMOylation and PDZ Binding, Mol. Cell, 11, 1389, 10.1016/S1097-2765(03)00175-8
Liu, 2004, PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity, Nat. Immunol., 5, 891, 10.1038/ni1104
Long, 2004, Repression of Smad4 transcriptional activity by SUMO modification, Biochem. J., 379, 23, 10.1042/bj20031867
Maeda, 2004, Ubc9 is required for damage-tolerance and damage-induced interchromosomal homologous recombination in S. cerevisiae, DNA Repair, 3, 335, 10.1016/j.dnarep.2003.11.011
Mahajan, 1997, A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2, Cell, 88, 97, 10.1016/S0092-8674(00)81862-0
Matunis, 1996, A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex, J. Cell Biol., 135, 1457, 10.1083/jcb.135.6.1457
Melchior, 2003, SUMO: ligases, isopeptidases and nuclear pores, Trends Biochem. Sci., 28, 612, 10.1016/j.tibs.2003.09.002
Meluh, 1995, Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C, Mol. Biol. Cell, 6, 793, 10.1091/mbc.6.7.793
Mendoza, 2003, NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins, J. Biol. Chem., 278, 25637, 10.1074/jbc.M212948200
Mossessova, 2000, Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast, Mol. Cell, 5, 865, 10.1016/S1097-2765(00)80326-3
Muller, 1999, Viral immediate-early proteins abrogate the modification by SUMO-1 of PML and Sp100 proteins, correlating with nuclear body disruption, J. Virol., 73, 5137, 10.1128/JVI.73.6.5137-5143.1999
Muller, 1998, Trivalent antimonials induce degradation of the PML-RAR oncoprotein and reorganization of the promyelocytic leukemia nuclear bodies in acute promyelocytic leukemia NB4 cells, Blood, 92, 4308, 10.1182/blood.V92.11.4308
Muller, 2000, c-Jun and p53 activity is modulated by SUMO-1 modification, J. Biol. Chem., 275, 13321, 10.1074/jbc.275.18.13321
Ohshima, 2003, TGF-b mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription through SUMO-1 modification of Smad4, J. Biol. Chem., 278, 50833, 10.1074/jbc.M307533200
Okuma, 1999, In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2, Biochem. Biophys. Res. Commun., 254, 693, 10.1006/bbrc.1998.9995
Pichler, 2002, The nucleoporin RanBP2 has SUMO1 E3 ligase activity, Cell, 108, 109, 10.1016/S0092-8674(01)00633-X
Pichler, 2004, The RanBP2 SUMO E3 ligase is neither HECT- nor RING-type, Nat. Struct. Mol. Biol., 11, 984, 10.1038/nsmb834
Poukka, 2000, Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1), Proc. Natl. Acad. Sci. USA, 97, 14145, 10.1073/pnas.97.26.14145
Rodriguez, 1999, SUMO-1 modification activates the transcriptional response of p53, EMBO J., 18, 6455, 10.1093/emboj/18.22.6455
Rodriguez, 2001, SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting, J. Biol. Chem., 276, 12654, 10.1074/jbc.M009476200
Ross, 2002, SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization, Mol. Cell, 10, 831, 10.1016/S1097-2765(02)00682-2
Roth, 2004, PIASy-deficient mice display modest defects in IFN and Wnt signaling, J. Immunol., 173, 6189, 10.4049/jimmunol.173.10.6189
Saitoh, 2000, Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3, J. Biol. Chem., 275, 6252, 10.1074/jbc.275.9.6252
Saitoh, 2002, Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358, J. Biol. Chem., 277, 4755, 10.1074/jbc.M104453200
Sampson, 2001, The small ubiquitin-like modifier-1 (SUMO-1) consensus sequence mediates Ubc9 binding and is essential for SUMO-1 modification, J. Biol. Chem., 276, 21664, 10.1074/jbc.M100006200
Sapetschnig, 2002, Transcription factor Sp3 is silenced through SUMO modification by PIAS1, EMBO J., 21, 5206, 10.1093/emboj/cdf510
Seeler, 1998, Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment, Proc. Natl. Acad. Sci. USA, 95, 7316, 10.1073/pnas.95.13.7316
Seeler, 2001, Common properties of nuclear body protein SP100 and TIF1alpha chromatin factor: role of SUMO modification, Mol. Cell. Biol., 21, 3314, 10.1128/MCB.21.10.3314-3324.2001
Seufert, 1995, Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins, Nature, 373, 78, 10.1038/373078a0
Sharma, 2003, hZimp10 is an androgen receptor co-activator and forms a complex with SUMO-1 at replication foci, EMBO J., 22, 6101, 10.1093/emboj/cdg585
Shayeghi, 1997, Characterisation of Schizosaccharomyces pombe rad31, a UBA-related gene required for DNA damage tolerance, Nucleic Acids Res., 25, 1162, 10.1093/nar/25.6.1162
Shiio, 2003, Histone SUMOylation is associated with transcriptional repression, Proc. Natl. Acad. Sci. USA, 100, 13225, 10.1073/pnas.1735528100
Snowden, 2000, A novel transcriptional repression domain mediates p21(WAF1/CIP1) induction of p300 transactivation, Mol. Cell. Biol., 20, 2676, 10.1128/MCB.20.8.2676-2686.2000
Sobko, 2002, Regulated SUMOylation and ubiquitination of DdMEK1 is required for proper chemotaxis, Dev. Cell, 2, 745, 10.1016/S1534-5807(02)00186-7
Stade, 2002, A Lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast, J. Biol. Chem., 277, 49554, 10.1074/jbc.M207991200
Stead, 2003, Pds5p regulates the maintenance of sister chromatid cohesion and is sumoylated to promote the dissolution of cohesion, J. Cell Biol., 163, 729, 10.1083/jcb.200305080
Steffan, 2004, SUMO modification of Huntingtin and Huntington’s disease pathology, Science, 304, 100, 10.1126/science.1092194
Stelter, 2003, Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation, Nature, 425, 188, 10.1038/nature01965
Su, 2002, Molecular features of human ubiquitin-like SUMO genes and their encoded proteins, Gene, 296, 65, 10.1016/S0378-1119(02)00843-0
Takahashi, 2000, Yeast Ulp1, an Smt3-specific protease, associates with nucleoporins, J. Biochem. (Tokyo), 128, 723, 10.1093/oxfordjournals.jbchem.a022807
Takahashi, 2001, Yeast Ull1/Siz1 is a novel SUMO1/Smt3 ligase for septin components and functions as an adaptor between conjugating enzyme and substrates, J. Biol. Chem., 276, 48973, 10.1074/jbc.M109295200
Tanaka, 1999, Characterization of a fission yeast SUMO-1 homologue, pmt3p, required for multiple nuclear events, including the control of telomere length and chromosome segregation, Mol. Cell. Biol., 19, 8660, 10.1128/MCB.19.12.8660
Tatham, 2003, Role of two residues proximal to the active site of Ubc9 in substrate recognition by the Ubc9.SUMO-1 thiolester complex, Biochemistry, 42, 3168, 10.1021/bi026861x
Tatham, 2001, Polymeric chains of sumo-2 and sumo-3 are conjugated to protein substrates by sae1/sae2 and ubc9, J. Biol. Chem., 276, 35368, 10.1074/jbc.M104214200
Tatham, 2004, Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection, Nat. Struct. Mol. Biol., 12, 67, 10.1038/nsmb878
Taylor, 2002, Cell-cycle-dependent localisation of Ulp1, a Schizosaccharomyces pombe Pmt3 (SUMO)-specific protease, J. Cell Sci., 115, 1113, 10.1242/jcs.115.6.1113
Terui, 2004, Dual role of SUMOylation in the nuclear localization and transcriptional activation of NFAT1, J. Biol. Chem., 279, 28257, 10.1074/jbc.M403153200
Vassileva, 2004, SUMO modification of heterogeneous nuclear ribonucleoproteins, Mol. Cell. Biol., 24, 3623, 10.1128/MCB.24.9.3623-3632.2004
Vertegaal, 2004, A proteomic study of SUMO-2 target proteins, J. Biol. Chem., 279, 33791, 10.1074/jbc.M404201200
Wong, 2004, Protein inhibitor of activated STAT Y (PIASy) and a splice variant lacking exon 6 enhance SUMOylation but are not essential for embryogenesis and adult life, Mol. Cell. Biol., 24, 5577, 10.1128/MCB.24.12.5577-5586.2004
Wu, 2003, DEN1 is a dual function protease capable of processing the C-terminus of Nedd8 deconjugating hyper-neddylated CUL1, J. Biol. Chem., 278, 28882, 10.1074/jbc.M302888200
Yang, 2004, SUMO promotes HDAC-mediated transcriptional repression, Mol. Cell, 13, 611, 10.1016/S1097-2765(04)00060-7
Yang, 2003, Dynamic interplay of the SUMO and ERK pathways in regulating Elk-1 transcriptional activity, Mol. Cell, 16, 611
Yeh, 2000, Ubiquitin-like proteins: new wines in new bottles, Gene, 248, 1, 10.1016/S0378-1119(00)00139-6
Zhang, 2002, Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex, Mol. Cell. Biol., 22, 6498, 10.1128/MCB.22.18.6498-6508.2002
Zhang, 2004, SUMO modification is required for in vivo Hox gene regulation by the Caenorhabditis elegans Polycomb group protein SOP-2, Nat. Genet., 36, 507, 10.1038/ng1336
Zhao, 2004, Broad spectrum identification of cellular small ubiquitin-related modifier (SUMO) substrate proteins, J. Biol. Chem., 279, 20999, 10.1074/jbc.M401541200