Vascular biology of atherosclerosis: overview and state of the art

Libby, 2002, Inflammation and atherosclerosis, Circulation, 105, 1135, 10.1161/hc0902.104353

Poole, 1958, Changes in the endothelium of the aorta and the behavior of macrophages in experimental atheroma of rabbits, J Pathol Bacteriol, 75, 245, 10.1002/path.1700750202

Li, 1993, An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium, Arterioscler Thromb, 13, 197, 10.1161/01.ATV.13.2.197

Cybulsky, 2001, A major role for VCAM-1, but not ICAM-1, in early atherosclerosis, J Clin Invest, 107, 1255, 10.1172/JCI11871

Gu, 1998, Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice, Mol Cell, 2, 275, 10.1016/S1097-2765(00)80139-2

Boring, 1998, Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis, Nature, 394, 894, 10.1038/29788

Mach, 1999, Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells, J Clin Invest, 104, 1041, 10.1172/JCI6993

Qiao, 1997, Role of macrophage colony-stimulating factor in atherosclerosis, Am J Pathol, 150, 1687

Rosenfeld, 1992, Macrophage colony-stimulating factor mRNA and protein in atherosclerotic lesions of rabbits and humans, Am J Pathol, 140, 291

Clinton, 1992, Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis, Am J Pathol, 140, 301

Rajavashisth, 1998, Heterozygous osteopetrotic (op) mutation reduces atherosclerosis in LDL receptor-deficient mice, J Clin Invest, 101, 2702, 10.1172/JCI119891

Smith, 1995, Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E, Proc Natl Acad Sci U S A, 92, 8264, 10.1073/pnas.92.18.8264

Ross, 1999, Atherosclerosis, N Engl J Med, 340, 115, 10.1056/NEJM199901143400207

Howard, 1999, Chemokines as molecular targets for therapeutic intervention, J Clin Immunol, 19, 280, 10.1023/A:1020587407535

Kotowicz, 2000, Biological function of CD40 on human endothelial cells, Immunology, 100, 441, 10.1046/j.1365-2567.2000.00061.x

Mach, 1997, Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages, Proc Natl Acad Sci U S A, 94, 1931, 10.1073/pnas.94.5.1931

Mach, 1997, Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40, Circulation, 96, 396, 10.1161/01.CIR.96.2.396

Schonbeck, 1997, Ligation of CD40 activates interleukin 1beta-converting enzyme (caspase-1) activity in vascular smooth muscle and endothelial cells and promotes elaboration of active interleukin 1beta, J Biol Chem, 272, 19569, 10.1074/jbc.272.31.19569

Mach, 1999, T lymphocytes induce endothelial cell matrix metalloproteinase expression by a CD40L-dependent mechanism, Am J Pathol, 154, 229, 10.1016/S0002-9440(10)65269-8

Mach, 1998, Reduction of atherosclerosis in mice by inhibition of CD40 signalling, Nature, 394, 200, 10.1038/28204

Schonbeck, 2000, Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice, Proc Natl Acad Sci U S A, 97, 7458, 10.1073/pnas.97.13.7458

Lutgens, 2000, Both early and delayed anti-CD40L antibody treatment induces a stable plaque phenotype, Proc Natl Acad Sci U S A, 97, 7464, 10.1073/pnas.97.13.7464

Lutgens, 2002, CD40-CD40L interactions in atherosclerosis, Trends Cardiovasc Med, 12, 27, 10.1016/S1050-1738(01)00142-6

Garlichs, 2001, Up regulation of CD40 and CD40 ligand (CD154) in patients with moderate hypercholesterolemia, Circulation, 104, 2395, 10.1161/hc4501.099312

Schonbeck, 2001, Soluble CD40L and cardiovascular risk in women, Circulation, 104, 2266, 10.1161/hc4401.099447

Gerdes, 2002, Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages, J Exp Med, 195, 245, 10.1084/jem.20011022