On the local cardiac renin angiotensin system. Basic and clinical implications

Ahn, 2004, Cardiac structural and functional responses to salt loading in SHR, Am J Physiol (Heart Circ Physiol), 287, H767, 10.1152/ajpheart.00047.2004 Bader, 2002, Role of the local renin–angiotensin system in cardiac damage: a minireview focussing on transgenic animal models, J Mol Cell Cardiol, 34, 1455, 10.1006/jmcc.2002.2077 Clausmeyer, 1999, An alternative transcript of the rat renin gene can result in a truncated prorenin that is transported into adrenal mitochondria, Cir Res, 84, 337, 10.1161/01.RES.84.3.337 Cook, 2006, Lessons from experimental generation of intracellular angiotensinogen and angiotensin II, 73 Cook, 2006, Re RN nuclear accumulation of the AT1 receptor in a rat vascular smooth muscle cell line: effects upon signal transduction and cellular proliferation, J Mol Cell Cardiol, 40, 696, 10.1016/j.yjmcc.2005.11.014 Cook, 2007, Long term effects of dietary sodium reduction on cardiovascular disease outcomes: observational follow-up of the trials of hypertension prevention (TOHP), BMJ, 334, 885, 10.1136/bmj.39147.604896.55 Costerousse, 1997, Genetics of angiotensin I-converting enzyme, Clin Exp Hypertens, 19, 659, 10.3109/10641969709083177 Danser, 1994, Cardiac renin and angiotensins; uptake from plasma versus in situ synthesis, Hypertension, 24, 37, 10.1161/01.HYP.24.1.37 De Mello, 1994, Is an intracellular renin angiotensin system involved in the control of cell communication in heart?, J Cardiovasc Pharmacol, 23, 640, 10.1097/00005344-199404000-00018 De Mello, 1998, Intracellular angiotensin II regulates the inward calcium current in cardiac myocytes, Hypertension, 32, 076, 10.1161/01.HYP.32.6.976 De Mello, 2000, Angiotensin II and the heart. On the intracrine renin angiotensin system, Hypertension, 35, 1183, 10.1161/01.HYP.35.6.1183 De Mello, 2004, Heart failure: how important is cellular sequestration? The role of the renin angiotensin aldosterone system, J Mol Cell Cardiol, 37, 431, 10.1016/j.yjmcc.2004.05.007 De Mello, 2009, Systemic versus local renin angiotensin systems. An overview, 1 De Mello, 2008, Eplerenone inhibits the intracellular and extracellular actions of angiotensin II on the inward calcium current in the failing heart. On the presence of an intracrine renin angiotensin aldosterone system, Reg Pept, 151, 54, 10.1016/j.regpep.2008.06.003 De Mello, 2001, Cardiac arrhythmias: the possible role of the renin angiotensin system, J Mol Med, 79, 103, 10.1007/s001090100195 De Mello, 2006, On the pathophysiological implications of an intracellular renin receptor, Circ Res, 99, 1285, 10.1161/01.RES.0000253141.65450.fc De Mello, 2003, Further studies on the effect of intracellular angiotensins on heart cell communication: on the role of endogenous angiotensin II, Reg Pept, 115, 31, 10.1016/S0167-0115(03)00128-9 De Mello, 2011, Novel aspects of angiotensin II action in the heart. Implications to myocardial ischemia and heart failure, Regul Pept, 166, 9, 10.1016/j.regpep.2010.10.003 Diez, 2010, A translational approach to hypertensive heart disease, Hypertension, 55, 1, 10.1161/HYPERTENSIONAHA.109.141887 Domenighetti, 2005, Angiotensin II-mediated phenotypic cardiomyocyte remodeling leads to age-dependent cardiac dysfunction and failure, Hypertension, 46, 426, 10.1161/01.HYP.0000173069.53699.d9 Frohlich, 1992, The heart in hypertension, N Engl J Med, 3227, 998, 10.1056/NEJM199210013271406 Frohlich, 1999, Risk mechanisms in hypertensive heart disease, Hypertension, 34, 782, 10.1161/01.HYP.34.4.782 Frohlich, 2011, Hypertensive left ventricular hypertrophy risk: beyond adaptive cardiomyocytic hypertrophy, J Hypertens, 20, 17, 10.1097/HJH.0b013e328340d787 Frohlich, 2009, Clinical import of the local renin angiotensin aldosterone system, 6 Frohlich, 2007, The salt conundrum: a hypothesis, Hypertension, 50, 161, 10.1161/HYPERTENSIONAHA.107.088328 Frohlich, 1993, Relationships between dietary sodium intake, hemodynamics and cardiac mass in spontaneously hypertensive and normotensive Wistar–Kyoto rats, Am J Physiol, 234, R30 Hein, 1997, Overexpression of angiotensin AT1 receptor in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block, Proc Natl Acad Sci USA, 94, 6391, 10.1073/pnas.94.12.6391 Hein, 1997, Intracellular trafficking of angiotensin II and its AT1 and AT2 receptors: evidence for selective sorting of receptor and ligand, Mol Endocrinol, 11, 1266, 10.1210/mend.11.9.9975 Jafar, 2001, Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease. A meta-analysis of patient-level data, Ann Intern Med, 135, 73, 10.7326/0003-4819-135-2-200107170-00007 Kantachuverisi, 2001, Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease, J Biol Chem, 276, 36727, 10.1074/jbc.M103296200 Kumar, 2008, The intracellular renin angiotensin system: implications in cardiovascular remodeling, Curr Opin Nephrol Hypertens, 17, 168, 10.1097/MNH.0b013e3282f521a8 Kurdi, 2005, Working outside the system: an uptodate on unconventional behavior of the renin angiotensin system components, Int J Biochem Cell Biol, 37, 1357, 10.1016/j.biocel.2005.01.012 Malhotra, 1999, Mechanical stretch and angiotensin II differentially upregulated the renin angiotensin system in cardiac myocytes in vitro, Circ Res, 85, 137, 10.1161/01.RES.85.2.137 Mazzolai, 1998, Blood pressure-independent cardiac hypertrophy induced by locally activated renin angiotensin system, Hypertension, 31, 1324, 10.1161/01.HYP.31.6.1324 Matavelli, 2007, Salt-loading produces severe renal hemodynamic dysfunction independent of arterial pressure in spontaneously hypertensive rats, Am J Physiol Heart Circ Physiol, 292, H814, 10.1152/ajpheart.00671.2006 Nguyen, 2002, Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular response to renin, J Clin Invest, 109, 1417, 10.1172/JCI0214276 Nguyen, 2008, Prorenin and (pro)renin receptor: a review of available data from in vitro studies and experimental models in rodents, Exp Physiol, 93, 557, 10.1113/expphysiol.2007.040030 Nishiyama, 2004, Effect of AT1 receptor blockade on renal injury and mitogen-activated protein activity in Dahl salt-sensitive rats, Kidney Int, 65, 972, 10.1111/j.1523-1755.2004.00476.x Palomeque, 2009, Angiotensin II-induced oxidative stress resets the Ca2+ dependence of Ca2+-calmodulin protein kinase II and promotes a death pathway conserved across different species, Circ Res, 105, 1204, 10.1161/CIRCRESAHA.109.204172 Passier, 1996, Expression and localization of renin and angiotensinogen in rat heart after myocardial infarction, Am J Physiol, 271, H1040 Pfeffer, 2006, Improvements in clinical outcomes with the use of angiotensin-converting enzyme inhibitors: cross-fertilization between clinical and basic investigation, Am J Physiol Heart Circ Physiol, 291, H2021, 10.1152/ajpheart.00647.2006 Pfeffer, 1985, Influence of chronic captopril therapy on the infracted left ventricle of the rat, Circ Res, 57, 84, 10.1161/01.RES.57.1.84 Re, 2003, The implication of intracrine hormone action for physiology and medicine, Am J Physiol Heart Circ Physiol, 284, H751, 10.1152/ajpheart.00935.2002 Re, 2008, The basis of an intracrine physiology, J Clin Pharmacol, 48, 344, 10.1177/0091270007312155 Reudelhuber, 2007, Is angiotensin II a direct mediator of left ventricular hypertrophy?, Hypertension, 49, 1196, 10.1161/HYPERTENSIONAHA.106.075085 Saris, 2001, Cardomyocytes bind and activate native human prorenin: role of soluble mannose-6 phosphate receptors, Hypertension, 37, 710, 10.1161/01.HYP.37.2.710 Serneri, 2001, Cardiac angiotensin II formation in the clinical course of heart failure and its relationship with left ventricular function, Circ Res, 88, 961, 10.1161/hh0901.089882 Shefe, 2006, A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein, Circ Res, 99, 1355, 10.1161/01.RES.0000251700.00994.0d Singh, 2008, Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis, Diabetes, 57, 3297, 10.2337/db08-0805 Studies of Left Ventricular Dysfunction (SOLVD) Investigators, 1991, Effect of enalaparil on survival in patients with reduced left ventricular ejection fractions and congestive heart failure, N Engl J Med, 325, 293, 10.1056/NEJM199108013250501 Susic, 2009, Angiotensin blockade prevents salt-induced injury of the renal circulation in spontaneously hypertensive rats, Am J Nephrol, 29, 639, 10.1159/000195633 Susic, 2011, Salt-induced renal injury in SHR is mediated by AT1 receptor activation, J Hypertens., 29, 716, 10.1097/HJH.0b013e3283440683 Takeda, 2001, Effects of high sodium intake on cardiovascular aldosterone synthesis in stroke prone spontaneously hypertensive rats, J Hypertens, 19, 10.1097/00004872-200103001-00017 van Katz, 2001, Use of a biological pump to study chronic peptide hormone action in transgenic mice. Direct and indirect effects of angiotensin II on the heart, J Biol Chem, 276, 44012, 10.1074/jbc.M106132200 van Kats, 1998, Angiotensin production by the heart: a quantitative study in pigs with the use of radiolabelled angiotensin infusions, Circulation, 98, 73, 10.1161/01.CIR.98.1.73 Varagic, 2006, Myocardial fibrosis, impaired coronary hemodynamics, and biventricular dysfunction in salt-loaded SHR, Am J Physiol Heart Circ Physiol, 290, H1503, 10.1152/ajpheart.00970.2005 Varagic, 2008, AT1 receptor antagonism attenuates target organ effects of salt excess in SHRs without affecting pressure, Am J Physiol Heart Circ Physiol, 4, 117 Xu, 2010, Local angiotensin II aggravates cardiac remodeling in hypertension, Am J Physiol Heart Circ Physiol, 299, H1328, 10.1152/ajpheart.00538.2010 Yasuda, 2008, A novel mechanism of mechanical stress-induced angiotensin II type 1-receptor activation without the involvement of angiotensin II, Naunyn-Schmiedebergs Arch Pharmacol, 377, 393, 10.1007/s00210-007-0215-1 Yu, 1998, Salt induces myocardial and renal fibrosis in nortensive and hypertensive rats, Circulation, 98, 2621, 10.1161/01.CIR.98.23.2621 Yusuf, 2001, Ramipril and the development of diabetes, JAMA, 286, 1882, 10.1001/jama.286.15.1882 Zhao, 2000, Cardiac hypertrophy and cardiac renin–angiotensin system in Dahl rats on high salt intake, J Hypertens, 18, 1319, 10.1097/00004872-200018090-00018 Zou, 2004, Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II, Nat Cell Biol, 6, 499, 10.1038/ncb1137 Zhuo, 2007, Novel roles of intracrine angiotensin II and signalling mechanisms in kidney cells, J Renin Angiotensin Aldosterone Syst, 8, 23, 10.3317/jraas.2007.003