Immunohistological localization of melatonin in the rat digestive system

Cellular and Molecular Life Sciences - Tập 33 - Trang 662-663 - 1977
G. A. Bubenik1,2, G. M. Brown1,2, L. J. Grota1,2
1Clarke Institute of Psychiatry, Toronto, Canada.
2Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, USA

Tóm tắt

The highest amount of melatonin (M), localized immunohistologically, was found in rectum, decreasing in the order: colon, duodenum, caecum, esophagus, stomach, ileum and jejunum. No M was found in the liver, spleen or pancreas. The distribution of M corresponds with the localization of serotonin-producing argentaffin cells.

Tài liệu tham khảo

A. B. Lerner, J. D. Case, Y. Takahashi, T. H. Lee and W. Mori, J. Am. Chem. Soc.80, 2587 (1958). R. J. Reiter, Progr. Brain Res.39, 281 (1973). D. P. Cardinali and R. J. Wurtman, Endocrinology91, 247 (1972). D. P. Cardinali and J. M. Rosner, J. Neurochem.18, 1769 (1971). S. F. Pang, C. L. Ralph and D. P. Reilly, Gen. Comp. Endocrin.22, 499 (1974). S. F. Pang, G. M. Brown, L. J. Grota and R. L. Rodman, Fed. Proc.35, 691 (1976). G. A. Bubenik, G. M. Brown and L. J. Grota, Brain Res.118, 417 (1976). G. A. Bubenik, G. M. Brown and L. J. Grota, J. Histochem. Cytochem.24, 1173 (1976). G. A. Bubenik, G. M. Brown, I. Uhlir and L. J. Grota, Brain Res.81, 233 (1974). I. M. Kvetnoy, N. T. Raikhlin and V. N. Tolkachev, Dokl. Acad. Nauk USSR221, 226 (1975). N. T. Raikhlin, I. M. Kvetnoy and V. N. Tolkachev, Nature255, 344 (1975). L. J. Grota and G. M. Brown, Can. J. Biochem.52, 196 (1974). A. H. Coons, E. H. Leduc and J. M. Connely, J. exp. Med.102, 49 (1955). W. Bloom and D. W. Fawcet, in: A Textbook of Histology, 9th ed., p. 560. Saunders, Philadelphia 1968. D. I. Patt, G. R. Patt, in: Comparative Vertebrate Histology, p. 146. Harper & Row, New York 1969.