Immunobiography and the Heterogeneity of Immune Responses in the Elderly: A Focus on Inflammaging and Trained Immunity
Tóm tắt
Từ khóa
Tài liệu tham khảo
Franceschi, 2017, Inflammaging and ‘Garb-aging’, Trends Endocrinol Metab, 28, 199, 10.1016/j.tem.2016.09.005
Capri, 2014, The new antigenic ecospace of the globalized world and its impact on the immune system: the battleground of trade-off and antagonistic pleiotropy, Eco-immunology: Evolutive Aspects and Future Perspectives, 125, 10.1007/978-94-017-8712-3_7
Ottaviani, 1996, The neuroimmunology of stress from invertebrates to man, Prog Neurobiol, 8, 421, 10.1016/0301-0082(95)00049-6
Ottaviani, 1998, A new theory on the common evolutionary origin of natural immunity, inflammation and stress response: the invertebrate phagocytic immunocyte as an eye-witness, Domest Anim Endocrinol, 15, 291, 10.1016/S0739-7240(98)00021-6
Ottaviani, 2007, Common evolutionary origin of the immune and neuroendocrine systems: from morphological and functional evidence to in silico approaches, Trends Immunol, 28, 497, 10.1016/j.it.2007.08.007
Franceschi, 2000, Inflamm-aging. An evolutionary perspective on immunosenescence, Ann N Y Acad Sci, 908, 244, 10.1111/j.1749-6632.2000.tb06651.x
Tieri, 2010, Network, degeneracy and bow tie. Integrating paradigms and architectures to grasp the complexity of the immune system, Theor Biol Med Model, 7, 32, 10.1186/1742-4682-7-32
Grignolio, 2014, Towards a liquid self: how time, geography, and life experiences reshape the biological identity, Front Immunol, 5, 153, 10.3389/fimmu.2014.00153
Liepe, 2016, A large fraction of HLA class I ligands are proteasome-generated spliced peptides, Science, 354, 354, 10.1126/science.aaf4384
De Martinis, 2005, Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity, FEBS Lett, 579, 2035, 10.1016/j.febslet.2005.02.055
Ostan, 2008, Immunosenescence and immunogenetics of human longevity, Neuroimmunomodulation, 15, 224, 10.1159/000156466
Franceschi, 1995, Immunosenescence in humans: deterioration or remodelling?, Int Rev Immunol, 12, 57, 10.3109/08830189509056702
Franceschi, 2000, Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space, Vaccine, 18, 1717, 10.1016/S0264-410X(99)00513-7
Franceschi, 2007, Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans, Mech Ageing Dev, 128, 92, 10.1016/j.mad.2006.11.016
Franceschi, 2014, Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases, J Gerontol A Biol Sci Med Sci, 69, S4, 10.1093/gerona/glu057
Fagiolo, 1993, Increased cytokine production in mononuclear cells of healthy elderly people, Eur J Immunol, 23, 2375, 10.1002/eji.1830230950
Ferrucci, 2005, Proinflammatory state and circulating erythropoietin in persons with and without anemia, Am J Med, 118, 1288, 10.1016/j.amjmed.2005.06.039
de Gonzalo-Calvo, 2010, Differential inflammatory responses in aging and disease: TNF-alpha and IL-6 as possible biomarkers, Free Radic Biol Med, 49, 733, 10.1016/j.freeradbiomed.2010.05.019
Gerli, 2000, Chemokines, sTNF-Rs and sCD30 serum levels in healthy aged people and centenarians, Mech Ageing Dev, 121, 37, 10.1016/S0047-6374(00)00195-0
Mariani, 2006, Simultaneous evaluation of circulating chemokine and cytokine profiles in elderly subjects by multiplex technology: relationship with zinc status, Biogerontology, 7, 449, 10.1007/s10522-006-9060-8
Seidler, 2010, Age dependent alterations of monocyte subsets and monocyte-related chemokine pathways in healthy adults, BMC Immunol, 11, 30, 10.1186/1471-2172-11-30
Morrisette-Thomas, 2014, Inflamm-aging does not simply reflect increases in pro-inflammatory markers, Mech Ageing Dev, 139, 49, 10.1016/j.mad.2014.06.005
Ottaviani, 1997, The invertebrate phagocytic immunocyte: clues to a common evolution of immune and neuroendocrine systems, Immunol Today, 18, 169, 10.1016/S0167-5699(97)84663-4
Tauber, 2003, Metchnikoff and the phagocytosis theory, Nat Rev Mol Cell Biol, 4, 897, 10.1038/nrm1244
Coppé, 2010, The senescence-associated secretory phenotype: the dark side of tumor suppression, Annu Rev Pathol, 5, 99, 10.1146/annurev-pathol-121808-102144
Crişan, 2016, Innate immune memory: implications for host responses to damage-associated molecular patterns, Eur J Immunol, 46, 817, 10.1002/eji.201545497
Bekkering, 2014, Oxidized low-density lipoprotein induces longterm proinflammatory cytokine production and foam cell formation via epigenetic reprogramming of monocytes, Arterioscler Thromb Vasc Biol, 34, 1731, 10.1161/ATVBAHA.114.303887
Valdes-Ferrer, 2013, High-mobility group box 1 mediates persistent splenocyte priming in sepsis survivors: evidence from a murine model, Shock, 40, 492, 10.1097/SHK.0000000000000050
Crişan, 2015, Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra, Ann Rheum Dis, 75, 755, 10.1136/annrheumdis-2014-206564
Tamburini, 2016, The microbiome in early life: implications for health outcomes, Nat Med, 22, 713, 10.1038/nm.4142
Biagi, 2010, Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians, PLoS One, 5, e10667, 10.1371/journal.pone.0010667
Vatti, 2017, Original antigenic sin: a comprehensive review, J Autoimmun, 10.1016/j.jaut.2017.04.008
Netea, 2017, Trained immunity: an ancient way of remembering, Cell Host Microbe, 21, 297, 10.1016/j.chom.2017.02.003
Sticher, 1997, Systemic acquired resistance, Annu Rev Phytopathol, 35, 235, 10.1146/annurev.phyto.35.1.235
Durrant, 2004, Systemic acquired resistance, Annu Rev Phytopathol, 42, 185, 10.1146/annurev.phyto.42.040803.140421
Schmid-Hempel, 2013, Evolutionary parasitology: the integrated study of infections, immunology, Ecology and Genetics, 10.1093/acprof:oso/9780199229482.001.0001
Milutinovic, 2016, Immune priming in arthropods: an update focusing on the red flour beetle, Zoology, 119, 254, 10.1016/j.zool.2016.03.006
Tettamanti, 2003, Leech responses to tissue transplantation, Tissue Cell, 35, 199, 10.1016/S0040-8166(03)00027-2
Kurtz, 2005, Specific memory within innate immune systems, Trends Immunol, 26, 186, 10.1016/j.it.2005.02.001
Popescu, 2011, Telocytes – a novel type of interstitial cells, Recent Researches in Modern Medicine, 424
Cretoiu, 2016, Telocytes and their extracellular vesicles – evidence and hypotheses, Int J Mol Sci, 17, 1322, 10.3390/ijms17081322
Stout, 2014, Caenorhabditis elegans glia modulate neuronal activity and behavior, Front Cell Neurosci, 8, 67, 10.3389/fncel.2014.00067
Baranzini, 2017, Telocytes in invertebrates. Proceeding of XVIIIth scientific meeting of the Italian Association of Developmental and Comparative Immunobiology (IADCI), Invert Surv J, 14, 44
Popescu, 2011, Identification of telocytes in skeletal muscle interstitium: implication for muscle regeneration, J Cell Mol Med, 15, 1379, 10.1111/j.1582-4934.2011.01330.x
Cismaşiu, 2015, Telocytes transfer extracellular vesicles loaded with microRNAs to stem cells, J Cell Mol Med, 19, 351, 10.1111/jcmm.12529
Faussone-Pellegrini, 2016, Telocyte’s contacts, Semin Cell Dev Biol, 55, 3, 10.1016/j.semcdb.2016.01.036
Edelstein, 2016, Telocytes in their context with other intercellular communication agents, Semin Cell Dev Biol, 55, 9, 10.1016/j.semcdb.2016.03.010
Edelstein, 2014, Epigenetic aspects of telocytes/cordocytes: jacks of all trades, masters of most, Front Cell Neurosci, 8, 32, 10.3389/fncel.2014.00032
Tribouley, 1978, [Effect of bacillus Callmette Guerin (BCG) on the receptivity of nude mice to Schistosoma mansoni], C R Seances Soc Biol Fil, 172, 902
Van’t Wout, 1992, The role of BCG-PPDactivated macrophages in resistance against systemic candidiasis in mice, Scand J Immunol, 36, 713, 10.1111/j.1365-3083.1992.tb03132.x
Bistoni, 1988, Immunomodulation by a low-virulence, agerminative variant of Candida albicans. Further evidence for macrophage activation as one of the effector mechanisms of nonspecific anti-infectious protection, J Med Vet Mycol, 26, 285, 10.1080/02681218880000401
Klinman, 1999, Repeated administration of synthetic oligodeoxynucleotides expressing CpG motifs provides long-term protection against bacterial infection, Infect Immun, 67, 5658, 10.1128/IAI.67.11.5658-5663.1999
Netea, 2011, Trained immunity: a memory for innate host defense, Cell Host Microbe, 9, 355, 10.1016/j.chom.2011.04.006
Netea, 2016, Trained immunity: a program of innate immune memory in health and disease, Science, 352, aaf1098, 10.1126/science.aaf1098
Welsh, 2002, No one is naive: the significance of heterologous T-cell immunity, Nat Rev Immunol, 2, 417, 10.1038/nri820
Benn, 2013, A small jab – a big effect: nonspecific immunomodulation by vaccines, Trends Immunol, 34, 431, 10.1016/j.it.2013.04.004
Aaby, 2014, Nonspecific effects of neonatal and infant vaccination: public-health, immunological and conceptual challenges, Nat Immunol, 15, 895, 10.1038/ni.2961
Töpfer, 2015, Innate immune memory: the latest frontier of adjuvanticity, J Immunol Res, 2015, 478408, 10.1155/2015/478408
Quintin, 2012, Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes, Cell Host Microbe, 12, 223, 10.1016/j.chom.2012.06.006
Kleinnijenhuis, 2014, BCG-induced trained immunity in NK cells: role for non-specific protection to infection, Clin Immunol, 155, 213, 10.1016/j.clim.2014.10.005
Dou, 2015, Influenza vaccine induces intracellular immune memory of human NK cells, PLoS One, 10, e0121258, 10.1371/journal.pone.0121258
Takeuchi, 2011, IL-17 production by gammadelta T cells is important for the antitumor effect of Mycobacterium bovis bacillus Calmette-Guerin treatment against bladder cancer, Eur J Immunol, 41, 246, 10.1002/eji.201040773
Fowler, 2012, Mycobacteria activate gammadelta T-cell anti-tumour responses via cytokines from type 1 myeloid dendritic cells: a mechanism of action for cancer immunotherapy, Cancer Immunol Immunother, 61, 535, 10.1007/s00262-011-1121-4
Saeed, 2014, Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity, Science, 345, 1251086, 10.1126/science.1251086
Cheng, 2014, mTOR- and HIF-1alpha-mediated aerobic glycolysis as metabolic basis for trained immunity, Science, 345, 1250684, 10.1126/science.1250684
Luna, 2012, The epigenetic machinery controlling transgenerational systemic acquired resistance, Plant Signal Behav, 7, 615, 10.4161/psb.20155
Arts, 2016, Immunometabolic circuits in trained immunity, Semin Immunol, 28, 425, 10.1016/j.smim.2016.09.002
Liu, 2012, NAD+-dependent sirtuin 1 and 6 proteins coordinate a switch from glucose to fatty acid oxidation during the acute inflammatory response, J Biol Chem, 287, 25758, 10.1074/jbc.M112.362343
Latham, 2012, Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression, Nucleic Acids Res, 40, 4794, 10.1093/nar/gks066
Kleinnijenhuis, 2012, Bacille Calmette-Guérin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes, Proc Natl Acad Sci U S A, 109, 17537, 10.1073/pnas.1202870109
Burgess, 2014, Bone marrow dendritic cells from mice with an altered microbiota provide interleukin 17A-dependent protection against Entamoeba histolytica colitis, MBio, 5, e01817, 10.1128/mBio.01817-14
Wen, 2017, Factors influencing the gut microbiota, inflammation, and type 2 diabetes, J Nutr, 10.3945/jn.116.240754
Schlums, 2015, Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function, Immunity, 42, 443, 10.1016/j.immuni.2015.02.008
Lee, 2015, Epigenetic modification and antibody-dependent expansion of memory-like NK cells in human cytomegalovirus-infected individuals, Immunity, 42, 431, 10.1016/j.immuni.2015.02.013
Gensous, 2017, The epigenetic landscape of age-related diseases: the geroscience perspective, Biogerontology, 10.1007/s10522-017-9695-7
Krol, 2010, The widespread regulation of microRNAs biogenesis, function and decay, Nat Rev Genet, 11, 597, 10.1038/nrg2843
O’Connell, 2009, Inositol phosphatase SHIP1 is a primary target of miR-155, Proc Natl Acad Sci U S A, 106, 7113, 10.1073/pnas.0902636106
Olivieri, 2015, DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging, Oncotarget, 6, 35509, 10.18632/oncotarget.5899
Frasca, 2015, MicroRNAs miR-155 and miR-16 decrease AID and E47 in B cells from elderly individuals, J Immunol, 195, 2134, 10.4049/jimmunol.1500520
Ancuta, 2003, Fractalkine preferentially mediates arrest and migration of CD16+ monocytes, J Exp Med, 197, 1701, 10.1084/jem.20022156
Qian, 2012, Age-associated elevation in TLR5 leads to increased inflammatory responses in the elderly, Aging Cell, 11, 104, 10.1111/j.1474-9726.2011.00759.x
van Duin, 2007, Age-associated defect in human TLR-1/2 function, J Immunol, 178, 970, 10.4049/jimmunol.178.2.970
Panda, 2010, Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response, J Immunol, 184, 2518, 10.4049/jimmunol.0901022
Qian, 2011, Impaired interferon signaling in dendritic cells from older donors infected in vitro with West Nile virus, J Infect Dis, 203, 1415, 10.1093/infdis/jir048
Metcalf, 2015, Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors, Aging Cell, 14, 421, 10.1111/acel.12320
Dobrovolskaia, 2002, Toll receptors, CD14, and macrophage activation and deactivation by LPS, Microbes Infect, 4, 903, 10.1016/S1286-4579(02)01613-1
Polycarpou, 2016, Mycobacterium leprae activates toll-like receptor-4 signaling and expression on macrophages depending on previous bacillus Calmette-Guerin vaccination, Front Cell Infect Microbiol, 6, 72, 10.3389/fcimb.2016.00072
Le Garff-Tavernier, 2010, Human NK cells display major phenotypic and functional changes over the life span, Aging Cell, 9, 527, 10.1111/j.1474-9726.2010.00584.x
Campos, 2014, Proinflammatory status influences NK cells subsets in the elderly, Immunol Lett, 162, 298, 10.1016/j.imlet.2014.06.015
Pinti, 2016, Aging of the immune system: focus on inflammation and vaccination, Eur J Immunol, 46, 2286, 10.1002/eji.201546178
Della Chiesa, 2014, Human NK cell response to pathogens, Semin Immunol, 26, 152, 10.1016/j.smim.2014.02.001
Adib-Conquy, 2014, TLR-mediated activation of NK cells and their role in bacterial/viral immune responses in mammals, Immunol Cell Biol, 92, 256, 10.1038/icb.2013.99
Chalifour, 2004, Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin production, Blood, 104, 1778, 10.1182/blood-2003-08-2820
Sivori, 2004, CpG and double-stranded RNA trigger human NK cells by toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells, Proc Natl Acad Sci U S A, 101, 10116, 10.1073/pnas.0403744101
Hart, 2005, TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production, J Immunol, 175, 1636, 10.4049/jimmunol.175.3.1636
Horton, 2015, NKp44 and natural cytotoxicity receptors as damage-associated molecular pattern recognition receptors, Front Immunol, 6, 31, 10.3389/fimmu.2015.00031
Lopez-Verges, 2010, CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+NK-cell subset, Blood, 116, 3865, 10.1182/blood-2010-04-282301
Huntington, 2007, NK cell maturation and peripheral homeostasis is associated with KLRG1 up-regulation, J Immunol, 178, 4764, 10.4049/jimmunol.178.8.4764
Muller-Durovic, 2016, Killer cell lectin-like receptor G1 inhibits NK cell function through activation of adenosine 5’-monophosphate-activated protein kinase, J Immunol, 197, 2891, 10.4049/jimmunol.1600590
Kared, 2016, CD57 in human natural killer cells and T-lymphocytes, Cancer Immunol Immunother, 65, 441, 10.1007/s00262-016-1803-z
Bjorkstrom, 2010, Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education, Blood, 116, 3853, 10.1182/blood-2010-04-281675
Lugli, 2014, NK cell subset redistribution during the course of viral infections, Front Immunol, 5, 390, 10.3389/fimmu.2014.00390
Hendricks, 2014, Cutting edge: NKG2C(hi)CD57+NK cells respond specifically to acute infection with cytomegalovirus and not Epstein–Barr virus, J Immunol, 192, 4492, 10.4049/jimmunol.1303211
Heath, 2016, NKG2C(+)CD57(+) natural killer cell expansion parallels cytomegalovirus-specific CD8(+) T cell evolution towards senescence, J Immunol Res, 2016, 7470124, 10.1155/2016/7470124
Voehringer, 2002, Lack of proliferative capacity of human effector and memory T cells expressing killer cell lectin like receptor G1 (KLRG1), Blood, 100, 3698, 10.1182/blood-2002-02-0657
Alonso-Arias, 2011, NKG2D expression in CD4+ T lymphocytes as a marker of senescence in the aged immune system, Age (Dordr), 33, 591, 10.1007/s11357-010-9200-6
Melis, 2014, Senescence marker killer cell lectin-like receptor G1 (KLRG1) contributes to TNF-α production by interaction with its soluble E-cadherin ligand in chronically inflamed joints, Ann Rheum Dis, 73, 1223, 10.1136/annrheumdis-2013-203881
Pereira, 2016, Convergence of innate and adaptive immunity during human aging, Front Immunol, 7, 445, 10.3389/fimmu.2016.00445
Vallejo, 2011, Expansions of NK-like alphabeta T cells with chronologic aging: novel lymphocyte effectors that compensate for functional deficits of conventional NK cells and T cells, Ageing Res Rev, 10, 354, 10.1016/j.arr.2010.09.006
Pita-López, 2016, Adaptive memory of human NK-like CD8(+) T-cells to aging, and viral and tumor antigens, Front Immunol, 7, 616, 10.3389/fimmu.2016.00616
Gogoi, 2014, Involvement of notch in activation and effector functions of gammadelta T cells, J Immunol, 192, 2054, 10.4049/jimmunol.1300369
Dar, 2014, Insights into the relationship between Toll like receptors and gamma delta T cell responses, Front Immunol, 5, 366, 10.3389/fimmu.2014.00366
Argentati, 2002, Numerical and functional alterations of circulating gammadelta T lymphocytes in aged people and centenarians, J Leukoc Biol, 72, 65, 10.1189/jlb.72.1.65
Roux, 2013, Differential impact of age and cytomegalovirus infection on the gammadelta T cell compartment, J Immunol, 191, 1300, 10.4049/jimmunol.1202940
Wistuba-Hamprecht, 2013, Age-associated alterations in gammadelta T-cells are present predominantly in individuals infected with cytomegalovirus, Immun Ageing, 10, 26, 10.1186/1742-4933-10-26
Alejenef, 2014, Cytomegalovirus drives Vδ2neg γδ T cell inflation in many healthy virus carriers with increasing age, Clin Exp Immunol, 176, 418, 10.1111/cei.12297
Guerville, 2015, TCR-dependent sensitization of human γδ T cells to non-myeloid IL-18 in cytomegalovirus and tumor stress surveillance, Oncoimmunology, 4, e1003011, 10.1080/2162402X.2014.1003011
Martinez-Gonzalez, 2016, Allergen-experienced group 2 innate lymphoid cells acquire memory-like properties and enhance allergic lung inflammation, Immunity, 45, 198, 10.1016/j.immuni.2016.06.017
Fulop, 2016, From inflamm-aging to immune-paralysis: a slippery slope during aging for immune adaptation, Biogerontology, 17, 147, 10.1007/s10522-015-9615-7
Christ, 2016, Long-term activation of the innate immune system in atherosclerosis, Semin Immunol, 28, 384, 10.1016/j.smim.2016.04.004