Technologies towards antibiotic resistance genes (ARGs) removal from aquatic environment: A critical review

Ahmed, 2020, Efficient inactivation of antibiotic resistant bacteria and antibiotic resistance genes by photo-Fenton process under visible LED light and neutral pH, Water Res., 179, 10.1016/j.watres.2020.115878 Alekshun, 2007, Molecular mechanisms of antibacterial multidrug resistance, Cell, 128, 1037, 10.1016/j.cell.2007.03.004 Allen, 2010, Call of the wild: antibiotic resistance genes in natural environments, Nat. Rev. Microbiol., 8, 251, 10.1038/nrmicro2312 Amarasiri, 2019, Understanding human health risks caused by antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARG) in water environments: current knowledge and questions to be answered, Crit. Rev. Environ. Sci. Technol., 50, 2016, 10.1080/10643389.2019.1692611 Ameta, 2018 Ashbolt, 2013, Human health risk assessment (HHRA) for environmental development and transfer of antibiotic resistance, Environ. Health Perspect., 121, 993, 10.1289/ehp.1206316 Barancheshme, 2018, Strategies to combat antibiotic resistance in the wastewater treatment plants, Front. Microbiol., 8, 12, 10.3389/fmicb.2017.02603 Baygi, 2020, Microbial community and antibiotic resistance profiles of biomass and effluent are distinctly affected by antibiotics addition to an anaerobic membrane bioreactor, Environ. Sci. Water Res. Berglund, 2015, Environmental dissemination of antibiotic resistance genes and correlation to anthropogenic contamination with antibiotics, Infect. Ecol. Epidemiol., 5, 28564 Berglund, 2019, Identification and reconstruction of novel antibiotic resistance genes from metagenomes, Microbiome, 7, 52, 10.1186/s40168-019-0670-1 Billard-Pomares, 2014, Characterization of a P1-like bacteriophage carrying an SHV-2 extended-spectrum β-lactamase from an Escherichia coli strain, Antimicrob. Agents Chemother., 58, 6550, 10.1128/AAC.03183-14 Blair, 2015, Molecular mechanisms of antibiotic resistance, Nat. Rev. Microbiol., 13, 42, 10.1038/nrmicro3380 Bytesnikova, 2019, Graphene oxide as a tool for antibiotic-resistant gene removal: a review, Environ. Sci. Pollut. Res., 26, 20148, 10.1007/s11356-019-05283-y Cantón, 2012, CTX-M enzymes: origin and diffusion, Front. Microbiol., 3, 110, 10.3389/fmicb.2012.00110 Chen, 2019, Catalytic ozonation of sulfamethoxazole over Fe3O4/Co3O4 composites, Chemosphere, 234, 14, 10.1016/j.chemosphere.2019.06.014 Chen, 2016, Removal of antibiotics and antibiotic resistance genes from domestic sewage by constructed wetlands: optimization of wetland substrates and hydraulic loading, Sci. Total Environ., 565, 240, 10.1016/j.scitotenv.2016.04.176 Chen, 2019, Fate and removal of antibiotics and antibiotic resistance genes in hybrid constructed wetlands, Environ. Pollut., 249, 894, 10.1016/j.envpol.2019.03.111 Chen, 2019, High-throughput profiling of antibiotic resistance gene dynamic in a drinking water river-reservoir system, Water Res., 149, 179, 10.1016/j.watres.2018.11.007 Cheng, 2017, Removal of antibiotic-resistant bacteria and antibiotic resistance genes affected by varying degrees of fouling on anaerobic microfiltration membranes, Environ. Sci. Technol., 51, 12200, 10.1021/acs.est.7b03798 Cheng, 2020, Removal of antibiotic resistance genes in an algal-based wastewater treatment system employing Galdieria sulphuraria: a comparative study, Sci. Total Environ., 711, 10.1016/j.scitotenv.2019.134435 Chu, 2019, Degradation of antibiotics and antibiotic resistance genes in erythromycin fermentation residues using radiation coupled with peroxymonosulfate oxidation, Waste Manag., 96, 190, 10.1016/j.wasman.2019.07.031 Chu, 2019, Degradation of macrolide antibiotic erythromycin and reduction of antimicrobial activity using persulfate activated by gamma radiation in different water matrices, Chem. Eng. J., 361, 156, 10.1016/j.cej.2018.12.072 Chu, 2020, Degradation of antibiotics and inactivation of antibiotic resistance genes (ARGs) in Cephalosporin C fermentation residues using ionizing radiation, ozonation and thermal treatment, J. Hazard. Mater., 382, 10.1016/j.jhazmat.2019.121058 Cui, 2018, Amendment soil with biochar to control antibiotic resistance genes under unconventional water resources irrigation: proceed with caution, Environ. Pollut., 240, 475, 10.1016/j.envpol.2018.04.143 Davies, 2010, Origins and evolution of antibiotic resistance, MMBR, 74, 417, 10.1128/MMBR.00016-10 Destiani, 2019, Chlorination and ultraviolet disinfection of antibiotic-resistant bacteria and antibiotic resistance genes in drinking water, AIMS Environ. Sci., 6, 222, 10.3934/environsci.2019.3.222 Ding, 2019, Enhanced inactivation of antibiotic-resistant bacteria isolated from secondary effluents by gC3N4 photocatalysis, Environ. Sci. Pollut. Res., 26, 18730, 10.1007/s11356-019-05080-7 Dodd, 2012, Potential impacts of disinfection processes on elimination and deactivation of antibiotic resistance genes during water and wastewater treatment, J. Environ. Monit., 14, 1754, 10.1039/c2em00006g Farooq, 2009, The effect of ultrasonic irradiation on the anaerobic digestion of activated sludge, World Appl. Sci. J., 6, 234 Gao, 2020, Effects of persulfate treatment on antibiotic resistance genes abundance and the bacterial community in secondary effluent, Chem. Eng. J., 382, 10.1016/j.cej.2019.05.221 Gaze, 2011, Impacts of anthropogenic activity on the ecology of class 1 integrons and integron-associated genes in the environment, ISME J., 5, 1253, 10.1038/ismej.2011.15 Ghernaout, 2020, Advanced oxidation processes for wastewater treatment: facts and future trends, Open Access Lib. J., 7, 1 Giannakis, 2018, Solar photo-Fenton disinfection of 11 antibiotic-resistant bacteria (ARB) and elimination of representative AR genes. Evidence that antibiotic resistance does not imply resistance to oxidative treatment, Water Res., 143, 334, 10.1016/j.watres.2018.06.062 Grenni, 2018, Ecological effects of antibiotics on natural ecosystems: a review, Microchem. J., 136, 25, 10.1016/j.microc.2017.02.006 Griffith, 1928, The significance of pneumococcal types, Epidemiol. Infect., 27, 113 Guo, 2017, H2O2 and/or TiO2 photocatalysis under UV irradiation for the removal of antibiotic resistant bacteria and their antibiotic resistance genes, J. Hazard. Mater., 323, 710, 10.1016/j.jhazmat.2016.10.041 Guo, 2017, Metagenomic analysis reveals wastewater treatment plants as hotspots of antibiotic resistance genes and mobile genetic elements, Water Res., 123, 468, 10.1016/j.watres.2017.07.002 Guo, 2020, 9 - Anaerobic membrane bioreactors for antibiotic wastewater treatment, 219 Hall, 2017, Positive selection inhibits gene mobilization and transfer in soil bacterial communities, Nat. Ecol. Evol., 1, 1348, 10.1038/s41559-017-0250-3 He, 2016, Discharge of swine wastes risks water quality and food safety: antibiotics and antibiotic resistance genes from swine sources to the receiving environments, Environ. Int., 92–93, 210, 10.1016/j.envint.2016.03.023 He, 2018, Evaluation of attenuation of pharmaceuticals, toxic potency, and antibiotic resistance genes in constructed wetlands treating wastewater effluents, Sci. Total Environ., 631, 1572, 10.1016/j.scitotenv.2018.03.083 He, 2020, Antibiotic resistance genes from livestock waste: occurrence, dissemination, and treatment, NPJ Clean Water, 3, 1, 10.1038/s41545-020-0051-0 Hiller, 2019, Antibiotic microbial resistance (AMR) removal efficiencies by conventional and advanced wastewater treatment processes: a review, Sci. Total Environ., 685, 596, 10.1016/j.scitotenv.2019.05.315 Hu, 2013, Metagenome-wide analysis of antibiotic resistance genes in a large cohort of human gut microbiota, Nat. Commun., 4, 2151, 10.1038/ncomms3151 Hu, 2020, Pretreatment of antibiotic fermentation residues by combined ultrasound and alkali for enhancing biohydrogen production, J. Clean. Prod., 268, 10.1016/j.jclepro.2020.122190 Huang, 2019, CuO and ZnO nanoparticles drive the propagation of antibiotic resistance genes during sludge anaerobic digestion: possible role of stimulated signal transduction, Environ. Sci. Nano, 6, 528, 10.1039/C8EN00370J Ji, 2012, Antibiotic resistance gene abundances associated with antibiotics and heavy metals in animal manures and agricultural soils adjacent to feedlots in Shanghai; China, J. Hazard. Mater., 235, 178, 10.1016/j.jhazmat.2012.07.040 Jiménez-Tototzintle, 2018, Removal of contaminants of emerging concern (CECs) and antibiotic resistant bacteria in urban wastewater using UVA/TiO2/H2O2 photocatalysis, Chemosphere, 210, 449, 10.1016/j.chemosphere.2018.07.036 Kappell, 2018, Removal of antibiotic resistance genes in an anaerobic membrane bioreactor treating primary clarifier effluent at 20 °C, Environ. Sci. Water Res., 4, 1783, 10.1039/C8EW00270C Karaolia, 2018, Removal of antibiotics, antibiotic-resistant bacteria and their associated genes by graphene-based TiO2 composite photocatalysts under solar radiation in urban wastewaters, Appl. Catal. B Environ., 224, 810, 10.1016/j.apcatb.2017.11.020 Karkman, 2018, Antibiotic-resistance genes in waste water, Trends Microbiol., 26, 220, 10.1016/j.tim.2017.09.005 Kucukunsal, 2019, Removal of antibiotic resistance genes in various water resources recovery facilities, Water Environ. Res., 92, 911, 10.1002/wer.1286 Lamas, 2016, High-throughput platforms in real-time PCR and applications, Polym. Chain React. Biomed. Appl., 15 Lee, 2017, Quantitative and qualitative changes in antibiotic resistance genes after passing through treatment processes in municipal wastewater treatment plants, Sci. Total Environ., 605–606, 906, 10.1016/j.scitotenv.2017.06.250 Lerminiaux, 2018, Horizontal transfer of antibiotic resistance genes in clinical environments, Can. J. Microbiol., 65, 34, 10.1139/cjm-2018-0275 Li, 2015, Metagenomic and network analysis reveal wide distribution and co-occurrence of environmental antibiotic resistance genes, ISME J., 9, 2490, 10.1038/ismej.2015.59 Li, 2019, Dissecting horizontal and vertical gene transfer of antibiotic resistance plasmid in bacterial community using microfluidics, Environ. Int., 131, 10.1016/j.envint.2019.105007 Li, 2015, Antibiotic-resistant genes and antibiotic-resistant bacteria in the effluent of urban residential areas, hospitals, and a municipal wastewater treatment plant system, Environ. Sci. Pollut. Res., 22, 4587, 10.1007/s11356-014-3665-2 Li, 2016, Occurrence and removal of antibiotics and the corresponding resistance genes in wastewater treatment plants: effluents’ influence to downstream water environment, Environ. Sci. Pollut. Res., 23, 6826, 10.1007/s11356-015-5916-2 Li, 2020, Occurrence and fate of antibiotic residues and antibiotic resistance genes in a reservoir with ecological purification facilities for drinking water sources, Sci. Total Environ., 707, 10.1016/j.scitotenv.2019.135276 Li, 2020, Microbial electro-Fenton: a promising system for antibiotics resistance genes degradation and energy generation, Sci. Total Environ., 699, 10.1016/j.scitotenv.2019.134160 Li, 2020, Vertical transmission of gut microbiome and antimicrobial resistance genes in infants exposed to antibiotics at birth, J. Infect. Dis. Liao, 2018, Removal of intl1 and associated antibiotics resistant genes in water, sewage sludge and livestock manure treatments, Rev. Environ. Sci. Biotechnol., 17, 471, 10.1007/s11157-018-9469-y Ling, 2015, A new antibiotic kills pathogens without detectable resistance, Nature, 517, 455, 10.1038/nature14098 Liu, 2017, Antibiotic pollution in marine food webs in Laizhou Bay, North China: trophodynamics and human exposure implication, Environ. Sci. Technol., 51, 2392, 10.1021/acs.est.6b04556 Liu, 2018, Chlorine disinfection increases both intracellular and extracellular antibiotic resistance genes in a full-scale wastewater treatment plant, Water Res., 136, 131, 10.1016/j.watres.2018.02.036 Liu, 2018, Metagenomic analysis of antibiotic resistance genes (ARGs) during refuse decomposition, Sci. Total Environ., 634, 1231, 10.1016/j.scitotenv.2018.04.048 Liu, 2019, A review on removing antibiotics and antibiotic resistance genes from wastewater by constructed wetlands: performance and microbial response, Environ. Pollut., 254, 10.1016/j.envpol.2019.112996 Liu, 2019, The impacts of different high-throughput profiling approaches on the understanding of bacterial antibiotic resistance genes in a freshwater reservoir, Sci. Total Environ., 693, 10.1016/j.scitotenv.2019.133585 Liu, 2019, Occurrence and fate of antibiotics and antibiotic resistance genes in typical urban water of Beijing, China, Environ. Pollut., 246, 163, 10.1016/j.envpol.2018.12.005 Mahfouz, 2018, High genomic diversity of multi-drug resistant wastewater Escherichia coli, Sci. Rep., 8, 8928, 10.1038/s41598-018-27292-6 Manaia, 2017, Assessing the risk of antioiotic resistance transmission from the environment to humans: non-direct proportionality between abundance and risk, Trends Microbiol., 25, 173, 10.1016/j.tim.2016.11.014 Martínez, 2008, Antibiotics and antibiotic resistance genes in natural environments, Science, 321, 365, 10.1126/science.1159483 Michael-Kordatou, 2018, The role of operating parameters and oxidative damage mechanisms of advanced chemical oxidation processes in the combat against antibiotic-resistant bacteria and resistance genes present in urban wastewater, Water Res., 129, 208, 10.1016/j.watres.2017.10.007 Miller, 2016, Survival of antibiotic resistant bacteria and horizontal gene transfer control antibiotic resistance gene content in anaerobic digesters, Front. Microbiol., 7, 263, 10.3389/fmicb.2016.00263 Moubareck, 2003, Multiple antibiotic resistance gene transfer from animal to human enterococci in the digestive tract of gnotobiotic mice, Antimicrob. Agents Chemother., 47, 2993, 10.1128/AAC.47.9.2993-2996.2003 Negreanu, 2012, Impact of treated wastewater irrigation on antibiotic resistance in agricultural soils, Environ. Sci. Technol., 46, 4800, 10.1021/es204665b Niu, 2016, Occurrence and distribution of antibiotic resistance genes in the coastal area of the Bohai Bay, China, Mar. Pollut. Bull., 107, 245, 10.1016/j.marpolbul.2016.03.064 Pallares-Vega, 2019, Determinants of presence and removal of antibiotic resistance genes during WWTP treatment: a cross-sectional study, Water Res., 161, 319, 10.1016/j.watres.2019.05.100 Pei, 2019, State of the art of tertiary treatment technologies for controlling antibiotic resistance in wastewater treatment plants, Environ. Int., 131, 10.1016/j.envint.2019.105026 Qiu, 2020, Removal of antibiotic resistant microbes by Fe (II)-activated persulfate oxidation, J. Hazard. Mater., 396, 10.1016/j.jhazmat.2020.122733 Qiu, 2012, Nanoalumina promotes the horizontal transfer of multiresistance genes mediated by plasmids across genera, Proc. Natl. Acad. Sci., 109, 4944, 10.1073/pnas.1107254109 Rebecca Anisha, 2020, Performance evaluation of combined ultraviolet-ultrasonic technologies in removal of sulfonamide and tetracycline resistant Escherichia coli from domestic effluents, J. Water Sanit. Hyg. Dev., 10, 276, 10.2166/washdev.2020.144 Ren, 2018, Photocatalytic reactive ultrafiltration membrane for removal of antibiotic resistant bacteria and antibiotic resistance genes from wastewater effluent, Environ. Sci. Technol., 52, 8666, 10.1021/acs.est.8b01888 Rocha, 2020, Inter-laboratory calibration of quantitative analyses of antibiotic resistance genes, J. Environ. Chem. Eng., 8, 10.1016/j.jece.2018.02.022 Rodríguez-Chueca, 2019, Assessment of full-scale tertiary wastewater treatment by UV-C based-AOPs: removal or persistence of antibiotics and antibiotic resistance genes?, Sci. Total Environ., 652, 1051, 10.1016/j.scitotenv.2018.10.223 Saha, 2020, Inactivation of antibiotic resistance gene by ternary nanocomposites of carbon nitride, reduced graphene oxide and iron oxide under visible light, Chem. Eng. J., 382, 10.1016/j.cej.2019.122857 Sanganyado, 2019, Antibiotic resistance in drinking water systems: occurrence, removal, and human health risks, Sci. Total Environ., 669, 785, 10.1016/j.scitotenv.2019.03.162 Sharma, 2019, Elimination of antibiotic resistance genes and control of horizontal transfer risk by UV-based treatment of drinking water: a mini review, Front. Environ. Sci. Eng., 13, 37, 10.1007/s11783-019-1122-7 Shen, 2019, Degradation of antibiotics and antibiotic resistance genes in fermentation residues by ionizing radiation: a new insight into a sustainable management of antibiotic fermentative residuals, J. Environ. Manag., 232, 171, 10.1016/j.jenvman.2018.11.050 Smith, 2005, Agricultural antibiotics and human health - does antibiotic use in agriculture have a greater impact than hospital use?, PLos Med., 2, 731 Song, 2018, Vertical up-flow constructed wetlands exhibited efficient antibiotic removal but induced antibiotic resistance genes in effluent, Chemosphere, 203, 434, 10.1016/j.chemosphere.2018.04.006 Stange, 2019, Comparative removal of antibiotic resistance genes during chlorination, ozonation, and UV treatment, Int. J. Hyg. Environ. Health, 222, 541, 10.1016/j.ijheh.2019.02.002 Su, 2017, Occurrence and temporal variation of antibiotic resistance genes (ARGs) in shrimp aquaculture: ARGs dissemination from farming source to reared organisms, Sci. Total Environ., 607–608, 357, 10.1016/j.scitotenv.2017.07.040 Subirats, 2016, Metagenomic analysis reveals that bacteriophages are reservoirs of antibiotic resistance genes, Int. J. Antimicrob. Agents, 48, 163, 10.1016/j.ijantimicag.2016.04.028 Sun, 2018, Impacts of biochar on the environmental risk of antibiotic resistance genes and mobile genetic elements during anaerobic digestion of cattle farm wastewater, Bioresour. Technol., 256, 342, 10.1016/j.biortech.2018.02.052 Thomas, 2005, Mechanisms of, and barriers to, horizontal gene transfer between bacteria, Nat. Rev. Microbiol., 3, 711, 10.1038/nrmicro1234 Vezina, 1975, Rapamycin (AY-22, 989), a new antifungal antibiotic, J. Antibiot., 28, 721, 10.7164/antibiotics.28.721 Virto, 2005, Membrane damage and microbial inactivation by chlorine in the absence and presence of a chlorine-demanding substrate, Appl. Environ. Microbiol., 71, 5022, 10.1128/AEM.71.9.5022-5028.2005 Wang, 2020, More effective removal of antibiotic resistance genes from excess sludge by microwave integrated fenton treatment, Int. Biodeterior. Biodegrad., 149, 10.1016/j.ibiod.2020.104920 Wang, 2019, Distribution and removal of antibiotic resistance genes during anaerobic sludge digestion with alkaline, thermal hydrolysis and ultrasonic pretreatments, Front. Environ. Sci. Eng., 13, 43, 10.1007/s11783-019-1127-2 Wang, 2019, Comparative analysis of intracellular and extracellular antibiotic resistance gene abundance in anaerobic membrane bioreactor effluent, BioRxiv Wang, 2015, Enhanced horizontal transfer of antibiotic resistance genes in freshwater microcosms induced by an ionic liquid, PLoS One, 10 Wang, 2019, Antiepileptic drug carbamazepine promotes horizontal transfer of plasmid-borne multi-antibiotic resistance genes within and across bacterial genera, ISME J., 13, 509, 10.1038/s41396-018-0275-x Waseem, 2019, Contributions and challenges of high throughput qPCR for determining antimicrobial resistance in the environment: a critical review, Molecules, 24, 163, 10.3390/molecules24010163 Waseem, 2020, Chapter 14 - Global trends in ARGs measured by HT-qPCR platforms, 206 Wei, 2020, Degradation of phenol with heterogeneous catalytic ozonation enhanced by high gravity technology, J. Clean. Prod., 248, 10.1016/j.jclepro.2019.119179 von Wintersdorff, 2016, Dissemination of antimicrobial resistance in microbial ecosystems through horizontal gene transfer, Front. Microbiol., 7, 173, 10.3389/fmicb.2016.00173 Wu, 2020, Fate and removal of antibiotic resistance genes in heavy metals and dye co-contaminated wastewater treatment system amended with β-cyclodextrin functionalized biochar, Sci. Total Environ., 723, 10.1016/j.scitotenv.2020.137991 Xiang, 2020, Biochar technology in wastewater treatment: a critical review, Chemosphere, 252, 10.1016/j.chemosphere.2020.126539 Xie, 2020, Feasibility study on applying the iron-activated persulfate system as a pre-treatment process for clofibric acid selective degradation in municipal wastewater, Sci. Total Environ., 739, 10.1016/j.scitotenv.2020.140020 Xu, 2016, Occurrence and distribution of antibiotics, antibiotic resistance genes in the urban rivers in Beijing, China, Environ. Pollut., 213, 833, 10.1016/j.envpol.2016.03.054 Xue, 2019, Critical review of ARGs reduction behavior in various sludge and sewage treatment processes in wastewater treatment plants, Crit. Rev. Environ. Sci. Technol., 49, 1623, 10.1080/10643389.2019.1579629 Yadav, 2019, Exploration of activated sludge resistome using metagenomics, Sci. Total Environ., 692, 1155, 10.1016/j.scitotenv.2019.07.267 Yan, 2019, The effect of bioelectrochemical systems on antibiotics removal and antibiotic resistance genes: a review, Chem. Eng. J., 358, 1421, 10.1016/j.cej.2018.10.128 Yang, 2018, Antibiotics and antibiotic resistance genes in global lakes: a review and meta-analysis, Environ. Int., 116, 60, 10.1016/j.envint.2018.04.011 Yang, 2019, Metagenomic insights into the abundance and composition of resistance genes in aquatic environments: influence of stratification and geography, Environ. Int., 127, 371, 10.1016/j.envint.2019.03.062 Yi, 2017, Removal of selected PPCPs, EDCs, and antibiotic resistance genes in landfill leachate by a full-scale constructed wetlands system, Water Res., 121, 46, 10.1016/j.watres.2017.05.008 Yoon, 2017, Inactivation efficiency of plasmid-encoded antibiotic resistance genes during water treatment with chlorine, UV, and UV/H2O2, Water Res., 123, 783, 10.1016/j.watres.2017.06.056 Yu, 2020, Inactivation and change of tetracycline-resistant Escherichia coli in secondary effluent by visible light-driven photocatalytic process using Ag/AgBr/g-C3N4, Sci. Total Environ., 705, 10.1016/j.scitotenv.2019.135639 Zhang, 2015, Comprehensive evaluation of antibiotics emission and fate in the river basins of China: source analysis, multimedia modeling, and linkage to bacterial resistance, Environ. Sci. Technol., 49, 6772, 10.1021/acs.est.5b00729 Zhang, 2018, A system composed of a biofilm electrode reactor and a microbial fuel cell-constructed wetland exhibited efficient sulfamethoxazole removal but induced sul genes, Bioresour. Technol., 256, 224, 10.1016/j.biortech.2018.02.023 Zhang, 2020, Constructed wetland revealed efficient sulfamethoxazole removal but enhanced the spread of antibiotic resistance genes, Molecules, 25, 834, 10.3390/molecules25040834 Zhang, 2019, Removal of antibiotic resistance genes and control of horizontal transfer risk by UV, chlorination and UV/chlorination treatments of drinking water, Chem. Eng. J., 358, 589, 10.1016/j.cej.2018.09.218 Zhang, 2015, Inactivation of antibiotic resistance genes in municipal wastewater effluent by chlorination and sequential UV/chlorination disinfection, Sci. Total Environ., 512–513, 125, 10.1016/j.scitotenv.2015.01.028 Zhang, 2016, Reduction of antibiotic resistance genes in municipal wastewater effluent by advanced oxidation processes, Sci. Total Environ., 550, 184, 10.1016/j.scitotenv.2016.01.078 Zhang, 2017, Subinhibitory concentrations of disinfectants promote the horizontal transfer of multidrug resistance genes within and across genera, Environ. Sci. Technol., 51, 570, 10.1021/acs.est.6b03132 Zhang, 2019, Erythromycin degradation and ERY-resistant gene inactivation in erythromycin mycelial dreg by heat-activated persulfate oxidation, Chem. Eng. J., 358, 1446, 10.1016/j.cej.2018.10.157 Zhao, 2019, Oxidative degradation of amoxicillin in aqueous solution by thermally activated persulfate, J. Chem., 2019, 1, 10.1155/2019/4712807 Zheng, 2017, Effects and mechanisms of ultraviolet, chlorination, and ozone disinfection on antibiotic resistance genes in secondary effluents of municipal wastewater treatment plants, Chem. Eng. J., 317, 309, 10.1016/j.cej.2017.02.076 Zhuang, 2015, Inactivation of antibiotic resistance genes in municipal wastewater by chlorination, ultraviolet, and ozonation disinfection, Environ. Sci. Pollut. Res., 22, 7037, 10.1007/s11356-014-3919-z