Plasma soluble urokinase receptor levels are increased but do not distinguish primary from secondary focal segmental glomerulosclerosis

Kidney International - Tập 84 - Trang 366-372 - 2013
Jing Huang1,2,3,4, Gang Liu1,2,3,4, Yi-Miao Zhang1,2,3,4, Zhao Cui1,2,3,4, Fang Wang1,2,3,4, Xiao-Jing Liu1,2,3,4, Rong Chu1,2,3,4, Ying Chen1,2,3,4, Ming-Hui Zhao1,2,3,4
1Renal Division, Peking University First Hospital, Beijing, People’s Republic of China
2Institute of Nephrology, Peking University, Beijing, People’s Republic of China
3Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, People’s Republic of China
4Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, People’s Republic of China

Tài liệu tham khảo

Wharram, 2005, Podocyte depletion causes glomerulosclerosis: diphtheria toxin induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene, J Am Soc Nephrol, 16, 2941, 10.1681/ASN.2005010055 Kriz, 2003, The pathogenesis of ‘classic’ focal segmental glomerulosclerosis-lessons from rat models, Nephrol Dial Transplant, 18, vi39, 10.1093/ndt/gfg1064 Hickson, 2009, Kidney transplantation for primary focal segmental glomerulosclerosis: outcomes and response to therapy for recurrence, Transplantation, 87, 1232, 10.1097/TP.0b013e31819f12be Artero, 1994, Plasmapheresis reduces proteinuria and serum capacity to injure glomeruli in patients with recurrent focal glomerulosclerosis, Am J Kidney Dis, 23, 574, 10.1016/S0272-6386(12)80381-7 McCarthy, 2010, Circulating permeability factors in idiopathic nephrotic syndrome and focal segmental glomerulosclerosis, Clin J Am Soc Nephrol, 5, 2115, 10.2215/CJN.03800609 Savin, 1996, Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis, N Eng J Med, 334, 878, 10.1056/NEJM199604043341402 Wei, 2011, Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis, Nat Med, 17, 952, 10.1038/nm.2411 Korbet, 2002, Treatment of primary focal segmental glomerulosclerosis, Kidney Int, 62, 2301, 10.1046/j.1523-1755.2002.00674.x Blasi, 2002, uPAR: a versatile signalling orchestrator, Nat Rev Mol Cell Biol, 3, 932, 10.1038/nrm977 Smith, 2010, Regulation of cell signalling by uPAR, Nat Rev Mol Cell Biol, 11, 23, 10.1038/nrm2821 Maas, 2012, Serum-soluble urokinase receptor concentration in primary FSGS, Kidney Int, 81, 1043, 10.1038/ki.2012.32 Zhang, 2012, Amiloride off-target effect inhibits podocyte urokinase receptor expression and reduces proteinuria, Nephrol Dial Transplant, 27, 1746, 10.1093/ndt/gfr612 Clement, 2011, Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome, Nat Med, 17, 117, 10.1038/nm.2261 Deegens, 2008, Podocyte foot process effacement as a diagnostic tool in focal segmental glomerulosclerosis, Kidney Int, 74, 1568, 10.1038/ki.2008.413 Garin, 2009, Urinary CD80 is elevated in minimal change disease but not in focal segmental glomerulosclerosis, Kidney Int, 78, 296, 10.1038/ki.2010.143 Giannico, 2009, Dystroglycan in the diagnosis of FSGS, Clin J Am Soc Nephrol, 4, 1747, 10.2215/CJN.01510209 Sharif, 1998, Podocyte phenotypes as defined by expression and distribution of GLEPP1 in the developing glomerulus and in nephrotic glomeruli from MCD, CNF, and FSGS, Exp Nephrol, 6, 234, 10.1159/000020528 Wagrowska-Danilewicz, 2007, Synaptopodin immunoexpression in steroid-responsive and steroid-resistant minimal change disease and focal segmental glomerulosclerosis, Nefrologia, 27, 710 Worthmann, 2009, Urinary excretion of IGFBP-1 and-3 correlates with disease activity and differentiates focal segmental glomerulosclerosis and minimal change disease, Growth Factors, 28, 129, 10.3109/08977190903512594 Deegens, 2008, Pathological variants of focal segmental glomerulosclerosis in an adult Dutch population--pidemiology and outcome, Nephrol Dial Transplant, 23, 186, 10.1093/ndt/gfm523 Schwartz, 1995, Primary focal segmental glomerular sclerosis in adults: prognostic value of histologic variants, Am J Kidney Dis, 25, 845, 10.1016/0272-6386(95)90566-9 Wei, 2007, Modification of kidney barrier function by the urokinase receptor, Nat Med, 14, 55, 10.1038/nm1696 D'Agati, 2003, Pathologic classification of focal segmental glomerulosclerosis: a working proposal, Am J Kidney Dis, 43, 368, 10.1053/j.ajkd.2003.10.024 Schwartz, 2007 Yu, 2010, Tubulointerstitial lesions of patients with lupus nephritis classified by the 2003 International Society of Nephrology and Renal Pathology Society system, Kidney Int, 77, 820, 10.1038/ki.2010.13 Yamamoto, 1993, Interstitial inflammatory and chronic tubulointerstitial lesions in lupus nephritis: comparison with those in IgA nephropathy, Lupus, 2, 261, 10.1177/096120339300200114