Reduction of antigen-induced respiratory abnormalities and airway inflammation in sensitized guinea pigs by a superoxide dismutase mimetic

Rennard, 1996, Repair mechanisms in asthma, J. Allergy Clin. Immunol., 98, S278, 10.1016/S0091-6749(96)70076-3 Bast, 1991, Oxidants and antioxidants: state of the art, Am. J. Med., 91, S2, 10.1016/0002-9343(91)90278-6 Calhoun, 1992, Enhanced superoxide production by alveolar macrophages and air-space cells, airway inflammation, and alveolar macrophage density changes after segmental antigen bronchoprovocation in allergic subjects, Am. Rev. Respir. Dis., 145, 317, 10.1164/ajrccm/145.2_Pt_1.317 Wu, 2000, Eosinophils generate brominating oxidants in allergen-induced asthma, J. Clin. Invest., 105, 1455, 10.1172/JCI9702 Rahman, 1996, Induction of gamma-glutamylcysteine synthetase by cigarette smoke is associated with AP-1 in human alveolar epithelial cells, FEBS Lett., 396, 21, 10.1016/0014-5793(96)01027-7 Comhair, 1999, Increased glutathione and glutathione peroxidase in lungs of individuals with chronic beryllium disease, Am. J. Respir. Crit. Care Med., 159, 1824, 10.1164/ajrccm.159.6.9810044 Comhair, 2000, Rapid loss of superoxide dismutase activity during antigen-induced asthmatic response, Lancet, 355, 624, 10.1016/S0140-6736(99)04736-4 Page, 2001, Human mast cell and airway smooth muscle cell interactions: implications for asthma, Am. J. Physiol. Lung Cell. Mol. Physiol., 281, L1313, 10.1152/ajplung.2001.281.6.L1313 Brightling, 2002, Mast-cell infiltration of airway smooth muscle in asthma, N. Engl. J. Med., 346, 1699, 10.1056/NEJMoa012705 Rossi, 1997, Does the mast cell still have a key role in asthma?, Chest, 112, 523, 10.1378/chest.112.2.523 Bowler, 2002, Oxidative stress in airways. Is there a role for extracellular superoxide dismutase?, Am. J. Respir. Crit. Care, 166, S38, 10.1164/rccm.2206014 Bowler, 2002, Oxidative stress in allergic respiratory diseases, J. Allergy Clin. Immunol., 110, 349, 10.1067/mai.2002.126780 Barnes, 1990, Reactive oxygen species and airway inflammation, Free Radic. Biol. Med., 9, 235, 10.1016/0891-5849(90)90034-G Smith, 1997, Reduced superoxide dismutase in lung cells of patients with asthma, Free Radic. Biol. Med., 22, 1301, 10.1016/S0891-5849(96)00550-3 Beckman, 1990, Apparent hydroxyl radical production by peroxynitrite: implication for endothelial injury from nitric oxide and superoxide, Proc. Natl. Acad. Sci. USA, 87, 1620, 10.1073/pnas.87.4.1620 Yamakura, 1998, Inactivation of human manganese-superoxide dismutase by peroxynitrite is caused by exclusive nitration of tyrosine 34 to 3-nitrotyrosine, J. Biol. Chem., 273, 14085, 10.1074/jbc.273.23.14085 Macmillan–Crow, 1999, Tyrosine modifications and inactivation of active site manganese superoxide dismutase mutant (y34f) by peroxynitrite, Arch. Biochem. Biophys., 66, 82, 10.1006/abbi.1999.1202 Macmillan–Crow, 2001, Invited review: manganese superoxide dismutase in disease, Free Radic. Res., 34, 325, 10.1080/10715760100300281 Yamakura, 2001, Modification of a single tryptophan residue in human Cu,Zn-superoxide dismutase by peroxynitrite in the presence of bicarbonate, Biochim. Biophys. Acta, 1548, 38, 10.1016/S0167-4838(01)00212-6 Larsen, 2000, Mice that overexpress Cu/Zn superoxide dismutase are resistant to allergen-induced changes in airway control, Am. J. Physiol. (Lung Cell Mol. Physiol.), 279, L350, 10.1152/ajplung.2000.279.2.L350 Bani, 1997, Relaxin counteracts asthma-like reaction induced by inhaled antigen in sensitised guinea pigs, Endocrinology, 138, 1909, 10.1210/en.138.5.1909 Xiang, 1998, Effects of airway inflammation on cough response in the guinea pig, J. Appl. Physiol., 85, 1847, 10.1152/jappl.1998.85.5.1847 Liu, 2001, Characterization of increaed cough sensitivity after antigen challenge in guinea pigs, Clin. Exp. Allergy, 31, 474, 10.1046/j.1365-2222.2001.00989.x Suzuki, 2004, Inhibition of poly(ADP-ribose) polymerase prevents allergen-induced asthma-like reaction in sensitised guinea pigs, J. Pharmacol. Exp. Ther., 311, 1241, 10.1124/jpet.104.072546 Riley, 1997, Toward the rational design of superoxide dismutase mimics: mechanistic studies for the elucidation of substituent effects on the catalysis activity of macrocyclic manganese (II) complexes, J. Am. Chem. Soc., 119, 6522, 10.1021/ja964271e Salvemini, 1999, A non-peptidyl mimic of superoxide dismutase with therapeutic activity in rats, Science, 286, 304, 10.1126/science.286.5438.304 Cuzzocrea, 2001, Protective effects of M40403, a superoxide dismutase mimetic, in a rodent model of colitis, Eur. J. Pharmacol., 432, 79, 10.1016/S0014-2999(01)01427-3 Masini, 2002, Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo, Br. J. Pharmacol., 136, 905, 10.1038/sj.bjp.0704774 Ballati, 1992, Repeated antigen challenge induced airway hyperresponsiveness to neurokinin A and vagal non-adrenergic, non-cholinergic (NANC) stimulation in guinea pigs, Life Sci., 51, L119, 10.1016/0024-3205(92)90616-W Jones, 1982, Biological activity of leukotriene sulfones on respiratory tissues, Prostaglandins, 24, 279, 10.1016/0090-6980(82)90154-X Masini, 1994, Effects of relaxin on mast cells. In vitro and in vivo studies in rats and guinea pigs, J. Clin. Invest., 94, 1974, 10.1172/JCI117549 Bucchieri, 2002, Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis, Am. J. Respir. Cell. Mol. Biol., 27, 179, 10.1165/ajrcmb.27.2.4699 Mullane, 1985, Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium, J. Pharmacol. Methods, 14, 157, 10.1016/0160-5402(85)90029-4 Aruoma, 1989, The mechanism of initiation of lipid peroxidation: evidence against a requirement for an iron (II)-iron (III) complex, Biochem. J., 258, 617, 10.1042/bj2580617 Lodovici, 2000, Levels of 8-hydroxydeoxyguanosine as a marker of DNA damage in human leukocytes, Free Radic. Biol. Med., 28, 13, 10.1016/S0891-5849(99)00194-X Beuchamp, 1971, Superoxide dismutase: improved assays and an assay applicable to acrylamide gels, Anal. Biochem., 44, 276, 10.1016/0003-2697(71)90370-8 Nishida, 2002, Changes of Cu,Zn-superoxide dismutase activity of guinea pig lung in experimental asthma, Free Radic. Res., 36, 601, 10.1080/10715760210872 Bochenek, 2004, Plasma 9alpha,11beta-PGF2, a PGD2 metabolite, as a sensitive marker of mast cell activation by allergen in bronchial asthma, Thorax, 59, 459, 10.1136/thx.2003.013573 Jarjour, 1994, Enhanced production of oxygen radicals in asthma, J. Lab. Clin. Med., 123, 131 Kroegel, 1994, Blood and bronchoalveolar eosinophils in allergic subjects after segmental antigen challenge: surface phenotype, density heterogeneity, and prostanoid production, J. Allergy Clin. Immunol., 93, 725, 10.1016/0091-6749(94)90252-6 Mannaioni, 1988, The release of histamine by free radicals, Free Radic. Biol. Med., 5, 177, 10.1016/0891-5849(88)90080-9 Wardlaw, 1988, Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity, Am. Rev. Respir. Dis., 137, 62, 10.1164/ajrccm/137.1.62 Yoshimaru, 2002, Blockade of superoxide generation prevents high-affinity immunoglobulin E receptor-mediated release of allergic mediators by rat mast cell line and human basophils, Clin. Exp. Allergy, 32, 612, 10.1046/j.0954-7894.2002.01263.x Williams, 2000, Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice, J. Exp. Med., 192, 455, 10.1084/jem.192.3.455 Beasley, 1989, Cellular events in the bronchi in mild asthma and after bronchial provocation, Am. Rev. Respir. Dis., 139, 806, 10.1164/ajrccm/139.3.806 Djukanovic, 1992, Effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma, Am. Rev. Respir. Dis., 145, 669, 10.1164/ajrccm/145.3.669 Pesci, 1993, Histochemical characteristics and degranulation of mast cells in epithelium and lamina propria of bronchial biopsies from asthmatic and normal subjects, Am. Rev. Respir. Dis., 147, 684, 10.1164/ajrccm/147.3.684 O'Sullivan, 1999, On the role of PGD2 metabolites as markers of mast cell activation in asthma, Acta Physiol. Scand. Suppl., 644, 1