Gut–liver axis: The impact of gut microbiota on non alcoholic fatty liver disease

Nutrition, Metabolism and Cardiovascular Diseases - Tập 22 - Trang 471-476 - 2012
D. Compare1, P. Coccoli1, A. Rocco1, O.M. Nardone1, S. De Maria2, M. Cartenì2, G. Nardone1
1Department of Clinical and Experimental Medicine, Gastroenterology Unit, Federico II University of Naples, Via S. Pansini 5, 80131 Naples, Italy
2Department of Experimental Medicine, Federico II University of Naples, Italy

Tài liệu tham khảo

Son, 2010, Contribution of gut bacteria to liver pathobiology, Gastroenterol Res Pract, 10.1155/2010/453563 Guarner, 2003, Gut flora in health and disease, Lancet, 361, 512, 10.1016/S0140-6736(03)12489-0 Abt, 2009, The intestinal microbiota in health and disease: the influence of microbial products on immune cell homeostasis, Curr Opin Gastroenterol, 25, 496, 10.1097/MOG.0b013e328331b6b4 Eckburg, 2005, Diversity of the human intestinal microbial flora, Science, 308, 1635, 10.1126/science.1110591 O'Hara, 2006, The gut flora as a forgotten organ, EMBO Rep, 7, 688, 10.1038/sj.embor.7400731 Neish, 2009, Microbes in gastrointestinal health and disease, Gastroenterology, 136, 65, 10.1053/j.gastro.2008.10.080 Zhang, 2001, Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity, J Clin Invest, 107, 13, 10.1172/JCI11837 Clavel, 2007, Molecular interactions between bacteria, the epithelium, and the mucosal immune system in the intestinal tract: implications for chronic inflammation, Curr Issues Intest Microbiol, 8, 25 Shanahan, 2002, The host-microbe interface within the gut, Best Pract Res Clin Gastroenterol, 16, 915, 10.1053/bega.2002.0342 Xu, 2003, Honor thy symbionts, Proc Natl Acad Sci U S A, 100, 10452, 10.1073/pnas.1734063100 Wells, 2011, Epithelial crosstalk at the microbiota-mucosal interface, Proc Natl Acad Sci U S A, 108, 4607, 10.1073/pnas.1000092107 Cani, 2009, The role of the gut microbiota in energy metabolism and metabolic disease, Curr Pharm Des, 15, 1546, 10.2174/138161209788168164 Othman, 2008, Alterations in intestinal microbial flora and human disease, Curr Opin Gastroenterol, 24, 11, 10.1097/MOG.0b013e3282f2b0d7 Nagata, 2007, Common pathogenic mechanism in development progression of liver injury caused by non-alcoholic or alcoholic steatohepatitis, J Toxicol Sci, 32, 453, 10.2131/jts.32.453 Zeuzem, 2000, Gut-liver axis, Int J Colorectal Dis, 15, 59, 10.1007/s003840050236 Han, 2002, Intestinal endotoxemia as a pathogenetic mechanism in liver failure, World J Gastroenterol, 8, 961, 10.3748/wjg.v8.i6.961 Bilzer, 2006, Role of Kupffer cells in host defense and liver disease, Liver Int, 26, 1175, 10.1111/j.1478-3231.2006.01342.x Jirillo, 2002, The role of the liver in the response to LPS: experimental and clinical findings, J Endotoxin Res, 8, 319 Bedogni, 2010, Relationship between fatty liver and glucose metabolism: a cross-sectional study in 571 obese children, Nutr Metab Cardiovasc Dis Succurro, 2011, One-hour post-load plasma glucose levels are associated with elevated liver enzymes, Nutr Metab Cardiovasc Dis, 21, 713, 10.1016/j.numecd.2011.02.002 Abete, 2011, Obesity and metabolic syndrome: potential benefit from specific nutritional components, Nutr Metab Cardiovasc Dis, 21, B1, 10.1016/j.numecd.2011.05.001 Dixon, 2001, Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese, Gastroenterology, 121, 91, 10.1053/gast.2001.25540 Law, 2010, Nonalcoholic fatty liver disease, Clin Liver Dis, 14, 591, 10.1016/j.cld.2010.07.006 Tilg, 2010, Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis, Hepatology, 52, 1836, 10.1002/hep.24001 Vanni, 2009, The gut-liver axis in nonalcoholic fatty liver disease: another pathway to insulin resistance?, Hepatology, 49, 1790, 10.1002/hep.23036 Solga, 2003, Non-alcoholic fatty liver disease: lumen-liver interactions and possible role for probiotics, J Hepatol, 38, 681, 10.1016/S0168-8278(03)00097-7 Diamant, 2011, Do nutrient-gut-microbiota interactions play a role in human obesity, insulin resistance and type 2 diabetes?, Obes Rev, 12, 272, 10.1111/j.1467-789X.2010.00797.x Thuy, 2008, Nonalcoholic fatty liver disease in humans is associated with increased plasma endotoxin and plasminogen activator inhibitor 1 concentrations and with fructose intake, J Nutr, 138, 1452, 10.1093/jn/138.8.1452 Miele, 2009, Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease, Hepatology, 49, 1877, 10.1002/hep.22848 Pappo, 1991, Polymyxin B reduces cecal flora, TNF production and hepatic steatosis during total parenteral nutrition in the rat, J Surg Res, 51, 106, 10.1016/0022-4804(91)90078-Z Drenick, 1982, Hepatic steatosis after intestinal bypass-prevention and reversal by metronidazole, irrespective of protein-calorie malnutrition, Gastroenterology, 82, 535, 10.1016/S0016-5085(82)80403-4 Abu-Shanab, 2010, The role of the gut microbiota in nonalcoholic fatty liver disease, Nat Rev Gastroenterol Hepatol, 7, 691, 10.1038/nrgastro.2010.172 Turnbaugh, 2006, An obesity-associated gut microbiome with increased capacity for energy harvest, Nature, 444, 1027, 10.1038/nature05414 Bäckhed, 2004, The gut microbiota as an environmental factor that regulates fat storage, Proc Natl Acad Sci U S A, 101, 15718, 10.1073/pnas.0407076101 Ley, 2006, Microbial ecology: human gut microbes associated with obesity, Nature, 444, 1022, 10.1038/4441022a Spencer, 2011, Association between composition of the human gastrointestinal microbiome and development of fatty liver with choline deficiency, Gastroenterology, 140, 976, 10.1053/j.gastro.2010.11.049 Szabo, 2005, Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: the role of toll-like receptors 2 and 4, Alcohol Clin Exp Res, 29, 140S, 10.1097/01.alc.0000189287.83544.33 Miura, 2010, Role of toll-like receptors and their downstream molecules in the development of nonalcoholic fatty liver disease, Gastroenterol Res Pract, 2010, 362847, 10.1155/2010/362847 Rivera, 2007, Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis, J Hepatol, 47, 571, 10.1016/j.jhep.2007.04.019 Rivera, 2010, Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis, BMC Gastroenterol, 10, 52, 10.1186/1471-230X-10-52 Miura, 2010, Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice, Gastroenterology, 139, 323, 10.1053/j.gastro.2010.03.052 Minocha, 2009, Probiotics for preventive health, Nutr Clin Pract, 24, 227, 10.1177/0884533608331177 Nardone, 2004, Probiotics: a potential target for the prevention and treatment of steatohepatitis, J Clin Gastroenterol, 38, S121, 10.1097/01.mcg.0000128934.53920.1d Li, 2003, Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease, Hepatology, 37, 343, 10.1053/jhep.2003.50048 Ewaschuk, 2007, Probiotic bacteria prevent hepatic damage and maintain colonic barrier function in a mouse model of sepsis, Hepatology, 46, 841, 10.1002/hep.21750 Ma, 2008, Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells, J Hepatol, 49, 821, 10.1016/j.jhep.2008.05.025 Velayudham, 2009, VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice, Hepatology, 49, 989, 10.1002/hep.22711 Nardone, 2010, Protective effects of Lactobacillus paracasei F19 in a rat model of oxidative and metabolic hepatic injury, Am J Physiol Gastrointest Liver Physiol, 299, G669, 10.1152/ajpgi.00188.2010 Aller, 2011, Effect of a probiotic on liver aminotransferases in nonalcoholic fatty liver disease patients: a double blind randomized clinical trial, Eur Rev Med Pharmacol Sci, 15, 1090 Parnell, 2011, The potential role of prebiotic fibre for treatment and management of non-alcoholic fatty liver disease and associated obesity and insulin resistance, Liver Int