Efficacy of Amoxicillin Treatment in Preventing Postoperative Complications in Patients Undergoing Third Molar Surgery: A Prospective, Randomized, Double-Blind Controlled Study

Peterson, 1990, Antibiotic prophylaxis against wound infections in oral and maxillofacial surgery, J Oral Maxillofac Surg, 48, 617, 10.1016/S0278-2391(10)80477-X Bystedt, 1981, A comparison of the effect of phenoximethylpenicillin and azidocillin on postoperative complications after surgical removal of impacted mandibular third molars, Swed Dent J, 5, 225 Yoshii, 2001, Incidence of deep fascial space infection after surgical removal of the mandibular third molars, J Infect Chemother, 7, 55, 10.1007/s101560170036 Goldberg, 1985, Complications after mandibular third molar surgery: A statistical analysis of 500 consecutive procedures in private practice, J Am Dent Assoc, 111, 277, 10.14219/jada.archive.1985.0098 Osborn, 1985, A prospective study of complications related to mandibular third molar surgery, J Oral Maxillofac Surg, 43, 767, 10.1016/0278-2391(85)90331-3 Al-Asfour, 2009, Postoperative infection after surgical removal of impacted mandibular third molars: An analysis of 110 consecutive procedures, Med Princ Pract, 8, 48, 10.1159/000163046 Nordenram, 1973, Neomycin-bacitracin cones in impacted third molar sockets, Int J Oral Surg, 2, 279, 10.1016/S0300-9785(73)80023-7 Curran, 1974, An assessment of the use of prophylactic antibiotics in third molar surgery, Int J Oral Surg, 3, 1, 10.1016/S0300-9785(74)80030-X Mitchell, 1986, A controlled clinical trial of prophylactic tinidazole for chemoprophylaxis in third molar surgery, Br Dent J, 160, 284, 10.1038/sj.bdj.4805844 Happonen, 1990, Prophylactic use of phenoxymethylpenicillin and tinidazole in mandibular third molar surgery, a comparative placebo controlled clinical trial, Br J Oral Maxillofac Surg, 28, 12, 10.1016/0266-4356(90)90003-4 Sands, 1993, Third molar surgery: Current concepts and controversies, Oral Health, 83, 19 Hochwald-Da, 1983, Modified distolingual splitting technique for removal of impacted mandibular third molars: Incidence of postoperative sequelae, Oral Surg Oral Med Oral Pathol, 56, 9, 10.1016/0030-4220(83)90047-6 Lacasa, 2007, Prophylaxis versus pre-emptive treatment for infective and inflammatory complications of surgical third molar removal: A randomized, double-blind, placebo-controlled, clinical trial with sustained release amoxicillin/clavulanic acid (1000/62.5 mg), Int J Oral Maxillofac Surg, 36, 321, 10.1016/j.ijom.2006.11.007 Colorado-Bonnin, 2006, Quality of life following lower third molar removal, Int J Oral Maxillofac Surg, 35, 343, 10.1016/j.ijom.2005.08.008 Piecuch, 1995, Prophylactic antibiotics for third molar surgery: A supportive opinion, J Oral Maxillofac Surg, 53, 53, 10.1016/0278-2391(95)90502-2 Palmer, 2000, A study of prophylactic antibiotic prescribing in National Health Service general dental practice in England, Br Dent J, 189, 43, 10.1038/sj.bdj.4800597 Zadik, 2008, Clinical decision making in restorative dentistry, endodontics, and antibiotic prescription, Dent J, 72, 81 Kaziro, 1984, Metronidazole (Flagyl) and Arnica montana in the prevention of post-surgical complications, a comparative placebo controlled clinical trial, Br J Oral Maxillofac Surg, 22, 42, 10.1016/0266-4356(84)90007-X Lloyd, 1994, Metronidazole: Two, or three times daily—A comparative controlled clinical trial of the efficacy of two different dosing schedules of metronidazole for chemoprophylaxis following third molar surgery, Br J Oral Maxillofac Surg, 32, 165, 10.1016/0266-4356(94)90102-3 Kaczmarzyk, 2007, Single-dose and multi-dose clindamycin therapy fails to demonstrate efficacy in preventing infectious and inflammatory complications in third molar surgery, Int J Oral Maxillofac Surg, 36, 417, 10.1016/j.ijom.2006.12.003 Limeres, 2009, Patients' perception of recovery after third molar surgery following postoperative treatment with moxifloxacin versus amoxicillin and clavulanic acid: A randomized, double-blind, controlled study, J Oral Maxillofac Surg, 67, 286, 10.1016/j.joms.2008.06.061 Bulut, 2001, The value of routine antibiotic prophylaxis in mandibular third molar surgery: Acute-phase protein levels as indicator of infection, J Oral Sci, 43, 117, 10.2334/josnusd.43.117 Monaco, 1999, Antibiotic therapy in impacted third molar surgery, Eur J Oral Sci, 107, 437, 10.1046/j.0909-8836.1999.eos107604.x Delilbasi, 2002, Effects of 0.2% chlorhexidine gluconate and amoxicillin plus clavulanic acid on the prevention of alveolar osteitis following mandibular third molar extractions, Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 94, 301, 10.1067/moe.2002.125200 Arteagoitia, 2005, Efficacy of amoxicillin/clavulanic acid in preventing infectious and inflammatory complications following impacted mandibular third molar extraction, Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 100, E11, 10.1016/j.tripleo.2005.03.025 Ren, 2007, Effectiveness of antibiotic prophylaxis in third molar surgery: A meta-analysis of randomized controlled clinical trials, J Oral Maxillofac Surg, 65, 1909, 10.1016/j.joms.2007.03.004 Halpern, 2007, Does prophylactic administration of systemic antibiotics prevent postoperative inflammatory complications after third molar surgery?, J Oral Maxillofac Surg, 65, 177, 10.1016/j.joms.2006.10.016 Monaco, 2009, Evaluation of antibiotic prophylaxis in reducing postoperative infection after mandibular third molar extraction in young patients, J Oral Maxillofac Surg, 67, 1467, 10.1016/j.joms.2008.12.066 Ataoğlu, 2008, Routine antibiotic prophylaxis is not necessary during operations to remove third molars, Br J Oral Maxillofac Surg, 46, 133, 10.1016/j.bjoms.2006.11.005 Lindeboom, 2008, The controversy continues!!, Int J Oral Maxillofac Surg, 37, 199, 10.1016/j.ijom.2007.07.027 Kaczmarzyk, 2009, Abuse of antibiotic prophylaxis in third molar surgeries, J Oral Maxillofac Surg, 67, 2551, 10.1016/j.joms.2009.06.020 2007 Lombardía-García, 1987, Antimicrobial prophylaxis in surgery of the third molar: Analytic study of postoperative complications, Arch Odonto Estomatol, 3, 130 Graziani, 2005, Clinical evaluation of piroxicam-FDDF and azithromycin in the prevention of complications associated with impacted lower third molar extraction, Pharmacol Res, 52, 485, 10.1016/j.phrs.2005.07.009 Ritzau, 1992, Does metronidazole prevent alveolitis sicca dolorosa?, Int J Oral Maxillofac Surg, 21, 299, 10.1016/S0901-5027(05)80743-X Grossi, 2007, Assessing postoperative discomfort after third molar surgery: A prospective study, J Oral Maxillofac Surg, 65, 901, 10.1016/j.joms.2005.12.046 Siddiqi, 2010, Antibiotic prophylaxis in third molar surgery: A randomized double-blind placebo controlled clinical trial using split-mouth technique, Int J Oral Maxillofac Surg, 39, 107, 10.1016/j.ijom.2009.12.014 Poeschl, 2004, Postoperative prophylactic antibiotic treatment in third molar surgery—A necessity?, J Oral Maxillofac Surg, 62, 3, 10.1016/j.joms.2003.05.004 Sancho-Puchades, 2009, Analysis of the antibiotic prophylaxis prescribed by Spanish Oral Surgeons, Med Oral Patol Oral Cir Bucal, 14, e533, 10.4317/medoral.14.e533 Pallasch, 1996, Antibiotic prophylaxis and the medically compromised patient, Periodontol 2000, 10, 107, 10.1111/j.1600-0757.1996.tb00071.x