Limitation of TREC-based newborn screening for ZAP70 Severe Combined Immunodeficiency

Clinical Immunology - Tập 153 Số 1 - Trang 209-210 - 2014
Serge Grazioli1, Mary Bennett1, Kyla J. Hildebrand2, Hilary Vallance3, Stuart E. Turvey2, Anne Junker4
1Pediatric Intensive Care Unit, Department of Pediatrics, British Columbia Children's Hospital, University of British Columbia, Vancouver, BC, Canada.
2Division of Clinical Immunology and Allergy, Department of Pediatrics, British Columbia Children's Hospital, Child & Family Research Institute, University of British Columbia, Vancouver, BC, Canada.
3Department of Pathology , British Columbia Children’s Hospital , Vancouver , BC , Canada
4Division of Clinical Immunology and Allergy, Department of Pediatrics, British Columbia Children's Hospital, Child & Family Research Institute, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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Hazenberg, 2000, Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection, Nat. Med., 6, 1036, 10.1038/79549

Chen, 2005, Prediction of T-cell reconstitution by assessment of T-cell receptor excision circle before allogeneic hematopoietic stem cell transplantation in pediatric patients, Blood, 105, 886, 10.1182/blood-2004-04-1405

Chase, 2011, Newborn screening for SCID: three years of experience, Ann. N. Y. Acad. Sci., 1238, 99, 10.1111/j.1749-6632.2011.06241.x

Kwan, 2013, Newborn screening for severe combined immunodeficiency and T-cell lymphopenia in California: results of the first 2years, J. Allergy Clin. Immunol., 132, 140, 10.1016/j.jaci.2013.04.024

Verbsky, 2012, The Wisconsin approach to newborn screening for severe combined immunodeficiency, J. Allergy Clin. Immunol., 129, 622, 10.1016/j.jaci.2011.12.004

Hale, 2010, Identification of an infant with severe combined immunodeficiency by newborn screening, J. Allergy Clin. Immunol., 126, 1073, 10.1016/j.jaci.2010.08.043

Roifman, 2012, Defining combined immunodeficiency, J. Allergy Clin. Immunol., 130, 177, 10.1016/j.jaci.2012.04.029

Arpaia, 1994, Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase, Cell, 76, 947, 10.1016/0092-8674(94)90368-9

Hong-Diep Kim, 2013, Emergency treatment for zeta chain-associated protein of 70kDa (ZAP70) deficiency, J. Allergy Clin. Immunol., 131, 1233, 10.1016/j.jaci.2012.09.020