Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer

Cancer Cell - Tập 23 - Trang 316-331 - 2013
Chenfang Dong1,2, Tingting Yuan1,2, Yadi Wu3,2, Yifan Wang1,2, Teresa W.M. Fan4, Sumitra Miriyala5,2, Yiwei Lin1,2, Jun Yao6, Jian Shi1,2, Tiebang Kang7, Pawel Lorkiewicz4, Daret St Clair5,2, Mien-Chie Hung8,9, B. Mark Evers1,10,2, Binhua P. Zhou1,2
1Department of Molecular and Cellular Biochemistry, The University of Kentucky, College of Medicine, Lexington, KY 40506, USA
2Markey Cancer Center, The University of Kentucky, College of Medicine, Lexington, KY 40506, USA
3Department of Molecular and Biomedical Pharmacology, The University of Kentucky, College of Medicine, Lexington, KY 40506, USA
4Center for Regulatory and Environmental Analytical Metabolomics, Department of Chemistry and J.G. Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA
5Graduate Center for Toxicology, The University of Kentucky, College of Medicine, Lexington, KY 40506, USA
6Department of Neuro-Oncology, The University of Texas, M.D. Anderson Cancer Center, Houston, TX 77030, USA
7State Key Laboratory of Oncology in South China, Guangzhou, 510060, China
8Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA
9Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University, Taichung, Taiwan
10Department of Surgery, The University of Kentucky, College of Medicine, Lexington, KY 40506, USA

Tài liệu tham khảo

Blick, 2010, Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer, J. Mammary Gland Biol. Neoplasia, 15, 235, 10.1007/s10911-010-9175-z Bowerman, 2005, Cell biology. Oxidative stress and cancer: a beta-catenin convergence, Science, 308, 1119, 10.1126/science.1113356 Chatterjee, 2011, Mitochondrial subversion in cancer, Cancer Prev. Res. (Phila.), 4, 638, 10.1158/1940-6207.CAPR-10-0326 Chen, 2011, Promoter hypermethylation mediated downregulation of FBP1 in human hepatocellular carcinoma and colon cancer, PLoS ONE, 6, e25564, 10.1371/journal.pone.0025564 Christofk, 2008, The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth, Nature, 452, 230, 10.1038/nature06734 Crabtree, 1929, Observations on the carbohydrate metabolism of tumours, Biochem. J., 23, 536, 10.1042/bj0230536 Dang, 2008, The interplay between MYC and HIF in cancer, Nat. Rev. Cancer, 8, 51, 10.1038/nrc2274 Dhasarathy, 2011, The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer, PLoS ONE, 6, e26514, 10.1371/journal.pone.0026514 Diehn, 2009, Association of reactive oxygen species levels and radioresistance in cancer stem cells, Nature, 458, 780, 10.1038/nature07733 DiMeo, 2009, A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer, Cancer Res., 69, 5364, 10.1158/0008-5472.CAN-08-4135 Dong, 2012, G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer, J. Clin. Invest., 122, 1469, 10.1172/JCI57349 Elstrom, 2004, Akt stimulates aerobic glycolysis in cancer cells, Cancer Res., 64, 3892, 10.1158/0008-5472.CAN-03-2904 Emery, 1988, Investigation of inborn errors of metabolism in unexpected infant deaths, Lancet, 2, 29, 10.1016/S0140-6736(88)92955-8 Essers, 2005, Functional interaction between beta-catenin and FOXO in oxidative stress signaling, Science, 308, 1181, 10.1126/science.1109083 Facucho-Oliveira, 2009, The relationship between pluripotency and mitochondrial DNA proliferation during early embryo development and embryonic stem cell differentiation, Stem Cell Rev., 5, 140, 10.1007/s12015-009-9058-0 Fan, 2009, Altered regulation of metabolic pathways in human lung cancer discerned by (13)C stable isotope-resolved metabolomics (SIRM), Mol. Cancer, 8, 41, 10.1186/1476-4598-8-41 Fan, 2010, Stable isotope-resolved metabolomic analysis of lithium effects on glial-neuronal metabolism and interactions, Metabolomics, 6, 165, 10.1007/s11306-010-0208-9 Fan, 2011, Stable isotope resolved metabolomics of lung cancer in a SCID mouse model, Metabolomics, 7, 257, 10.1007/s11306-010-0249-0 Fan, 2008, Structure-based profiling of metabolites and isotopomers by NMR, Prog. Nucl. Magn. Reson. Spectrosc., 52, 69, 10.1016/j.pnmrs.2007.03.002 Koeck, 2011, A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes, Cell Metab., 13, 80, 10.1016/j.cmet.2010.12.007 Koppenol, 2011, Otto Warburg’s contributions to current concepts of cancer metabolism, Nat. Rev. Cancer, 11, 325, 10.1038/nrc3038 Le, 2012, Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells, Cell Metab., 15, 110, 10.1016/j.cmet.2011.12.009 Li, 2006, Glucose-dependent transcriptional regulation by an evolutionarily conserved glucose-sensing module, Diabetes, 55, 1179, 10.2337/db05-0822 Liu, 2010, Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis, Oncogene, 29, 442, 10.1038/onc.2009.332 Lunt, 2011, Aerobic glycolysis: meeting the metabolic requirements of cell proliferation, Annu. Rev. Cell Dev. Biol., 27, 441, 10.1146/annurev-cellbio-092910-154237 Manolagas, 2007, Gone with the Wnts: beta-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism, Mol. Endocrinol., 21, 2605, 10.1210/me.2007-0259 Mazurek, 2005, Pyruvate kinase type M2 and its role in tumor growth and spreading, Semin. Cancer Biol., 15, 300, 10.1016/j.semcancer.2005.04.009 Metodiev, 2009, Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome, Cell Metab., 9, 386, 10.1016/j.cmet.2009.03.001 Mohyeldin, 2010, Oxygen in stem cell biology: a critical component of the stem cell niche, Cell Stem Cell, 7, 150, 10.1016/j.stem.2010.07.007 Peterson, 2010, Glucose controls nuclear accumulation, promoter binding, and transcriptional activity of the MondoA-Mlx heterodimer, Mol. Cell. Biol., 30, 2887, 10.1128/MCB.01613-09 Polyak, 2011, Heterogeneity in breast cancer, J. Clin. Invest., 121, 3786, 10.1172/JCI60534 Polyak, 2009, Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits, Nat. Rev. Cancer, 9, 265, 10.1038/nrc2620 Robey, 2009, Is Akt the “Warburg kinase”?-Akt-energy metabolism interactions and oncogenesis, Semin. Cancer Biol., 19, 25, 10.1016/j.semcancer.2008.11.010 Sinthupibulyakit, 2010, p53 Protects lung cancer cells against metabolic stress, Int. J. Oncol., 37, 1575 Thiery, 2009, Epithelial-mesenchymal transitions in development and disease, Cell, 139, 871, 10.1016/j.cell.2009.11.007 van de Vijver, 2002, A gene-expression signature as a predictor of survival in breast cancer, N. Engl. J. Med., 347, 1999, 10.1056/NEJMoa021967 van Poelje, 2006, Inhibition of fructose 1,6-bisphosphatase reduces excessive endogenous glucose production and attenuates hyperglycemia in Zucker diabetic fatty rats, Diabetes, 55, 1747, 10.2337/db05-1443 van ‘t Veer, 2002, Gene expression profiling predicts clinical outcome of breast cancer, Nature, 415, 530, 10.1038/415530a Ward, 2012, Metabolic reprogramming: a cancer hallmark even warburg did not anticipate, Cancer Cell, 21, 297, 10.1016/j.ccr.2012.02.014 Zeilstra, 2008, Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis, Cancer Res., 68, 3655, 10.1158/0008-5472.CAN-07-2940
Thông tin
Thông tin xuất bản

Cancer Cell

Tập 23

316-331

Thông tin tác giả