Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis

Aaker, 2010, Interaction of MTG family proteins with NEUROG2 and ASCL1 in the developing nervous system, Neurosci. Lett., 474, 46, 10.1016/j.neulet.2010.03.004 Alvarez-Rodríguez, 2009, Expression of the proneural gene encoding Mash1 suppresses MYCN mitotic activity, J. Cell Sci., 122, 595, 10.1242/jcs.037556 Bellefroid, 1996, X-MyT1, a Xenopus C2HC-type zinc finger protein with a regulatory function in neuronal differentiation, Cell, 87, 1191, 10.1016/S0092-8674(00)81815-2 Bergstrom, 2002, Promoter-specific regulation of MyoD binding and signal transduction cooperate to pattern gene expression, Mol. Cell, 9, 587, 10.1016/S1097-2765(02)00481-1 Berninger, 2007, Functional properties of neurons derived from in vitro reprogrammed postnatal astroglia, The Journal of neuroscience,, 27, 8654, 10.1523/JNEUROSCI.1615-07.2007 Berninger, 2007, Directing neurotransmitter identity of neurones derived from expanded adult neural stem cells, Eur. J. Neurosci., 25, 2581, 10.1111/j.1460-9568.2007.05509.x Bertrand, 2002, Proneural genes and the specification of neural cell types, Nat. Rev. Neurosci., 3, 517, 10.1038/nrn874 Borromeo, 2014, A transcription factor network specifying inhibitory versus excitatory neurons in the dorsal spinal cord, Development, 141, 2803, 10.1242/dev.105866 Boyle, 2008, High-resolution mapping and characterization of open chromatin across the genome, Cell, 132, 311, 10.1016/j.cell.2007.12.014 Burk, 1991, Estrogen-dependent alterations in differentiation state of myeloid cells caused by a v-myb/estrogen receptor fusion protein, EMBO J., 10, 3713, 10.1002/j.1460-2075.1991.tb04939.x Casarosa, 1999, Mash1 regulates neurogenesis in the ventral telencephalon, Development, 126, 525, 10.1242/dev.126.3.525 Castro, 2006, Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif, Dev. Cell, 11, 831, 10.1016/j.devcel.2006.10.006 Castro, 2011, A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets, Genes Dev., 25, 930, 10.1101/gad.627811 Conti, 2005, Niche-independent symmetrical self-renewal of a mammalian tissue stem cell, PLoS Biol., 3, e283, 10.1371/journal.pbio.0030283 Ernst, 2012, ChromHMM: automating chromatin-state discovery and characterization, Nat. Methods, 9, 215, 10.1038/nmeth.1906 Forgacs, 2004, Role of the cytoskeleton in signaling networks, J. Cell Sci., 117, 2769, 10.1242/jcs.01122 Geoffroy, 2009, Engineering of dominant active basic helix-loop-helix proteins that are resistant to negative regulation by postnatal central nervous system antineurogenic cues, Stem Cells, 27, 847, 10.1002/stem.17 Gratton, 2003, Hes6 promotes cortical neurogenesis and inhibits Hes1 transcription repression activity by multiple mechanisms, Mol. Cell. Biol., 23, 6922, 10.1128/MCB.23.19.6922-6935.2003 Imayoshi, 2013, Oscillatory control of factors determining multipotency and fate in mouse neural progenitors, Science, 342, 1203, 10.1126/science.1242366 Kaltezioti, 2010, Prox1 regulates the notch1-mediated inhibition of neurogenesis, PLoS Biol., 8, e1000565, 10.1371/journal.pbio.1000565 Karow, 2012, Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells, Cell Stem Cell, 11, 471, 10.1016/j.stem.2012.07.007 Kriegstein, 2009, The glial nature of embryonic and adult neural stem cells, Annu. Rev. Neurosci., 32, 149, 10.1146/annurev.neuro.051508.135600 Langmead, 2009, Ultrafast and memory-efficient alignment of short DNA sequences to the human genome, Genome Biol., 10, R25, 10.1186/gb-2009-10-3-r25 Littlewood, 1995, A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins, Nucleic Acids Res., 23, 1686, 10.1093/nar/23.10.1686 Martínez-Cerdeño, 2010, Embryonic MGE precursor cells grafted into adult rat striatum integrate and ameliorate motor symptoms in 6-OHDA-lesioned rats, Cell Stem Cell, 6, 238, 10.1016/j.stem.2010.01.004 Natarajan, 2012, Predicting cell-type-specific gene expression from regions of open chromatin, Genome Res., 22, 1711, 10.1101/gr.135129.111 Ohsawa, 2005, Mash1 and Math3 are required for development of branchiomotor neurons and maintenance of neural progenitors, J. Neurosci., 25, 5857, 10.1523/JNEUROSCI.4621-04.2005 Park, 2009, ChIP-seq: advantages and challenges of a maturing technology, Nat. Rev. Genet., 10, 669, 10.1038/nrg2641 Piper, 2013, Wellington: a novel method for the accurate identification of digital genomic footprints from DNase-seq data, Nucleic Acids Res., 41, e201, 10.1093/nar/gkt850 Pollard, 2006, Adherent neural stem (NS) cells from fetal and adult forebrain, Cereb. Cortex, 16, i112, 10.1093/cercor/bhj167 Rheinbay, 2013, An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma, Cell Rep., 3, 1567, 10.1016/j.celrep.2013.04.021 Roemer, 1993, Modulation of cell proliferation and gene expression by a p53-estrogen receptor hybrid protein, Proc. Natl. Acad. Sci. USA, 90, 9252, 10.1073/pnas.90.20.9252 Ruzinova, 2003, Id proteins in development, cell cycle and cancer, Trends Cell Biol., 13, 410, 10.1016/S0962-8924(03)00147-8 Song, 2010, DNase-seq: a high-resolution technique for mapping active gene regulatory elements across the genome from mammalian cells, Cold Spring Harbor Protoc., 2010, 10.1101/pdb.prot5384 Song, 2011, Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity, Genome Res., 21, 1757, 10.1101/gr.121541.111 Thurman, 2012, The accessible chromatin landscape of the human genome, Nature, 489, 75, 10.1038/nature11232 Vasconcelos, 2014, Transcriptional control of vertebrate neurogenesis by the proneural factor Ascl1, Front. Cell. Neurosci., 8, 412, 10.3389/fncel.2014.00412 Vierbuchen, 2010, Direct conversion of fibroblasts to functional neurons by defined factors, Nature, 463, 1035, 10.1038/nature08797 Wapinski, 2013, Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons, Cell, 155, 621, 10.1016/j.cell.2013.09.028 Wilkinson, 2013, Proneural genes in neocortical development, Neuroscience, 253, 256, 10.1016/j.neuroscience.2013.08.029 Zaret, 2011, Pioneer transcription factors: establishing competence for gene expression, Genes Dev., 25, 2227, 10.1101/gad.176826.111 Zhang, 2008, Model-based analysis of ChIP-Seq (MACS), Genome Biol., 9, R137, 10.1186/gb-2008-9-9-r137