The role of IL-6 in inhibition of lymphocyte apoptosis by mesenchymal stem cells

Biochemical and Biophysical Research Communications - Tập 361 - Trang 745-750 - 2007
Guangwu Xu1, Yingyu Zhang1, Liying Zhang1, Guangwen Ren1, Yufang Shi1
1Department of Molecular Genetics, Microbiology and Immunology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, 661 Hoes Lane, Piscataway, NJ 08854, USA

Tài liệu tham khảo

Uccelli, 2007, Mesenchymal stem cells: a new strategy for immunosuppression?, Trends in Immunology, 28, 219, 10.1016/j.it.2007.03.001 Bartholomew, 2002, Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo, Experimental Hematology, 30, 42, 10.1016/S0301-472X(01)00769-X Rasmusson, 2006, Immune modulation by mesenchymal stem cells, Experimental Cell Research, 312, 2169, 10.1016/j.yexcr.2006.03.019 Le Blanc, 2005, Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation, Biology of Blood and Marrow Transplantation, 11, 321, 10.1016/j.bbmt.2005.01.005 Uccelli, 2006, Stem cells in inflammatory demyelinating disorders: a dual role for immunosuppression and neuroprotection, Expert Opinion on Biological Therapy, 6, 17, 10.1517/14712598.6.1.17 Ringden, 2006, Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease, Transplantation, 81, 1390, 10.1097/01.tp.0000214462.63943.14 Le Blanc, 2004, Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells, Lancet, 363, 1439, 10.1016/S0140-6736(04)16104-7 Welch, 1990, Bone marrow stromal cells and interleukin-7 induce coordinate expression of the BP-1/6C3 antigen and pre-B cell growth, International Immunology, 2, 697, 10.1093/intimm/2.8.697 Dorshkind, 1992, Regulation of B cell differentiation by bone marrow stromal cells, International Journal of Cell Cloning, 10, 12, 10.1002/stem.5530100104 Ame-Thomas, 2007, Human mesenchymal stem cells isolated from bone marrow and lymphoid organs support tumor B-cell growth: role of stromal cells in follicular lymphoma pathogenesis, Blood, 109, 693, 10.1182/blood-2006-05-020800 Ramasamy, 2007, Mesenchymal stem cells inhibit proliferation and apoptosis of tumor cells: impact on in vivo tumor growth, Leukemia, 21, 304, 10.1038/sj.leu.2404489 Zhu, 2006, Mesenchymal stem cells derived from bone marrow favor tumor cell growth in vivo, Experimental and molecular pathology, 80, 267, 10.1016/j.yexmp.2005.07.004 Siggs, 2006, The why and how of thymocyte negative selection, Current Opinion in Immunology, 18, 175, 10.1016/j.coi.2006.01.001 Green, 1992, Activation-induced apoptosis in lymphoid systems, Seminars in Immunology, 4, 379 Williams, 2007, Effector and memory CTL differentiation, Annual Review of Immunology, 25, 171, 10.1146/annurev.immunol.25.022106.141548 Badovinac, 2006, Programming, demarcating, and manipulating CD8+ T-cell memory, Immunological Reviews, 211, 67, 10.1111/j.0105-2896.2006.00384.x Xu, 2007, Immunosuppressive properties of cloned bone marrow mesenchymal stem cells, Cell Research, 17, 240, 10.1038/cr.2007.4 Wang, 2002, A simplified protocol for apoptosis assay by DNA content analysis, BioTechniques, Suppl., 88, 10.2144/Oct0210 Zubiaga, 1992, IL-4 and IL-2 selectively rescue Th cell subsets from glucocorticoid-induced apoptosis, Journal of Immunology, 149, 107, 10.4049/jimmunol.149.1.107 Mor, 1996, IL-2 rescues antigen-specific T cells from radiation or dexamethasone-induced apoptosis. Correlation with induction of Bcl-2, Journal of Immunology, 156, 515, 10.4049/jimmunol.156.2.515 Pajusto, 2004, Human in vivo-activated CD45R0(+) CD4(+) T cells are susceptible to spontaneous apoptosis that can be inhibited by the chemokine CXCL12 and IL-2, -6, -7, and -15, European Journal of Immunology, 34, 2771, 10.1002/eji.200324761 Zamorano, 2001, NF-kappa B activation plays an important role in the IL-4-induced protection from apoptosis, International Immunology, 13, 1479, 10.1093/intimm/13.12.1479 Su, 1999, Inhibition of B cell receptor-mediated apoptosis by IFN, Journal of Immunology, 162, 6317, 10.4049/jimmunol.162.11.6317 Scheel-Toellner, 1999, Inhibition of T cell apoptosis by IFN-beta rapidly reverses nuclear translocation of protein kinase C-delta, European Journal of Immunology, 29, 2603, 10.1002/(SICI)1521-4141(199908)29:08<2603::AID-IMMU2603>3.0.CO;2-L Pilling, 1999, Interferon-beta mediates stromal cell rescue of T cells from apoptosis, European Journal of Immunology, 29, 1041, 10.1002/(SICI)1521-4141(199903)29:03<1041::AID-IMMU1041>3.0.CO;2-# Chang, 2001, Human tenon’s fibroblast-produced ifnbeta and the prevention of t-cell apoptosis, Investigative Ophthalmology & Visual Science, 42, 1531 Curnow, 2004, Inhibition of T cell apoptosis in the aqueous humor of patients with uveitis by IL-6/soluble IL-6 receptor trans-signaling, Journal of Immunology, 173, 5290, 10.4049/jimmunol.173.8.5290 Teague, 1997, IL-6 rescues resting mouse T cells from apoptosis, Journal of Immunology, 158, 5791, 10.4049/jimmunol.158.12.5791 Ito, 2002, Anti-IL-6 receptor monoclonal antibody inhibits leukocyte recruitment and promotes T-cell apoptosis in a murine model of Crohn’s disease, Journal of Gastroenterology, 37, 56, 10.1007/BF03326415 Mudter, 2002, A new model of chronic colitis in SCID mice induced by adoptive transfer of CD62L+ CD4+ T cells: insights into the regulatory role of interleukin-6 on apoptosis, Pathobiology, 70, 170, 10.1159/000068150 Kurita-Ochiai, 2002, Human gingival fibroblasts rescue butyric acid-induced T-cell apoptosis, Infection and Immunity, 70, 2361, 10.1128/IAI.70.5.2361-2367.2002 Atreya, 2000, Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo, Nature Medicine, 6, 583, 10.1038/75068 Benvenuto, 2007, Human mesenchymal stem cells promote survival of T cells in a quiescent state, Stem Cells, 25, 1753, 10.1634/stemcells.2007-0068