The labdane diterpene sclareol (labd-14-ene-8, 13-diol) induces apoptosis in human tumor cell lines and suppression of tumor growth in vivo via a p53-independent mechanism of action

European Journal of Pharmacology - Tập 666 - Trang 173-182 - 2011
Louisa G. Mahaira1, Chrisiida Tsimplouli1, Nikos Sakellaridis2, Konstantinos Alevizopoulos3, Costas Demetzos4, Zhiyong Han5, Panayotis Pantazis1, Konstantinos Dimas1,2
1Division of Pharmacology-Pharmacotechnology, Foundation for Biomedical Research, Academy of Athens, Athens, Greece
2Department of Pharmacology, School of Medicine, University of Thessaly, Larisa, Greece
3Medexis SA Kryoneri, Attiki, Greece
4School of Pharmacy, Department of Pharmaceutical Technology, University of Athens, Greece
5Department of Preclinical Sciences, New York College of Podiatric Medicine, 53 East 124 Street, New York, NY 10035, USA

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