The THYCOVIT (Thyroid Surgery during COVID-19 pandemic in Italy) study: results from a nationwide, multicentric, case-controlled study

Updates in Surgery - Tập 73 - Trang 1467-1475 - 2021
Fabio Medas1, Gian Luca Ansaldo2, Nicola Avenia3, Giancarlo Basili4, Marco Boniardi5, Marco Bononi6, Aldo Bove7, Paolo Carcoforo8, Andrea Casaril9, Giuseppe Cavallaro6, Maria Grazia Chiofalo10, Giovanni Conzo11, Loredana De Pasquale12, Paolo Del Rio13, Gianlorenzo Dionigi14, Chiara Dobrinja15, Giovanni Docimo16, Giuseppa Graceffa17, Maurizio Iacobone18, Nadia Innaro19, Celestino Pio Lombardi20, Nicola Palestini21, Francesco Pedicini22, Giuliano Perigli23, Angela Pezzolla24, Gregorio Scerrino25, Stefano Spiezia26, Mario Testini27, Pietro Giorgio Calò1
1Department of Surgical Sciences, University of Cagliari, Cagliari, Italy
2Endocrine Surgery Unit, Ospedale Policlinico San Martino, Genoa, Italy
3General Surgery and Surgical Specialties Unit, Medical School, S. Maria University Hospital Terni and University of Perugia, Terni, Italy
4General Surgery Department, Endocrine Surgery Unit, Azienda USL Toscana Nord-Ovest, Pontedera, Italy
5Endocrine Surgery Unit, Department of Oncological-Mininvasive Surgery, Niguarda Hospital-Milan, Milan, Italy
6Pietro Valdoni, Department of Surgery, Sapienza University of Rome, Rome, Italy
7Department of Medicine, Dentistry and Biotechnology, University ``G. D’Annunzio’’, Chieti, Italy
8Department of Surgery, Unit of General Surgery, University Hospital of Ferrara and University of Ferrara, Ferrara, Italy
9Endocrine Surgery Unit, Pederzoli Hospital, Verona, Italy
10Thyroid Surgery Unit, Int Irccs Fondazione Pascale, Napoli, Italy
11Division of General and Oncologic Surgery, Department of Traslational Medical Sciences, University of Campania ``Luigi Vanvitelli’’, Naples, Italy
12Endocrine Surgery, ASST Santi Paolo E Carlo University of Milan, Milan, Italy
13General Surgery Unit, Parma University Hospital, Parma, Italy
14Division for Minimally Invasive and Endocrine Surgery, University of Messina, Messina, Italy
15Department of Medicine, Surgery and Health Sciences, Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI), Trieste, Italy
16Division of Thyroid Surgery, Department of Medical and Advanced Surgical Sciences, University of Campania ``Luigi Vanvitelli’’, Naples, Italy
17Department of Surgical Oncological and Stomatological Sciences, University of Palermo, Palermo, Italy
18Endocrine Surgery Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy
19Unit of Endocrine Surgery, A.O.U. Mater Domini, Catanzaro, Italy
20Division of Endocrine Surgery, Department of Gastroenterologic, Endocrine-Metabolic and Nephro-Urologic Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
21Head and Neck Oncological Surgery, Candiolo Cancer Institute, Candiolo, Italy
22Thyroid Endocrine Surgery, Sant’Eugenio Hospital, Rome, Italy
23Endocrine Surgery Unit, University of Florence, Florence, Italy
24Division of Videolaparoscopic Surgery, Department of Emergency and Organ Transplantation, University of Bari ``A.Moro’’, Bari, Italy
25Department of Surgical Oncology and Oral Sciences, Unit of General and Emergency Surgery, University of Palermo, Palermo, Italy
26Endocrine & US Guided Surgery OU, Napoli, Italy
27Unit of Academic General Surgery “V. Bonomo”, Department of Biomedical Sciences and Human Oncology, University of Bari, “A. Moro”, Bari, Italy

Tóm tắt

The outbreak of the COVID-19 pandemic has led to a disruption of surgical care. The aim of this multi-centric, retrospective study was to evaluate the impact of the pandemic on surgical activity for thyroid disease among the Italian Units of Endocrine Surgery. Three phases of the pandemic were identified based on the epidemiological situation and the public measures adopted from the Italian Government (1st phase: from 9th March to 3rd May 2020; 2nd phase: from 4th May to 14th June; 3rd phase: from 15th June to 31st). The patients operated upon during these phases were compared to those who underwent surgery during the same period of the previous year. Overall, 3892 patients from 28 Italian endocrine surgical units were included in the study, 1478 (38%) operated upon during COVID-19 pandemic, and 2414 (62%) during the corresponding period of 2019. The decrease in the number of operations was by 64.8%, 44.7% and 5.1% during the three phases of COVID-19 pandemic, compared to 2019, respectively. During the first and the second phases, the surgical activity was dedicated mainly to oncological patients. No differences in post-operative complications were noted between the two periods. Oncological activity for thyroid cancer was adequately maintained during the COVID-19 pandemic.

Tài liệu tham khảo

Søreide K, Hallet J, Matthews JB et al (2020) Immediate and long-term impact of the COVID-19 pandemic on delivery of surgical services. Br J Surg. https://doi.org/10.1002/bjs.11670 Valmasoni M, Pierobon ES, Capovilla G et al (2020) Providing surgery for cancer during the COVID-19 pandemic: experience of a northern Italian referral centre. Br J Surg 107:e326–e327. https://doi.org/10.1002/bjs.11780 Spinelli A, Pellino G (2020) COVID-19 pandemic: perspectives on an unfolding crisis. Br J Surg 107:785–787. https://doi.org/10.1002/bjs.11627 Indini A, Aschele C, Cavanna L et al (2020) Reorganisation of medical oncology departments during the novel coronavirus disease-19 pandemic: a nationwide Italian survey. Eur J Cancer 132:17–23. https://doi.org/10.1016/j.ejca.2020.03.024 Di Marzo F, Sartelli M, Cennamo R et al (2020) Recommendations for general surgery activities in a pandemic scenario (SARS-CoV-2). Br J Surg 107:1104–1106. https://doi.org/10.1002/bjs.11652 Moletta L, Pierobon ES, Capovilla G et al (2020) International guidelines and recommendations for surgery during Covid-19 pandemic: a systematic review. Int J Surg 79:180–188. https://doi.org/10.1016/j.ijsu.2020.05.061 (2020) Global guidance for surgical care during the COVID-19 pandemic. BJS (British Journal of Surgery) 107:1097–1103. https://doi.org/https://doi.org/10.1002/bjs.11646 Zhang D, Fu Y, Zhou L, et al (2020) Thyroid surgery during coronavirus-19 pandemic phases I, II and III: lessons learned in China, South Korea, Iran and Italy. Journal of Endocrinological Investigation. https://doi.org/https://doi.org/10.1007/s40618-020-01407-1 Lombardi CP, Gordini L, D’Amore A et al (2020) COVID-19 pandemic: new rules of engagement in endocrine surgery. Br J Surg 107:e322. https://doi.org/10.1002/bjs.11777 Barczyński M, Konturek A, Stopa M, Nowak W (2013) Prophylactic central neck dissection for papillary thyroid cancer. BJS 100:410–418. https://doi.org/10.1002/bjs.8985 Medas F, Canu GL, Boi F, et al (2019) Predictive Factors of Recurrence in Patients with Differentiated Thyroid Carcinoma: A Retrospective Analysis on 579 Patients. Cancers (Basel) 11:. https://doi.org/https://doi.org/10.3390/cancers11091230 Mazzaferri EL (2000) Long-term outcome of patients with differentiated thyroid carcinoma: effect of therapy. Endocr Pract 6:469–476. https://doi.org/10.4158/EP.6.6.469 http://www.salute.gov.it/portale/nuovocoronavirus/homeNuovoCoronavirus.jsp. Gazzetta Ufficiale della Repubblica Italiana. Decreto del presidente del consiglio dei ministri 9 marzo 2020. GU Serie Generale n.62 del 09–03–2020. https://www.gazzettaufficiale.it/eli/id/2020/03/09/20A01558/sg. Gazzetta Ufficiale della Repubblica Italiana. Ministero dello sviluppo economico. Decreto 4 maggio 2020. GU Serie Generale n.115 del 06–05–2020. https://www.gazzettaufficiale.it/eli/id/2020/05/06/20A02526/sg. Gazzetta Ufficiale della Repubblica Italiana. Decreto del presidente del consiglio dei ministri 11 giugno 2020. GU Serie Generale n.147 del 11–06–2020. https://www.gazzettaufficiale.it/eli/id/2020/06/11/20A03194/sg. Agha R, Abdall-Razak A, Crossley E et al (2019) STROCSS 2019 guideline: strengthening the reporting of cohort studies in surgery. Int J Surg 72:156–165. https://doi.org/10.1016/j.ijsu.2019.11.002