Using genetics to predict the natural history of asthma?
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Reed, 2006, The natural history of asthma, J Allergy Clin Immunol, 118, 543, 10.1016/j.jaci.2006.06.020
Holloway, 2010, Genetics of allergic disease, J Allergy Clin Immunol, 125, S81, 10.1016/j.jaci.2009.10.071
Arshad, 2008, Dynamics of asthma and wheeze during childhood, Am J Respir Crit Care Med, 177, A709
Kurukulaaratchy, 2008, The natural history of fatal childhood asthma—a case from the Isle of Wight Birth Cohort, J Asthma, 45, 944, 10.1080/02770900802404090
Sears, 2003, A longitudinal, population-based, cohort study of childhood asthma followed to adulthood, N Engl J Med, 349, 1414, 10.1056/NEJMoa022363
Kurukulaaratchy, 2003, Characterization of wheezing phenotypes in the first 10 years of life, Clin Exp Allergy, 33, 573, 10.1046/j.1365-2222.2003.01657.x
Martinez, 1995, Asthma and wheezing in the first six years of life. The Group Health Medical Associates, N Engl J Med, 332, 133, 10.1056/NEJM199501193320301
Kurukulaaratchy, 2003, Predicting persistent disease among children who wheeze during early life, Eur Respir J, 22, 767, 10.1183/09031936.03.00005903
Kurukulaaratchy, 2004, Characterisation of atopic and non-atopic wheeze in 10 year old children, Thorax, 59, 563, 10.1136/thx.2003.010462
Illi, 2006, Perennial allergen sensitisation early in life and chronic asthma in children: a birth cohort study, Lancet, 368, 763, 10.1016/S0140-6736(06)69286-6
Taussig, 2003, Tucson Children's Respiratory Study: 1980 to present, J Allergy Clin Immunol, 111, 661, 10.1067/mai.2003.162
Raza A, Roberts G, Kurukulaaratchy R, Karmaus W, Clayton B, Matthews S, et al. Shifting trends of adolescent asthma, Isle of Wight birth cohort. Abstract #3270 presented at: the European Respiratory Society Annual Congress, Vienna, September 12-15, 2009.
Mandhane, 2005, Sex differences in factors associated with childhood- and adolescent-onset wheeze, Am J Respir Crit Care Med, 172, 45, 10.1164/rccm.200412-1738OC
Guerra, 2004, Persistence of asthma symptoms during adolescence: role of obesity and age at the onset of puberty, Am J Respir Crit Care Med, 170, 78, 10.1164/rccm.200309-1224OC
de Marco, 2004, Influence of early life exposures on incidence and remission of asthma throughout life, J Allergy Clin Immunol, 113, 845, 10.1016/j.jaci.2004.01.780
Tantisira, 2008, Airway responsiveness in mild to moderate childhood asthma: sex influences on the natural history, Am J Respir Crit Care Med, 178, 325, 10.1164/rccm.200708-1174OC
Shaaban, 2008, Rhinitis and onset of asthma: a longitudinal population-based study, Lancet, 372, 1049, 10.1016/S0140-6736(08)61446-4
Settipane, 2000, Natural history of asthma: a 23-year followup of college students, Ann Allergy Asthma Immunol, 84, 499, 10.1016/S1081-1206(10)62512-4
Jamrozik, 2009, Risk factors for adult-onset asthma: a 14-year longitudinal study, Respirology, 14, 814, 10.1111/j.1440-1843.2009.01562.x
Dykewicz, 2009, Occupational asthma: current concepts in pathogenesis, diagnosis, and management, J Allergy Clin Immunol, 123, 519, 10.1016/j.jaci.2009.01.061
Descatha, 2007, Factors associated with severity of occupational asthma with a latency period at diagnosis, Allergy, 62, 795, 10.1111/j.1398-9995.2007.01424.x
Berges-Gimeno, 2002, The natural history and clinical characteristics of aspirin-exacerbated respiratory disease, Ann Allergy Asthma Immunol, 89, 474, 10.1016/S1081-1206(10)62084-4
Robertson, 2002, Long-term outcome of childhood asthma, Med J Aust, 177, S42
de Marco, 2006, Prognostic factors of asthma severity: a 9-year international prospective cohort study, J Allergy Clin Immunol, 117, 1249, 10.1016/j.jaci.2006.03.019
Saglani, 2007, Early detection of airway wall remodeling and eosinophilic inflammation in preschool wheezers, Am J Respir Crit Care Med, 176, 858, 10.1164/rccm.200702-212OC
Jeffery, 2004, Remodeling and inflammation of bronchi in asthma and chronic obstructive pulmonary disease, Proc Am Thorac Soc, 1, 176, 10.1513/pats.200402-009MS
Morgan, 2005, Outcome of asthma and wheezing in the first 6 years of life: follow-up through adolescence, Am J Respir Crit Care Med, 172, 1253, 10.1164/rccm.200504-525OC
Covar, 2004, Progression of asthma measured by lung function in the childhood asthma management program, Am J Respir Crit Care Med, 170, 234, 10.1164/rccm.200308-1174OC
Ulrik, 1999, Outcome of asthma: longitudinal changes in lung function, Eur Respir J, 13, 904, 10.1034/j.1399-3003.1999.13d35.x
James, 2007, Clinical relevance of airway remodelling in airway diseases, Eur Respir J, 30, 134, 10.1183/09031936.00146905
ten Brinke, 2001, Factors associated with persistent airflow limitation in severe asthma, Am J Respir Crit Care Med, 164, 744, 10.1164/ajrccm.164.5.2011026
Ly, 2006, Recurrent wheeze in early childhood and asthma among children at risk for atopy, Pediatrics, 117, e1132, 10.1542/peds.2005-2271
Phelan, 2002, The Melbourne Asthma Study: 1964-1999, J Allergy Clin Immunol, 109, 189, 10.1067/mai.2002.120951
Zeiger, 1999, Relationships between duration of asthma and asthma severity among children in the Childhood Asthma Management Program (CAMP), J Allergy Clin Immunol, 103, 376, 10.1016/S0091-6749(99)70460-4
Strachan, 1996, Incidence and prognosis of asthma and wheezing illness from early childhood to age 33 in a national British cohort, BMJ, 312, 1195, 10.1136/bmj.312.7040.1195
Illi, 2004, The natural course of atopic dermatitis from birth to age 7 years and the association with asthma, J Allergy Clin Immunol, 113, 925, 10.1016/j.jaci.2004.01.778
Covar, 2010, Predictors of remitting, periodic, and persistent childhood asthma, J Allergy Clin Immunol, 125, 359, 10.1016/j.jaci.2009.10.037
Hardy, 2009, Genomewide association studies and human disease, N Engl J Med, 360, 1759, 10.1056/NEJMra0808700
Manolio, 2008, A HapMap harvest of insights into the genetics of common disease, J Clin Invest, 118, 1590, 10.1172/JCI34772
Wu, 2009, Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma, Allergy, 64, 629, 10.1111/j.1398-9995.2008.01912.x
Narayan, 2009, Clinical risk factors, DNA variants, and the development of type 2 diabetes, N Engl J Med, 360, 1361
Hirschhorn, 2009, Genomewide association studies—illuminating biologic pathways, N Engl J Med, 360, 1699, 10.1056/NEJMp0808934
Kraft, 2009, Beyond odds ratios—communicating disease risk based on genetic profiles, Nat Rev Genet, 10, 264, 10.1038/nrg2516
Klein, 2005, Complement factor H polymorphism in age-related macular degeneration, Science, 308, 385, 10.1126/science.1109557
Lettre, 2008, Autoimmune diseases: insights from genome-wide association studies, Hum Mol Genet, 17, R116, 10.1093/hmg/ddn246
Epstein, 1968, Multiple risk factors and the prediction of coronary heart disease, Bull N Y Acad Med, 44, 916
Rahman, 2008, A simple risk score identifies individuals at high risk of developing Type 2 diabetes: a prospective cohort study, Fam Pract, 25, 191, 10.1093/fampra/cmn024
Hippisley-Cox, 2008, Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2, BMJ, 336, 1475, 10.1136/bmj.39609.449676.25
Janssens, 2006, Predictive testing for complex diseases using multiple genes: fact or fiction?, Genet Med, 8, 395, 10.1097/01.gim.0000229689.18263.f4
Kraft, 2009, Genetic risk prediction—are we there yet?, N Engl J Med, 360, 1701, 10.1056/NEJMp0810107
Zheng, 2008, Cumulative association of five genetic variants with prostate cancer, N Engl J Med, 358, 910, 10.1056/NEJMoa075819
Talmud, 2010, Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study, BMJ, 340, b4838, 10.1136/bmj.b4838
Wacholder, 2010, Performance of common genetic variants in breast-cancer risk models, N Engl J Med, 362, 986, 10.1056/NEJMoa0907727
Lyssenko, 2008, Clinical risk factors, DNA variants, and the development of type 2 diabetes, N Engl J Med, 359, 2220, 10.1056/NEJMoa0801869
Meigs, 2008, Genotype score in addition to common risk factors for prediction of type 2 diabetes, N Engl J Med, 359, 2208, 10.1056/NEJMoa0804742
Wray, 2010, The genetic interpretation of area under the ROC curve in genomic profiling, PLoS Genet, 6, e1000864, 10.1371/journal.pgen.1000864
Weiss, 2010, What genes tell us about the pathogenesis of asthma and chronic obstructive pulmonary disease, Am J Respir Crit Care Med, 181, 1170, 10.1164/rccm.201001-0069PP
Holloway, 2008, Interpatient variability in rates of asthma progression: can genetics provide an answer?, J Allergy Clin Immunol, 121, 573, 10.1016/j.jaci.2008.01.007
Katsanis, 2008, Public health. A case study of personalized medicine, Science, 320, 53, 10.1126/science.1156604
Hayashi, 1995, Prevalence of and risk factors for allergic diseases—comparison of two cities in Japan, Ann Allergy, 75, 525
Jenkins, 1997, Regressive logistic modeling of familial aggregation for asthma in 7,394 population-based nuclear families, Genet Epidemiol, 14, 317, 10.1002/(SICI)1098-2272(1997)14:3<317::AID-GEPI9>3.0.CO;2-1
Bazaral, 1971, IgE levels in normal infants and mothers and an inheritance hypothesis, J Immunol, 107, 794, 10.4049/jimmunol.107.3.794
Hopp, 1984, Genetic analysis of allergic disease in twins, J Allergy Clin Immunol, 73, 265, 10.1016/S0091-6749(84)80018-4
Palmer, 2000, Familial aggregation and heritability of asthma-associated quantitative traits in a population-based sample of nuclear families, Eur J Hum Genet, 8, 853, 10.1038/sj.ejhg.5200551
Gerrard, 1976, The familial incidence of allergic disease, Ann Allergy, 36, 10
von Mutius, 1996, Familial aggregation of asthma in a South Bavarian population, Am J Respir Crit Care Med, 153, 1266, 10.1164/ajrccm.153.4.8616552
Sarafino, 1995, Genetic factors in the presence, severity, and triggers of asthma, Arch Dis Child, 73, 112, 10.1136/adc.73.2.112
Pin, 2002, Familial resemblance of asthma severity in the EGEA∗ study, Am J Respir Crit Care Med, 165, 185, 10.1164/ajrccm.165.2.2012019
Teerlink, 2007, A genealogical assessment of heritable predisposition to asthma mortality, Am J Respir Crit Care Med, 176, 865, 10.1164/rccm.200703-448OC
Weidinger, 2008, Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus, PLoS Genet, 4, e1000166, 10.1371/journal.pgen.1000166
Gudbjartsson, 2009, Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction, Nat Genet, 41, 342, 10.1038/ng.323
Graves, 2000, A cluster of seven tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of white children, J Allergy Clin Immunol, 105, 506, 10.1067/mai.2000.104940
Heinzmann, 2000, Genetic variants of IL-13 signalling and human asthma and atopy, Hum Mol Genet, 9, 549, 10.1093/hmg/9.4.549
Howard, 2001, Identification and association of polymorphisms in the interleukin-13 gene with asthma and atopy in a Dutch population, Am J Respir Cell Mol Biol, 25, 377, 10.1165/ajrcmb.25.3.4483
Liu, 2000, An IL13 coding region variant is associated with a high total serum IgE level and atopic dermatitis in the German multicenter atopy study (MAS-90), J Allergy Clin Immunol, 106, 167, 10.1067/mai.2000.107935
Vladich, 2005, IL-13 R130Q, a common variant associated with allergy and asthma, enhances effector mechanisms essential for human allergic inflammation, J Clin Invest, 115, 747, 10.1172/JCI200522818
Wang, 2003, A common IL-13 Arg130Gln single nucleotide polymorphism among Chinese atopy patients with allergic rhinitis, Hum Genet, 113, 387, 10.1007/s00439-003-1001-x
Andrews, 2006, IL-13 receptor alpha 2: a regulator of IL-13 and IL-4 signal transduction in primary human fibroblasts, J Allergy Clin Immunol, 118, 858, 10.1016/j.jaci.2006.06.041
Li, 2010, Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions, J Allergy Clin Immunol, 125, 328, 10.1016/j.jaci.2009.11.018
Willemsen, 2008, Heritability of self-reported asthma and allergy: a study in adult Dutch twins, siblings and parents, Twin Res Hum Genet, 11, 132, 10.1375/twin.11.2.132
Palmer, 2006, Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis, Nat Genet, 38, 441, 10.1038/ng1767
Baurecht, 2007, Toward a major risk factor for atopic eczema: meta-analysis of filaggrin polymorphism data, J Allergy Clin Immunol, 120, 1406, 10.1016/j.jaci.2007.08.067
Palmer, 2007, Filaggrin null mutations are associated with increased asthma severity in children and young adults, J Allergy Clin Immunol, 120, 64, 10.1016/j.jaci.2007.04.001
Marenholz, 2006, Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march, J Allergy Clin Immunol, 118, 866, 10.1016/j.jaci.2006.07.026
Soderhall, 2007, Variants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis, PLoS Biol, 5, e242, 10.1371/journal.pbio.0050242
Lucas, 2004, Small size at birth and greater postnatal weight gain: relationships to diminished infant lung function, Am J Respir Crit Care Med, 170, 534, 10.1164/rccm.200311-1583OC
Van Eerdewegh, 2002, Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness, Nature, 418, 426, 10.1038/nature00878
Haitchi, 2005, ADAM33 expression in asthmatic airways and human embryonic lungs, Am J Respir Crit Care Med, 171, 958, 10.1164/rccm.200409-1251OC
Simpson, 2005, Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33) predict impaired early-life lung function, Am J Respir Crit Care Med, 172, 55, 10.1164/rccm.200412-1708OC
Sadeghnejad, 2009, Adam33 polymorphisms are associated with COPD and lung function in long-term tobacco smokers, Respir Res, 10, 21, 10.1186/1465-9921-10-21
van Diemen, 2005, A disintegrin and metalloprotease 33 polymorphisms and lung function decline in the general population, Am J Respir Crit Care Med, 172, 329, 10.1164/rccm.200411-1486OC
Hancock, 2010, Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function, Nat Genet, 42, 45, 10.1038/ng.500
Repapi, 2010, Genome-wide association study identifies five loci associated with lung function, Nat Genet, 42, 36, 10.1038/ng.501
Hunninghake, 2009, MMP12, lung function, and COPD in high-risk populations, N Engl J Med, 361, 2599, 10.1056/NEJMoa0904006
Allen, 2003, Positional cloning of a novel gene influencing asthma from Chromosome 2q14, Nat Genet, 35, 258, 10.1038/ng1256
Balaci, 2007, IRAK-M is involved in the pathogenesis of early-onset persistent asthma, Am J Hum Genet, 80, 1103, 10.1086/518259
Nicolae, 2005, Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21, Am J Hum Genet, 76, 349, 10.1086/427763
Zhang, 2003, Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma, Nat Genet, 34, 181, 10.1038/ng1166
Laitinen, 2004, Characterization of a common susceptibility locus for asthma-related traits, Science, 304, 300, 10.1126/science.1090010
Barton, 2009, PLAUR polymorphisms are associated with asthma, PLAUR levels, and lung function decline, J Allergy Clin Immunol, 123, 1391, 10.1016/j.jaci.2009.03.014
Koppelman, 2009, Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness, Am J Respir Crit Care Med, 180, 929, 10.1164/rccm.200810-1621OC
Moffatt, 2007, Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma, Nature, 448, 470, 10.1038/nature06014
Sleiman, 2010, Variants of DENND1B associated with asthma in children, N Engl J Med, 362, 36, 10.1056/NEJMoa0901867
Himes, 2009, Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene, Am J Hum Genet, 84, 581, 10.1016/j.ajhg.2009.04.006
Holgate, 2007, Local genetic and environmental factors in asthma disease pathogenesis: chronicity and persistence mechanisms, Eur Respir J, 29, 793, 10.1183/09031936.00087506
Barnes, 2010, An update on the genetics of atopic dermatitis: scratching the surface in 2009, J Allergy Clin Immunol, 125, 16, 10.1016/j.jaci.2009.11.008
Martinez, 2007, Genes, environments, development and asthma: a reappraisal, Eur Respir J, 29, 179, 10.1183/09031936.00087906
Schaub, 2006, The many faces of the hygiene hypothesis, J Allergy Clin Immunol, 117, 969, 10.1016/j.jaci.2006.03.003
Henderson, 2008, Household chemicals, persistent wheezing and lung function: effect modification by atopy?, Eur Respir J, 31, 547, 10.1183/09031936.00086807
Shaheen, 2002, Paracetamol use in pregnancy and wheezing in early childhood, Thorax, 57, 958, 10.1136/thorax.57.11.958
Davey Smith, 2005, What can Mendelian randomisation tell us about modifiable behavioural and environmental exposures?, BMJ, 330, 1076, 10.1136/bmj.330.7499.1076
Sheehan, 2008, Mendelian randomisation and causal inference in observational epidemiology, PLoS Med, 5, e177, 10.1371/journal.pmed.0050177
Shaheen, 2007, Maternal and child glutathione-S-transferase M1 polymorphism modifies risk of childhood asthma associated with prenatal paracetamol exposure, Early Hum Dev, 83, S59, 10.1016/S0378-3782(07)70096-8
Cullen, 2008, The application of genetic information for regulatory standard setting under the Clean Air Act: a decision-analytic approach, Risk Anal, 28, 877, 10.1111/j.1539-6924.2008.01084.x
Houlston, 1998, Modifier genes in humans: strategies for identification, Eur J Hum Genet, 6, 80, 10.1038/sj.ejhg.5200156
Contopoulos-Ioannidis, 2005, Meta-analysis of the association of beta2-adrenergic receptor polymorphisms with asthma phenotypes, J Allergy Clin Immunol, 115, 963, 10.1016/j.jaci.2004.12.1119
Holloway, 2000, Association of beta2-adrenergic receptor polymorphisms with severe asthma, Clin Exp Allergy, 30, 1097, 10.1046/j.1365-2222.2000.00929.x
Chagani, 1999, Prevalence of tumor necrosis factor-alpha and angiotensin converting enzyme polymorphisms in mild/moderate and fatal/near-fatal asthma, Am J Respir Crit Care Med, 160, 278, 10.1164/ajrccm.160.1.9808032
Yao, 2003, The RANTES promoter polymorphism: a genetic risk factor for near-fatal asthma in Chinese children, J Allergy Clin Immunol, 111, 1285, 10.1067/mai.2003.1506
Moore, 2010, Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program, Am J Respir Crit Care Med, 181, 315, 10.1164/rccm.200906-0896OC
Orie, 1961, The host factor in bronchitis, 43
Kraft, 2006, Asthma and chronic obstructive pulmonary disease exhibit common origins in any country!, Am J Respir Crit Care Med, 174, 238, 10.1164/rccm.2604007
Barnes, 2006, Against the Dutch hypothesis: asthma and chronic obstructive pulmonary disease are distinct diseases, Am J Respir Crit Care Med, 174, 240, 10.1164/rccm.2604008
Gao, 2006, Association between polymorphism of tumour necrosis factor alpha-308 gene promoter and asthma: a meta-analysis, Thorax, 61, 466, 10.1136/thx.2005.051284
Ruse, 2007, Tumour necrosis factor gene complex polymorphisms in chronic obstructive pulmonary disease, Respir Med, 101, 340, 10.1016/j.rmed.2006.05.017
Postma, 2004, Rationale for the Dutch hypothesis. Allergy and airway hyperresponsiveness as genetic factors and their interaction with environment in the development of asthma and COPD, Chest, 126, 96S, 10.1378/chest.126.2_suppl_1.96S
Marx-Stolting, 2007, Pharmacogenetics and ethical considerations: why care?, Pharmacogenomics J, 7, 293, 10.1038/sj.tpj.6500425
Calsbeek, 2007, Knowledge and attitudes towards genetic testing: a two year follow-up study in patients with asthma, diabetes mellitus and cardiovascular disease, J Genet Couns, 16, 493, 10.1007/s10897-006-9085-9
Fenwick, 2010, Are guidelines for genetic testing of children necessary?, Fam Cancer, 9, 23, 10.1007/s10689-009-9278-0
Wu, 2010, Development of a Pharmacogenetic Predictive Test in asthma: proof of concept, Pharmacogenet Genomics, 20, 86, 10.1097/FPC.0b013e32833428d0