Anti-inflammatory drug approach: Synthesis and biological evaluation of novel pyrazolo[3,4-d]pyrimidine compounds

Bakavoli, 2010, Eur. J. Med. Chem., 45, 647, 10.1016/j.ejmech.2009.10.051 Curran, 2010, Bioorg. Med. Chem. Lett., 20, 1440, 10.1016/j.bmcl.2009.12.086 Kim, 2010, Bioorg. Med. Chem. Lett., 20, 922, 10.1016/j.bmcl.2009.12.070 Yuan, 2013, Eur. J. Med. Chem., 67, 152, 10.1016/j.ejmech.2013.05.019 Schenone, 2008, Eur. J. Med. Chem., 43, 2665, 10.1016/j.ejmech.2008.01.034 Wang, 2008, J. Med. Chem., 51, 4672, 10.1021/jm800343j Mukaiyama, 2008, Bioorg. Med. Chem., 16, 909, 10.1016/j.bmc.2007.10.068 P. Zang, M. Pennel, J. Wright, W. Chen, M. Leleti, Y. Li, L. Li, Y. Xu, PCT. Int. Appl. WO 2007002293, Chemocentryx, USA. S. Saggar, T. Tucker, R. Tynebor, D. Su, N. Anthony, US. Patent. Appl. US 20070214422007. Anderson, 1990, J. Heterocycl. Chem., 27, 439, 10.1002/jhet.5570270262 Avila, 1986, Comp. Biochem. Physiol. C: Pharmacol. Toxicol. Endrocrinol., 83, 291, 10.1016/0742-8413(86)90125-8 Li, 2006, Arch. Pharm. Chem. Life Sci., 339, 593, 10.1002/ardp.200600098 Manetti, 2007, J. Med. Chem., 50, 5579, 10.1021/jm061449r A. Feurer, J. Luithle, S. Wirtz, G. Koenig, J. Stasch, E. Stahl, R. Schreiber, F. Wunder, D. Lang, PCT. Int. Appl. WO 2004009589, Bayer Healthcare AG, Germany. Chen, 2017, Med. Chem. Comm., 8, 1706, 10.1039/C7MD00209B Karthik, 2018, Med. Chem. Comm., 9, 713, 10.1039/C7MD00628D Li, 2018, Bioorg. Chem., 81, 389, 10.1016/j.bioorg.2018.08.024 Revankar, 2017, Bioorg. Chem., 71, 146, 10.1016/j.bioorg.2017.02.001 Wang, 2017, Med. Chem. Comm., 8, 1173, 10.1039/C7MD00111H Zhao, 2019, Eur. J. Med. Chem., 162, 679, 10.1016/j.ejmech.2018.11.017 Revesz, 2006, Bioorg. Med. Chem. Lett., 16, 262, 10.1016/j.bmcl.2005.10.015 Das, 2008, Bioorg. Med. Chem. Lett., 18, 2652, 10.1016/j.bmcl.2008.03.019 Liu, 2008, Bioorg. Med. Chem. Lett., 18, 1874, 10.1016/j.bmcl.2008.02.011 Rostom, 2009, Bioorg. Med. Chem., 17, 882, 10.1016/j.bmc.2008.11.035 Dannhardt, 2001, Eur. J. Med. Chem., 36, 109, 10.1016/S0223-5234(01)01197-7 Yoshimura, 2011, Protein Expr. Purif., 80, 41, 10.1016/j.pep.2011.05.009 Peri, 1995, J. Biol. Chem., 270, 24615, 10.1074/jbc.270.41.24615 Menozzi, 2003, Farmaco, 58, 795, 10.1016/S0014-827X(03)00136-8 Palomer, 2002, J. Med. Chem., 45, 1402, 10.1021/jm010458r Tewari, 2010, Chem. Pharm. Bull (Tokyo), 58, 634, 10.1248/cpb.58.634 Youssef, 2010, Bioorg. Med. Chem., 18, 5685, 10.1016/j.bmc.2010.06.018 Cheng, 1956, J. Org. Chem., 21, 1240, 10.1021/jo01117a010 Duggan, 2010, J. Biol. Chem., 285, 34950, 10.1074/jbc.M110.162982 Winter, 1962, Proc. Soc. Exp. Biol. Med., 111, 544, 10.3181/00379727-111-27849 Adeyemi, 2002, Fitoterapia, 73, 375, 10.1016/S0367-326X(02)00118-1 Robert, 1957, Acta Endocrinol., 25, 105, 10.1530/acta.0.0250105 Shastry, 2011, Int. J. Pharm. Pharm. Sci., 3, 241 Sidhu, 2010, Biochemistry, 49, 7069, 10.1021/bi1003298 Wang, 2010, Bioorg. Med. Chem. Lett., 20, 7159, 10.1016/j.bmcl.2010.07.054 C.C. Group, Molecular Operating Environment. Brisson, 2004, Mol. Pharmacol., 66, 824, 10.1124/mol.104.001784 L. Schrödinger, Small-Molecule Drug Discovery Suite, in: Glide version 6.7, 2015. Jorgensen, 1988, J. Am. Chem. Soc., 110, 1657, 10.1021/ja00214a001 Friesner, 2006, J. Med. Chem., 49, 6177, 10.1021/jm051256o