Effects of berberine and metformin on intestinal inflammation and gut microbiome composition in db/db mice

Biomedicine & Pharmacotherapy - Tập 118 - Trang 109131 - 2019
Wang Zhang1,2, Ji-Hao Xu1, Tao Yu1, Qi-Kui Chen1
1Department of Gastroenterology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107 Yan Jiang Xi Road, Guangzhou, Guangdong, 510120, PR China
2Department of Gastroenterology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, 111 Da De Road, Guangzhou, Guangdong, 510120, PR China

Tài liệu tham khảo

Tang, 2009, Berberine and Coptidis rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations, J. Ethnopharmacol., 126, 5, 10.1016/j.jep.2009.08.009 Kong, 2004, Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins, Nat. Med., 10, 1344, 10.1038/nm1135 Zhang, 2008, Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine, J. Clin. Endocrinol. Metab., 93, 2559, 10.1210/jc.2007-2404 Vuddanda, 2010, Berberine: a potential phytochemical with multispectrum therapeutic activities, Expert Opin. Investig. Drugs, 19, 1297, 10.1517/13543784.2010.517745 Zhang, 2015, Effect of berberine in treating type 2 diabetes mellitus and complications and its relevant mechanisms, China J. Chin. Mater. Med. Zhongguo Zhong Yao Za Zhi, 40, 1660 Hua, 2007, Determination of berberine in human plasma by liquid chromatography-electrospray ionization-mass spectrometry, J. Pharm. Biomed. Anal., 44, 931, 10.1016/j.jpba.2007.03.022 Zhang, 2012, Structural changes of gut microbiome during berberine-mediated prevention of obesity and insulin resistance in high-fat diet-fed rats, PLoS One, 7 Cabreiro, 2013, Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism, Cell, 153, 228, 10.1016/j.cell.2013.02.035 Shin, 2014, An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice, Gut, 63, 727, 10.1136/gutjnl-2012-303839 Xie, 2011, Effects and action mechanisms of berberine and Rhizoma coptidis on gut microbes and obesity in high-fat diet-fed C57BL/6J mice, PLoS One, 6, 10.1371/journal.pone.0024520 Bailey, 2017, Metformin: historical overview, Diabetologia, 60, 1566, 10.1007/s00125-017-4318-z He, 2009, Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein, Cell, 137, 635, 10.1016/j.cell.2009.03.016 Zhou, 2001, Role of AMP-activated protein kinase in mechanism of metformin action, J. Clin. Invest., 108, 1167, 10.1172/JCI13505 Mahmood, 2013, Metformin: the hidden chronicles of a magic drug, Eur. J. Intern. Med., 24, 20, 10.1016/j.ejim.2012.10.011 Pollak, 2017, The effects of metformin on gut microbiota and the immune system as research frontiers, Diabetologia, 60, 1662, 10.1007/s00125-017-4352-x Hao, 2017, Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug, Nat. Med., 23, 850 Byndloss, 2018, Healthy hosts rule within: ecological forces shaping the gut microbiota, Mucosal Immunol., 11, 1299, 10.1038/s41385-018-0010-y Sano, 2009, Prevention of proliferative changes of forestomach mucosa by blood glucose control with insulin in alloxan-induced diabetic rats, Cancer Sci., 100, 595, 10.1111/j.1349-7006.2008.01081.x Min, 2014, Abnormal differentiation of intestinal epithelium and intestinal barrier dysfunction in diabetic mice associated with depressed Notch/NICD transduction in Notch/Hes1 signal pathway, Cell Biol. Int., 38, 1194, 10.1002/cbin.10323 Martínez, 2013, Diarrhoea-predominant irritable bowel syndrome: an organic disorder with structural abnormalities in the jejunal epithelial barrier, Gut, 62, 1160, 10.1136/gutjnl-2012-302093 DeSantis, 2006, NAST: a multiple sequence alignment server for comparative analysis of 16S rRNA genes, Nucleic Acids Res., 34, W394, 10.1093/nar/gkl244 Caporaso, 2010, QIIME allows analysis of high-throughput community sequencing data, Nat. Methods, 7, 335, 10.1038/nmeth.f.303 Lozupone, 2005, UniFrac: a new phylogenetic method for comparing microbial communities, Appl. Environ. Microbiol., 71, 8228, 10.1128/AEM.71.12.8228-8235.2005 Tibshirani, 2002, Diagnosis of multiple cancer types by shrunken centroids of gene expression, Proc. Natl. Acad. Sci. U. S. A., 99, 6567, 10.1073/pnas.082099299 Bharti, 2002, Nuclear factor-kappa B and cancer: its role in prevention and therapy, Biochem. Pharmacol., 64, 883, 10.1016/S0006-2952(02)01154-1 Takeda, 2003, Toll-like receptors, Annu. Rev. Immunol., 21, 335, 10.1146/annurev.immunol.21.120601.141126 Murugesan, 2018, Gut microbiome production of short-chain fatty acids and obesity in children, Eur. J. Clin. Microbiol. Infect. Dis., 37, 621, 10.1007/s10096-017-3143-0 Sonnenburg, 2010, Specificity of polysaccharide use in intestinal bacteroides species determines diet-induced microbiota alterations, Cell, 141, 1241, 10.1016/j.cell.2010.05.005 Smith, 2013, The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis, Science, 341, 569, 10.1126/science.1241165 Neyrinck, 2011, Prebiotic effects of wheat arabinoxylan related to the increase in bifidobacteria, Roseburia and Bacteroides/Prevotella in diet-induced obese mice, PLoS One, 6, 10.1371/journal.pone.0020944 Maslowski, 2009, Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43, Nature, 461, 1282, 10.1038/nature08530 De Filippo, 2010, Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa, Proc. Natl. Acad. Sci. U. S. A., 107, 14691, 10.1073/pnas.1005963107 Qin, 2012, A metagenome-wide association study of gut microbiome in type 2 diabetes, Nature, 490, 55, 10.1038/nature11450 Biagi, 2010, Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians, PLoS One, 5 Ryan, 2014, FXR is a molecular target for the effects of vertical sleeve gastrectomy, Nature, 509, 183, 10.1038/nature13135 Peng, 2015, Antibacterial activity and mechanism of berberine against Streptococcus agalactiae, Int. J. Clin. Exp. Pathol., 8, 5217 Zh, 2015, Modulation of gut microbiota by berberine and metformin during the treatment of high-fat diet-induced obesity in rats, Scientific Reports, 5, 14405, 10.1038/srep14405 Cani, 2008, Changes in gut microbiome control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice, Diabetes, 57, 1470, 10.2337/db07-1403 Dao, 2016, Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology, Gut, 65, 426, 10.1136/gutjnl-2014-308778