Transient and permanent neonatal diabetes
Tóm tắt
Neonatal diabetes, which may be transient or permanent, is rare. Most patients are full-term but small- for-date infants. Typical symptoms of diabetes mellitus occur within the first 4 weeks of life, requiring insulin therapy and very strict blood glucose monitoring. Subsequent growth and psychomotor development are usually normal. In about 33% of these patients the diabetes remains permanent; the transient cases, however, often develop permanent diabetes mellitus later in life. Exocrine pancreatic insufficiency is present in some patients. Neonatal diabetes differs from type-I diabetes in many aspects and seems to form a distinct entity of inborn pancreatic malfunction.
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Abend M, Hochberg Z, Borochowitz Z, Berger A (1982) Low dose iv infusion of insulin on the first day of life in a diabetic ketoacidotic newborn. Eur J Pediatr 138:345
Arey SL (1953) Transient diabetes in infancy. Pediatrics 11:140–143
Assevero VL, Moss JM (1958) Diabetes mellitus in infancy. J Pediatr 53: 227–230
Aziz EM, Lipsitz PJ (1973) A case of transient hypoglycemia and hyperglycemia in a full term neonate. Clinical pediatrics 12:363–366
Barbotte E, Simonin G, Unan D, Coignet J (1986) Le diabete neonatal, a propos de deux observations. Pediatrie 41:553–557
Blethen SA, White NH, Santiago JV, Daughaday WH (1981) Plasma somatomedins, endogenous insulin secretion and growth in transient neonatal diabetes mellitus. J Clin Endocrinol Metab 52:144–147
Briggs JR (1986) Permanent noninsulin dependent diabetes mellitus after transient neonatal diabetes. Scot Med J 31:41–42
Burland WL (1964) Diabetes mellitus syndrome in the newborn infant. J Pediatr 65:122–123
Cahill GF, McDevitts HO (1981) Insulin-dependent diabetes mellitus: the initial lesion. N Engl J Med 304: 1454–1465
Campbell IW, Fraser DM, Duncan LJP, Keay AJ (1978) Permanent insulin dependent diabetes mellitus after congenital temporary diabetes mellitus. BMJ 2:174
Campbell PH, Vay LW, Go MD, et al (1980) Long term survival in a case of functional pancreatic agenesis. J Pediatr 97:786–789
Cavallo L, Mautone A, Laforgia N, et al (1987) Neonatal diabetes mellitus: evaluation of pancreatic β-cell function in two cases. Helv Pediatr Acta 42:437–443
Chance GW, Bower BD (1966) Hypoglycemia and temporary hyperglycemia in infants of low birth weight for maturity. Arch Dis Child 41:279–285
Coffey JD, Killelea DE (1982) Transient neonatal diabetes in half sisters. Am J Dis Child 136:626–627
Coffey JD, Womack NC (1967) Transient neonatal diabetes in half sisters. Am J Dis child 113:480
Cornblath M, Wybreght SH, Baens GS (1963) Tests of carbohydrate tolerance in premature infants. Pediatrics 32:1007–1024
Croxson SC (1988) Insulin dependent diabetes following neonatal diabetes. Austr Pediatr J 24:157
Cuno F (1910) Jb Kinderheilkd 71:623 (quoted from 98)
Dacou-Voutetakis C, Anagnostakis D, Xanthou M (1975) Macroglossia, transient diabetes mellitus and intrauterine growth failure: a new distinct entity? Pediatrics 55:127–131
Devine J (1938) A case of diabetes mellitus in a young infant. Arch Dis Child 13:189–192
Dodge JA, Laurence KM (1977) Congenital absence of islets of Langerhans. Arch Dis Child 52:411–419
Dorchy H, et al (1975) Permanent neonatal diabetes mellitus. Z Kinderheilkd 118:271–281
Dorchy H (1992) Permanent neonatal diabetes: lack of diabetic complications after 20 years follow up (letter). Eur J Pediatr 151(2):151
Dweck HS, Cassady G (1974) Incidence of hyperglycemia in infants of birth weight 1100 g or less. Pediatrics 53:189–195
Edidin DV (1993) Permanent diabetes after transient neonatal diabetes. Lancet 341:1095
Engleson G, Zetterquist P (1957) Congenital diabetes mellitus and neonatal pseudodiabetes mellitus. Arch Dis Child 32:193–196
Ferguson AW, Milner RDG (1970) Transient neonatal diabetes in sibs. Arch Dis Child 45:80–83
Ferguson IC (1967) Neonatal hyperglycemia: case report with plasma insulin studies. Arch Dis Child 42: 509–513
Gans B (1953) Diabetes mellitus in an infant aged 39 days. Proc Roy Soc Med 132:47
Geefhuysen J (1966) Temporary idiopathic neonatal hyperglycemia. Pediatrics 38:1009–1012
Gentz JCH, Cornblath M (1969) Transient diabetes of the newborn. Adv Pediatr 16:345–363
Gerrard JW, Chin W (1962) The syndrome of transient diabetes. J Pediatr 61:89–93
Gottschalk ME, Schatz DA, Claire-Salzer M, et al (1992) Permanent diabetes without serologic evidence of autoimmunity after transient neonatal diabetes. Diabetes Care 15:1273–1276
Grasso S, Messina A, Saporito N, et al (1970) Effect of theophyllin, glucagon and theophyllin plus glucagon on insulin secretion in the premature infant. Diabetes 19:837–841
Green A, Gale EAM, Patterson CC for the Eurodiab Study Group (1992) Incidence of childhod-onset insulin-dependent diabetes mellitus: the EURODIAB ACE study. Lancet 339: 905–909
Greenwood RD, Traisman HS (1971) Permanent diabetes in a neonate. J Pediatr 79:296–298
Guest GM (1948) Infantile diabetes mellitus. Am J Dis Child 75:461–464
Hager H, Herbst R (1966) Das transitorische Diabetes mellitus Syndrom des Neugeborenen, ein Krankheitsbild sui generis. Z Kinderheilkd 95:324–347
Halliday HL, McReid M, Hadden DR (1986) C-Peptide levels in transient neonatal diabetes. Diabetic Med 3: 80–81
Hanßler H, Bartmann P (1984) Permanenter Diabetes des Neugeborenen. Therapiewoche 34:1487–1490
Haschke F, Hohenauer L (1978) Transitorischer Diabetes mellitus bei einem dystrophen Neugeborenen. Helv Pediatr Acta 33:385–392
Hattevig G, Kjellman B, Fällström SP (1982) Congenital permanent diabetes and celiac disease. J Pediatr 101: 955–957
Hesse H (1963) Angeborener Diabetes bei zwei Vettern Kinderärztl. Praxis 31:333–340
Hickish G (1956) Neonatal diabetes. BMJ I:95–96
Hoffmann WH, Khoury C, Byrd HA (1980) Prevalence of permanent congenital diabetes mellitus. Diabetologia 19:487–488
Hofmann-Bang G (1954) Diabetic coma in a three week old infant. Acta Pediatr 43:393
Holland CL, Holland EA (1936) Diabetes mellitus in infancy. W virg Med J 32:407 (quoted from 35)
Hutchison JH, Keay AJ, Kerr MM (1962) Congenital temporary diabetes mellitus. BMJ II:436–440
Ivarsson SA, Marner B, Lermark A, Nilsson KO (1988) Nonislet pancreatic autoantibodies in sibship with permanent insulin dependent diabetes mellitus. Diabetes 37:347–350
Jeune M, Riedweg M (1960) Syndrome diabetique transitoire chez le nouveau-ne. Pediatrie 15:63–66
Jonas MM, Bell MD, Eidson MS, et al (1991) Congenital diabetes mellitus and fatal secretory diarrhea in two infants. J Pediatr Gastroenterol Nutr 13: 415–425
Kasi AM (1964) Neonatal diabetes mellitus. BMJ I:1137
Keidan SE (1955) Transient diabetes in infancy. Arch Dis Child 30:291–296
Kitselle JF (1852) Jb Kinderheilkd 18:313 (quoted from 98)
Kloss JL (1967) Transient diabetes in the newborn. Clin Pediatr 6:303–304
Knip M, Koivisto M, Käär ML, et al (1983) Pancreatic islet cell function and metabolic control in an infant with permanent neonatal diabetes. Acta Paediatr Scand 72:303–307
Kohlhoff R (1988) Congenital type I diabetes. Zentralbl Gynäkol 110: 383–387
Kouvallainen KJ, Väänänen J, Hickkala H (1961) Neonatal pseudodiabetes mellitus. Ann Pediatr Fenn 7: 242–250 (quoted from 37)
Kuna P, Addy DP (1979) Transient neonatal diabetes mellitus. Am J Dis Child 133:65–66
Lawrence RD, McCance RA (1931) Gangrene in an infant, associated with temporary diabetes. Arch Dis Child 6:343–345
LeDune MA (1971) Insulin studies in temporary neonatal hyperglycemia. Arch Dis Child 46:392–394
Lemons JA, Ridenour R, Orsini EN (1979) Congenital absence of the pancreas and intrauterine growth retardation. Pediatrics 64:255–257
Lewis E, Eisenberg H (1935) Diabetes mellitus neonatorum. Am J Dis Child 49:408–411
Lewis SR, Mortimer PE (1964) Idiopathic neonatal hyperglycemia. Arch Dis Child 39:618–624
Lilien LD, Rosenfield RL, Baccaro MM, Pildes RS (1979) Hyperglycemia in stressed small premature neonates. J Pediatr 94:454–459
Limper MA, Millner AJ (1935) Diabetes mellitus with extensive gangrene in early infancy. Am J Dis Child 50:1216–1220
Mathews PM, Hamdan JA (1988) Transient diabetes mellitus in neonatal methylmaluric aciduria. J Inherited Metab Dis 11(2):218–219
Mathew PM, Hann RW, Hamdan JA (1988) Neonatal diabetes in first cousins. Clin Pediatr 27:247–251
McGill JJ, Roberton DM (1986) A new type of transient diabetes mellitus of infancy? Arch Dis Child 61: 334–336
Michaelis D, Jutzi E, Vogt L (1993) Epidemiology of insulin-treated diabetes mellitus in the East-German population. Diabetes Metabol 19: 110–115
Milner RDG, Ferguson AW, Naidu SH (1971) Aetiology of transient neonatal diabetes. Arch Dis Child 46: 724–726
Nawrocka-Kanska B (1952) Diabetes syndrome in intracranial hemorrhage in newborns. Pediatria Polska 27: 1067 (quoted from 28)
Nielsen F (1989) Transitional neonatal diabetes mellitus in a pair of twins. Acta Paediatr Scand 78:469–472
Osborne GR (1965) Congenital diabetes. Arch Dis Child 40:332
Pagliara AS, Karl IE, Kipnis DB (1973) Transient neonatal diabetes: delayed maturation of pancreatic beta cells. J Pediatr 82:97–101
Pildes RS (1986) Neonatal hyperglycemia. J Pediatr 109:905–907
Ramsey WR (1926) Glycosuria of newborn treated with insulin. Tr Am Pediatr Soc 38:100 (quoted from 2)
Reus S, Egidi R, Otten A, Aulepp U (1992) Neonataler Diabetes and Mikrocephalie. Monatsschr Kinderheilkd 140:803–807
Rosskamp R, Zighahn W, Burmeister W (1985) Thiaminabhangige Anämie und Thrombopenie, insulinpflichtiger Diabetes and sensoneuronale Schwerhörigkeit. Klin Pädiatrie 197:315–317
Salero M, Gasparini N, et al (1994) Two interesting cases of transient neonatal diabetes. J Pediatr Endocrinol 7:47–52
Samuelsson G, Ludvigsson J (1988) Transient and permanent neonatal diabetes mellitus in Sweden. Diabetes in the young. Bull ISGD 18:110–111
Scheffner D (1961) Zentraler geburtstraumatischer transitorischer Diabetes. Ann Pediatrie 199:243
Schiff D, Colle E, Stern L (1972) Metabolic and growth patterns in transient neonatal diabetes. N Engl J Med 287:119–122
Shield JPH, Maum JD (1993) Is transient neonatal diabetes a risk factor for diabetes in later life? Lancet 341: 693
Shrinivasan G, Jain R, Pildes RS, et al (1986) Glucose homeostasis during anesthesia and surgery in infants. J Pediatr Surg 21:718–721
Sodoyez-Goffaux F, Sodoyez JC (1977) Transient diabetes melitus in a neonate. J Pediatr 91:395–399
Steigenberger H (1986) Transitorischer Diabetes mellitus des Neugeborenen. Monatsschr Kinderheilkd 134:207–208
Stimmler L, Jensen N, Toseland P (1970) Alaninuria, associated with dwarfism, enamel hypoplasia microcephaly and diabetes mellitus in two sisters. Arch Dis child 45:682–685
Strandquist B (1932) Infantile glucosuria simulating diabetes. Acta Paediatr 13:421–428
Struwe FE (1968) Zur Manifestation des Diabetes mellitus im Kindesalter. Monatsschr Kinderheilkd 108:487–490
Sweetnam WP, Sykes CGW (1962) Congenital diabetes mellitus. BMJ II: 671–672
Taylor SI, Leventhal S (1983) Defect in cooperativity in insulin receptors from a patient with congenital form of extreme insulin resistance. J Clin Invest 71:1676–1685
Ureta A, Jimenez M, Aroyos A, et al (1980) Diabetes transitoria neonatal. Ann Esp Pediatr 13:619–624
Vanelli M, DeFanti A, Cantoni S, Chiari G (1994) Transient neonatal diabetes: a relapse after 10 years of complete remission. Acta Diabetol 31: 116–118
Vries LS de (1980) Het syndroom van voorbijgaande diabetes mellitus bij de pasgeborene. Ned T Geneesk 124: 1920–1922
Weimerskirch D, Klein DJ (1993) Recurrence of IDDM after transient neonatal diabetes. J Pediatr 122:598–600
Widness JA, Cowett RM, Zeller WP, et al (1982) Permanent neonatal diabetes in an infant of an insulin-dependent mother. J Pediatr 100:926–929
Willi H, Müller F (1968) Über den transitorischen Diabetes des Neugeborenen. Helv Pediatr Acta 23:231–241
Winter WE, MacLaren NK, Riley WJ, et al (1986) congenital pancreatic hypoplasia: a syndrome of exocrine and endocrine pancreatic insufficiency. J Pediatr 109:465–468
Wright NM, Metzger DL, Borowitz SM, Clarke WL (✉) Permanent neonatal diabetes mellitus and pancreatic exocrine insulfficiency resulting from congenital pancreatic agenesis. Am J Dis Child 147:607–609
Wong HB (1957) Diabetes in a two month old chinese baby. Arch Dis Child 32:197–198
Wong KC, Tse K, Chan JK (1988) Congenital absence of insulin secreting cells. Histopathology 12:541–545
Wylie MES (1953) A case of congenital diabetes. Arch Dis Child 28:297–299
Zarif M, Pildes R, Vidyasagar D (1976) Insulin and growth hormone responses in neonatal hyperglycemia. Diabetes 25:428–433
Zeller J, Voyer M, Bourgneres PI (1994) Hyperglycemies et diabete neonatal. Arch Pédiatr 1(6) 561–567