A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging

Cell Metabolism - Tập 22 - Trang 895-906 - 2015
Mark A. McCormick1, Joe R. Delaney2,3, Mitsuhiro Tsuchiya1, Scott Tsuchiyama1, Anna Shemorry2, Sylvia Sim2, Annie Chia-Zong Chou2, Umema Ahmed2, Daniel Carr2, Christopher J. Murakami2, Jennifer Schleit2, George L. Sutphin4,3, Brian M. Wasko2, Christopher F. Bennett2,3, Adrienne M. Wang2, Brady Olsen2, Richard P. Beyer5, Theodor K. Bammler5, Donna Prunkard2, Simon C. Johnson2
1Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945, USA
2Department of Pathology, University of Washington, Seattle, WA, 98195, USA
3Molecular and Cellular Biology Program, University of Washington, Seattle, WA 98195 USA
4Department of Pathology, University of Washington, Seattle, WA 98195, USA
5Department of Occupational and Environmental Health Sciences, University of Washington, Seattle, WA 98195, USA

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