Delivery of osteoinductive growth factors from degradable PEG hydrogels influences osteoblast differentiation and mineralization

Bauer, 2000, Bone graft materials—an overview of the basic science, Clin. Orthop., 371, 10, 10.1097/00003086-200002000-00003 Freed, 1999, Frontiers of tissue engineering, Clin. Orthop., 367S, S46, 10.1097/00003086-199910001-00006 Jackson, 1999, Tissue engineering principles in orthopaedic surgery, Clin. Orthop., 367S, S31, 10.1097/00003086-199910001-00005 Burg, 2000, Biomaterial developments for bone tissue engineering, Biomaterials, 21, 2347, 10.1016/S0142-9612(00)00102-2 Anselme, 2000, Osteoblast adhesion on biomaterials, Biomaterials, 21, 667, 10.1016/S0142-9612(99)00242-2 Haynesworth, 1992, Characterization of cells with osteogenic potential from human marrow, Bone, 13, 81, 10.1016/8756-3282(92)90364-3 Majors, 1997, Characterization of human bone marrow stromal cells with respect to osteoblastic differentiation, J. Orthop. Res., 15, 546, 10.1002/jor.1100150410 Urist, 1997, Bone morphogenetic protein: the molecularization of skeletal system development, J. Bone Joint Surg., 12, 343 Centralla, 1994, Transforming growth factor-β gene family members and bone, Endocr. Rev., 15, 27 Yasko, 1992, The healing of segmental defects, induced by recombinant human bone morphogenetic protein (rhBMP-2), J. Bone Joint Surg., 74A, 659, 10.2106/00004623-199274050-00005 Hollinger, 1998, Recombinant human bone morphogenetic protein-2 and collagen for bone regeneration, J. Biomed. Mater. Res., 43, 356, 10.1002/(SICI)1097-4636(199824)43:4<356::AID-JBM3>3.0.CO;2-7 Yamamoto, 1998, Ectopic bone formation induced by biodegradable hydrogels incorporating bone morphogenetic protein, J. Biomatter. Sci. Polym. Ed., 9, 439, 10.1163/156856298X00550 Kirker-Head, 1998, Healing bone using recombinant human bone morphogenetic protein 2 and copolymer, Clin. Orthop., 349, 205, 10.1097/00003086-199804000-00026 Winn, 1999, Tissue-engineered bone biomimetic to regenerate calvarial critical-sized defects in athymic rats, J. Biomed. Mater. Res., 45, 414, 10.1002/(SICI)1097-4636(19990615)45:4<414::AID-JBM17>3.0.CO;2-Z Lucas, 1990, Ectopic induction of cartilage and bone by water-soluble proteins from bovine bone using a polyanhydride delivery vehicle, J. Biomed. Mater. Res., 24, 901, 10.1002/jbm.820240708 Sawhney, 1993, Bioerodible hydrogels based on photopolymerized poly(ethylene glycol)-co-poly(α-hydroxy acid) diacrylate macromers, Macromolecules, 26, 581, 10.1021/ma00056a005 Hill-West, 1994, Prevention of postoperative adhesions in the rat by in situ photopolymerization of bioresorbable hydrogel barriers, Obstet. Gynaecol., 83, 59 West, 1995, Photopolymerized hydrogel materials for drug-delivery applications, React. Polym., 25, 139, 10.1016/0923-1137(94)00096-N Mason, 2001, Predicting controlled-release behavior of degradable PLA-b-PEG-b-PLA hydrogels, Macromolecules, 34, 4630, 10.1021/ma010025y Anseth, 2002, In situ forming degradable networks and their application in tissue engineering and drug delivery, J. Controlled Release, 78, 199, 10.1016/S0168-3659(01)00500-4 Elisseeff, 1999, Transdermal photopolymerization for minimally invasive implantation, Proc. Natl. Acad. Sci. U.S.A., 96, 3104, 10.1073/pnas.96.6.3104 Elisseeff, 1999, Transdermal photopolymerization of poly(ethylene oxide)-based injectable hydrogels for tissue-engineered cartilage, Plast. Reconstr. Surg., 104, 1014, 10.1097/00006534-199909040-00017 S. Bryant, P. Martens, J. Elisseeff, M. Randolph, R. Langer, K.S. Anseth, in: B.T. Stokke, Elgsaeter (Eds.), Chemical and Physical Network Formation and Control of Properties, Wiley Polymer Group Review Series, 1999, pp. 396–403. Bryant, 2000, Cytocompatibility of UV and visible light photoinitiating systems on cultured NIH/3T3 fibroblasts in vitro, J. Biomaterials Sci. Polym. Ed., 11, 439, 10.1163/156856200743805 Ishaug, 1994, Osteoblast function on synthetic biodegradable polymers, J. Biomed. Mater. Res., 28, 1445, 10.1002/jbm.820281210 Roethy, 2001, A growth factor mixture that significantly enhances angiogenesis in vivo, J. Pharmacol. Exp. Ther., 2, 494 Elliott, 2001, Kinetic modeling of the effect of solvent concentration on primary cyclization during polymerization of multifunctional monomers, Chem. Eng. Sci., 56, 3173, 10.1016/S0009-2509(00)00547-9 Quarles, 1992, Distinct proliferative and differentiated stages of murine MC3T3-E1 cells in culture: in vitro model of osteoblast development, J. Bone Miner. Res., 7, 683, 10.1002/jbmr.5650070613 Stein, 1990, Relationship of cell-growth to the regulation of tissue-specific gene-expression during osteoblast differentiation, FASEB J., 4, 3111, 10.1096/fasebj.4.13.2210157