Surface Density-Induced Pleating of a Lipid Monolayer Drives Nascent High-Density Lipoprotein Assembly

Anantharamaiah, 1985, Studies of synthetic peptide analogs of the amphipathic helix. Structure of complexes with dimyristoyl phosphatidylcholine, J. Biol. Chem., 260, 10248, 10.1016/S0021-9258(17)39238-4 Atkinson, 1980, X-ray and neutron scattering studies of plasma lipoproteins, Ann. N. Y. Acad. Sci., 348, 284, 10.1111/j.1749-6632.1980.tb21308.x Baoukina, 2008, The molecular mechanism of lipid monolayer collapse, Proc. Natl. Acad. Sci. USA, 105, 10803, 10.1073/pnas.0711563105 Bashkirov, 2008, GTPase cycle of dynamin is coupled to membrane squeeze and release, leading to spontaneous fission, Cell, 135, 1276, 10.1016/j.cell.2008.11.028 Berendsen, 1984, Molecular dynamics with coupling to an external bath, J. Chem. Phys., 81, 3684, 10.1063/1.448118 Bhat, 2007, Conformational adaptation of apolipoprotein A-I to discretely sized phospholipid complexes, Biochemistry, 46, 7811, 10.1021/bi700384t Bodzioch, 1999, The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease, Nat. Genet., 22, 347, 10.1038/11914 Borhani, 1997, Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation, Proc. Natl. Acad. Sci. USA, 94, 12291, 10.1073/pnas.94.23.12291 Brooks-Wilson, 1999, Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency, Nat. Genet., 22, 336, 10.1038/11905 Catte, 2008, Structure of spheroidal HDL particles revealed by combined atomistic and coarse-grained simulations, Biophys. J., 94, 2306, 10.1529/biophysj.107.115857 Choubey, 2013, Cholesterol translocation in a phospholipid membrane, Biophys. J., 104, 2429, 10.1016/j.bpj.2013.04.036 Datta, 2001, Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptide, J. Lipid Res., 42, 1096, 10.1016/S0022-2275(20)31599-6 Davidson, 2007, The structure of apolipoprotein A-I in high density lipoproteins, J. Biol. Chem., 282, 22249, 10.1074/jbc.R700014200 Duong, 2006, Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I, J. Lipid Res., 47, 832, 10.1194/jlr.M500531-JLR200 Epand, 1989, Properties of lipid complexes with amphipathic helix-forming peptides. Role of distribution of peptide charges, J. Biol. Chem., 264, 4628, 10.1016/S0021-9258(18)83789-9 Forte, 1971, Plasma lipoproteins in familial lecithin: cholesterol acyltransferase deficiency: structure of low and high density lipoproteins as revealed by electron microscopy, J. Clin. Invest., 50, 1141, 10.1172/JCI106586 Francis, 1995, Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier disease, J. Clin. Invest., 96, 78, 10.1172/JCI118082 Gu, 2010, Structures of discoidal high density lipoproteins: a combined computational-experimental approach, J. Biol. Chem., 285, 4652, 10.1074/jbc.M109.069914 Hess, 2008, GROMACS 4: algorithms for highly efficient, load-balanced, and scalable molecular simulation, J. Chem. Theor. Comput., 4, 435, 10.1021/ct700301q Humphrey, 1996, VMD: visual molecular dynamics, J. Mol. Graph., 14, 33, 10.1016/0263-7855(96)00018-5 Jones, 2009, Dynamics of activation of lecithin:cholesterol acyltransferase by apolipoprotein A-I, Biochemistry, 48, 11196, 10.1021/bi901242k Jones, 2010, Assessment of the validity of the double superhelix model for reconstituted high density lipoproteins: a combined computational-experimental approach, J. Biol. Chem., 285, 41161, 10.1074/jbc.M110.187799 Jones, 2011, “Sticky” and “promiscuous”, the yin and yang of apolipoprotein A-I termini in discoidal high-density lipoproteins: a combined computational-experimental approach, Biochemistry, 50, 2249, 10.1021/bi101301g Kane, 2012, Prebeta-1 HDL and coronary heart disease, Curr. Opin. Lipidol., 23, 367, 10.1097/MOL.0b013e328353eef1 Koppaka, 1999, The structure of human lipoprotein A-I. Evidence for the “belt” model, J. Biol. Chem., 274, 14541, 10.1074/jbc.274.21.14541 Kozlovsky, 2002, Stalk model of membrane fusion: solution of energy crisis, Biophys. J., 82, 882, 10.1016/S0006-3495(02)75450-7 Landry, 2006, ATP-binding cassette transporter A1 expression disrupts raft membrane microdomains through its ATPase-related functions, J. Biol. Chem., 281, 36091, 10.1074/jbc.M602247200 Lawn, 1999, The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway, J. Clin. Invest., 104, R25, 10.1172/JCI8119 Li, 2004, Double belt structure of discoidal high density lipoproteins: molecular basis for size heterogeneity, J. Mol. Biol., 343, 1293, 10.1016/j.jmb.2004.09.017 Lin, 2000, Apolipoprotein binding to protruding membrane domains during removal of excess cellular cholesterol, Atherosclerosis, 149, 359, 10.1016/S0021-9150(99)00503-1 Markvoort, 2009, Vesicle deformation by draining: geometrical and topological shape changes, J. Phys. Chem. B, 113, 8731, 10.1021/jp901277h Marrink, 2007, The MARTINI force field: coarse grained model for biomolecular simulations, J. Phys. Chem. B, 111, 7812, 10.1021/jp071097f Martin, 2006, Apolipoprotein A-I assumes a “looped belt” conformation on reconstituted high density lipoprotein, J. Biol. Chem., 281, 20418, 10.1074/jbc.M602077200 Monticelli, 2008, The MARTINI coarse-grained force field: Extension to proteins, J. Chem. Theor. Comput., 4, 819, 10.1021/ct700324x Nagata, 2013, ABCA1 dimer-monomer interconversion during HDL generation revealed by single-molecule imaging, Proc. Natl. Acad. Sci. USA, 110, 5034, 10.1073/pnas.1220703110 Palgunachari, 1996, Only the two end helixes of eight tandem amphipathic helical domains of human apo A-I have significant lipid affinity. Implications for HDL assembly, Arterioscler. Thromb. Vasc. Biol., 16, 328, 10.1161/01.ATV.16.2.328 Quazi, 2013, Differential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutants, J. Biol. Chem., 288, 34414, 10.1074/jbc.M113.508812 Rader, 2012, The not-so-simple HDL story: is it time to revise the HDL cholesterol hypothesis?, Nat. Med., 18, 1344, 10.1038/nm.2937 Rust, 1999, Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1, Nat. Genet., 22, 352, 10.1038/11921 Sampaio, 2011, Membrane lipidome of an epithelial cell line, Proc. Natl. Acad. Sci. USA, 108, 1903, 10.1073/pnas.1019267108 Segrest, 1976, Molecular packing of high density lipoproteins: a postulated functional role, FEBS Lett., 69, 111, 10.1016/0014-5793(76)80665-5 Segrest, 1999, A detailed molecular belt model for apolipoprotein A-I in discoidal high density lipoprotein, J. Biol. Chem., 274, 31755, 10.1074/jbc.274.45.31755 Sloop, 1983, Characterization of dog peripheral lymph lipoproteins: the presence of a disc-shaped “nascent” high density lipoprotein, J. Lipid Res., 24, 1429, 10.1016/S0022-2275(20)37866-4 Tricerri, 2001, Arrangement of apolipoprotein A-I in reconstituted high-density lipoprotein disks: an alternative model based on fluorescence resonance energy transfer experiments, Biochemistry, 40, 5065, 10.1021/bi002815q Vedhachalam, 2007, Mechanism of ATP-binding cassette transporter A1-mediated cellular lipid efflux to apolipoprotein A-I and formation of high density lipoprotein particles, J. Biol. Chem., 282, 25123, 10.1074/jbc.M704590200 Voight, 2012, Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study, Lancet, 380, 572, 10.1016/S0140-6736(12)60312-2 Wilson, 1988, High density lipoprotein cholesterol and mortality. The Framingham Heart Study, Arteriosclerosis, 8, 737, 10.1161/01.ATV.8.6.737 Wlodawer, 1979, High-density lipoprotein recombinants: evidence for a bicycle tire micelle structure obtained by neutron scattering and electron microscopy, FEBS Lett., 104, 231, 10.1016/0014-5793(79)80821-2 Zhang, 2011, The morphology and structure of lipoprotein revealed by optimized negative staining, J. Lipid Res., 52, 175, 10.1194/jlr.D010959