Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes

Cell - Tập 159 - Trang 374-387 - 2014
Jill M. Dowen1, Zi Peng Fan1,2, Denes Hnisz1, Gang Ren3,4, Brian J. Abraham1, Lyndon N. Zhang1,5, Abraham S. Weintraub1,5, Jurian Schuijers1, Tong Ihn Lee1, Keji Zhao3, Richard A. Young1,6
1Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142 USA
2Computational and Systems Biology Program, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
3Systems Biology Center, NHLBI, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
4College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, P.R. China 712100
5Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA
6Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA

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