Endotyping early childhood asthma by quantitative symptom assessment

Journal of Allergy and Clinical Immunology - Tập 127 - Trang 1155-1164.e2 - 2011
Hans Bisgaard1, Christian Bressen Pipper1, Klaus Bønnelykke1
1Copenhagen Prospective Studies on Asthma in Childhood; Health Sciences, University of Copenhagen; and the Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Copenhagen, Denmark

Tài liệu tham khảo

Kocevar, 2004, Variations in pediatric asthma hospitalization rates and costs between and within Nordic countries, Chest, 125, 1680, 10.1378/chest.125.5.1680 Weiss, 2000, Trends in the cost of illness for asthma in the United States, 1985-1994, J Allergy Clin Immunol, 106, 493, 10.1067/mai.2000.109426 Warren, 2006, Asthma as a disease concept, Lancet, 368, 1416, 10.1016/S0140-6736(06)69596-2 Bush, 2009, Practice imperfect—treatment for wheezing in preschoolers, N Engl J Med, 360, 409, 10.1056/NEJMe0808951 Anderson, 2008, Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease, Lancet, 372, 1107, 10.1016/S0140-6736(08)61452-X Wenzel, 2006, Asthma: defining of the persistent adult phenotypes, Lancet, 368, 804, 10.1016/S0140-6736(06)69290-8 Cane, 2000, What do parents of wheezy children understand by “wheeze”?, Arch Dis Child, 82, 327, 10.1136/adc.82.4.327 Cane, 2001, Parents’ interpretations of children’s respiratory symptoms on video, Arch Dis Child, 84, 31, 10.1136/adc.84.1.31 Crane, 2003, Agreement between written and video questions for comparing asthma symptoms in ISAAC, Eur Respir J, 21, 455, 10.1183/09031936.03.00041403 Van Sickle, 2005, Perceptions of asthma among physicians: an exploratory study with the ISAAC video, Eur Respir J, 26, 829, 10.1183/09031936.05.00027205 Michel, 2006, Parental understanding of wheeze and its impact on asthma prevalence estimates, Eur Respir J, 28, 1124, 10.1183/09031936.06.00008406 Mohangoo, 2010, A comparison of parent-reported wheezing or shortness of breath among infants as assessed by questionnaire and physician-interview: the Generation R study, Pediatr Pulmonol, 45, 500 Bisgaard, 2006, Intermittent inhaled corticosteroids in infants with episodic wheezing, N Engl J Med, 354, 1998, 10.1056/NEJMoa054692 Bisgaard, 2007, Childhood asthma after bacterial colonization of the airway in neonates, N Engl J Med, 357, 1487, 10.1056/NEJMoa052632 Martinez, 1995, Asthma and wheezing in the first six years of life. The Group Health Medical Associates, N Engl J Med, 332, 133, 10.1056/NEJM199501193320301 Henderson, 2008, Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood, Thorax, 63, 974, 10.1136/thx.2007.093187 Moffatt, 2007, Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma, Nature, 448, 470, 10.1038/nature06014 Bisgaard, 2004, The Copenhagen Prospective Study on Asthma in Childhood (COPSAC): design, rationale, and baseline data from a longitudinal birth cohort study, Ann Allergy Asthma Immunol, 93, 381, 10.1016/S1081-1206(10)61398-1 Bisgaard, 2010, Association of bacteria and viruses with wheezy episodes in young children: prospective birth cohort study, BMJ, 341, c4978, 10.1136/bmj.c4978 Brand, 2008, Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach, Eur Respir J, 32, 1096, 10.1183/09031936.00002108 Bisgaard, 2009, Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood, Am J Respir Crit Care Med, 179, 179, 10.1164/rccm.200809-1436OC Sorensen, 2007, Biomarkers of exposure to environmental tobacco smoke in infants, Biomarkers, 12, 38, 10.1080/13547500600943148 Knorr, 2001, Montelukast, a leukotriene receptor antagonist, for the treatment of persistent asthma in children aged 2 to 5 years, Pediatrics, 108, e48, 10.1542/peds.108.3.e48 Bacharier, 2008, Episodic use of an inhaled corticosteroid or leukotriene receptor antagonist in preschool children with moderate-to-severe intermittent wheezing, J Allergy Clin Immunol, 122, 1127, 10.1016/j.jaci.2008.09.029 Bisgaard, 1990, Inhaled budesonide for treatment of recurrent wheezing in early childhood, Lancet, 336, 649, 10.1016/0140-6736(90)92147-A Bisgaard, 1999, The effect of inhaled fluticasone propionate in the treatment of young asthmatic children: a dose comparison study, Am J Respir Crit Care Med, 160, 126, 10.1164/ajrccm.160.1.9811024 Smith, 2008, Dimensions of respiratory symptoms in preschool children: population-based birth cohort study, Am J Respir Crit Care Med, 177, 1358, 10.1164/rccm.200709-1419OC Meslier, 1995, Wheezes, Eur Respir J, 8, 1942, 10.1183/09031936.95.08111942 Galanter, 2008, ORMDL3 gene is associated with asthma in three ethnically diverse populations, Am J Respir Crit Care Med, 177, 1194, 10.1164/rccm.200711-1644OC Sears, 2007, Understanding the September asthma epidemic, J Allergy Clin Immunol, 120, 526, 10.1016/j.jaci.2007.05.047 Thomsen, 2010, Genetic influence on the age at onset of asthma: a twin study, J Allergy Clin Immunol, 126, 626, 10.1016/j.jaci.2010.06.017 Bisgaard, 2010, Long-term studies of the natural history of asthma in childhood, J Allergy Clin Immunol, 126, 187, 10.1016/j.jaci.2010.07.011