Prandial increase of leptin in the brain activates spatial learning and memory

Shiraishi, 2000, Effects of leptin and orexin-A on food intake and feeding related hypothalamic neurons, Physiol. Behav., 71, 251, 10.1016/S0031-9384(00)00341-3 Nagamori, 2003, Effects of leptin on hypothalamic arcuate neurons in Wistar and Zucker rats: an in vitro study, Exp. Biol. Med., 228, 1162, 10.1177/153537020322801010 Hwa, 1996, Intracerebroventricular injection of leptin increase thermogenesis and mobilizes fat metabolism in ob/ob mice, Horm. Metab. Res., 28, 639, 10.1055/s-2007-979873 Shanley, 2001, Leptin enhances NMDA receptor function and modulates hippocampal synaptic plasticity, J. Neurosci., 21, 1, 10.1523/JNEUROSCI.21-24-j0001.2001 Oomura, 2006, Leptin facilitates learning and memory performance and enhances hippocampal CA1 long-term potentiation and CaMKII phosphorylation in rats, Peptides, 27, 2738, 10.1016/j.peptides.2006.07.001 Fukunaga, 1993, Long-term potentiation is associated with an increased activity of Ca2+/calmodulin protein kinase II, J. Biol. Chem., 268, 783, 10.1016/S0021-9258(18)53037-4 Manabe, 1998, Facilitation of long-term potentiation and memory in mice lacking nociceptin receptors, Nature, 394, 577, 10.1038/29073 von Heek, 1996, The relationship of tissue localization, distribution and turnover to feeding after intraperitoneal 125I-leptin administration to ob/ob and db/db mice, Horm. Metab. Res., 28, 65 Lisman, 1994, The CaM kinase II hypothesis for the storage of synaptic memory, Trends Neurosci., 17, 406, 10.1016/0166-2236(94)90014-0 Morioka, 1995, Glutamate-induced loss of Ca2+/calmodulin dependent protein kinase II activity cultured rat hippocampal neurons, J. Neurochem., 84, 2132 Li, 2002, Impairment of long-term potentiation and spatial memory in leptin receptor-deficient rodents, Neuroscience, 113, 607, 10.1016/S0306-4522(02)00162-8 Chau, 1996, Phenotypes of mouse diabetes and rat fatty due to mutations in the OB leptin receptor, Science, 271, 994, 10.1126/science.271.5251.994 Phillips, 1996, Leptin receptor missense mutation in the fatty Zucker rat, Nat. Genet., 13, 18, 10.1038/ng0596-18 Hori, 1991, Appeearance of NMDA receptors triggerd by anoxia independent of voltage in vivo and in vitro, Exp. Neurol, 12, 304, 10.1016/0014-4886(91)90131-U Ahima, 1999, Regulation of neuronal and glial proteins by leptin implications for brain development, Endocrinology, 140, 2755, 10.1210/en.140.6.2755 Oyler, 1991, Developmental expression of the 25-kDa synaptosomal-associated protein (SNAP-25) in rat brain, Proc. Natl. Acad. Sci. U.S.A., 88, 5247, 10.1073/pnas.88.12.5247 Behan, 1995, Displacement of corticotrophi factor from its binding protein as a possible treatment for Alzheimer's disease, Nature, 378, 264, 10.1038/378284a0