Recomendaciones sobre el tratamiento de la candidiasis invasiva y otras infecciones por levaduras de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC). Actualización 2011
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Pfaller, 2007, Epidemiology of invasive candidiasis: a persistent public health problem, Clin Microbiol Rev., 20, 133, 10.1128/CMR.00029-06
Almirante, 2005, Epidemiology and predictors of mortality in cases of Candida bloodstream infection: results from population-based surveillance, Barcelona, Spain, from 2002 to 2003, J Clin Microbiol., 43, 1829, 10.1128/JCM.43.4.1829-1835.2005
Bouza, 2008, Epidemiology of candidemia in intensive care units, Int J Antimicrob Agents., 32, S87, 10.1016/S0924-8579(08)70006-2
Marr, 2000, Candidemia in allogeneic blood and marrow transplant recipients: evolution of risk factors after the adoption ofprophylactic fluconazole, J Infect Dis., 181, 309, 10.1086/315193
Sipsas, 2009, Candidemia in patients with hematologic malignancies in the era of new antifungal agents (2001-2007): stable incidence but changing epidemiology of a still frequently lethal infection, Cancer., 115, 4745, 10.1002/cncr.24507
Barnes, 2007, Risks, diagnosis and outcomes of invasive fungal infections in haematopoietic stem cell transplant recipients, Br J Haematol., 139, 519, 10.1111/j.1365-2141.2007.06812.x
Meunier, 2008, The First European Conference on Infections in Leukaemia -ECIL1: a current perspective, Eur J Cancer., 44, 2112, 10.1016/j.ejca.2008.07.008
Böhme, 2009, Treatment of invasive fungal infections in cancer patients--recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO), Ann Hematol., 88, 97, 10.1007/s00277-008-0622-5
Pappas, 2009, Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America, Clin Infect Dis., 48, 503, 10.1086/596757
Anaissie, 1996, Management of invasive candidal infections: results of a prospective, randomized, multicenter study of fluconazole versus amphotericin B and review of the literature, Clin Infect Dis., 23, 964, 10.1093/clinids/23.5.964
Phillips, 1997, Multicenter randomized trial of fluconazole versus amphotericin B for treatment of candidemia in non-neutropenic patients. Canadian Candidemia Study Group, Eur J Clin Microbiol Infect Dis., 16, 337, 10.1007/BF01726360
Rex, 1994, A randomized trial comparing fluconazole with amphotericin B for the treatment of candidemia in patients without neutropenia. Candidemia Study Group and the National Institute, N Engl J Med., 331, 1325, 10.1056/NEJM199411173312001
Kullberg, 2005, Voriconazole versus a regimen of amphotericin B followed by fluconazole for candidaemia in non-neutropenic patients: a randomised non-inferiority trial, Lancet., 366, 1435, 10.1016/S0140-6736(05)67490-9
Mora-Duarte, 2002, Comparison of caspofungin and amphotericin B for invasive candidiasis. Caspofungin Invasive Candidiasis Study Group, N Engl J Med., 347, 2020, 10.1056/NEJMoa021585
Walsh, 2004, Caspofungin versus liposomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia, N Engl J Med., 351, 1391, 10.1056/NEJMoa040446
Kuse, 2007, Micafungin versus liposomal amphotericin B for candidaemia andinvasive candidosis: a phase III randomised double-blind trial, Lancet., 369, 1519, 10.1016/S0140-6736(07)60605-9
Queiroz-Telles, 2008, Micafungin versus liposomal amphotericin B for pediatric patients with invasive candidiasis: substudy of a randomized double-blind trial, Pediatr Infect Dis J., 27, 820, 10.1097/INF.0b013e31817275e6
Pappas, 2007, Micafungin versus caspofungin for treatment of candidemia and other forms of invasive candidiasis, Clin Infect Dis., 45, 883, 10.1086/520980
Reboli, 2007, Anidulafungin versus fluconazole for invasive candidiasis, N Engl J Med., 356, 2472, 10.1056/NEJMoa066906
Ostrosky-Zeichner, 2003, Amphotericin B: time for a new “gold standard”, Clin Infect Dis., 37, 415, 10.1086/376634
Walsh, 1999, Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia. National Institute of Allergy and Infectious Diseases Mycoses Study Group, N Engl J Med, 340, 764, 10.1056/NEJM199903113401004
Rodríguez, 2007, Impact of early central venous catheter removal on outcome in patients with candidaemia, Clin Microbiol Infect., 13, 788, 10.1111/j.1469-0691.2007.01758.x
Raad, 2004, Management of central venous catheters in patients with cancer and candidemia, Clin Infect Dis., 38, 1119, 10.1086/382874
Anaissie, 1991, Fluconazole therapy for chronic disseminated candidiasis in patients with leukemia and prior amphotericin B therapy, Am J Med., 91, 142, 10.1016/0002-9343(91)90006-J
Kauffman, 1991, Hepatosplenic candidiasis: successful treatment with fluconazole, Am J Med. 1, 91, 137, 10.1016/0002-9343(91)90005-I
Gokhale, 1993, Successful treatment of disseminated candidiasis resistant to amphotericin B by liposomal amphotericin B: a case report, J Cancer Res Clin Oncol., 119, 569, 10.1007/BF01372718
Sorà, 2002, Successful treatment with caspofungin of hepatosplenic candidiasis resistant to liposomal amphotericin B, Clin Infect Dis, 35, 1135, 10.1086/343748
Legrand, 2008, Adjuvant corticosteroid therapy for chronic disseminated candidiasis, Clin Infect Dis., 46, 696, 10.1086/527390
Marik, 2006, Fungal infections in solid organ transplantation, Expert Opin Pharmacother., 7, 297, 10.1517/14656566.7.3.297
Pappas, 2010, Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET), Clin Infect Dis., 50, 1101, 10.1086/651262
Kontoyiannis, 2008, Calcineurin inhibitor agents interact synergistically with antifungal agents in vitro against Cryptococcus neoformans isolates: correlation with outcome in solid organ transplant recipients with cryptococcosis, Antimicrob Agents Chemother., 52, 735, 10.1128/AAC.00990-07
Singh, 2007, Cryptococcus neoformans in organ transplant recipients: impact of calcineurin-inhibitor agents on mortality, J Infect Dis., 195, 756, 10.1086/511438
Perfect, 2010, Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of america, Clin Infect Dis., 50, 291, 10.1086/649858
Del Poeta, 2000, Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans, Antimicrob Agents Chemother., 44, 739, 10.1128/AAC.44.3.739-746.2000
Mann, 2009, Impact of antifungal prophylaxis on colonization and azole susceptibility of Candida species, Antimicrob Agents Chemother., 53, 5026, 10.1128/AAC.01031-09
Singh, 2008, Antifungal management practices in liver transplant recipients, Am J Transplant., 8, 426, 10.1111/j.1600-6143.2007.02089.x
Pappas, 2006, Invasive fungal infections in low-risk liver transplant recipients: a multi-center prospective observational study, Am J Transplant., 6, 386, 10.1111/j.1600-6143.2005.01176.x
Fortun, 2009, Prophylaxis with caspofungin for invasive fungal infections in high-risk liver transplant recipients, Transplantation., 87, 424, 10.1097/TP.0b013e3181932e76
Singh, 2005, Antifungal management practices and evolution of infection in organ transplant recipients with Cryptococcus neoformans infection, Transplantation., 80, 1033, 10.1097/01.tp.0000173774.74388.49
Baddour, 2005, Successful use of amphotericin B lipid complex in the treatment of cryptococcosis, Clin Infect Dis., 40, S409, 10.1086/429337
Barrett, 2003, A systematic review of the antifungal effectiveness and tolerability of amphotericin B formulations, Clin Ther., 25, 1295, 10.1016/S0149-2918(03)80125-X
Sun, 2009, Lipid formulations of amphotericin B significantly improve outcome in solid organ transplant recipients with central nervous system cryptococcosis, Clin Infect Dis., 49, 1721, 10.1086/647948
Schwarz, 2006, Efficacy of amphotericin B in combination with flucytosine against flucytosine-susceptible or flucytosine-resistant isolates of Cryptococcus neoformans during disseminated murine cryptococcosis, Antimicrob Agents Chemother., 50, 113, 10.1128/AAC.50.1.113-120.2006
Brouwer, 2004, Combination antifungal therapies for HIV-associated cryptococcal meningitis: a randomised trial, Lancet., 363, 1764, 10.1016/S0140-6736(04)16301-0
van der Horst, 1997, Treatment of cryptococcal meningitis associated with the acquired immunodeficiency syndrome. National Institute of Allergy and Infectious Diseases Mycoses Study Group and AIDS Clinical Trials Group, N Engl J Med., 337, 15, 10.1056/NEJM199707033370103
Bicanic, 2008, High-dose amphotericin B with flucytosine for the treatment of cryptococcal meningitis in HIV-infected patients: a randomized trial, Clin Infect Dis., 47, 123, 10.1086/588792
Dromer, 2008, Major role for amphotericin B-flucytosine combination in severe cryptococcosis, PLoS One., 3, e2870, 10.1371/journal.pone.0002870
Allendoerfer, 1991, Combined therapy with fluconazole and flucytosine in murine cryptococcal meningitis, Antimicrob Agents Chemother., 35, 726, 10.1128/AAC.35.4.726
Bava, 1994, Flucytosine+fluconazole association in the treatment of a murine experimental model of cryptococcosis, Rev Inst Med Trop Sao Paulo., 36, 551, 10.1590/S0036-46651994000600013
Bicanic, 2009, Relationship of cerebrospinal fluid pressure, fungal burden and outcome in patients with cryptococcal meningitis undergoing serial lumbar punctures, AIDS., 23, 701, 10.1097/QAD.0b013e32832605fe
Liliang, 2002, Use of ventriculoperitoneal shunts to treat uncontrollable intracranial hypertension in patients who have cryptococcal meningitis without hydrocephalus, Clin Infect Dis., 34, E64, 10.1086/340525
Graybill, 2000, Diagnosis and management of increased intracranial pressure in patients with AIDS and cryptococcal meningitis. The NIAID Mycoses Study Group and AIDS Cooperative Treatment Groups, Clin Infect Dis., 30, 47, 10.1086/313603
Chin, 1990, Pharmacokinetics of fluconazole in serum and cerebrospinal fluid in a patient with AIDS and cryptococcal meningitis, Pharmacotherapy., 10, 305
Nagappan, 2007, Reviews of anti-infective agents: posaconazole: a broad-spectrum triazole antifungal agent, Clin Infect Dis., 45, 1610, 10.1086/523576
Bandettini, 2009, Voriconazole for cryptococcal meningitis in children with leukemia or receiving allogeneic hemopoietic stem cell transplant, J Chemother., 21, 108, 10.1179/joc.2009.21.1.108
Sun, 2009, Cryptococcosis in solid-organ, hematopoietic stem cell, and tissue transplant recipients: evidence-based evolving trends, Clin Infect Dis., 48, 1566, 10.1086/598936
Singh, 2005, An immune reconstitution syndrome-like illness associated with Cryptococcus neoformans infection in organ transplant recipients, Clin Infect Dis., 40, 1756, 10.1086/430606
Singh, 2005, Allograft loss in renal transplant recipients with Cryptococcus neoformans associated immune reconstitution syndrome, Transplantation., 80, 1131, 10.1097/01.tp.0000180530.17683.02
Pérez-Parra, 2009, Is Candida colonization of central vascular catheters in non-candidemic, non-neutropenic patients an indication for antifungals?, Intensive Care Med., 35, 707, 10.1007/s00134-009-1431-6
Saag, 2000, Practice guidelines for the management of cryptococcal disease. Infectious Diseases Society of America, Clin Infect Dis., 30, 710, 10.1086/313757
Jarvis, 1995, Epidemiology of nosocomial fungal infections, with emphasis on Candida species, Clin Infect Dis., 20, 1526, 10.1093/clinids/20.6.1526
Vincent, 2009, International Study of the Prevalence and Outcomes of Infection in Intensive Care Units, JAMA., 302, 2323, 10.1001/jama.2009.1754
Eggimann, 2003, Epidemiology of Candida species infections in critically ill non-immunosuppressed patients, Lancet Infect Dis., 3, 685, 10.1016/S1473-3099(03)00801-6
León, 2009, Fungal colonization and/or infection in non-neutropenic critically ill patients: results of the EPCAN observational study, Eur J Clin Microbiol Infect Dis., 28, 233, 10.1007/s10096-008-0618-z
León, 2009, Usefulness of the “Candida score” for discriminating between Candida colonization and invasive candidiasis in non-neutropenic critically ill patients: a prospective multicenter study, Crit Care Med., 37, 1624, 10.1097/CCM.0b013e31819daa14
Leroy, 2009, Epidemiology, management, and risk factors for death of invasive Candida infections in critical care: A multicenter, prospective, observational study in France (2005-2006), Crit Care Med., 37, 1612, 10.1097/CCM.0b013e31819efac0
Marriott, 2009, Determinants of mortality in non-neutropenic ICU patients with candidaemia, Critical Care., 13, R115, 10.1186/cc7964
Holley, 2009, Temporal trends, risk factors and outcomes in albicans and non-albicans candidaemia: an international epidemiological study in four multidisciplinary intensive care units, Int J Antimicrob Agents., 33, 554.e1, 10.1016/j.ijantimicag.2008.10.035
Eggimann, 1999, Fluconazole prophylaxis prevents intra-abdominal candidiasis in high-risk surgical patients, Crit Care Med., 27, 1066, 10.1097/00003246-199906000-00019
Pelz, 2001, Double-blind placebo-controlled trial of fluconazole to prevent candidal infections in critically ill surgical patients, Ann Surg., 233, 542, 10.1097/00000658-200104000-00010
Garbino, 2002, Prevention of severe Candida infections in nonneutropenic, high-risk, critically ill patients: a randomized, double-blind, placebo-controlled trial in patients treated by selective digestive decontamination, Intensive Care Med., 28, 1708, 10.1007/s00134-002-1540-y
Piarroux, 2004, Assessment of preemptive treatment to prevent severe candidiasis in critically ill surgical patients, Crit Care Med., 32, 2443, 10.1097/01.CCM.0000147726.62304.7F
Cruciani, 2005, Prophylaxis of Candida infections in adult trauma and surgical intensive care patients: a systematic review and meta-analysis, Intensive Care Med., 31, 1479, 10.1007/s00134-005-2794-y
Playford, 2006, Antifungal agents for preventing fungal infections in non-neutropenic critically ill and surgical patients: systematic review and meta-analysis of randomized clinical trials, J Antimicrob Chemother., 57, 628, 10.1093/jac/dki491
Vardakas, 2006, Antifungal prophylaxis with azoles in high-risk, surgical intensive care unit patients: a meta-analysis of randomized, placebo-controlled trials, Crit Care Med., 34, 1216, 10.1097/01.CCM.0000208357.05675.C3
Pittet, 1994, Candida colonization and subsequent infections in critically ill surgical patients, Ann Surg., 220, 751, 10.1097/00000658-199412000-00008
Rex, 1994, A Randomized Trial Comparing Fluconazole with Amphotericin B for the Treatment of Candidemia in Patients without Neutropenia, N Engl J Med., 331, 1325, 10.1056/NEJM199411173312001
DiNubile, 2007, Invasive candidiasis treated in the intensive care unit: Observations from a randomized clinical trial, J Crit Care., 22, 237, 10.1016/j.jcrc.2006.11.004
Hsu, 2010, A multicentre study to evaluate the impact of timing of caspofungin administration on outcomes of invasive candidiasis in non-immunocompromised adult patients, J Antimicrob Chemother., 65, 1765, 10.1093/jac/dkq216
Ortega, 2010, Candida spp. bloodstream infection: influence of antifungal treatment on outcome, J Antimicrob Chemother., 65, 562, 10.1093/jac/dkp495
Magill, 2006, Triazole Cross-Resistance among Candida spp.: Case Report, Occurrence among Bloodstream Isolates, and Implications for Antifungal Therapy, J Clin Microbiol., 44, 529, 10.1128/JCM.44.2.529-535.2006
Nolla-Salas, 1997, Candidemia in non-neutropenic critically ill patients: analysis of prognostic factors and assessment of systemic antifungal therapy. Study Group of Fungal Infection in the ICU, Intensive Care Med., 23, 23, 10.1007/s001340050286
Morrell, 2005, Delaying the empiric treatment of candida bloodstream infection until positive blood culture results are obtained: a potential risk factor for hospital mortality, Antimicrob Agents Chemother., 49, 3640, 10.1128/AAC.49.9.3640-3645.2005
Garey, 2006, Time to initiation of fluconazole therapy impacts mortality in patients with candidemia: a multi-institutional study, Clin Infect Dis., 43, 25, 10.1086/504810
Parkins, 2007, Adequacy of empirical antifungal therapy and effect on outcome among patients with invasive Candida species infections, J Antimicrob Chemother., 60, 613, 10.1093/jac/dkm212
Fridkin, 2006, Changing incidence of Candida bloodstream infections among NICU patients in the United States: 1995-2004, Pediatrics., 117, 1680, 10.1542/peds.2005-1996
Stoll, 2002, Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network, Pediatrics., 110, 285, 10.1542/peds.110.2.285
Saiman, 2001, Risk factors for Candida species colonization of neonatal intensive care unit patients, Pediatr Infect Dis J., 20, 1119, 10.1097/00006454-200112000-00005
Chapman, 2003, Candida infections in the neonate, Curr Opin Pediatr., 15, 97, 10.1097/00008480-200302000-00016
Rodríguez, 2006, Candidemia in neonatal intensive care units: Barcelona, Spain. Pediatr Infect Dis J., 25, 224, 10.1097/01.inf.0000202127.43695.06
López Sastre, 2003, Neonatal invasive candidiasis: a prospective multicenter study of 118 cases, Am J Perinatol., 20, 153, 10.1055/s-2003-40008
Fernández, 2000, Candidal meningitis in neonates: a 10-year review, Clin Infect Dis., 31, 458, 10.1086/313973
Cotten, 2006, The association of third-generation cephalosporin use and invasive candidiasis in extremely low birth-weight infants, Pediatrics., 118, 717, 10.1542/peds.2005-2677
Kaufman, 2006, Patterns of fungal colonization in preterm infants weighing less than 1000 grams at birth, Pediatr Infect Dis J., 25, 733, 10.1097/01.inf.0000226978.96218.e6
Saiman, 2000, Risk factors for candidemia in Neonatal Intensive Care Unit patients. The National Epidemiology of Mycosis Survey study group, Pediatr Infect Dis J., 19, 319, 10.1097/00006454-200004000-00011
Benjamin, 2006, Neonatal candidiasis among extremely low birth weight infants: risk factors, mortality rates, and neurodevelopmental outcomes at 18 to 22 months, Pediatrics., 117, 84, 10.1542/peds.2004-2292
Karlowicz, 2000, Should central venous catheters be removed as soon as candidemia is detected in neonates?, Pediatrics., 106, E63, 10.1542/peds.106.5.e63
Chapman, 2000, Persistently positive cultures and outcome in invasive neonatal candidiasis, Pediatr Infect Dis J., 19, 822, 10.1097/00006454-200009000-00003
Steinbach, 2005, Antifungal agents in children, Pediatr Clin North Am., 52, 895, 10.1016/j.pcl.2005.02.009
Almirante, 2007, Antifungal agents in neonates: issues and recommendations, Paediatr Drugs., 9, 311, 10.2165/00148581-200709050-00004
American Academy of Pediatrics. Candidiasis. En: Pickering, L.K., editor. Red Book: 2009 Report of the Committee on Infectious Diseases. Elk Grove Village, IL: American Academy of Pediatrics; 2009.p.245-253.
Pappas, 2009, Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America, Clin Infect Dis., 48, 503, 10.1086/596757
Hall, 1987, Amphotericin B dosage for disseminated candidiasis in premature infants, J Perinatol., 7, 194
Starke, 1987, Pharmacokinetics of amphotericin B in infants and children, J Infect Dis., 155, 766, 10.1093/infdis/155.4.766
Baley, 1990, Pharmacokinetics, outcome of treatment, and toxic effects of amphotericin B and 5-fluorocytosine in neonates, J Pediatr., 116, 791, 10.1016/S0022-3476(05)82674-5
Rowen, 1998, Management of neonatal candidiasis. Neonatal Candidiasis Study Group, Pediatr Infect Dis J., 17, 1007, 10.1097/00006454-199811000-00008
Butler, 1990, Amphotericin B as a single agent in the treatment of systemic candidiasis in neonates, Pediatr Infect Dis J., 9, 51, 10.1097/00006454-199001000-00012
Walsh, 1997, Safety, tolerance, and pharmacokinetics of amphotericin B lipid complex in children with hepatosplenic candidiasis, Antimicrob Agents Chemother., 41, 1944, 10.1128/AAC.41.9.1944
Walsh, 1999, Amphotericin B lipid complex in pediatric patients with invasive fungal infections, Pediatr Infect Dis J., 18, 702, 10.1097/00006454-199908000-00010
Scarcella, 1998, Liposomal amphotericin B treatment for neonatal fungal infections, Pediatr Infect Dis J., 17, 146, 10.1097/00006454-199802000-00013
Juster-Reicher, 2003, High-dose liposomal amphotericin B in the therapy of systemic candidiasis in neonates, Eur J Clin Microbiol Infect Dis., 22, 603, 10.1007/s10096-003-0993-4
Lee, 1992, Safety and pharmacokinetics of fluconazole in children with neoplastic diseases, J Pediatr., 120, 987, 10.1016/S0022-3476(05)81975-4
Saxen, 1993, Pharmacokinetics of fluconazole in very low birth weight infants during the first two weeks of life, Clin Pharmacol Ther., 54, 269, 10.1038/clpt.1993.147
Seay, 1995, Pharmacokinetics of fluconazole in immune-compromised children with leukemia or other hematologic diseases, Pharmacotherapy., 15, 52
Wade, 2008, Population pharmacokinetics of fluconazole in young infants, Antimicrob Agents Chemother., 52, 4043, 10.1128/AAC.00569-08
Wade, 2009, Fluconazole dosing for the prevention or treatment of invasive candidiasis in young infants, Pediatr Infect Dis J., 28, 717, 10.1097/INF.0b013e31819f1f50
Driessen, 1996, Fluconazole vs. amphotericin B for the treatment of neonatal fungal septicemia: a prospective randomized trial, Pediatr Infect Dis J., 15, 1107, 10.1097/00006454-199612000-00011
Linder, 2003, Treatment of candidaemia in premature infants: comparison of three amphotericin B preparations, J Antimicrob Chemother., 52, 663, 10.1093/jac/dkg419
Würthwein, 2005, Population pharmacokinetics of amphotericin B lipid complex in neonates, Antimicrob Agents Chemother., 49, 5092, 10.1128/AAC.49.12.5092-5098.2005
Steinbach, 2005, New antifungal agents under development in children and neonates, Curr Opin Infect Dis., 18, 484, 10.1097/01.qco.0000185986.64759.9a
Seibel, 2005, Safety, tolerability, and pharmacokinetics of Micafungin (FK463) in febrile neutropenic pediatric patients, Antimicrob Agents Chemother., 49, 3317, 10.1128/AAC.49.8.3317-3324.2005
Heresi, 2006, The pharmacokinetics and safety of micafungin, a novel echinocandin, in premature infants, Pediatr Infect Dis J., 25, 1110, 10.1097/01.inf.0000245103.07614.e1
Benjamin, 2006, Safety and pharmacokinetics of intravenous anidulafungin in children with neutropenia at high risk for invasive fungal infections, Antimicrob Agents Chemother., 50, 632, 10.1128/AAC.50.2.632-638.2006
Smith, 2009, Pharmacokinetics of an elevated dosage of micafungin in premature neonates, Pediatr Infect Dis J., 28, 412, 10.1097/INF.0b013e3181910e2d
Zaoutis, 2005, The epidemiology and attributable outcomes of candidemia in adults and children hospitalized in the United States: A propensity analysis, Clin Infect Dis., 41, 1232, 10.1086/496922
Stamos, 1995, Candidemia in a pediatric population, Clin Infect Dis., 20, 571, 10.1093/clinids/20.3.571
Blyth, 2009, Not just little adults: candidemia epidemiology, molecular characterization, and antifungal susceptibility in neonatal and pediatric patients, Pediatrics., 123, 1360, 10.1542/peds.2008-2055
Celebi, 2008, Nosocomial candidaemia in children: results of a 9-year study, Mycoses., 51, 248, 10.1111/j.1439-0507.2007.01464.x
Prasad, 2008, Pediatric antifungal utilization: new drugs, new trends, Pediatr Infect Dis J., 27, 1083, 10.1097/INF.0b013e31817eeee5
Blyth, 2007, Antifungal therapy in children witn invasive fungal infections: a systematic review, Pediatrics., 119, 772, 10.1542/peds.2006-2931
Walsh, 2004, Pharmacokinetics and safety of intravenous voriconazole in children after single- or multiple-dose administration, Antimicrob Agents Chemother., 48, 2166, 10.1128/AAC.48.6.2166-2172.2004
Karlsson, 2009, Population pharmacokinetic analysis of voriconazole plasma concentration data from pediatric studies, Antimicrob Agents Chemother., 53, 935, 10.1128/AAC.00751-08
Neeley, 2010, Voriconazole pharmacokinetics and pharmacodynamics in children, Clin Infect Dis., 50, 27, 10.1086/648679
Fisher, 2008, Caspofungin for the treatment of pediatric fungal infections, Pediatr Infect Dis J., 27, 1099, 10.1097/INF.0b013e3181937fe0
Zaoutis, 2009, A prospective, multicenter study of caspofungin for the treatment of documented Candida or Aspergillus infections in pediatric patients, Pediatrics., 123, 877, 10.1542/peds.2008-1158
Queiroz-Telles, 2008, Micafungin versus liposomal amphotericin B for pediatric patients with invasive candidiasis: substudy of a randomized double-blind trial, Pediatr Infect Dis J., 27, 820, 10.1097/INF.0b013e31817275e6
Blyth, 2007, Antifungal therapy in children with invasive fungal infections: a systematic review, Pediatrics., 119, 772, 10.1542/peds.2006-2931
Presterl, 1994, Efficacy and safety of fluconazole in the treatment of systemic fungal infections in pediatric patients. Multicentre Study Group, Eur J Clin Microbiol Infect Dis., 13, 347, 10.1007/BF01974618
Schwarze, 2000, Treatment of candidal infections with fluconazole in neonates and infants, Eur J Med Res., 5, 203
Odio, 2004, Caspofungin therapy of neonates with invasive candidiasis, Pediatr Infect Dis J., 23, 1093, 10.1097/01.inf.0000145408.51526.0a
Merlin, 2006, Efficacy and safety of caspofungin therapy in children with invasive fungal infections, Pediatr Infect Dis J., 25, 1186, 10.1097/01.inf.0000246844.42159.a0
Koo, 2007, Efficacy and safety of caspofungin for the empiric management of fever in neutropenic children, Pediatr Infect Dis J., 26, 854, 10.1097/INF.0b013e318067b4d1
Pasqualotto, 2008, Voriconazole plasma monitoring, Arch Dis Child., 93, 578, 10.1136/adc.2007.118844
Maertens, 2010, A randomized, double-blind, multicenter study of caspofungin versus liposomal amphotericin B for empiric antifungal therapy in pediatric patients with persistent fever and neutropenia, Pediatr Infect Dis J., 29, 415, 10.1097/INF.0b013e3181da2171
Gonzalez, 1996, Cryptococcosis in human immunodeficiency virus-infected children, Pediatr Infect Dis J., 15, 796, 10.1097/00006454-199609000-00012
Sirinavin, 2004, Mother-to-child transmission of cryptococcus neoformans, Pediatr Infect Dis J., 23, 278, 10.1097/01.inf.0000115639.43305.9b
Manfredi, 1997, Liposomal amphotericin B and recombinant human granulocyte-macrophage colony-stimulating factor (rHuGM-CSF) in the treatment of paediatric AIDS-related cryptococcosis, Int J STD AIDS., 8, 406, 10.1258/0956462971920226
Wiley, 2005, Efficacy and safety of amphotericin B lipid complex in 548 children and adolescents with invasive fungal infections, Pediatr Infect Dis J., 24, 167, 10.1097/01.inf.0000153183.51258.b8
Perfect, 2010, Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the Infectious Diseases Society of America, Clin Infect Dis., 50, 291, 10.1086/649858
Pfaller, 2004, Rare and emerging opportunistic fungal pathogens: concern for resistance beyond Candida albicans and Aspergillus fumigatus, J Clin Microbiol., 42, 4419, 10.1128/JCM.42.10.4419-4431.2004
Girmenia, 2005, Invasive infections caused by Trichosporon species and Geotrichum capitatum in patients with hematological malignancies: a restropective multicenter study from Italy and review of the literature, J Clin Microbiol., 43, 1818, 10.1128/JCM.43.4.1818-1828.2005
Moretti-Branchini, 2001, Trichosporon species infection in bone marrow transplanted patients, Diagnost Microbiol Infect Dis., 39, 161, 10.1016/S0732-8893(01)00215-2
Asada, 2006, Succesful treatment of breakthrough Trichosporon ashaii fungemia with voriconazole in a patient with acute myeloid leukemia, Clin Infect Dis., 43, e39, 10.1086/505970
Moylett, 2003, Trichosporon pullulans infection in 2 patientes with chronic granulomatous disease: an emerging pathogen and review of the literature, J Allergy Clin Immnunol., 111, 1370, 10.1067/mai.2003.1522
Serena, 2006, Efficacy of voriconazole in a guinea pig model of invasive trichosporonosis, Antimicrob Agents Chemother., 50, 2240, 10.1128/AAC.00045-06
Antachopoulos, 2005, Fungemia due Trichosporon asahii in a neutropenic child refractary to amphoteriocin B. Clearance with voriconazole, J Pediatr Hematol Oncol., 27, 283, 10.1097/01.mph.0000164865.70522.d7