Inhibition of Pulmonary Surfactant Adsorption by Serum and the Mechanisms of Reversal by Hydrophilic Polymers: Theory

Clements, 1998, Lung surfactant and neonatal respiratory distress syndrome, Am. J. Respir. Crit. Care Med., 157, 59, 10.1164/ajrccm.157.4.nhlb1-1 Notter, 2000 Lu, 2000, Polymer-surfactant treatment of meconium-induced acute lung injury, Am. J. Respir. Crit. Care Med., 162, 623, 10.1164/ajrccm.162.2.9909099 Tashiro, 2000, Dextran reduces surfactant inhibition by meconium, Acta Paediatr., 89, 1439, 10.1111/j.1651-2227.2000.tb02773.x Tashiro, 2003, Modified protocols for surfactant therapy in experimental meconium aspiration syndrome, Biol. Neonate, 83, 49, 10.1159/000067009 Holm, 1988, A biophysical mechanism by which plasma proteins inhibit lung surfactant activity, Chem. Phys. Lipids, 1988, 49, 10.1016/0009-3084(88)90063-1 Hyers, 1991, Adult respiratory distress syndrome: definition, risk factors and outcome, 23 Spragg, R. J., and R. M. Smith. 1998. Surfactant replacement in patients with ARDS: result of clinical trials. In Acute Respiratory Distress Syndrome: Cellular and Molecular Mechanisms and Clinical Management. S. Matalon, J. I. Sznajder, and North Atlantic Treaty Organization Scientific Division, editors. Plenum Press, New York, NY. 107–116. Spragg, 1991, Abnormalities of lung surfactant function in patients with acute lung injury, 381 Nakos, 1998, Bronchoalveolar lavage fluid characteristics of early intermediate and late phases of ARDS. Alterations in leukocytes, proteins, PAF and surfactant components, Intensive Care Med., 24, 296, 10.1007/s001340050571 Hallman, 2001, Surfactant in respiratory distress syndrome and lung injury, Comp. Biochem. Phys. A Mol. Integr. Physiol., 129, 287, 10.1016/S1095-6433(01)00324-5 Warriner, 2002, A concentration-dependent mechanism by which serum albumin inactivates replacement lung surfactants, Biophys. J., 82, 835, 10.1016/S0006-3495(02)75445-3 Anzueto, 2002, Exogenous surfactant in acute respiratory distress syndrome: more is better, Eur. Respir. J., 19, 787, 10.1183/09031936.02.00284902 Guenther, 2002, Bronchoscopic administration of bovine natural surfactant in ARDS and septic shock: impact on biophysical and biochemical surfactant properties, Eur. Respir. J., 19, 797, 10.1183/09031936.02.00243302 Wiswell, 1999, ATBronchopulmonary segmental lavage with Surfaxin (KL4-surfactant) for acute respiratory distress syndrome, Am. J. Respiratory and Critical Care Medicine, 160, 10.1164/ajrccm.160.4.9808118 Taeusch, 1999, Hydrophilic polymers added to surfactant enhance treatment of lung injury by reducing surfactant inactivation, Am. J. Respir. Crit. Care Med., 159, A595 Lu, 2003, The effect of concentration on the bulk adsorption of bovine lipid extract surfactant, Colloids Surf. B, 29, 119, 10.1016/S0927-7765(02)00161-3 Lu, 2002, The effect of dextran to restore the activity of pulmonary surfactant inhibited by albumin, Respir. Physiol. Neurobiol., 130, 169, 10.1016/S0034-5687(02)00006-3 Lu, 2001, Polyethylene glycol/surfactant mixtures improve lung function after HCl and endotoxin lung injuries, Am. J. Respir. Crit. Care Med., 164, 1531, 10.1164/ajrccm.164.8.2104016 Lu, 1999, Hydrophilic polymers prevent surfactant inactivation, J. Invest. Med., 47, 32A Taeusch, 2000, Treatment of acute (adult) respiratory distress syndrome: the holy grail of surfactant therapy, Biol. Neonate, 77, 2, 10.1159/000047050 Yu, 2004, Polyethylene glycol enhances the surface activity of a pulmonary surfactant, Colloids Surf. B Biointerfaces, 36, 167, 10.1016/j.colsurfb.2004.06.005 Kobayashi, 1999, Dextran restores albumin-inhibited surface activity of pulmonary surfactant extract, J. Appl. Physiol., 86, 1778, 10.1152/jappl.1999.86.6.1778 Dinsmore, 1996, Entropic control of particle motion using passive surface microstructures, Nature, 383, 239, 10.1038/383239a0 Dinsmore, 1998, Hard spheres in vesicles: curvature-induced forces and particle induced curvature, Phys. Rev. Lett., 80, 409, 10.1103/PhysRevLett.80.409 Hiemenz, 1986 Krishnan, 2003, Scaled interfacial activity of proteins at the liquid-vapor interface, J. Biomed. Mater. Res., 68A, 544, 10.1002/jbm.a.20104 Walters, 2000, Distinct steps in the adsorption of pulmonary surfactant to an air-liquid interface, Biophys. J., 78, 257, 10.1016/S0006-3495(00)76589-1 Alig, 2004, Electrostatic barrier to recovery of DPPG monolayers after collapse, Biophys. J., 86, 897, 10.1016/S0006-3495(04)74165-X Kaplan, 1994, Entropically driven surface phase separation in binary colloidal mixtures, Phys. Rev. Lett., 72, 582, 10.1103/PhysRevLett.72.582 Mondain-Monval, 1995, Depletion forces in the presence of electrostatic double layer repulsion, Phys. Rev. Lett., 75, 3364, 10.1103/PhysRevLett.75.3364 Bickel, 2003, Depletion forces near a soft interface, J. Chem. Phys., 118, 8960, 10.1063/1.1568732 Israelachvili, 1992 McClellan, 2003, Effect of concentration and denaturation on adsorption and surface tension of bovine serum albumin, Colloids Surf. B, 28, 63, 10.1016/S0927-7765(02)00131-5 Phang, 2004, Dynamic adsorption and surface tension of aqueous dilauroylphosphatidylcholine dispersions under physiological conditions, Langmuir, 20, 4004, 10.1021/la035424w Holm, 1999, Multiple mechanisms of lung surfactant inhibition, Pediatr. Res., 46, 85, 10.1203/00006450-199907000-00015 Haller, 2004, Tracing surfactant transformation from cellular release to insertion into an air-liquid interface, Am. J. Physiol. Lung Cell. Mol. Physiol., 286, L1009, 10.1152/ajplung.00342.2003 Lipp, 1998, Coexistence of buckled and flat monolayers, Phys. Rev. Lett., 81, 1650, 10.1103/PhysRevLett.81.1650 Diamant, 2000, Unstable topography of biphasic surfactant monolayers, Europhys. Lett., 52, 171, 10.1209/epl/i2000-00419-1 Lu, 2002, Folding Langmuir monolayers, Phys. Rev. Lett., 89, 146107, 10.1103/PhysRevLett.89.146107 Mbagwu, 1999, Sensitivity of synthetic surfactants to albumin inhibition in preterm rabbits, Mol. Genet. Metab., 66, 40, 10.1006/mgme.1998.2788 Diemel, 2002, vitro and in vivo intrapulmonary distribution of fluorescently labelled surfactant, Crit. Care Med., 30, 1083, 10.1097/00003246-200205000-00020 Ding, 2003, Nanostructure changes in lung surfactant monolayers induced by interactions between POPG and SP-B, Langmuir, 19, 1539, 10.1021/la0261794 Ding, 2001, Effects of lung surfactant proteins, SP-B and SP-C, and palmitic acid on monolayer stability, Biophys. J., 80, 2262, 10.1016/S0006-3495(01)76198-X Hu, 2004, Synergistic interactions of lipids and myelin basic proteins, Proc. Natl. Acad. Sci. USA, 101, 13466, 10.1073/pnas.0405665101 Evans, 1994 Schürch, 1998, Formation and structure of surface films: captive bubble surfactometry, Biochim. Biophys. Acta, 1408, 180, 10.1016/S0925-4439(98)00067-2 Kobayashi, 2001, Experimental models of acute respiratory distress syndrome: clinical relevance and response to surfactant therapy, Biol. Neonate, 80, 26, 10.1159/000047174 Cui, 2003, Aerosolized surfactant and dextran for experimental acute respiratory distress syndrome caused by acidified milk in rats, Acta Anaethesiol. Scand., 47, 853, 10.1034/j.1399-6576.2003.00168.x Dehority, W., K. W. Lu, J. A. Clements, J. Goerke, and H. W. Taeusch. 2005. Polymer-surfactant therapy for adult rats with acute lung injury induced by saline lavage. Pediatr. Res. In press. Dehority, 2001, Increased lung water may affect responses to treatment of acute lung injury in rats with polymer-surfactant mixtures, Am. J. Respir. Crit. Care Med., 163, A81 Bhat, 1992, Steric exclusion is the principle source of the preferential hydration of proteins in the presence of polyethylene glycols, Protein Sci., 1, 1133, 10.1002/pro.5560010907 Braun, 2004 Ishizaka, 2004, Elevation of KL-6, a lung epithelial cell marker, in plasma and epithelial lining fluid in ARDS, Am. J. Physiol. Lung Cell. Mol. Physiol., 286, L1088, 10.1152/ajplung.00420.2002