Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis

PLoS ONE - Tập 11 Số 2 - Trang e0148142
Paula Giselle Czaikoski1, José Maurício Mota2, Daniele C. Nascimento3, Fabiane Sônego1, Fernanda V. S. Castanheira1, Paulo H. Melo3, Gabriela Trentin Scortegagna3, Rangel L. Silva1, Romualdo Barroso‐Sousa2, Fabrício Oliveira Souto3, Antônio Pazin‐Filho2, Florêncio Figueiredo4, José C. Alves‐Filho1, Fernando Q. Cunha1
1Department of Pharmacology, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil
2Department of Clinics, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil
3Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil
4Department of Pathology, School of Medicine, University of Brasilia, Brasilia, Brazil

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RC Bone, 1992, Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine, Chest, 101, 1644, 10.1378/chest.101.6.1644

DG Remick, 2007, Pathophysiology of sepsis, Am J Pathol., 170, 1435, 10.2353/ajpath.2007.060872

F Bachelerie, 2014, International Union of Pharmacology. LXXXIX. Update on the Extended Family of Chemokine Receptors and Introducing a New Nomenclature for Atypical Chemokine Receptors, Pharmacol Rev, 66, 1, 10.1124/pr.113.007724

C Canetti, 2001, Tumour necrosis factor-alpha and leukotriene B4 mediate the neutrophil migration in immune inflammation, Br J Pharmacol., 134, 1619, 10.1038/sj.bjp.0704403

MJ Kaplan, 2012, Neutrophil extracellular traps: double-edged swords of innate immunity, J Immunol., 189, 2689, 10.4049/jimmunol.1201719

WC Aird, 2003, The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome, Blood., 101, 3765, 10.1182/blood-2002-06-1887

T Gustot, 2011, Multiple organ failure in sepsis: prognosis and role of systemic inflammatory response, Curr Opin Crit Care, 17, 153, 10.1097/MCC.0b013e328344b446

RS Hotchkiss, 2003, The pathophysiology and treatment of sepsis, N Engl J Med, 348, 138, 10.1056/NEJMra021333

LM Hoesel, 2005, Harmful and protective roles of neutrophils in sepsis, Shock., 24, 40, 10.1097/01.shk.0000170353.80318.d5

V Brinkmann, 2004, Neutrophil extracellular traps kill bacteria, Science, 303, 1532, 10.1126/science.1092385

AB Guimarães-Costa, 2009, Leishmania amazonensis promastigotes induce and are killed by neutrophil extracellular traps, Proc Natl Acad Sci USA., 106, 6748, 10.1073/pnas.0900226106

CF Urban, 2006, Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms, Cell Microbiol, 8, 668, 10.1111/j.1462-5822.2005.00659.x

M Bianchi, 2009, Restoration of NET formation by gene therapy in CGD controls aspergillosis, Blood, 114, 2619, 10.1182/blood-2009-05-221606

TA Fuchs, 2007, Novel cell death program leads to neutrophil extracellular traps, J Cell Biol., 176, 231, 10.1083/jcb.200606027

M Bianchi, 2011, Restoration of anti-Aspergillus defense by neutrophil extracellular traps in human chronic granulomatous disease after gene therapy is calprotectin-dependent, J Allergy Clin Immunol., 127, 1243, 10.1016/j.jaci.2011.01.021

RL Young, 2011, Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR, PLoS One, 6, e23637, 10.1371/journal.pone.0023637

TA Fuchs, 2010, Extracellular DNA traps promote thrombosis, Proc Natl Acad Sci USA., 107, 15880, 10.1073/pnas.1005743107

A Caudrillier, 2012, Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury, J Clin Invest., 122, 2661, 10.1172/JCI61303

T Narasaraju, 2011, Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis, Am J Pathol., 179, 199, 10.1016/j.ajpath.2011.03.013

E Villanueva, 2011, Netting neutrophils induce endotelial damage, infiltrate tissues and expose immunostimulatory molecules in systemic lupus erythematosus, J Immunol, 187, 538, 10.4049/jimmunol.1100450

A Hakkim, 2010, Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis, Proc Natl Acad Sci USA., 107, 9813, 10.1073/pnas.0909927107

K Kessenbrock, 2009, Netting neutrophils in autoimmune small-vessel vasculitis, Nat Med., 15, 623, 10.1038/nm.1959

SL Wong, 2015, Diabetes primes neutrophils to undergo NETosis, which impairs wound healing, Nat Med, 21, 815, 10.1038/nm.3887

F Fattahi, 2015, Organ distribution of histones after intravenous infusion of FITC histones or after sepsis, Immunol Res, 61, 177, 10.1007/s12026-015-8628-2

K Tanaka, 2014, In vivo characterization of neutrophil extracellular traps in various organs of a murine sepsis model, PLoS One, 9, e111888, 10.1371/journal.pone.0111888

M Hashiba, 2015, Neutrophil extracellular traps in patients with sepsis, J Surg Res, 194, 248, 10.1016/j.jss.2014.09.033

K Martinod, 2015, PAD4-deficiency does not affect bacteremia in polymicrobial sepsis and ameliorates endotoxemic shock, Blood, 125, 1948, 10.1182/blood-2014-07-587709

MM Levy, 2003, SCCM/ESICM/ACCP/ATS/SIS. 2001 SCCM/ESICM/ ACCP/ATS/SIS international sepsis definitions conference, Crit Care Med, 31, 1250, 10.1097/01.CCM.0000050454.01978.3B

JL Vincent, 1996, The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine, Intensive Care Med, 22, 707, 10.1007/BF01709751

FL Ferreira, 2001, Serial evaluation of the SOFA score to predict outcome in critically ill patients, JAMA., 286, 1754, 10.1001/jama.286.14.1754

JA Lopes, 2008, Acute kidney injury in intensive care unit patients: a comparison between the RIFLE and the Acute Kidney Injury Network classifications, Crit Care, 12, R110, 10.1186/cc6997

VM Ranieri, 2012, (ARDS Definition Task Force). Acute respiratory distress syndrome: the Berlin Definition, JAMA, 307, 2526

WJ Hubbard, 2005, Cecal ligation and puncture, Shock, 24, 52, 10.1097/01.shk.0000191414.94461.7e

JC Alves-Filho, 2009, Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis, Proc Natl Acad Sci USA, 106, 4018, 10.1073/pnas.0900196106

S Margraf, 2008, Neutrophil-derived circulating free DNA (cf-DNA/NET): a potential prognostic marker for posttraumatic development of inflammatory second hit and sepsis, Shock, 30, 352, 10.1097/SHK.0b013e31816a6bb1

P Lassalle, 1996, ESM-1 is a novel human endothelial cell-specific molecule expressed in lung and regulated by cytokines, J Biol Chem., 271, 20458, 10.1074/jbc.271.34.20458

FQ Cunha, 1994, Differential induction of nitric oxide synthase in various organs of the mouse during endotoxaemia: role of TNF-alpha and IL-1-beta, Immunology, 81, 211

W Meng, 2012, Depletion of neutrophil extracellular traps in vivo results in hypersusceptibility of polymicrobial sepsis in mice, Crit Care, 16, R137, 10.1186/cc11442

L Luo, 2014, Proinflammatory role of neutrophil extracellular traps in abdominal sepsis, Am J Physiol Lung Cell Mol Physiol, 307, L586, 10.1152/ajplung.00365.2013

X Gao, 2015, Neutrophil extracellular traps contribute to the intestine damage in endotoxemic rats, J Surg Res, 195, 211, 10.1016/j.jss.2014.12.019

AK Gupta, 2010, Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death, FEBS Lett., 584, 3193, 10.1016/j.febslet.2010.06.006

S Hamaguchi, 2015, Origin of circulating free DNA in sepsis: analysis of the CLP mouse model, Mediators Inflamm, 2015, 614518, 10.1155/2015/614518

M Saffarzadeh, 2012, Neutrophil Extracellular Traps Directly Induce Epithelial and Endothelial Cell Death: A Predominant Role of Histones, PLoS One, 7, e32366, 10.1371/journal.pone.0032366

SR Clark, 2007, Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood, Nat Med., 13, 463, 10.1038/nm1565

J Xu, 2009, Extracellular histones are major mediators of death in sepsis, Nat Med., 15, 1318, 10.1038/nm.2053

KA Scheibner, 2006, Hyaluronan fragments act as an endogenous danger signal by engaging TLR2, J Immunol, 177, 1272, 10.4049/jimmunol.177.2.1272

R Allam, 2012, Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4, J Am Soc Nephrol., 23, 1375, 10.1681/ASN.2011111077