CNS Inflammation and Bone Marrow Neuropathy in Type 1 Diabetes

The American Journal of Pathology - Tập 183 - Trang 1608-1620 - 2013
Ping Hu1, Jeffrey S. Thinschmidt2, Yuanqing Yan2, Sugata Hazra2, Ashay Bhatwadekar2, Sergio Caballero2, Tatiana Salazar2, Jaleel A. Miyan3, Wencheng Li4, Andrei Derbenev4, Andrea Zsombok4, Maria Tikhonenko5, James M. Dominguez2, Susan P. McGorray6, Daniel R. Saban7, Michael E. Boulton8, Julia V. Busik5, Mohan K. Raizada9, Tailoi Chan-Ling1, Maria B. Grant2
1Department of Anatomy, Bosch Institute, University of Sydney, Sydney, Australia
2Department of Pharmacology and Therapeutics, University of Florida, Gainesville, Florida
3Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom
4Department of Physiology, Tulane University, New Orleans, Louisiana
5Department of Physiology, Michigan State University, East Lansing, Michigan
6Department of Biostatistics, University of Florida, Gainesville, Florida
7Department of Ophthalmology, Duke University, Durham, North Carolina
8Department of Anatomy and Cell Biology, University of Florida, Gainesville, Florida
9Department of Physiology and Functional Genomics, University of Florida, Gainesville, Florida

Tài liệu tham khảo

Reijmer, 2010, Cognitive dysfunction in patients with type 2 diabetes, Diabetes Metab Res Rev, 26, 507, 10.1002/dmrr.1112 Yates, 2012, Impact of metabolic syndrome on cognition and brain: a selected review of the literature, Arterioscler Thromb Vasc Biol, 32, 2060, 10.1161/ATVBAHA.112.252759 Miyan, 1998, Neural regulation of bone marrow, Blood, 92, 2971, 10.1182/blood.V92.8.2971b Massberg, 2007, Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues, Cell, 131, 994, 10.1016/j.cell.2007.09.047 Abboud, 2012, Autonomic neural regulation of the immune system: implications for hypertension and cardiovascular disease, Hypertension, 59, 755, 10.1161/HYPERTENSIONAHA.111.186833 Mignini, 2003, Autonomic innervation of immune organs and neuroimmune modulation, Auton Autacoid Pharmacol, 23, 1, 10.1046/j.1474-8673.2003.00280.x Ganta, 2005, Central angiotensin II-enhanced splenic cytokine gene expression is mediated by the sympathetic nervous system, Am J Physiol Heart Circ Physiol, 289, H1683, 10.1152/ajpheart.00125.2005 Yi, 2012, High-fat-diet exposure induces IgG accumulation in hypothalamic microglia, Dis Model Mech, 5, 686, 10.1242/dmm.009464 Rosas-Ballina, 2011, Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit, Science, 334, 98, 10.1126/science.1209985 Mendez-Ferrer, 2008, Haematopoietic stem cell release is regulated by circadian oscillations, Nature, 452, 442, 10.1038/nature06685 Busik, 2009, Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock, J Exp Med, 206, 2897, 10.1084/jem.20090889 Yamazaki, 1990, Ultrastructural morphometric study of efferent nerve terminals on murine bone marrow stromal cells, and the recognition of a novel anatomical unit: the “neuro-reticular complex.”, Am J Anat, 187, 261, 10.1002/aja.1001870306 Linton, 2004, Age-related changes in lymphocyte development and function, Nat Immunol, 5, 133, 10.1038/ni1033 Joussen, 2004, A central role for inflammation in the pathogenesis of diabetic retinopathy, FASEB J, 18, 1450, 10.1096/fj.03-1476fje Zheng, 2007, Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy, Diabetes, 56, 337, 10.2337/db06-0789 Felten, 1987, Noradrenergic sympathetic neural interactions with the immune system: structure and function, Immunol Rev, 100, 225, 10.1111/j.1600-065X.1987.tb00534.x Geissmann, 2003, Retinoids regulate survival and antigen presentation by immature dendritic cells, J Exp Med, 198, 623, 10.1084/jem.20030390 Hinojosa, 2011, CCL2/MCP-1 modulation of microglial activation and proliferation, J Neuroinflammation, 8, 77, 10.1186/1742-2094-8-77 Schilling, 2009, The role of CC chemokine receptor 2 on microglia activation and blood-borne cell recruitment after transient focal cerebral ischemia in mice, Brain Res, 1289, 79, 10.1016/j.brainres.2009.06.054 Huang, 2005, Chronic expression of monocyte chemoattractant protein-1 in the central nervous system causes delayed encephalopathy and impaired microglial function in mice, FASEB J, 19, 761, 10.1096/fj.04-3104com Semple, 2010, Role of CCL2 (MCP-1) in traumatic brain injury (TBI): evidence from severe TBI patients and CCL2-/- mice, J Cereb Blood Flow Metab, 30, 769, 10.1038/jcbfm.2009.262 Tsou, 2007, Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites, J Clin Invest, 117, 902, 10.1172/JCI29919 Brucklacher, 2008, Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response, BMC Med Genomics, 1, 26, 10.1186/1755-8794-1-26 Feit-Leichman, 2005, Vascular damage in a mouse model of diabetic retinopathy: relation to neuronal and glial changes, Invest Ophthalmol Vis Sci, 46, 4281, 10.1167/iovs.04-1361 Caballero, 2007, Ischemic vascular damage can be repaired by healthy, but not diabetic, endothelial progenitor cells, Diabetes, 56, 960, 10.2337/db06-1254 Chan-Ling, 1997, Glial, vascular, and neuronal cytogenesis in whole-mounted cat retina, Microsc Res Tech, 36, 1, 10.1002/(SICI)1097-0029(19970101)36:1<1::AID-JEMT1>3.0.CO;2-V Nakano, 2001, Differentiation of transplanted bone marrow cells in the adult mouse brain, Transplantation, 71, 1735, 10.1097/00007890-200106270-00006 Ito, 1998, Microglia-specific localisation of a novel calcium binding protein, Iba1, Brain Res Mol Brain Res, 57, 1, 10.1016/S0169-328X(98)00040-0 Vincent, 2007, Inhibition of caspase-1/interleukin-1beta signaling prevents degeneration of retinal capillaries in diabetes and galactosemia, Diabetes, 56, 224, 10.2337/db06-0427 Zheng, 2002, Neuronal expression of fos protein in the forebrain of diabetic rats, Brain research, 956, 268, 10.1016/S0006-8993(02)03550-3 Morgan, 1987, Mapping patterns of c-fos expression in the central nervous system after seizure, Science, 237, 192, 10.1126/science.3037702 Hazra, 2013, Long-term type 1 diabetes influences haematopoietic stem cells by reducing vascular repair potential and increasing inflammatory monocyte generation in a murine model, Diabetologia, 56, 644, 10.1007/s00125-012-2781-0 Haus, 1999, Biologic rhythms in the immune system, Chronobiol Int, 16, 581, 10.3109/07420529908998730 Kamenov, 2012, Diabetic autonomic neuropathy, Adv Exp Med Biol, 771, 176, 10.1007/978-1-4614-5441-0_15 Harrison, 2006, Diabetic hepatosclerosis: diabetic microangiopathy of the liver, Arch Pathol Lab Med, 130, 27, 10.5858/2006-130-27-DHDMOT Kazakos, 2008, The impact of diabetic autonomic neuropathy on the incretin effect, Med Sci Monit, 14, CR213 Cano, 2004, Dual viral transneuronal tracing of central autonomic circuits involved in the innervation of the two kidneys in rat, J Comp Neurol, 471, 462, 10.1002/cne.20040 Cano, 2001, Characterization of the central nervous system innervation of the rat spleen using viral transneuronal tracing, J Comp Neurol, 439, 1, 10.1002/cne.1331 Peterson, 2006, Reactive oxygen species in the neuropathogenesis of hypertension, Curr Hypertens Rep, 8, 232, 10.1007/s11906-006-0056-1 Chen, 2010, Hematopoietic origin of pathological grooming in Hoxb8 mutant mice, Cell, 141, 775, 10.1016/j.cell.2010.03.055 Longo, 2010, Distribution and proliferation of bone marrow cells in the brain after pilocarpine-induced status epilepticus in mice, Epilepsia, 51, 1628, 10.1111/j.1528-1167.2010.02570.x Amann, 2003, ACE inhibitors improve diabetic nephropathy through suppression of renal MCP-1, Diabetes Care, 26, 2421, 10.2337/diacare.26.8.2421 Wakabayashi, 2011, Increases of vitreous monocyte chemotactic protein 1 and interleukin 8 levels in patients with concurrent hypertension and diabetic retinopathy, Retina, 31, 1951, 10.1097/IAE.0b013e31820d3cee Sell, 2006, Monocyte chemotactic protein-1 is a potential player in the negative cross-talk between adipose tissue and skeletal muscle, Endocrinology, 147, 2458, 10.1210/en.2005-0969 Meleth, 2005, Serum inflammatory markers in diabetic retinopathy, Invest Ophthalmol Vis Sci, 46, 4295, 10.1167/iovs.04-1057 Piemonti, 2009, Association between plasma monocyte chemoattractant protein-1 concentration and cardiovascular disease mortality in middle-aged diabetic and nondiabetic individuals, Diabetes Care, 32, 2105, 10.2337/dc09-0763 Simeoni, 2004, Association between the A-2518G polymorphism in the monocyte chemoattractant protein-1 gene and insulin resistance and type 2 diabetes mellitus, Diabetologia, 47, 1574, 10.1007/s00125-004-1494-4 Katakami, 2010, Monocyte chemoattractant protein-1 (MCP-1) gene polymorphism as a potential risk factor for diabetic retinopathy in Japanese patients with type 2 diabetes, Diabetes Res Clin Pract, 89, e9, 10.1016/j.diabres.2010.04.006 Moon, 2007, Association of polymorphisms in monocyte chemoattractant protein-1 promoter with diabetic kidney failure in Korean patients with type 2 diabetes mellitus, J Korean Med Sci, 22, 810, 10.3346/jkms.2007.22.5.810 Shanmugam, 2003, High glucose-induced expression of proinflammatory cytokine and chemokine genes in monocytic cells, Diabetes, 52, 1256, 10.2337/diabetes.52.5.1256 Takaishi, 2003, High glucose accelerates MCP-1 production via p38 MAPK in vascular endothelial cells, Biochem Biophys Res Commun, 305, 122, 10.1016/S0006-291X(03)00712-5 Luo, 2002, Neuronal and glial response in the rat hypothalamus-neurohypophysis complex with streptozotocin-induced diabetes, Brain Res, 925, 42, 10.1016/S0006-8993(01)03258-9 Klein, 2004, Apoptosis of vasopressinergic hypothalamic neurons in chronic diabetes mellitus, Neurobiol Dis, 15, 221, 10.1016/j.nbd.2003.10.009 Dheen, 1994, Ultrastructural changes in the hypothalamic supraoptic nucleus of the streptozotocin-induced diabetic rat, J Anatomy, 184, 615 Dheen, 1994, Ultrastructural changes in the hypothalamic paraventricular nucleus of the streptozotocin-induced diabetic rat, Acta Anat, 149, 291, 10.1159/000147590 Fernstrom, 1990, In vivo somatostatin, vasopressin, and oxytocin synthesis in diabetic rat hypothalamus, Am J Physiol, 258, E661 Amin, 1996, A novel mechanism of action of tetracyclines: effects on nitric oxide synthases, Proc Natl Acad Sci U S A, 93, 14014, 10.1073/pnas.93.24.14014 Sanchez Mejia, 2001, Friedlander RM: Caspases in Huntington’s disease, Neuroscientist, 7, 480, 10.1177/107385840100700604 Zhu, 2002, Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice, Nature, 417, 74, 10.1038/417074a Barza, 1975, Relation between lipophilicity and pharmacological behavior of minocycline, doxycycline, tetracycline, and oxytetracycline in dogs, Antimicrob Agents Chemother, 8, 713, 10.1128/AAC.8.6.713 Yellowlees Douglas, 2012, Grant MB: Bone marrow-CNS connections: implications in the pathogenesis of diabetic retinopathy, Prog Retin Eye Res, 31, 481, 10.1016/j.preteyeres.2012.04.005 Dray, 2008, Neuropathic pain: emerging treatments, Br J Anaesth, 101, 48, 10.1093/bja/aen107 Cukras, 2012, Oral minocycline for the treatment of diabetic macular edema (DME): results of a phase I/II clinical study, Invest Ophthalmol Vis Sci, 53, 3865, 10.1167/iovs.11-9413