Elicitor signal transduction leading to production of plant secondary metabolites

Biotechnology Advances - Tập 23 - Trang 283-333 - 2005
Jian Zhao1, Lawrence C. Davis2, Robert Verpoorte3
1Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
2Department of Biochemistry Kansas State University, Manhattan, KS 66506 USA
3Division of Pharmacognosy, Section Metabolomics, Institute of Biology, Leiden University, NL-2300 RA, Leiden, The Netherlands

Tài liệu tham khảo

Aharon, 1998, Activation of a plant plasma membrane Ca2+ channel by TGα1, a heterotrimeric G protein alpha-subunit homologue, FEBS Lett, 424, 17, 10.1016/S0014-5793(98)00129-X Allen, 1995, Release of Ca2+ from individual plant vacuoles by both InsP3 and cyclic-ADP-ribose, Science, 268, 735, 10.1126/science.7732384 Allwood, 1999, Phosphorylation of phenylalanine ammonia-lyase: evidence for a novel protein kinase and identification of the phosphorylated residue, FEBS Lett, 457, 47, 10.1016/S0014-5793(99)00998-9 Apone, 2003, The G-protein-coupled receptor GCR1 regulates DNA synthesis through activation of phosphatidylinositol-specific phospholipase C, Plant Physiol, 133, 571, 10.1104/pp.103.026005 Armero, 2001, Possible role of plasma membrane H+-ATPase in the elicitation of phytoalexin and related isoflavone root secretion in chickpea (Cicer arietinum L.) seedlings, Plant Sci, 161, 791, 10.1016/S0168-9452(01)00472-1 Armero, 2001, Release of phytoalexins and related isoflavonoids from intact chickpea seedlings elicited with reduced glutathione at root level, Plant Physiol Biochem, 39, 785, 10.1016/S0981-9428(01)01299-2 Assmann, 2002, Heterotrimeric and unconventional GTP binding proteins in plant cell signaling, Plant Cell, 14, S355, 10.1105/tpc.001792 Avancini, 2003, Induction of pilocarpine formation in jaborandi leaves by salicylic acid and methyljasmonate, Phytochemistry, 63, 171, 10.1016/S0031-9422(03)00102-X Aziz, 2003, Laminarin elicits defense responses in grapevine and induces protection against Botrytis cinerea and Plasmopara viticola, Mol Plant-Microb Interact, 16, 1118, 10.1094/MPMI.2003.16.12.1118 Bate, 1998, Molecular characterization of an Arabidopsis gene encoding hydroperoxide lyase, a cytochrome P-450 that is wound inducible, Plant Physiol, 117, 1393, 10.1104/pp.117.4.1393 Bauer, 2001, Sensitivity of different ecotypes and mutants of Arabidopsis thaliana toward the bacterial elicitor flagellin correlates with the presence of receptor-binding sites, J Biol Chem, 276, 45669, 10.1074/jbc.M102390200 Bennett, 1994, Secondary metabolites in plant defense mechanisms, New Phytol, 127, 617, 10.1111/j.1469-8137.1994.tb02968.x Berridge, 1993, Inositol trisphosphate and calcium signaling, Nature, 361, 315, 10.1038/361315a0 Blechert, 1995, The octadecanoid pathway: signal molecules for the regulation of secondary pathways, Proc Natl Acad Sci U S A, 92, 4099, 10.1073/pnas.92.10.4099 Blée, 1998, Phytooxylipins and plant defense reactions, Prog Lipid Res, 37, 33, 10.1016/S0163-7827(98)00004-6 Blume, 2000, Receptor-mediated increase in cytoplasmic free calcium required for activation of pathogen defense in parsley, Plant Cell, 12, 1425, 10.1105/tpc.12.8.1425 Boller, 1995, Chemoperception of microbial signals in plant cells, Annu Rev Plant Physiol Plant Mol Biol, 46, 189, 10.1146/annurev.pp.46.060195.001201 Bolwell, 1995, The reluctant messenger in plants, Trends Biochem Sci, 12, 492, 10.1016/S0968-0004(00)89114-8 Bolwell, 1997, Mechanism for the generation of reactive oxygen species in plant defence—a broad perspective, Physiol Mol Plant Pathol, 51, 347, 10.1006/pmpp.1997.0129 Booker, 2004, Differential responses of G-protein Arabidopsis thaliana mutants to ozone, New Phytol, 162, 633, 10.1111/j.1469-8137.2004.01081.x Bourque, 1999, Characterization of the cryptogein binding sites on plant plasma membranes, J Biol Chem, 274, 34699, 10.1074/jbc.274.49.34699 Bowler, 1994, Cyclic GMP and calcium mediate phytochrome phototransduction, Cell, 77, 73, 10.1016/0092-8674(94)90236-4 Brader, 2001, Jasmonate-dependent induction of indole glucosinolates in Arabidopsis by culture filtrates of the nonspecific pathogen Erwinia carotovora, Plant Physiol, 126, 849, 10.1104/pp.126.2.849 Bradley, 1998, The maize Lc regulatory gene up regulates the flavonoid biosynthetic pathway of Petunia, Plant J, 13, 381, 10.1046/j.1365-313X.1998.00031.x Brandle, 2002, Leaf ESTs from Stevia rebaudiana: a resource for gene discovery in diterpene synthesis, Plant Mol Biol, 50, 613, 10.1023/A:1019993221986 Brown, 2003, A role for the GCC-box in jasmonate-mediated activation of the PDF1.2 gene of Arabidopsis, Plant Physiol, 132, 1020, 10.1104/pp.102.017814 Bulgakov, 2002, Effect of salicylic acid, methyl jasmonate, ethephon and cantharidin on anthraquinone production by Rubia cordifolia callus cultures transformed with the rolB and rolC genes, J Biotechnol, 97, 213, 10.1016/S0168-1656(02)00067-6 Burbulis, 1999, Interactions among enzymes of the Arabidopsis flavonoid biosynthetic pathway, Proc Natl Acad Sci U S A, 96, 12929, 10.1073/pnas.96.22.12929 Cessna, 2001, Measurement of stress-induced Ca2+ pulses in single aequorin-transformed tobacco cells, Cell Calcium, 30, 151, 10.1054/ceca.2001.0226 Chandok, 1998, ZmcPKC70, a protein kinase C-type enzyme from maize, J Biol Chem, 273, 19235, 10.1074/jbc.273.30.19235 Chandra, 1997, Measurement of Ca2+ fluxes during elicitation of the oxidative burst in aequorin-transformed tobacco cells, J Biol Chem, 272, 28274, 10.1074/jbc.272.45.28274 Chappell, 1995, Biosynthesis and molecular biology of the isoprenoid biosynthetic pathway in plants, Annu Rev Plant Physiol Plant Mol Biol, 46, 521, 10.1146/annurev.pp.46.060195.002513 Chen, 2000, Effect of yeast elicitor on the secondary metabolism of Ti-transformed Salvia miltiorrhiza cell suspension cultures, Plant Cell Rep, 19, 710, 10.1007/s002999900166 Cheng, 2001, Molecular identification of phenylalanine ammonia-lyase as a substrate of a specific constitutively active Arabidopsis CDPK expressed in maize protoplasts, FEBS Lett, 503, 185, 10.1016/S0014-5793(01)02732-6 Chiron, 2000, Gene induction of stilbene biosynthesis in Scots pine in response to ozone treatment, wounding, and fungal infection, Plant Physiol, 124, 865, 10.1104/pp.124.2.865 Choi, 1994, Proc Natl Acad Sci U S A, 91, 2329, 10.1073/pnas.91.6.2329 Chung, 2001, Tissue specific and inducible expression of resveratrol synthase gene in peanut plants, Mol Cell, 12, 353 Clive Lo, 1998, Reduction of light-induced anthocyanin accumulation in inoculated Sorghum mesocotyls, implications for a compensatory role in the defense response, Plant Physiol, 116, 979, 10.1104/pp.116.3.979 Clough, 2000, The Arabidopsis dnd1 “defense, no death” gene encodes a mutated cyclic nucleotide-gated ion channel, Proc Natl Acad Sci U S A, 97, 9323, 10.1073/pnas.150005697 Creelman, 1997, Biosynthesis and action of jasmonates in plants, Annu Rev Plant Physiol Plant Mol Biol, 48, 355, 10.1146/annurev.arplant.48.1.355 Croft, 1993, Volatile products of the lipoxygenase pathway evolved from Phaseolus vulgaris (L.) leaves inoculated with Pseudomonas syringae pv phaseolicola, Plant Physiol, 101, 13, 10.1104/pp.101.1.13 Dangl, 2001, Plant pathogen and integrated defense responses to infection, Nature, 411, 826, 10.1038/35081161 Davies, 2003, Transcriptional regulation of secondary metabolism, Funct Plant Biol, 30, 913, 10.1071/FP03062 Day, 2000, Differential expression of two soybean apyrases, one of which is an early nodulin, Mol Plant-Microb Interact, 13, 1053, 10.1094/MPMI.2000.13.10.1053 Degousee, 1994, Involvement of oxidative processes in the signaling mechanisms leading to the activation of glyceollin synthesis in soybean (Glycine max), Plant Physiol, 104, 945, 10.1104/pp.104.3.945 de Jong, 2004, Phosphatidic acid accumulation is an early response in the Cf-4/Avr4 interaction, Plant J, 39, 1, 10.1111/j.1365-313X.2004.02110.x Delledonne, 1998, Nitric oxide functions as a signal in plant disease resistance, Nature, 394, 585, 10.1038/29087 Denekamp, 2003, Integration of wounding and osmotic stress signals determines the expression of the AtMYB102 transcription factor gene, Plant Physiol, 132, 1415, 10.1104/pp.102.019273 Dietrich, 1990, Fungal elicitor triggers rapid, transient, and specific protein phosphorylation in parsley cell suspension cultures, J Biol Chem, 265, 6360, 10.1016/S0021-9258(19)39334-2 Dittrich, 1992, The jasmonate precursor, 12-oxo-phytodienoic acid, induces phytoalexin synthesis in Petroselinum crispum cell cultures, FEBS Lett, 309, 33, 10.1016/0014-5793(92)80733-W Dixon, 2000, Genetic complaxity of pathogen perception by plants: the example of Rcr3, a tomato gene required specifically by Cf-2, Proc Natl Acad Sci U S A, 97, 8807, 10.1073/pnas.97.16.8807 Dolmetsch, 1997, Differential activation of transcription factors induced by Ca2+ response amplitude and duration, Nature, 386, 855, 10.1038/386855a0 Durner, 1998, Defense gene induction in tobacco by nitric oxide, cyclic GMP, and cyclic ADP-ribose, Proc Natl Acad Sci U S A, 95, 10328, 10.1073/pnas.95.17.10328 Ebel, 1998, Early events in the elicitation of plant defense, Planta, 206, 335, 10.1007/s004250050409 Edwards, 1991, Glutathione and elicitation of the phytoalexin response in legume cell cultures, Planta 1998, 184, 403 El-Kereamy, 2003, Exogenous ethylene stimulates the long-term expression of genes related to anthocyanin biosynthesis in grape berries, Physiol Plant, 119, 175, 10.1034/j.1399-3054.2003.00165.x Etzler, 1999, A Nod-factor binding lectin with apyrase activity, Proc Natl Acad Sci U S A, 96, 5856, 10.1073/pnas.96.10.5856 Eulgem, 1999, Early nuclear events in plant defense: rapid gene activation by WRKY transcription factors, EMBO J, 18, 4689, 10.1093/emboj/18.17.4689 Eulgem, 2000, The WRKY superfamily of plant transcription factors, Trends Plant Sci, 5, 199, 10.1016/S1360-1385(00)01600-9 Fan, 2000, Biosynthesis of phytoalexin in carrot root requires ethylene action, Physiol Plant, 110, 450, 10.1111/j.1399-3054.2000.1100404.x Farmer, 2003, Jasmonates and related oxylipins in plant responses to pathogenesis and herbivory, Curr Opin Plant Biol, 6, 372, 10.1016/S1369-5266(03)00045-1 Felix, 1991, Rapid changes of protein phosphorylation are involved in transduction of the elicitor signal in plant cells, Proc Natl Acad Sci U S A, 88, 8831, 10.1073/pnas.88.19.8831 Fliegmann, 2003, The role of octadecanoids and functional mimics in soybean defense responses, Biol Chem, 384, 437, 10.1515/BC.2003.049 Fliegmann, 2004, An ancient enzyme domain hidden in the putative β-glucan elicitor receptor of soybean may play an active part in the perception of pathogen-associated molecular patterns during broad host resistance, J Biol Chem, 279, 1132, 10.1074/jbc.M308552200 Foissner, 2000, In vivo imaging of an elicitor-induced nitric oxide burst in tobacco, Plant J, 23, 817, 10.1046/j.1365-313X.2000.00835.x Fujimoto, 2000, Arabidopsis ethylene-responsive element binding factors act as transcriptional activators or repressors of GCC box-mediated gene expression, Plant Cell, 12, 393, 10.1105/tpc.12.3.393 Galán, 1999, Type III secretion machines: bacterial devices for protein delivery into host cells, Science, 284, 1322, 10.1126/science.284.5418.1322 Gantet, 1998, Necessity of a functional octadecanoic pathway for indole alkaloid synthesis by Catharanthus roseus cell suspension-cultured in an auxin-starved medium, Plant Cell Physiol, 39, 220, 10.1093/oxfordjournals.pcp.a029360 Gelli, 1997, Activation of plant plasma membrane Ca2+-permeable channels by race-specific fungal elicitors, Plant Physiol, 113, 269, 10.1104/pp.113.1.269 Goossens, 2003, A functional genomics approach toward the understanding of secondary metabolism in plant cells, Proc Natl Acad Sci U S A, 100, 8595, 10.1073/pnas.1032967100 Graham, 1996, Signaling in soybean phenylpropanoid responses: dissection of primary, secondary, and conditioning effects of light, wounding, and elicitor treatments, Plant Physiol, 110, 1123, 10.1104/pp.110.4.1123 Grotewold, 1998, Engineering secondary metabolism in maize cells by ectopic expression of transcription factors, Plant Cell, 10, 721, 10.1105/tpc.10.5.721 Gundlach, 1992, Jasmonic acid is a signal transducer in elicitor-induced plant cell cultures, Proc Natl Acad Sci U S A, 89, 2389, 10.1073/pnas.89.6.2389 Guo, 1998, Potentiation of the oxidative burst and isoflavonoid phytoalexin accumulation by serine protease inhibitors, Plant Physiol, 118, 1487, 10.1104/pp.118.4.1487 Hahlbrock, 2003, Non-self recognition, transcriptional reprogramming, and secondary metabolite accumulation during plant/pathogen interactions, Proc Natl Acad Sci U S A, 100, 14569, 10.1073/pnas.0831246100 Hammerschmidt, 1999, Phytoalexins: what have we learned after 60 years?, Annu Rev Phytopathol, 37, 285, 10.1146/annurev.phyto.37.1.285 Hayashi, 2003, Up-regulation of soyasaponin biosynthesis by methyl jasmonate in cultured cells of Glycyrrhiza glabra, Plant Cell Physiol, 44, 404, 10.1093/pcp/pcg054 He, 1998, Gene activation by cytoplasmic acidification in suspension-cultured rice cells in response to the potent elicitor, N-acetylchitoheptaose, Mol Plant-Microb Interact, 11, 1167, 10.1094/MPMI.1998.11.12.1167 Hefner, 1998, Cloning and functional expression of a cDNA encoding geranylgeranyl diphosphate synthase from Taxus canadensis and assessment of the role of this prenyltransferase in cells induced for taxol production, Arch Biochem Biophys, 360, 62, 10.1006/abbi.1998.0926 Hu, 2003, Hydrogen peroxide and jasmonic acid mediate oligogalacturonic acid-induced saponin synthesis in suspension-cultured cells of Panax ginseng, Physiol Plant, 118, 414, 10.1034/j.1399-3054.2003.00124.x Hu, 2003, Nitric oxide mediates elicitor-induced saponin synthesis in cell cultures of Panax ginseng, Funct Plant Biol, 30, 901, 10.1071/FP03061 Ito, 1997, Identification of a high-affinity binding protein for N-acetylchitooligosaccharide elicitor in the plasma membrane of suspension-cultured rice cells by affinity labeling, Plant J, 12, 347, 10.1046/j.1365-313X.1997.12020347.x Jabs, 1997, Elicitor-stimulated ion fluxes and O2− from the oxidative burst are essential components in triggering defense gene activation and phytoalexin synthesis in parsley, Proc Natl Acad Sci U S A, 94, 4800, 10.1073/pnas.94.9.4800 Ji, 1998, Characterization of a 34-kDa soybean binding protein for the syringolide elicitors, Proc Natl Acad Sci U S A, 95, 3306, 10.1073/pnas.95.6.3306 Kahl, 2000, Herbivore-induced ethylene suppresses a direct defense but not a putative indirect defense against an adapted herbivore, Planta, 210, 336, 10.1007/PL00008142 Kandlbinder, 2004, The antioxidant status of photosynthesizing leaves under nutrient deficiency: redox regulation, gene expression and antioxidant activity in Arabidopsis thaliana, Physiol Plant, 120, 63, 10.1111/j.0031-9317.2004.0272.x Kang, 2004, Effects of methyl jasmonate and salicylic acid on the production of tropane alkaloids and the expression of PMT and H6H in adventitious root cultures of Scopolia parviflora, Plant Sci, 166, 745, 10.1016/j.plantsci.2003.11.022 Kasparovsky, 2003, Elicitation of tobacco cells with ergosterol activates a signal pathway including mobilization of internal calcium, Plant Physiol Biochem, 41, 495, 10.1016/S0981-9428(03)00058-5 Kawasaki, 1999, The small GTP-binding protein Rac is a regulator of cell death in plants, Proc Natl Acad Sci U S A, 96, 10922, 10.1073/pnas.96.19.10922 Keller, 1998, A plant homolog of the neutrophil NADPH oxidase gp91phox subunit gene encodes a plasma membrane protein with Ca2+ binding motifs, Plant Cell, 10, 255, 10.1105/tpc.10.2.255 Ketchum, 2003, Taxus metabolomics: methyl jasmonate preferentially induces production of taxoids oxygenated at C-13 in Taxus x media cell cultures, Phytochem, 62, 901, 10.1016/S0031-9422(02)00711-2 Kiddle, 1994, Salicylic acid induced accumulation of glucosinolates in oilseed rape leaves, J Exp Bot, 45, 1343, 10.1093/jxb/45.9.1343 Kim, 2003, A rice isoflavone reductase-like gene, OsIRL, is induced by rice blast fungal elicitor, Mol Cell, 16, 224 Kirakosyan, 2000, Stimulation of the production of hypericin by mannan in Hypericum perforatum shoot cultures, Phytochemistry, 53, 345, 10.1016/S0031-9422(99)00496-3 Klessig, 2000, Nitric oxide and salicylic acid signaling in plant defenses, Proc Natl Acad Sci U S A, 97, 8849, 10.1073/pnas.97.16.8849 Koga, 1998, Cerebrosides A and C, sphingolipid elicitors of hypersensitive cell death and phytoalexin accumulation in rice plants, J Biol Chem, 273, 31985, 10.1074/jbc.273.48.31985 Kravchuk, 2003, Role of active forms of oxygen in the induction of phytoalexin synthesis in Allium cepa cells, Tsitol Genet, 37, 30 Kuchitsu, 1995, EPR evidence for generation of hydroxyl radical triggered by N-acetylchitooligosaccharide elicitor and a protein phosphatase inhibitor in suspension-cultured rice cells, Protoplasma, 188, 139, 10.1007/BF01276805 Kurosaki, 1997, Role of inward K+ channel located at carrot plasma membrane in signal cross-talking of cAMP with Ca2+ cascade, FEBS Lett, 408, 115, 10.1016/S0014-5793(97)00403-1 Kurosaki, 1987, Breakdown of phosphatidylinositol during the elicitation of phytoalexin production in cultured carrot cells, Plant Physiol, 85, 601, 10.1104/pp.85.3.601 Kurosaki, 2001, Involvement of GTP-binding protein in the induction of phytoalexin biosynthesis in cultured carrot cells, Plant Sci, 161, 273, 10.1016/S0168-9452(01)00407-1 Kwak, 1997, The requirements for Ca2+, protein phosphorylation, and dephosphorylation for ethylene signal transduction in Pisum sativm L, Plant Cell Physiol, 38, 1142, 10.1093/oxfordjournals.pcp.a029099 Lait, 2003, Rapid biosynthesis of N-linolenoyl-l-glutamine, an elicitor of plant volatiles, by membrane-associated enzyme(s) in Manduca sexta, Proc Natl Acad Sci U S A, 100, 7027, 10.1073/pnas.1232474100 Lamotte, 2004, Analysis of nitric oxide signaling functions in tobacco cells challenged by the elicitor cryptogein, Plant Physiol, 135, 516, 10.1104/pp.104.038968 Lange, 2000, Probing essential oil biosynthesis and secetion by functional evaluation of expressed sequence tags from mint glandular trichomes, Proc Natl Acad Sci U S A, 97, 2934, 10.1073/pnas.97.6.2934 Lapous, 1998, Increase of defense gene transcripts by cytoplasmic acidification in tobacco cell suspension cultures, Planta, 205, 452, 10.1007/s004250050343 Lebrun-Garcia, 1998, Activation of MAPK homologues by elicitors in tobacco cells, Plant J, 15, 773, 10.1046/j.1365-313X.1998.00269.x Lecourieux, 2000, Phosphoproteins involved in the signal transduction of cryptogein, an elicitor of defense reactions in tobacco, Mol Plant-Microb Interact, 13, 821, 10.1094/MPMI.2000.13.8.821 Lecourieux, 2002, Analysis and effects of cytosolic free calcium increases in response to elicitors in Nicotiana plumbaginifolia cells, Plant Cell, 14, 2627, 10.1105/tpc.005579 Lee, 2001, A harpin binding site in tobacco plasma membranes mediates activation of the pathogenesis-related gene HIN1 independent of extracellular calcium but dependent on mitogen-activated protein kinase activity, Plant Cell, 13, 1079, 10.1105/tpc.13.5.1079 Legendre, 1992, Evidence for participation of GTP-binding proteins in elicitation of the rapid oxidative burst in cultured soybean cells, J Biol Chem, 267, 20140, 10.1016/S0021-9258(19)88677-5 Lein, 2001, Cloning and direct G-protein regulation of phospholipase D from tobacco, Biochim Biophys Acta, 1530, 172, 10.1016/S1388-1981(00)00182-7 Levine, 1994, H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response, Cell, 79, 583, 10.1016/0092-8674(94)90544-4 Li, 1994, Cyclic AMP stimulates K+ channel activity in mesophyll cells of Vicia faba L, Plant Physiol, 106, 957, 10.1104/pp.106.3.957 Li, 2004, The WRKY70 transcription factor: a node of convergence for jasmonate-mediated and salicylate-mediated signals in plant defense, Plant Cell, 16, 319, 10.1105/tpc.016980 Ligterink, 1997, Receptor-mediated activation of a MAP kinase in pathogen defense of plants, Science, 276, 2054, 10.1126/science.276.5321.2054 Linden, 2000, Oligosaccharides potentiate methyl jasmonate-induced production of paclitaxel in Taxus canadensis, Plant Sci, 158, 41, 10.1016/S0168-9452(00)00306-X Liu, 1999, Transcription factors and their genes in higher plants functional domains, evolution and regulation, Eur J Biochem, 262, 247, 10.1046/j.1432-1327.1999.00349.x Lorenzo, 2003, Ethylene response factor1 integrates signals from ethylene and jasmonate pathways in plant defense, Plant Cell, 15, 165, 10.1105/tpc.007468 Loreti, 2002, Elicitors of defence responses repress a gibberellin signalling pathway in barley embryos, J Plant Physiol, 159, 1383, 10.1078/0176-1617-00747 Luo, 2001, Enhancement of paclitaxel production by abscisic acid in cell suspension cultures of Taxus chinensis, Biotechnol Lett, 23, 1345, 10.1023/A:1010597802741 Madsen, 2003, A receptor kinase gene of the LysM type is involved in legume perception of rhizobial signals, Nature, 425, 637, 10.1038/nature02045 Mahady, 1998, Involvement of protein kinase and G proteins in the signal transduction of benzophenanthridine alkaloid biosynthesis, Phytochemistry, 48, 93, 10.1016/S0031-9422(97)00823-6 Maleck, 2000, The transcriptome of Arabidopsis thaliana during systemic acquired resistance, Nat Gen, 26, 403, 10.1038/82521 Mandujano-Chavez, 2000, Differential induction of sesquiterpene metabolism in tobacco cell suspension cultures by methyl jasmonate and fungal elicitor, Arch Biochem Biophys, 381, 285, 10.1006/abbi.2000.1961 Matsuda, 2001, Involvement of reactive oxygen species in the induction of (S)-N-p-coumaroyloctopamine accumulation by β-1,3-glucooligosaccharide elicitors in potato tuber tissues, J Biosci, 56, 228 Mehdy, 1994, Active oxygen species in plant defense against pathogens, Plant Physiol, 105, 467, 10.1104/pp.105.2.467 Meijer, 2003, Phospholipid-based signaling in plants, Annu Rev Plant Biol, 54, 265, 10.1146/annurev.arplant.54.031902.134748 Meindl, 2000, The bacterial elicitor flagellin activates its receptor in tomato cells according to the address-message concept, Plant Cell, 12, 1783, 10.1105/tpc.12.9.1783 Memelink, 2001, Genetic modification of plant secondary metabolite pathways using transcriptional regulators, Adv Biochem Eng Biotechnol, 72, 103 Menke, 1999, Involvement of the octadecanoid pathway and protein phosphorylation in fungal elicitor-induced expression of terpenoid indole alkaloid biosynthetic genes in Catharanthus roseus, Plant Physiol, 119, 1289, 10.1104/pp.119.4.1289 Meyer, 2001, The lipopolysaccharides of the phytopathogen Xanthomonas campestris pv. campestris induce an oxidative burst reaction in cell cultures of Nicotiana tabacum, Planta, 213, 214, 10.1007/s004250000493 Meyers, 2003, Genome-wide analysis of NBS-LRR-encoding genes in Arabidopsis, Plant Cell, 15, 809, 10.1105/tpc.009308 Mikkelsen, 2003, Modulation of CYP79 genes and glucosinolate profiles in Arabidopsis by defense signaling pathways, Plant Physiol, 131, 298, 10.1104/pp.011015 Mirjalili, 1996, Methyl jasmonate induced production of taxol in suspension cultures of Taxus cuspidata: ethylene interaction and induction models, Biotechnol Prog, 12, 110, 10.1021/bp9500831 Mithofer, 2001, Induction of H2O2 synthesis by β-glucan elicitors in soybean is independent of cytosolic calcium transients, FEBS Lett, 508, 191, 10.1016/S0014-5793(01)03054-X Mithofer, 2004, Biotic and heavy metal stress response in plants: evidence for common signals, FEBS Lett, 566, 1, 10.1016/j.febslet.2004.04.011 Mizukami, 1993, Methyl jasmonate-induced rosmarinic acid biosynthesis in Lithospermum erythrorthizon cell suspension cultures, Plant Cell Rep, 12, 706, 10.1007/BF00233424 Modolo, 2002, Nitric oxide synthase-mediated phytoalexin accumulation in soybean cotyledons in response to the Diaporthe phaseolorum f. sp. meridionalis elicitor, Plant Physiol, 130, 1288, 10.1104/pp.005850 Mooney, 1995, Altered regulation of tomato and tobacco pigmentation genes caused by the delila gene of Antirrhinum, Plant J, 7, 333, 10.1046/j.1365-313X.1995.7020333.x Morel, 2004, Rac regulation of NtrbohD, the oxidase responsible for the oxidative burst in elicited tobacco cell, Plant J, 37, 282, 10.1046/j.1365-313X.2003.01957.x Morris, 2001, MAP kinase signal transduction pathways on plants, New Phytol, 151, 67, 10.1046/j.1469-8137.2001.00167.x Mueller, 1993, Signaling in the elicitation process is mediated through the octadecanoid pathway leading to jasmonic acid, Proc Natl Acad Sci USA, 90, 7490, 10.1073/pnas.90.16.7490 Munnik, 2001, Phosphatidic acid: an emerging plant lipid second messenger, Trends Plant Sci, 6, 227, 10.1016/S1360-1385(01)01918-5 Neill, 1994, Differential effects of elicitors on secondary metabolism in hairy root cultures of tobacco (Nicotiana tabacum), Biochem Soc Trans, 22, 383, 10.1042/bst0220383 Neill, 2002, Hydrogen peroxide and nitric oxide as signal molecules in plants, J Exp Bot, 53, 1237, 10.1093/jexbot/53.372.1237 Nennstiel, 1998, Characterization and partial purification of an oligopeptide elicitor receptor from parsley (Petroselinum crispum), FEBS Lett, 431, 405, 10.1016/S0014-5793(98)00800-X Nimchuk, 2003, Recognition and response in the plant immune system, Annu Rev Genet, 37, 579, 10.1146/annurev.genet.37.110801.142628 Nojiri, 1996, Involvement of jasmonic acid in elicitor-induced phytoalexin production in suspension-cultured rice cells, Plant Physiol, 110, 387, 10.1104/pp.110.2.387 Noritake, 1996, Nitric oxide induces phytoalexin accumulation in potato tuber tissue, Plant Cell Physiol, 37, 113, 10.1093/oxfordjournals.pcp.a028908 Ogura, 2001, Induction of hydroxycinnamic acid amides and tryptophan by jasmonic acid, abscisic acid and osmotic stress in barley leaves, Z Naturforsch, 56, 193, 10.1515/znc-2001-3-405 Okada, 2002, High-affinity binding proteins for N-acetylchitooligosaccharide elicitor in the plasma membranes from wheat, barley and carrot cells: conserved presence and correlation with the responsiveness to the elicitor, Plant Cell Physiol, 43, 505, 10.1093/pcp/pcf060 Ortega, 2001, Participation of the phosphoinositide metabolism in the hypersensitive response of Citrus limon against Alternaria alternata, Biol Res, 34, 43, 10.4067/S0716-97602001000100014 Ortega, 2002, Signal transduction in lemon seedlings in the hypersensitive response against Alternaria alternata: participation of calmodulin G-protein and protein kinases, Biol Res, 35, 373, 10.4067/S0716-97602002000300012 Ouaked, 2003, A MAPK pathway mediates ethylene signaling in plants, EMBO J, 22, 1282, 10.1093/emboj/cdg131 Pan, 2000, Scale-up study on suspension cultures of Taxus chinensis cells for production of taxane diterpene, Enzyme Microb Technol, 27, 714, 10.1016/S0141-0229(00)00276-3 Parchmann, 1997, Induction of 12-oxo-phytodienoic acid in wounded plants and elicited plant cell cultures, Plant Physiol, 115, 1057, 10.1104/pp.115.3.1057 Park, 2000, Rac-related GTP-binding protein in elicitor-induced reactive oxygen generation by suspension-cultured soybean cells, Plant Physiol, 124, 725, 10.1104/pp.124.2.725 Paré, 1998, Concerted biosynthesis of an insect elicitor of plant volatiles, Proc Natl Acad Sci USA, 95, 13971, 10.1073/pnas.95.23.13971 Perrone, 2003, Superoxide release is necessary for phytoalexin accumulation in Nicotiana tabacum cells during the expression of cultivar-race and non-host resistance towards Phytophthora spp, Physiol Mol Plant Pathol, 62, 127, 10.1016/S0885-5765(03)00026-2 Petersen, 2003, Rosmarinic acid, Phytochem, 62, 121, 10.1016/S0031-9422(02)00513-7 Pitta-Alvarez, 2000, The influence of different biotic and abiotic elicitors on the production and profile of tropane alkaloids in hairy root cultures of Brugmansia candida, Enzyme Microb Technol, 26, 252, 10.1016/S0141-0229(99)00137-4 Price, 1994, Oxidative signals in tobacco increase cytosolic calcium, Plant Cell, 6, 1301, 10.1105/tpc.6.9.1301 Puig, 1995, Effect of ethylene on naringin, narirutin and nootkatone accumulation in grapefruit, Planta Med, 61, 283, 10.1055/s-2006-958077 Qi, 2004, A gene cluster for secondary metabolism in oat: implications for the evolution of metabolic diversity in plants, Proc Natl Acad Sci USA, 101, 8233, 10.1073/pnas.0401301101 Rajasekhar, 1999, Early events in the signal pathway for the oxidative burst in soybean cells exposed to avirulent Pseudomonas syringae pv glycinea, Plant Physiol, 120, 1137, 10.1104/pp.120.4.1137 Renelt, 1993, Studies on elicitor recognition and signal transduction in plant defense, J Exp Bot, 44, 257 Roos, 1998, Shifts of intracellular pH distribution as a part of the signal mechanism leading to the elicitation of benzophenanthridine alkaloid biosynthesis, Plant Physiol, 118, 349, 10.1104/pp.118.2.349 Roos, 1999, A redox-dependent, G-protein-coupled phospholipase A of the plasma membrane is involved in the elicitation of alkaloid biosynthesis in Eschscholtzia californica, Biochim Biophys Acta, 1448, 390, 10.1016/S0167-4889(98)00148-7 Saalbach, 1999, The alpha-subunit of a heterotrimeric G-protein from tobacco, NtGP alpha 1, functions in K+ channel regulation in mesophyll cells, J Exp Bot, 50, 53, 10.1093/jexbot/50.330.53 Sakano, 2001, Metabolic regulation of pH in plant cells: role of cytoplasmic pH in defense reaction and secondary metabolism, Int Rev Cytol, 206, 1, 10.1016/S0074-7696(01)06018-1 Saniewski, 1998, Gum formation by methyl jasmonate in tulip shoots is stimulated by ethylene, J Plant Growth Reg, 17, 179, 10.1007/PL00007033 Sato, 2001, Metabolic engineering of plant alkaloid biosynthesis, Proc Natl Acad Sci USA, 98, 367, 10.1073/pnas.011526398 Schaller, 2001, Enzymes of the biosynthesis of octadecanoid-derived signaling molecules, J Exp Bot, 354, 11, 10.1093/jexbot/52.354.11 Scheer, 2002, The systemin receptor SR160 from Lycopersicon esculentum is a member of the LRR receptor kinase family, Proc Natl Acad Sci USA, 99, 9585, 10.1073/pnas.132266499 Scherer, 2002, Down-regulation by elicitors of hosphatidylcholine-hydrolyzing phospholipase C and up-regulation of phospholipase A in plant cells, Biochem Biophys Res Commun, 293, 766, 10.1016/S0006-291X(02)00292-9 Schmelz, 2003, Quantitative relationships between induced jasmonic acid levels and volatile emission in Zea mays during Spodoptera exigua herbivory, Planta, 216, 665, 10.1007/s00425-002-0898-y Schmelz, 2003, Synergistic interactions between volicitin, jasmonic acid and ethylene mediate insect-induced volatile emission in Zea mays, Physiol Plant, 117, 403, 10.1034/j.1399-3054.2003.00054.x Schmelz, 2003, Simultaneous analysis of phytohormones, phytotoxins, and volatile organic compounds in plants, Proc Natl Acad Sci USA, 100, 10552, 10.1073/pnas.1633615100 Shaw, 2003, Nod factor inhibition of reactive oxygen flux in a host legume, Plant Physiol, 132, 2196, 10.1104/pp.103.021113 Shibli, 1997, Headspace ethylene accumulation effects on secondary metabolite production in Vaccinium pahalae cell culture, Plant Growth Reg, 23, 201, 10.1023/A:1005952830019 Shibuya, 2002, Oligosaccharide elicitor signaling: perception and transduction of oligochitin/oligoglucan elicitor in rice, Biol Plant-Microbe Interact, 2, 109 Shoji, 2000, Ethylene suppresses jasmonate-induced gene expression nicotine biosynthesis, Plant Cell Physiol, 41, 1072, 10.1093/pcp/pcd027 Singh, 1998, Interaction of methyl jasmonate, wounding and fungal elicitation during sesquiterpene induction in Hyoscyamus muticus in root cultures, Plant Cell Rep, 17, 391, 10.1007/s002990050412 Smith, 1994, Signal transduction in elicitation of phytoalexin synthesis, Biochem Soc Trans, 22, 414, 10.1042/bst0220414 Stintzi, 2001, Plant defense in the absence of jasmonic acid: the role of cyclopentenones, Proc Natl Acad Sci USA, 98, 12837, 10.1073/pnas.211311098 Subramaniam, 1997, A functional homolog of mammalian protein kinase C participates in the elicitor-induced defense response in potato, Plant Cell, 9, 653, 10.1105/tpc.9.4.653 Suharsono, 2002, The heterotrimeric G protein α-subunit acts upstream of the small GTPase Rac in disease resistance of rice, Proc Natl Acad Sci USA, 99, 13307, 10.1073/pnas.192244099 Sumner, 2003, Plant metabolomics: large-scale phytochemistry in the functional genomics era, Phytochem, 62, 817, 10.1016/S0031-9422(02)00708-2 Szabo, 1999, Fungal elicitor preparations and methyl jasmonate enhance rosmarinic acid accumulation in suspension culture of Coleus blumei, Plant Cell Rep, 18, 484, 10.1007/s002990050608 Taguchi, 2001, Molecular cloning and heterologous expression of novel glucosyltransferases from tobacco cultured cells that have broad substrate specificity and are induced by salicylic acid and auxin, Eur J Biochem, 268, 4086, 10.1046/j.1432-1327.2001.02325.x Tamogami, 1997, Phytoalexin production elicited by exogenously applied jasmonic acid in rice leaves (Oryza sativa L.) is under the control of cytokinins and ascorbic acid, FEBS Lett, 412, 61, 10.1016/S0014-5793(97)00743-6 Tang, 2001, Elicitor induced defense responses in Medicago sativa, New Phytol, 149, 401, 10.1046/j.1469-8137.2001.00062.x Tang, 1996, Initiation of plant disease resistance by physical interaction of AvrPto and Pto kinase, Science, 274, 2060, 10.1126/science.274.5295.2060 Thoma, 2003, Cyclopentenone isoprostanes induced by reactive oxygen species trigger defense gene activation and phytoalexin accumulation in plants, Plant J, 34, 363, 10.1046/j.1365-313X.2003.01730.x Toyoda, 1992, Regulation of polyphosphoinositide metabolism in pea plasma membranes by elicitor and suppressor from a pea pathogen Mycosphaerella pinodes, Plant Cell Physiol, 33, 445 Toyoda, 2000, Potentiation of phytoalexin accumulation in elicitor-treated epicotyls of pea (Pisum sativum) by a diacylglycerol kinase inhibitor, J Phytopathol, 148, 633, 10.1046/j.1439-0434.2000.00568.x Trewavas, 1998, Ca2+ signalling in plant cells: the big network!, Curr Opin Plant Biol, 1, 428, 10.1016/S1369-5266(98)80268-9 Truitt, 2004, A plasma membrane protein from Zea mays binds with the herbivore elicitor volicitin, Plant Cell, 16, 523, 10.1105/tpc.017723 Tumova, 2001, CoCl2 and NiCl2 elicitation and flavonoid production in Ononis arvensis L. culture in vitro, Acta Pharm, 51, 159 Turlings, 1990, Exploitation of herbivore-induced plant odors by host-seeking parasitic wasps, Science, 250, 1251, 10.1126/science.250.4985.1251 Umemoto, 1997, The structure and function of a soybean β-glucan-elicitor-binding protein, Proc Natl Acad Sci USA, 94, 1029, 10.1073/pnas.94.3.1029 Umemura, 2002, Elicitor activity of cerebroside, a sphingolipid elicitor, in cell suspension cultures of rice, Plant Cell Physiol, 43, 778, 10.1093/pcp/pcf090 van der Fits, 2000, ORCA3, a jasmonate-responsive transcriptional regulator of plant primary and secondary metabolism, Science, 289, 295, 10.1126/science.289.5477.295 Vasconsuelo, 2003, Involvement of the PLC/PKC pathway in chitosan-induced anthraquinone production by Rubia tinctorum L. cell cultures, Plant Sci, 165, 429, 10.1016/S0168-9452(03)00208-5 Vasconsuelo, 2004, Signal transduction events mediating chitosan stimulation of anthraquinone synthesis in Rubia tinctorum, Plant Sci, 166, 405, 10.1016/j.plantsci.2003.10.007 Vera-Estrella, 1994, Plant defense response to fungal pathogens II: G-protein mediate changes in host plasma membrane redox reactions, Plant Physiol, 106, 97, 10.1104/pp.106.1.97 Verpoorte, 2002, Engineering secondary metabolite production in plants, Curr Opin Biotechnol, 13, 181, 10.1016/S0958-1669(02)00308-7 Viehveger, 2002, Elicitor-activated phospholipase A2 generates lysophosphatidylcholines that mobilize the vacuolar H+ pool for pH signaling via the activation of Na+-dependent proton fluxes, Plant Cell, 14, 1509, 10.1105/tpc.002329 Volotovski, 1998, Second messengers mediate increases in cytosolic calcium in tobacco protoplasts, Plant Physiol, 117, 1023, 10.1104/pp.117.3.1023 Walker, 2002, Jasmonic acid-induced hypericin production in cell suspension cultures of Hypericum perforatum L, Phytochem, 60, 289, 10.1016/S0031-9422(02)00074-2 Walker, 2003, Metabolic profiling of root exudates of Arabidopsis thaliana, J Agr Food Chem, 51, 2548, 10.1021/jf021166h Walton, 1993, Cell Signal, 5, 345, 10.1016/0898-6568(93)90026-I Wang, 2002, Phospholipase D in hormonal and stress signaling, Curr Opin Plant Biol, 5, 408, 10.1016/S1369-5266(02)00283-2 Wang, 2001, G protein regulation of ion channels and abscisic acid signaling in Arabidopsis guard cells, Science, 292, 2070, 10.1126/science.1059046 Wang, 2002, Ethylene biosynthesis and signaling networks, Plant Cell, 14, S131, 10.1105/tpc.001768 White, 2003, Calcium in plants, Ann Bot, 92, 487, 10.1093/aob/mcg164 Wu, 2004, Oxidative burst, jasmonic acid biosynthesis, and taxol production induced by low-energy ultrasound in Taxus chinensis cell suspension cultures, Biotechnol Bioeng, 85, 714, 10.1002/bit.10911 Xu M, Dong J. Elicitor-induced nitric oxide burst is essential for triggering catharanthine synthesis in Catharanthus roseus suspension cells. Appl Microbiol Biotechnolin in press. Xu, 1994, Plant defense genes are synergistically induced by ethylene and methyl jasmonate, Plant Cell, 6, 1077, 10.1105/tpc.6.8.1077 Xu, 2004, Characterization of GaWRKY1, a cotton transcription factor that regulates the sesquiterpene synthase gene (+)-δ-cadinene synthase-A, Plant Physiol, 135, 507, 10.1104/pp.104.038612 Yamaguchi, 2002, Two purified oligosaccharide elicitors, N-acetylchitohepatose and tetraglucosyl glucitol, derived from Magnaporthe grisea cell walls, synergistically activate biosynthesis of phytoalexin in suspension-cultured rice cells, J Plant Physiol, 159, 1147, 10.1078/0176-1617-00877 Yamaguchi, 2004, Activation of phospholipase D induced by hydrogen peroxide in suspension-cultured rice cells, Plant Cell Physiol, 45, 1261, 10.1093/pcp/pch150 Yang, 2002, Small GTPases: versatile signaling switches in plants, Plant Cell, 14, S375, 10.1105/tpc.001065 Yang, 2002, A calmodulin-binding/CGCG box DNA-binding protein family involved in multiple signaling pathways in plants, J Biol Chem, 277, 45049, 10.1074/jbc.M207941200 Yang, 2003, Novel gene expression profiles define the metabolic and physiological processes characteristic of wood and its extractive formation in a hardwood tree species Robinia pseudoacacia, Plant Mol Biol, 52, 935, 10.1023/A:1025445427284 Yang, 2004, Analysis of the involvement of hydroxyanthranilate hydroxycinnamoyltransferase and caffeoyl-CoA 3-O-methyltransferase in phytoalexin biosynthesis in oat, Mol Plant-Microbe Interact, 17, 81, 10.1094/MPMI.2004.17.1.81 Yazaki, 2002, Geranyl diphosphate: 4-hydroxybenzoate geranyltransferase from Lithospermum erythrorhizon, J Biol Chem, 277, 6240, 10.1074/jbc.M106387200 Yoshioka, 2001, Induction of plant gp91 phox homolog by fungal cell wall, arachidonic acid, and salicylic acid in potato, Mol Plant-Microbe Interact, 14, 725, 10.1094/MPMI.2001.14.6.725 Yukimune, 1996, Methyl jasmonate-induced overproduction of paclitaxel and baccatin III in Taxus cell suspension cultures, Nature Biotechnol, 14, 1129, 10.1038/nbt0996-1129 Zeringue, 1992, Effects of C6-C10 alkenals and alkanals on eliciting a defense response in the developing cotton ball, Phytochem, 31, 2305, 10.1016/0031-9422(92)83269-5 Zhang, 2004, Enhancement of tanshinone production in Salvia miltiorrhiza hairy root culture by Ag+ elicitation and nutrient feeding, Planta Med, 70, 147, 10.1055/s-2004-815492 Zhao, 2003, Multiple signaling pathways mediate fungal elicitor induced β-thujaplicin accumulation in Cupressus lusitanica cell cultures, J Exp Bot, 54, 647, 10.1093/jxb/erg062 Zhao, 2003, Peroxidases are involved in the biosynthesis and biodegradation of β-thujaplicin in fungal elicitor-treated Cupressus lusitanica suspension cultures, New Phytol, 159, 719, 10.1046/j.1469-8137.2003.00841.x Zhao, 2004, Arabidopsis phospholipase Dα1 interacts with the heterotrimeric G-protein α-subunit through a motif analogous to the DRY motif in G-protein-coupled receptors, J Biol Chem, 279, 1794, 10.1074/jbc.M309529200 Zhao, 2000, Improved indole alkaloid production in Catharanthus roseus suspension cell cultures by various chemicals, Biotechnol Lett, 22, 1221, 10.1023/A:1005696929724 Zhao, 2001, Improved beta-thujaplicin production in Cupressus lusitanica suspension cultures by fungal elicitor and methyl jasmonate, Appl Microbiol Biotechnol, 55, 301, 10.1007/s002530000555 Zhao, 2001, Elicitor-induced indole alkaloid biosynthesis in Catharanthus roseus cell cultures is related to Ca2+-influx and the oxidative burst, Plant Sci, 161, 423, 10.1016/S0168-9452(01)00422-8 Zhao, 2001, Enhanced catharanthine production in Catharanthus roseus cell cultures by combined elicitor treatment in shake flasks and bioreactors, Enzyme Microb Technol, 28, 673, 10.1016/S0141-0229(01)00306-4 Zhao, 2004, Involvement of cAMP signaling pathway in elicitor-induced phytoalecin accumulation in Cupressus lusitanica cell cultures, New Phytol, 161, 723, 10.1111/j.1469-8137.2004.00976.x Zhao, 2004, Rapid metabolism of phosphoinositides and its possible role in phytoalexin biosynthesis in elicitor-treated Cupressus lusitanica cell cultures, Planta, 129, 121, 10.1007/s00425-003-1198-x Zhao, 2004, Jasmonate and ethylene signaling pathways and their interaction are integral parts of the elicitor signal transduction leading to phytoalexin biosynthesis in Cupressus lusitanica cell culture, J Exp Bot, 55, 1003, 10.1093/jxb/erh127 Zhao, 2005, The oxidative stress in plant cell culture: a role in production of β-thujaplicin by Cupressus lusitanica cell cultures, Biotechnol Bioeng, 10.1002/bit.20465 Zhong, 2001, Biochemical engineering of the production of plant-specific secondary metabolites by cell cultures, Adv Biochem Eng Biotechnol, 72, 1