Vacuum Erection Devices Revisited: its Emerging Role in the Treatment of Erectile Dysfunction and Early Penile Rehabilitation Following Prostate Cancer Therapy

The Journal of Sexual Medicine - Tập 9 Số 4 - Trang 1182-1189 - 2012
Geetu Pahlajani1, Rupesh Raina2,1, Stephen E. Jones1, Marwan Ali1, Craig D. Zippe1
1Department of Regional Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA
2Department of Internal Medicine and Pediatrics, Metro Health Medical Center, Case Western Reserve University , Cleveland, OH , USA

Tóm tắt

ABSTRACT Introduction Vacuum erection devices (VEDs) are becoming first-line therapies for the treatment of erectile dysfunction and preservation (rehabilitation) of erectile function following treatment for prostate cancer. Currently, there is limited efficacy of the use of phosphodiesterase type 5 inhibitors in elderly patients, or patients with moderate to severe diabetes, hypertension, and coronary artery disease. Aim The article aims to study the role of VED in patients following prostate cancer therapy. Results Alternative therapies such as VED have emerged as one of the primary options for patients refractory to oral therapy. VED has also been successfully used in combination treatment with oral therapy and penile injections. More recently, there has been interest in the use of VED in early intervention protocols to encourage corporeal rehabilitation and prevention of postradical prostatectomy veno-occlusive dysfunction. This is evident by the preservation of penile length and girth that is seen with early use of the VED following radical prostatectomy. There are ongoing studies to help preserve penile length and girth with early use of VED following prostate brachytherapy and external beam radiation for prostate cancer. Recently, there has also been interest in the use of VED to help maintain penile length following surgical correction of Peyronie’s disease and to increase penile size prior to implantation of the penile prosthesis. Conclusion VEDs can be one of the options for penile rehabilitation after prostate cancer therapy.

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Tài liệu tham khảo

Nandipati, 2006, Erectile dysfunction following radical retropubic prostatectomy: Epidemiology, pathophysiology and pharmacological management, Drugs Aging, 23, 101, 10.2165/00002512-200623020-00002

Stone, 2007, Long term urinary, sexual, and rectal morbidity in patients treated with Iodine-125 prostate brachytherapy followed up for a minimum of 5 years, Urology, 69, 338, 10.1016/j.urology.2006.10.001

Levine, 2001, Vacuum constriction and external erection devices in erectile dysfunction, Urol Clin North Am, 28, 335, 10.1016/S0094-0143(05)70142-7

Raina, 2004, Efficacy and factors associated with successful outcome of sildenafil citrate use following radical prostatectomy, Urology, 63, 960, 10.1016/j.urology.2003.12.012

Raina, 2005, Sildenafil citrate and vacuum constriction device combination enhances sexual satisfaction in erectile dysfunction after radical prostatectomy, Urology, 65, 360, 10.1016/j.urology.2004.09.013

Bratton, 2002, Vacuum erection device use in elderly men: A possible severe complication, J Am Board Fam Pract, 15, 501

Utida, 2005, Male infertility in spinal cord trauma, Int Braz J Urol, 31, 375, 10.1590/S1677-55382005000400013

Sidi, 1992, Clinical trial of a simplified vacuum erection device for impotence treatment, Urology, 39, 526, 10.1016/0090-4295(92)90008-K

Nadig, 1986, Noninvasive device to produce and maintain an erection-like state, Urology, 27, 126, 10.1016/0090-4295(86)90368-7

Vrijhof, 1994, Vacuum constriction devices in erectile dysfunction: Acceptance and effectiveness in patients with impotence of organic or mixed etiology, Br J Urol, 74, 102, 10.1111/j.1464-410X.1994.tb16555.x

Bosshardt, 1995, Objective measurement of the effectiveness, therapeutic success and dynamic mechanisms of the vacuum device, Br J Urol, 75, 786, 10.1111/j.1464-410X.1995.tb07392.x

Baltaci, 1995, Treating erectile dysfunction with a vacuum tumescence device: A retrospective analysis of acceptance and satisfaction, Br J Urol, 76, 757, 10.1111/j.1464-410X.1995.tb00769.x

Gontero, 2004, Proerectile pharmacological prophylaxis following nerve-sparing radical prostatectomy (NSRP), Prostate Cancer Prostatic Dis, 7, 223, 10.1038/sj.pcan.4500737

Zippe, 2006, Sexual dysfunction after pelvic surgery, Int J Impot Res, 18, 1, 10.1038/sj.ijir.3901353

Lewis, 1997, External vacuum therapy for erectile dysfunction: Use and results, World J Urol, 15, 78, 10.1007/BF01275162

Turner, 1991, External vacuum devices in the treatment of erectile dysfunction: A one-year study of sexual and psychosocial impact, J Sex Marital Ther, 17, 81, 10.1080/00926239108404950

Van Thillo, 1992, The vacuum erection device. A noninvasive treatment for impotence, Acta Urol Belg, 60, 9

Meuleman, 1993, [Experiences with a vacuum apparatus in the treatment of erection disorders], Ned Tijdschr Geneeskd, 137, 412

Derouet, 1999, Treatment of erectile dysfunction with external vacuum devices, Andrologia, 31, 89

Mulhall, 1997, Intracavernosal injection therapy: A practical guide, Tech Urol, 3, 129

Purvis, 1999, Intracavernosal therapy for erectile failure—Impact of treatment and reasons for drop-out and dissatisfaction, Int J Impot Res, 11, 287, 10.1038/sj.ijir.3900435

Sundaram, 1997, Long-term follow-up of patients receiving injection therapy for erectile dysfunction, Urology, 49, 932, 10.1016/S0090-4295(97)00079-4

Moore, 2005, Indirect comparison of interventions using published randomized trials: Systematic review of PDE-5 inhibitors for erectile dysfunction, BMC Urol, 5, 18, 10.1186/1471-2490-5-18

McMahon, 2000, Erectile dysfunction, Med J Aust, 173, 492, 10.5694/j.1326-5377.2000.tb139304.x

Montague, 2003, Contemporary aspects of penile prosthesis implantation, Urol Int, 70, 141, 10.1159/000068189

Wagner, 1998, Update on male erectile dysfunction, BMJ, 316, 678, 10.1136/bmj.316.7132.678

Nunez Mora, 2000, [Treatment of erectile dysfunction with vacuum devices], Arch Esp Urol, 53, 819

Lewis, 2005, The role of vacuum device therapy in the management of erectile dysfunction, US Kid Urol, 2, 112

Sperling, 2003, [New treatment options for erectile dysfunction. Pharmacologic and non-pharmacologic options], Herz, 28, 314, 10.1007/s00059-003-2472-1

Gauthier, 2000, Relative efficacy of sildenafil compared to other treatment options for erectile dysfunction, South Med J, 93, 962, 10.1097/00007611-200093100-00003

Shabsigh, 2000, Intracavernous alprostadil alfadex (EDEX/VIRIDAL) is effective and safe in patients with erectile dysfunction after failing sildenafil (Viagra), Urology, 55, 477, 10.1016/S0090-4295(99)00612-3

McMahon, 1991, Comparison of the response to the intracavernosal injection of a combination of papaverine and phentolamine, prostaglandin E1 alone and a combination of all three in the management of impotence, Int J Impot Res, 3, 133

Carson, 2003, Penile prostheses: Are they still relevant?, BJU Int, 91, 176, 10.1046/j.1464-410X.2003.t01-1-03064.x

Chen, 2001, Sildenafil versus vacuum erection device: Patient preference, J Urol, 166, 1779, 10.1016/S0022-5347(05)65674-1

Moul, 1989, Negative pressure devices in the explanted penile prosthesis population, J Urol, 142, 729, 10.1016/S0022-5347(17)38869-9

Chen, 2004, Concomitant use of sildenafil and a vacuum entrapment device for the treatment of erectile dysfunction, J Urol, 171, 292, 10.1097/01.ju.0000098460.02560.fe

Soderdahl, 1997, The use of an external vacuum device to augment a penile prosthesis, Tech Urol, 3, 100

Israilov, 2005, Evaluation of a progressive treatment program for erectile dysfunction in patients with diabetes mellitus, Int J Impot Res, 17, 431, 10.1038/sj.ijir.3901337

Ciancio, 2000, Penile fibrotic changes after radical retropubic prostatectomy, BJU Int, 85, 101, 10.1046/j.1464-410x.2000.00364.x

Munding, 2001, Pilot study of changes in stretched penile length 3 months after radical retropubic prostatectomy, Urology, 58, 567, 10.1016/S0090-4295(01)01270-5

Savoie, 2003, A prospective study measuring penile length in men treated with radical prostatectomy for prostrate cancer, J Urol, 169, 1462, 10.1097/01.ju.0000053720.93303.33

Dalkin, 2007, Preservation of penile length after radical prostatectomy (RP) Early intervention with a vacuum erection device (VED)

Kohler, 2007, A pilot study of early use of vacuum erection device after radical retropubic prostatectomy, BJU, 100, 858, 10.1111/j.1464-410X.2007.07161.x

Zippe, 2007, Penile rehabilitation following radical prostatectomy: Role of early intervention and chronic therapy, Urol Clin North Am, 34, 601, 10.1016/j.ucl.2007.08.012

Monga, 2006, Early use of vacuum constriction device following radical retropubic prostatectomy: A randomized clinical trial, Urology, 68, 262, 10.1016/j.urology.2006.08.776

McCullough, 2001, Prevention and management of erectile dysfunction following radical prostatectomy, Urol Clin North Am, 28, 613, 10.1016/S0094-0143(05)70166-X

Pahlajani, 2008, Early intervention with PDE-5 inhibitors following prostate brachytherapy improves subsequent erectile function, 10.1016/j.ijrobp.2008.06.1468

Lue, 1999, Lengthening shortened penis caused by Peyronie’s disease using circular venous grafting and daily stretching with a vacuum erection device, J Urol, 161, 1141, 10.1016/S0022-5347(01)61613-6

Colombo, 2000, Early rehabilitation with vacuum device following sphenoid graft surgery for Personae’s disease, Eur Urol, 3, 180, 10.1016/S1569-9056(02)80703-5

Sellers, 2008, Vacuum protocol and cylinders that lengthen allow implantation of longer, inflatable prosthesis

Mulhall, 2007, Penile rehabilitation should become the norm for radical prostatectomy patients, J Sex Med, 4, 538, 10.1111/j.1743-6109.2007.00486.x

Tan, 2000, Economic cost of male erectile dysfunction using a decision analytic model: For a hypothetical managed-care plan of 100,000 members, Pharmacoeconomics, 17, 77, 10.2165/00019053-200017010-00006

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The Journal of Sexual Medicine

Tập 9 Số 4

1182-1189

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