Monoclonal antibodies with neutralizing activity segregate isolates of bovine viral diarrhea virus into groups

Archives of Virology - Tập 99 - Trang 117-123 - 1988
S. Bolin1, V. Moennig2, N. E. Kelso Gourley2, J. Ridpath1
1Virology Cattle Research Unit, National Animal Disease Center, USDA, ARS, Ames, U.S.A.
2Department of Veterinary Microbiology, College of Veterinary Medicine, Iowa State University, Ames, U.S.A.

Tóm tắt

Isolates of bovine viral diarrhea (BVD) virus were differentiated by monoclonal antibodies (MoAbs) reactive with the 56kD viral polypeptide. Patterns of neutralizing activity of the MoAbs indicate that multiple epitopes are involved in virus neutralization.

Tài liệu tham khảo

Bolin SR, McClurkin AW, Cutlip RC, Coria MF (1985) Response of cattle persistently infected with noncytopathic bovine viral diarrhea virus to vaccination for bovine viral diarrhea and to subsequent challenge exposure with cytopathic bovine viral diarrhea virus. Am J Vet Res 46: 2467–2470 Coria MF, McClurkin AW (1978) Specific immune tolerance in an apparently healthy bull persistently infected with bovine viral diarrhea virus. J Am Vet Med Assoc 172: 449–451 Donis RO, Dubovi EJ (1987) Characterization of bovine viral diarrhea-mucosal disease virus-specific proteins in bovine cells. J Gen Virol 68: 1597–1605 Donis RO, Dubovi EJ (1987) Differences in virus-induced polypeptides in cells infected by cytopathic and noncytopathic biotypes of bovine virus diarrhea-mucosal disease virus. Virology 158: 168–173 Donis RO, Dubovi EJ (1987) Glycoproteins of bovine viral diarrhea-mucosal disease virus in infected bovine cells. J Gen Virol 68: 1607–1616 Gillespie JH, Baker JA, McEntee K (1960) A cytopathogenic strain of virus diarrhea virus. Cornell Vet 50: 73–79 Gillespie JH, Coggins L, Thompson J, Baker JA (1961) Comparison by neutralization tests of strains of virus isolated from virus diarrhea and mucosal disease. Cornell Vet 51: 155–159 Gould EA, Buckley A, Cammack N, Barrett ADT, Clegg JCS, Ishak R, Varma MGR (1985) Examination of the immunological relationships between flaviviruses using yellow fever virus monoclonal antibodies. J Gen Virol 66: 1369–1382 Hafez SM, Liess B, Frey HR (1976) Studies on the natural occurrence of neutralizing antibodies against six strains of bovine viral diarrhea virus in field sera of cattle. Zentralbl Veterinarmed [B] 23: 669–677 Howard CJ, Brownlie J, Clarke MC (1987) Comparison by the neutralization assay of pairs of non-cytopathogenic and cytopathogenic strains of bovine virus diarrhea virus isolated from cases of mucosal disease. Vet Microbiol 13: 361–369 Inaba Y, Omori T, Kumagai T (1963) Detection and measurement of non-cytopathogenic strains of virus diarrhea of cattle by the END method. Arch Ges Virusforsch 13: 425–429 Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680–686 Lee KM, Gillespie JH (1957) Propagation of virus diarrhea virus of cattle in tissue culture. Am J Vet Res 18: 952–953 Liess B, Frey HR, Prager D (1977) Antibody response of pigs following experimental infections with strains of hog cholera, bovine viral diarrhea virus. In: Hog cholera/classical swine fever and African swine fever. EUR 5904 EN: 200–213 Liess B, Frey HR, Orban S, Hafez SM (1983) Bovine virus diarrhea-mucosal disease: persistent BVD field virus infections in serologically selected cattle. DTW 990: 261–266 Matthaeus W (1979) Detection of three polypeptides in preparations of bovine viral diarrhea virus. Arch Virol 59: 299–305 McClurkin AW, Littledike ET, Cutlip RC, Frank GH, Coria MF, Bolin SR (1984) Production of cattle immunotolerant to bovine viral diarrhea virus. Can J Comp Med 48: 156–161 Peters W, Greiser-Wilke I, Moennig V, Liess B (1986) Preliminary serological characterization of bovine viral diarrhea virus strains using monoclonal antibodies. Vet Microbiol 12: 195–200 Purchio AF, Larson R, Collett MS (1984) Characterization of bovine viral diarrhea viral proteins. J Virol 50: 666–669 Rossi CR, Kiesel GK (1971) Microtiter tests for detecting antibody in bovine serum to parainfluenza 3 virus, infectious bovine rhinotracheitis virus, and bovine virus diarrhea virus. Appl Microbiol 22: 32–36 Schlesinger JJ, Brandriss MW, Monath TP (1983) Monoclonal antibodies distinguish between wild and vaccine strains of yellow fever virus by neutralization, hemagglutination, and immune precipitation of the virus envelope protein. Virology 125: 8–17 Taggart RT, Samloff IM (1983) Stable antibody-producing murine hybridomas. Science 219: 1228–1230 Whetstone CA, Bunn TO, Emmons RW, Wiktor TJ (1984) Use of monoclonal antibodies to confirm vaccine-induced rabies in ten dogs, two cats, and one fox. J Am Vet Med Assoc 185: 285–288