Lerman, 2007, Translational research in medication development for nicotine dependence, Nat Rev Drug Discov, 6, 746, 10.1038/nrd2361
Conn, 2008, Opportunities and challenges of psychiatric drug discovery: Roles for scientists in academic, industry, and government settings, Neuropsychopharmacology, 33, 2048, 10.1038/sj.npp.1301638
Hyman, 2003, Medicine, Science, 299, 350, 10.1126/science.1077141
Evans, 2009, Nicotine self-medication of cognitive-attentional processing, Addict Biol, 14, 32, 10.1111/j.1369-1600.2008.00130.x
Jacobsen, 2005, Effects of smoking and smoking abstinence on cognition in adolescent tobacco smokers, Biol Psychiatry, 57, 56, 10.1016/j.biopsych.2004.10.022
Mendrek, 2006, Working memory in cigarette smokers: Comparison to non-smokers and effects of abstinence, Addict Behav, 31, 833, 10.1016/j.addbeh.2005.06.009
Xu, 2005, Brain activity in cigarette smokers performing a working memory task: Effect of smoking abstinence, Biol Psychiatry, 58, 143, 10.1016/j.biopsych.2005.03.028
Davis, 2005, Withdrawal from chronic nicotine administration impairs contextual fear conditioning in C57BL/6 mice, J Neurosci, 25, 8708, 10.1523/JNEUROSCI.2853-05.2005
Myers, 2008, Dose-related enhancement of mood and cognition in smokers administered nicotine nasal spray, Neuropsychopharmacology, 33, 588, 10.1038/sj.npp.1301425
Hughes, 2007, Measurement of the effects of abstinence from tobacco: A qualitative review, Psychol Addict Behav, 21, 127, 10.1037/0893-164X.21.2.127
Ward, 2001, Self-reported abstinence effects in the first month after smoking cessation, Addict Behav, 26, 311, 10.1016/S0306-4603(00)00107-6
Patterson, 2010, Working memory deficits predict short-term smoking resumption following brief abstinence, Drug Alcohol Depend, 106, 61, 10.1016/j.drugalcdep.2009.07.020
Cosgrove, 2009, Beta2-nicotinic acetylcholine receptor availability during acute and prolonged abstinence from tobacco smoking, Arch Gen Psychiatry, 66, 666, 10.1001/archgenpsychiatry.2009.41
Gotti, 2006, Brain nicotinic acetylcholine receptors: Native subtypes and their relevance, Trends Pharmacol Sci, 27, 482, 10.1016/j.tips.2006.07.004
Sarter, 2009, nAChR agonist-induced cognition enhancement: Integration of cognitive and neuronal mechanisms, Biochem Pharmacol, 78, 658, 10.1016/j.bcp.2009.04.019
Cannady, 2009, Nicotinic antagonist effects in the mediodorsal thalamic nucleus: Regional heterogeneity of nicotinic receptor involvement in cognitive function, Biochem Pharmacol, 78, 788, 10.1016/j.bcp.2009.05.021
Levin, 2006, Nicotinic effects on cognitive function: Behavioral characterization, pharmacological specification, and anatomic localization, Psychopharmacology (Berl), 184, 523, 10.1007/s00213-005-0164-7
Kenney, 2008, Modulation of hippocampus-dependent learning and synaptic plasticity by nicotine, Mol Neurobiol, 38, 101, 10.1007/s12035-008-8037-9
Mansvelder, 2000, Long-term potentiation of excitatory inputs to brain reward areas by nicotine, Neuron, 27, 349, 10.1016/S0896-6273(00)00042-8
Livingstone, 2009, Nicotinic acetylcholine receptors and the ascending dopamine pathways, Biochem Pharmacol, 78, 744, 10.1016/j.bcp.2009.06.004
Brody, 2009, Ventral striatal dopamine release in response to smoking a regular vs a denicotinized cigarette, Neuropsychopharmacology, 34, 282, 10.1038/npp.2008.87
Loughead, 2009, Effect of abstinence challenge on brain function and cognition in smokers differs by COMT genotype, Mol Psychiatry, 14, 820, 10.1038/mp.2008.132
Rollema, 2007, Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist Varenicline, an effective smoking cessation aid, Neuropharmacology, 52, 985, 10.1016/j.neuropharm.2006.10.016
Mihalak, 2006, Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors, Mol Pharmacol, 70, 801, 10.1124/mol.106.025130
Rollema, 2009, Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition, Biochem Pharmacol, 78, 813, 10.1016/j.bcp.2009.05.033
Raybuck, 2008, Varenicline ameliorates nicotine withdrawal-induced learning deficits in C57BL/6 mice, Behav Neurosci, 122, 1166, 10.1037/a0012601
Patterson, 2009, Varenicline improves mood and cognition during smoking abstinence, Biol Psychiatry, 65, 144, 10.1016/j.biopsych.2008.08.028
Owen, 2005, N-back working memory paradigm: A meta-analysis of normative functional neuroimaging studies, Hum Brain Mapp, 25, 46, 10.1002/hbm.20131
McClernon, 2008, Individual differences in nicotine dependence, withdrawal symptoms, and sex predict transient fMRI-BOLD responses to smoking cues, Neuropsychopharmacology, 33, 2148, 10.1038/sj.npp.1301618
Rose, 2007, Regional brain activity correlates of nicotine dependence, Neuropsychopharmacology, 32, 2441, 10.1038/sj.npp.1301379
Azizian, 2008, Severity of nicotine dependence moderates performance on perceptual-motor tests of attention, Nicotine Tob Res, 10, 599, 10.1080/14622200801979159
Heatherton, 1991, The Fagerstrom Test for Nicotine Dependence: A revision of the Fagerstrom Tolerance Questionnaire, Br J Addict, 86, 1119, 10.1111/j.1360-0443.1991.tb01879.x
Schnoll, 2009, Nicotine metabolic rate predicts successful smoking cessation with transdermal nicotine: A validation study, Pharmacol Biochem Behav, 92, 6, 10.1016/j.pbb.2008.10.016
Sheehan, 1998, The Mini-International Neuropsychiatric Interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10, J Clin Psychiatry, 59, 22
Lerman, 2004, Individualizing nicotine replacement therapy for the treatment of tobacco dependence: A randomized trial, Ann Intern Med, 140, 426, 10.7326/0003-4819-140-6-200403160-00009
2002, Biochemical verification of tobacco use and cessation, Nicotine Tob Res, 4, 149, 10.1080/14622200210123581
Ragland, 2002, Working memory for complex figures: An fMRI comparison of letter and fractal n-back tasks, Neuropsychology, 16, 370, 10.1037/0894-4105.16.3.370
Zaitsev M, Hennig J, Speck O (2003) Automated onlnie EPI distortion correction for fMRI applications [abstract]. In: Proceedings of the 11th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Toronto, ON, Canada, July 10–16, 2003, 1042.
Zeng, 2002, Image distortion correction in EPI: Comparison of field mapping with point spread function mapping, Magn Reson Med, 48, 137, 10.1002/mrm.10200
Woolrich, 2001, Temporal autocorrelation in univariate linear modeling of FMRI data, Neuroimage, 14, 1370, 10.1006/nimg.2001.0931
Worsley, 2001, Statistical analysis of activation images, 251
Ernst, 2001, Effect of nicotine on brain activation during performance of a working memory task, Proc Natl Acad Sci U S A, 98, 4728, 10.1073/pnas.061369098
Beuten, 2006, Significant association of catechol-O-methyltransferase (COMT) haplotypes with nicotine dependence in male and female smokers of two ethnic populations, Neuropsychopharmacology, 31, 675, 10.1038/sj.npp.1300997
Colilla, 2005, Association of catechol-O-methyltransferase with smoking cessation in two independent studies of women, Pharmacogenet Genomics, 15, 393, 10.1097/01213011-200506000-00004
Smolka, 2006, Severity of nicotine dependence modulates cue-induced brain activity in regions involved in motor preparation and imagery, Psychopharmacology (Berl), 184, 577, 10.1007/s00213-005-0080-x
Yalachkov, 2009, Brain regions related to tool use and action knowledge reflect nicotine dependence, J Neurosci, 29, 4922, 10.1523/JNEUROSCI.4891-08.2009
Goldberg, 2004, Genes and the parsing of cognitive processes, Trends Cogn Sci, 8, 325, 10.1016/j.tics.2004.05.011
Williams, 2006, Under the curve: Critical issues for elucidating D1 receptor function in working memory, Neuroscience, 139, 263, 10.1016/j.neuroscience.2005.09.028
Gentry, 2003, Effects of prolonged nicotinic ligand exposure on function of heterologously expressed, human alpha4beta2- and alpha4beta4-nicotinic acetylcholine receptors, J Pharmacol Exp Ther, 304, 206, 10.1124/jpet.102.041756
Levin, 2009, Nicotinic alpha7- or beta2-containing receptor knockout: Effects on radial-arm maze learning and long-term nicotine consumption in mice, Behav Brain Res, 196, 207, 10.1016/j.bbr.2008.08.048
Cincotta, 2008, Selective nicotinic acetylcholine receptor agonists: Potential therapies for neuropsychiatric disorders with cognitive dysfunction, Curr Opin Investig Drugs, 9, 47
Poorthuis, 2009, Nicotinic actions on neuronal networks for cognition: General principles and long-term consequences, Biochem Pharmacol, 78, 668, 10.1016/j.bcp.2009.04.031
Livingstone, 2009, Alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate dopamine release in vitro and in vivo in the rat prefrontal cortex, Eur J Neurosci, 29, 539, 10.1111/j.1460-9568.2009.06613.x
Castner, 2004, Animal models of working memory: Insights for targeting cognitive dysfunction in schizophrenia, Psychopharmacology (Berl), 174, 111, 10.1007/s00213-003-1710-9
Savitz, 2006, The molecular genetics of cognition: Dopamine, COMT and BDNF, Genes Brain Behav, 5, 311, 10.1111/j.1601-183X.2005.00163.x
Papaleo, 2008, Genetic dissection of the role of catechol-O-methyltransferase in cognition and stress reactivity in mice, J Neurosci, 28, 8709, 10.1523/JNEUROSCI.2077-08.2008
Hahn, 2009, Performance effects of nicotine during selective attention, divided attention, and simple stimulus detection: An fMRI study, Cereb Cortex, 19, 1990, 10.1093/cercor/bhn226
Thiel, 2007, Visual and auditory alertness: Modality-specific and supramodal neural mechanisms and their modulation by nicotine, J Neurophysiol, 97, 2758, 10.1152/jn.00017.2007
Hahn, 2007, Nicotine enhances visuospatial attention by deactivating areas of the resting brain default network, J Neurosci, 27, 3477, 10.1523/JNEUROSCI.5129-06.2007
Teneggi, 2002, Smokers deprived of cigarettes for 72 h: Effect of nicotine patches on craving and withdrawal, Psychopharmacology (Berl), 164, 177, 10.1007/s00213-002-1176-1
Perkins, 2006, Medication screening for smoking cessation: A proposal for new methodologies, Psychopharmacology (Berl), 184, 628, 10.1007/s00213-005-0105-5
Perkins, 2008, Development of procedures for early screening of smoking cessation medications in humans, Clin Pharmacol Ther, 84, 216, 10.1038/clpt.2008.30
Jacobsen, 2006, C957T polymorphism of the dopamine D2 receptor gene modulates the effect of nicotine on working memory performance and cortical processing efficiency, Psychopharmacology (Berl), 188, 530, 10.1007/s00213-006-0469-1
Moss, 2009, Prefrontal cognitive dysfunction is associated with tobacco dependence treatment failure in smokers with schizophrenia, Drug Alcohol Depend, 104, 94, 10.1016/j.drugalcdep.2009.04.005
Van Essen, 2001, An integrated software system for surface-based analyses of cerebral cortex, J Am Med Inform Assoc, 8, 443, 10.1136/jamia.2001.0080443