Subcellular engineering of lipase dependent pathways directed towards lipid related organelles for highly effectively compartmentalized biosynthesis of triacylglycerol derived products in Yarrowia lipolytica
Tài liệu tham khảo
Abdel-Mawgoud, 2018, Metabolic engineering in the host Yarrowia lipolytica, Metab. Eng., 50, 192, 10.1016/j.ymben.2018.07.016
Adrio, 2017, Oleaginous yeasts: promising platforms for the production of oleochemicals and biofuels, Biotechnol. Bioeng., 114, 1915, 10.1002/bit.26337
Agapakis, 2012, Natural strategies for the spatial optimization of metabolism in synthetic biology, Nat. Chem. Biol., 8, 527, 10.1038/nchembio.975
Ageitos, 2011, Oily yeasts as oleaginous cell factories, Appl. Microbiol. Biotechnol., 90, 1219, 10.1007/s00253-011-3200-z
Aguieiras, 2015, Current status and new developments of biodiesel production using fungal lipases: a review, Fuel, 159, 52, 10.1016/j.fuel.2015.06.064
Avalos, 2013, Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols, Nat. Biotechnol., 31, 335, 10.1038/nbt.2509
Blazeck, 2014, Harnessing Yarrowia lipolytica lipogenesis to create a platform for lipid and biofuel production, Nat. Commun., 5, 3131, 10.1038/ncomms4131
Chen, 2015, Combinatorial metabolic engineering of Saccharomyces cerevisiae for terminal alkene production, Metab. Eng., 31, 53, 10.1016/j.ymben.2015.06.009
Darvishi, 2017, Yarrowia lipolytica as a workhorse for biofuel production, Biochem. Eng. J., 127, 87, 10.1016/j.bej.2017.08.013
DeLoache, 2016, Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways, Nat. Commun., 7, 11152, 10.1038/ncomms11152
Dourou, 2018, Critical steps in carbon metabolism affecting lipid accumulation and their regulation in oleaginous microorganisms, Appl. Microbiol. Biotechnol., 102, 2509, 10.1007/s00253-018-8813-z
Dulermo, 2011, Involvement of the G3P shuttle and beta-oxidation pathway in the control of TAG synthesis and lipid accumulation in Yarrowia lipolytica, Metab. Eng., 13, 482, 10.1016/j.ymben.2011.05.002
Farhi, 2011, Harnessing yeast subcellular compartments for the production of plant terpenoids, Metab. Eng., 13, 474, 10.1016/j.ymben.2011.05.001
Fickers, 2003, New disruption cassettes for rapid gene disruption and marker rescue in the yeast Yarrowia lipolytica, J. Microbiol. Methods, 55, 727, 10.1016/j.mimet.2003.07.003
Good, 2011, Scaffold proteins: hubs for controlling the flow of cellular information, Science, 332, 680, 10.1126/science.1198701
Hama, 2018, How lipase technology contributes to evolution of biodiesel production using multiple feedstocks, Curr. Opin. Biotechnol., 50, 57, 10.1016/j.copbio.2017.11.001
Hammer, 2017, Harnessing yeast organelles for metabolic engineering, Nat. Chem. Biol., 13, 823, 10.1038/nchembio.2429
Han, 2013, Tunable nano-oleosomes derived from engineered Yarrowia lipolytica, Biotechnol. Bioeng., 110, 702, 10.1002/bit.24761
Kerfeld, 2010, Bacterial microcompartments, Annu. Rev. Microbiol., 64, 391, 10.1146/annurev.micro.112408.134211
Lee, 2012, Systems metabolic engineering of microorganisms for natural and non-natural chemicals, Nat. Chem. Biol., 8, 536, 10.1038/nchembio.970
Lennen, 2012, Engineering Escherichia coli to synthesize free fatty acids, Trends Biotechnol., 30, 659, 10.1016/j.tibtech.2012.09.006
Li, 2019, A genetically-encoded synthetic self-assembled multienzyme complex of lipase and P450 fatty acid decarboxylase for efficient bioproduction of fatty alkenes, Bioresour. Technol., 272, 451, 10.1016/j.biortech.2018.10.067
Lin, 2017, Synthetic protein scaffolds for biosynthetic pathway colocalization on lipid droplet membranes, ACS Synth. Biol., 6, 1534, 10.1021/acssynbio.7b00041
Liu, 2015, An evolutionary metabolic engineering approach for enhancing lipogenesis in Yarrowia lipolytica, Metab. Eng., 29, 36, 10.1016/j.ymben.2015.02.003
Liu, 2019, Understanding lipogenesis by dynamically profiling transcriptional activity of lipogenic promoters in Yarrowia lipolytica, Appl. Microbiol. Biotechnol., 103, 3167, 10.1007/s00253-019-09664-8
Madzak, 2004, Heterologous protein expression and secretion in the non-conventional yeast Yarrowia lipolytica: a review, J. Biotechnol., 109, 63, 10.1016/j.jbiotec.2003.10.027
Marella, 2017, Engineering microbial fatty acid metabolism for biofuels and biochemicals, Curr. Opin. Biotechnol., 50, 39, 10.1016/j.copbio.2017.10.002
Munro, 1987, A C-terminal signal prevents secretion of luminal ER proteins, Cell, 48, 899, 10.1016/0092-8674(87)90086-9
Nicaud, 2002, Protein expression and secretion in the yeast Yarrowia lipolytica, FEMS Yeast Res., 2, 371
Peralta-Yahya, 2012, Microbial engineering for the production of advanced biofuels, Nature, 488, 320, 10.1038/nature11478
Park, 2017, Systems biology for understanding and engineering of heterotrophic oleaginous microorganisms, Biotechnol. J., 12, 1600104, 10.1002/biot.201600104
Qiao, 2015, Engineering lipid overproduction in the oleaginous yeast Yarrowia lipolytica, Metab. Eng., 29, 56, 10.1016/j.ymben.2015.02.005
Qiao, 2017, Lipid production in Yarrowia lipolytica is maximized by engineering cytosolic redox metabolism, Nat. Biotechnol., 35, 173, 10.1038/nbt.3763
Qiao, 2018, Engineering Yarrowia lipolytica for sustainable production of fatty acid methyl esters using in situ self-cycled glycerol as a carbon source, ACS Sustain. Chem. Eng., 6, 7645, 10.1021/acssuschemeng.8b00492
Sadre, 2019, Cytosolic lipid droplets as engineered organelles for production and accumulation of terpenoid biomaterials in leaves, Nat. Commun., 10, 853, 10.1038/s41467-019-08515-4
Schirmer, 2010, Microbial biosynthesis of alkanes, Science, 329, 559, 10.1126/science.1187936
Silverman, 2016, Functional overexpression and characterization of lipogenesis-related genes in the oleaginous yeast Yarrowia lipolytica, Appl. Microbiol. Biotechnol., 100, 3781, 10.1007/s00253-016-7376-0
Steen, 2010, Microbial production of fatty-acid-derived fuels and chemicals from plant biomass, Nature, 463, 559, 10.1038/nature08721
Tai, 2013, Engineering the push and pull of lipid biosynthesis in oleaginous yeast Yarrowia lipolytica for biofuel production, Metab. Eng., 15, 1, 10.1016/j.ymben.2012.08.007
Valle-Rodríguez, 2014, Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid ethyl esters, an advanced biofuel, by eliminating non-essential fatty acid utilization pathways, Appl. Energy, 115, 226, 10.1016/j.apenergy.2013.10.003
Wagner, 2016, Synthetic biology and molecular genetics in non-conventional yeasts: current tools and future advances, Fungal Genet. Biol., 89, 126, 10.1016/j.fgb.2015.12.001
Xu, 2013, Modular optimization of multi-gene pathways for fatty acids production in E. coli, Nat. Commun., 4, 1409, 10.1038/ncomms2425
Xu, 2016, Engineering Yarrowia lipolytica as a platform for synthesis of drop-in transportation fuels and oleochemicals, Proc. Natl. Acad. Sci. U.S.A., 113, 10848, 10.1073/pnas.1607295113
Xu, 2017, Engineering oxidative stress defense pathways to build a robust lipid production platform in Yarrowia lipolytica, Biotechnol. Bioeng., 114, 1521, 10.1002/bit.26285
Xue, 2013, Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica, Nat. Biotechnol., 31, 734, 10.1038/nbt.2622
Yan, 2018, Engineering Yarrowia lipolytica to simultaneously produce lipase and single cell protein from agroindustrial wastes for feed, Sci. Rep., 8, 758, 10.1038/s41598-018-19238-9
Yan, 2019, Engineering a malic enzyme to enhance lipid accumulation in Chlorella protothecoides and direct production of biodiesel from the microalgal biomass, Biomass Bioenergy, 122, 298, 10.1016/j.biombioe.2019.01.046
Yan, 2015, Assembly of lipase and P450 fatty acid decarboxylase to constitute a novel biosynthetic pathway for production of 1-alkene from renewable triglycerides and oils, Biotechnol. Biofuels, 8, 34, 10.1186/s13068-015-0219-x
Yan, 2017, Harnessing the biodiesel producing microbes: from genetic engineering of lipase to metabolic engineering of fatty acid biosynthetic pathway, Crit. Rev. Biotechnol., 37, 26, 10.3109/07388551.2015.1104531
Yang, 2018, Design of a new multienzyme complex synthesis system based on Yarrowia lipolytica simultaneously secreted and surface displayed fusion proteins for sustainable production of fatty acid-derived hydrocarbons, ACS Sustain. Chem. Eng., 6, 17035, 10.1021/acssuschemeng.8b04401
Zhou, 2016, Harnessing yeast peroxisomes for biosynthesis of fatty-acid-derived biofuels and chemicals with relieved side-pathway competition, J. Am. Chem. Soc., 138, 15368, 10.1021/jacs.6b07394