Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci
Trine Folseraas1,2,3, Espen Melum1,2,3, Philipp Rausch4,5, Brian D. Juran6, Eva Ellinghaus7, Alexey Shiryaev1,2,3, Jon K. Laerdahl8,9, David Ellinghaus7, Christoph Schramm10, Tobias J. Weismüller11,12, Daniel Nils Gotthardt13, Johannes Roksund Hov1,2,3, Ole Petter Clausen3,14, Rinse K. Weersma15, Marcel Janse15, Kirsten Muri Boberg1, Einar Björnsson16, Hanns-Ulrich Marschall16, Isabelle Cleynen17, Philip Rosenstiel7
1Norwegian PSC Research Center, Department of Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway
2Research Institute for Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway
3Faculty of Medicine, University of Oslo, Oslo, Norway
4Institute for Experimental Medicine, Christian-Albrechts-University, Kiel, Germany
5Max-Planck-Institute for Evolutionary Biology, Plön, Germany
6Center for Basic Research in Digestive Diseases, Division of Gastroenterology and Hepatology, Mayo Clinic, College of Medicine, Rochester, Minnesota, United States
7Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany
8Centre for Molecular Biology and Neuroscience (CMBN) and Department of Microbiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
9Bioinformatics Core Facility, Department of Informatics, University of Oslo, Oslo, Norway
101st Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
11Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany
12Integrated Research and Treatment Center-Transplantation (IFB-tx), Hannover Medical School, Hannover, Germany
13Department of Medicine, University Hospital of Heidelberg, Heidelberg, Germany
14Division of Pathology, Oslo University Hospital Rikshospitalet, Oslo, Norway
15Department of Gastroenterology and Hepatology, University Medical Center Groningen and University of Groningen, The Netherlands
16Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy and University Hospital, Gothenburg, Sweden
17Department of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium
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Thông tin xuất bản
Journal of Hepatology
Tập 57
366-375
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