Spatial compartmentalization of signaling imparts source-specific functions on secreted factors

Cell Reports - Tập 42 - Trang 112051 - 2023
Elena Groppa1,2, Paolo Martini3,4, Nima Derakhshan1, Marine Theret1, Morten Ritso1, Lin Wei Tung1, Yu Xin Wang5, Hesham Soliman1,6,7, Mark Stephen Hamer1, Laura Stankiewicz1, Christine Eisner1, Le Nevé Erwan8, Chihkai Chang1, Lin Yi1, Jack H. Yuan1, Sunny Kong1, Curtis Weng1, Josephine Adams1, Lucas Chang1, Anne Peng1
1School of Biomedical Engineering, University of British Columbia, 2222 Health Sciences Mall, Vancouver, BC, Canada
2Borea Therapeutics, Scuola Internazionale Superiore di Studi Avanzati, Via Bonomea 265, Trieste, Italy
3Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy
4Department of Biology, University of Padova, via U. Bassi 58B, Padova, Italy
5Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA
6Faculty of Pharmaceutical Sciences, Minia University, Minia, Egypt
7Aspect Biosystems, 1781 W 75th Avenue, Vancouver, BC, Canada
8Department of Pediatrics, Université Laval, Laval, QC, Canada

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