Beyond molecules: Self-assembly of mesoscopic and macroscopic components

George M. Whitesides1, Mila Boncheva1
1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138

Tóm tắt

Self-assembly is a process in which components, either separate or linked, spontaneously form ordered aggregates. Self-assembly can occur with components having sizes from the molecular to the macroscopic, provided that appropriate conditions are met. Although much of the work in self-assembly has focused on molecular components, many of the most interesting applications of self-assembling processes can be found at larger sizes (nanometers to micrometers). These larger systems also offer a level of control over the characteristics of the components and over the interactions among them that makes fundamental investigations especially tractable.

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Tài liệu tham khảo

G M Whitesides, E E Simanek, C B Gorman NATO Advanced Study Institute on Chemical Synthesis: Gnosis to Prognosis, eds C Chatgilialoglu, V Snieckus (Kluwer, Dordrecht, the Netherlands), pp. 565–588 (1996).

D Philip, J F Stoddart Angew Chem Int Ed Engl 35, 1155–1196 (1996).

J M Lehn, P Ball The New Chemistry, ed N Hall (Cambridge Univ. Press, Cambridge, U.K.), pp. 300–351 (2000).

G R Desiraju Crystal Engineering: The Design of Organic Solids (Elsevier, New York, 1989).

D F Evans, H Wennerstrom The Colloidal Domain: Where Physics, Chemistry, Biology, and Technology Meet (Wiley, New York, 1999).

M N Jones, D Chapman Micelles, Monolayers, and Biomembranes (Wiley–Liss, New York, 1995).

10.1126/science.286.5443.1307

10.1021/ar00053a003

10.1016/S0959-440X(00)00176-7

S Neidle Oxford Handbook of Nucleic Acid Structure (Oxford Univ. Press, Oxford, U.K., 1999).

10.1088/0034-4885/62/6/202

B Alberts, D Bray, J Lewis, M Raff, K Roberts, J D Watson Molecular Biology of the Cell (Garland, New York, 1994).

10.1021/ja952836l

10.1126/science.293.5532.1119

10.1038/35013018

10.1038/scientificamerican1095-146

L Isaacs, D N Chin, N Bowden, Y Xia, G M Whitesides Supramolecular Technology, ed D N Reinhoudt (Wiley, New York), pp. 1–46 (1999).

10.1126/science.290.5499.2123

10.1073/pnas.091588098

10.1126/science.283.5400.372

10.1002/(SICI)1521-4095(200005)12:10<693::AID-ADMA693>3.0.CO;2-J

10.1063/1.1351525

10.1038/scientificamerican0901-58

10.1126/science.290.5490.314

10.1126/science.287.5460.1989

10.1038/19740

J-M Lehn NATO ASI Ser Ser E 320, 511–524 (1996).

10.1002/anie.199012091

10.1038/scientificamerican0901-78

M Madou Fundamentals of Microfabrication (CRC, Boca Raton, FL, 1997).

K F Boehringer, R S Fearing, K Y Goldberg The Handbook of Industrial Robotics, ed S Nof (Wiley, New York), pp. 1045–1066 (1999).

10.1021/ar0000760

10.1126/science.276.5310.233

10.1021/jp993118e

10.1126/science.280.5372.2089

10.1021/ja010634l

10.1006/jcis.1999.6695

10.1021/ja983882z

10.1021/jp0026383

10.1049/el:19930444

10.1016/S0924-4247(99)00220-4

10.1126/science.289.5482.1170

10.1109/68.300169

10.1109/84.911087

10.1162/artl.1994.1.4.413

Boehringer K. F. Srinivasan U. & Howe R. T. (2001) Proc. IEEE Conf. Microelectromech. Syst. 369–374.

10.1146/annurev.biochem.70.1.603

10.1021/la991450b

10.1021/ja981390g

10.1021/la9506786

10.1021/cm00054a028

M Boncheva, D H Gracias, H O Jacobs, G M Whitesides Proc. Natl. Acad. Sci. USA., 2002).

10.1021/ja001874o

10.1021/ja0120633

Clark T. D. Ferrigno R. Tien J. Paul K. & Whitesides G. M. (2002) J. Am. Chem. Soc. in press.

10.1002/1521-4095(200103)13:6<409::AID-ADMA409>3.0.CO;2-C

10.1126/science.1065824

10.1038/35051047

10.1021/nl015606f

10.1038/scientificamerican0600-86

10.1038/23912

10.1038/35099520

10.1126/science.284.5416.948

S A Campbell The Science and Engineering of Microelectronic Fabrication (Oxford Univ. Press, New York, 1996).

10.1007/3-540-69544-3_1

10.1063/1.122621

10.1021/cr980002q

Jacobs H. O. Tao A. R. Schwartz A. Gracias D. H. & Whitesides G. M. (2002) Science in press.

R R A Syms, C Gormley, S Blackstone Sens Actuators A 2839, 1–11 (2000).

10.1002/1521-4095(20020205)14:3<235::AID-ADMA235>3.0.CO;2-B

10.1126/science.290.5496.1540

10.1002/(SICI)1521-4095(199902)11:2<165::AID-ADMA165>3.0.CO;2-3

10.1021/ja011048v

10.1038/414735a

P Ball The Self-Made Tapestry: Pattern Formation in Nature (Oxford Univ. Press, Oxford, U.K., 1999).

10.1038/35016528

10.1021/jp011187z

10.1021/ar00049a006