Long gonadotropin-releasing hormone agonist versus short agonist versus antagonist regimens in poor responders undergoing in vitro fertilization: a randomized controlled trial

Fertility and Sterility - Tập 101 - Trang 147-153 - 2014
Sesh Kamal Sunkara1, Arri Coomarasamy2, Raef Faris3, Peter Braude1, Yacoub Khalaf1
1Assisted Conception Unit, Guy's and St. Thomas' Foundation Trust, King's College London, United Kingdom
2Academic Unit, University of Birmingham, Birmingham Women's Hospital, Birmingham, United Kingdom
3Lister Fertility Clinic, The Lister Hospital London, United Kingdom

Tài liệu tham khảo

Garcia, 1983, Human menopausal gonadotrophin/human chorionic gonadotrophin follicular maturation for oocyte aspiration/phase II, 1981, Fertil Steril, 39, 174, 10.1016/S0015-0282(16)46815-9 Karande, 1999, A rational approach to the management of low responders in in-vitro fertilization, Humanit Rep, 14, 1744, 10.1093/humrep/14.7.1744 Keay, 1997, Assisted conception following poor ovarian response to gonadotrophin stimulation, Br J Obstet Gynecol, 104, 521, 10.1111/j.1471-0528.1997.tb11525.x Bewley, 2005, Which career first?, BMJ, 331, 588, 10.1136/bmj.331.7517.588 Ulug, 2003, Conception rates following assisted reproduction in poor responder patients: a retrospective study in 300 consecutive cycles, Reprod Biomed Online, 6, 439, 10.1016/S1472-6483(10)62164-5 Sunkara, 2011, Association between the number of eggs and live birth in IVF treatment: an analysis of 400,135 treatment cycles, Hum Reprod, 26, 1768, 10.1093/humrep/der106 Shanbhag, 2007, Interventions for “poor responders” to controlled ovarian hyperstimulation (COS) in in-vitro fertilisation (IVF), Cochrane Database Syst Rev, 1, CD004379 Hughes, 1992, The routine use of gonadotropin releasing hormone agonists prior to in-vitro fertilization and gamete intrafallopian transfer: a meta-analysis of randomized controlled trials, Fertil Steril, 58, 888, 10.1016/S0015-0282(16)55430-2 Daya, 2000, Gonadotropin releasing hormone agonist protocols for pituitary desensitization in in vitro fertilization and gamete intrafallopian transfer cycles, Cochrane Database Syst Rev, 2, CD001299 Garcia, 1990, Follicular phase gonadotropin-releasing hormone agonist and human gonadotropins: a better alternative for ovulation induction in in vitro fertilization, Fertil Steril, 53, 302, 10.1016/S0015-0282(16)53285-3 Kenigsberg, 1984, Medical hypophysectomy. I. Dose-response using a gonadotropin-releasing hormone antagonist, Fertil Steril, 42, 112, 10.1016/S0015-0282(16)47968-9 IVF Worldwide Survey. Poor responders: how to define, diagnose and treat? www.IVF-Worldwide.com. Sunkara, 2007, Reprod Health, 4, 12, 10.1186/1742-4755-4-12 Kailasam, 2004, Defining poor ovarian response during IVF cycles, in women aged <40 years, and its relationship with treatment outcome, Hum Reprod, 19, 1544, 10.1093/humrep/deh273 Cheung, 2005, GnRH antagonist versus long GnRH agonist protocol in poor responders undergoing IVF: a randomized controlled trial, Hum Reprod, 20, 616, 10.1093/humrep/deh668 Kucuk, 2008, Efficiency of follicle-stimulating hormone, commenced in the luteal phase, for overcoming a poor response in assisted reproduction, J Obstet Gynaecol Res, 34, 574, 10.1111/j.1447-0756.2008.00750.x Pandian, 2010, Interventions for “poor responders” to controlled ovarian hyper stimulation (COS) in in-vitro fertilisation (IVF), Cochrane Database Systematic Rev, 1, CD004379 Dirnfeld, 1991, A randomized prospective study on the effect of short and long buserelin treatment in women with repeated unsuccessful in vitro fertilization (IVF) cycles due to inadequate ovarian response, J In Vitro Fert Embryo Transf, 8, 339, 10.1007/BF01133025 Weissman, 2003, Prospective evaluation of two stimulation protocols for low responders who were undergoing in vitro fertilization-embryo transfer, Fertil Steril, 79, 886, 10.1016/S0015-0282(02)04928-2 Marci, 2003, A prospective, randomized comparison of two short stimulation protocols with agonist and antagonist of GnRH in poor responders patients undergoing IVF. Preliminary report. Abstracts of the 19th Annual Meeting of the ESHRE, Madrid, Spain, Hum Reprod, 18, 113 Malmusi, 2005, Comparison of a gonadotropin-releasing hormone (GnRH) antagonist and GnRH agonist flare-up regimen in poor responders undergoing ovarian stimulation, Fertil Steril, 84, 402, 10.1016/j.fertnstert.2005.01.139 Schmidt, 2005, A randomized prospective study of microdose leuprolide versus ganirelix in in vitro fertilization cycles for poor responders, Fertil Steril, 83, 1568, 10.1016/j.fertnstert.2004.10.053 Aletebi, 2007, Comparing gonadotrophin-releasing hormone agonists or gonadotrophin-releasing hormone antagonists in poor responder in IVF, Middle East Fertil Soc J, 12, 123 Kahraman, 2009, Microdose gonadotropin-releasing hormone agonist flare-up protocol versus multiple dose gonadotropin-releasing hormone antagonist protocol in poor responders undergoing intracytoplasmic sperm injection-embryo transfer cycle, Fertil Steril, 91, 2437, 10.1016/j.fertnstert.2008.03.057 Lainas, 2008, Flexible GnRH antagonist versus flare-up GnRH agonist protocol in poor responders treated by IVF: a randomized controlled trial, Hum Reprod, 23, 1355, 10.1093/humrep/den107 Marci, 2005, GnRH antagonist in IVF poor-responder patients: results of a randomized trial, Reprod Biomed Online, 11, 189, 10.1016/S1472-6483(10)60957-1 Tazegul, 2008, Comparison of multiple dose GnRH antagonist and minidose long agonist protocols in poor responders undergoing in vitro fertilization: a randomized controlled trial, Arch Gynecol Obstet, 278, 467, 10.1007/s00404-008-0620-9 Tehraninejad, 2009, Flexible, multi-dose GnRH antagonist versus long GnRH agonist protocol in poor responders: a randomized controlled trial, Int J Fertil Steril, 2, 165 Griesinger, 2006, GnRH-antagonists in ovarian stimulation for IVF in patients with poor response to gonadotrophins, polycystic ovary syndrome, and risk of ovarian hyperstimulation: a meta-analysis, Reprod Biomed Online, 13, 628, 10.1016/S1472-6483(10)60652-9 Pu, 2011, Comparison of GnRH antagonist versus GnRH agonist protocol in poor ovarian responders undergoing IVF, Hum Reprod, 26, 2742, 10.1093/humrep/der240 Madani, 2012, Comparison of different stimulation protocols efficacy in poor responders undergoing IVF: a retrospective study, Gynaecol Endocrinol, 28, 102, 10.3109/09513590.2011.579206 van Rooij, 2003, Women older than 40 years of age and those with elevated follicle-stimulating hormone levels differ in poor response rate and embryo quality in in vitro fertilization, Fertil Steril, 79, 482, 10.1016/S0015-0282(02)04839-2 Broekmans, 2006, A systematic review of tests predicting ovarian reserve and IVF outcome, Hum Reprod Update, 12, 685, 10.1093/humupd/dml034 Dor, 1992, The prognostic importance of the number of oocytes retrieved and estradiol levels in poor and normal responders in in vitro fertilization (IVF) treatment, J Assist Reprod Genet, 9, 228, 10.1007/BF01203818 Ferraretti, 2011, ESHRE consensus on the definition of “poor response” to ovarian stimulation for in vitro fertilization: the Bologna criteria, Hum Reprod, 26, 1616, 10.1093/humrep/der092 Sims, 1994, Early follicular rise of serum progesterone concentration in response to flare-up effect of gonadotrophin-releasing hormone agonist impairs follicular recruitment for in-vitro fertilization, Hum Reprod, 9, 235, 10.1093/oxfordjournals.humrep.a138488