Proliferative inhibition of human breast carcinoma cells by high concentration estradiol does not alter radiosensitivity

Lippman M, Bolan G, Huff K: The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture. Cancer Res 36: 4595–4601, 1976

Bezwoda WR, Meyer K: Effect of a-interferon, 17β-estradiol, and tamoxifen on estrogen receptor concentration and cell cycle kinetics of MCF-7 cells. Cancer Res 50: 5387–5391, 1990

Reddel RR, Sutherland RL: Effects of pharmacological concentrations of estrogens on proliferation and cell cycle kinetics of human breast cancer cell linein vitro. Cancer Res 47: 5323–5329, 1987

Adair FE, Mellors RC, Farrow JH, Woodward HQ, Escher GC, Urban JA: The use of oestrogen and androgens in advanced mammary cancer. J Am Med Assoc 140: 1193–1200, 1949

Binnie GG: Regression of tumours following treatment by stilboestrol and X-ray therapy. Br J Radiol 17: 42–45, 1944

Kawada I: Effects of progesterone and estrogens on the multiplications of chick fibroblasts, rat Ascites hepatoma cells, and strain HeLa cells (cervical carcinoma of human uterus) in tissue culture. Jpn J Exp Med 29: 615–626, 1959

Kuchler RJ, Grauer RC: Effects of natural estrogens on L strain fibroblasts in tissue culture. Proc Soc Exp Biol Med 110: 287–292, 1962

McLachlan JA, Wong A, Degen GH, Barrett JC: Morphological changes in human breast fibroblasts by diethylstilbestrol and its analogues. Cancer Res 42: 3040–3045, 1982

Riley PA, Latter A, Sutton PM: Reversible morphological changes in human breast fibroblasts exposed to stilbestrol. Eur J Cancer 14: 579–586, 1978

Tsutsui T, Maizumi H, McLachlan JA, Barrett JC: Aneuploidy induction and cell transformation by diethylstilbestrol: a possible chromosomal mechanism in carcinogenesis. Cancer Res 43: 3814–3821, 1983

Brandes LJ, Hermonat MW: Receptor status and subsequent sensitivity of subclones of MCF-7 human breast cancer cells surviving exposure to diethylstillbestrol. Cancer Res 43: 2831–2835, 1983

Goldenburg GJ, Froese EK: Drug and hormone sensitivity of estrogen receptor-positive and -negative human breast cancer cellsin vitro. Cancer Res 42: 5147–5151, 1982

Rao NP, Engelberg J: Structural specificity of estrogens in the induction of mitotic chromatid non-disjunction in HeLa cells. Exp Cell Res 48: 71–81, 1967

Rao NP: Estradiol-induced mitotic delay in HeLa cells: Reversal by calcium chloride and putrescine. Exp Cell Res 57: 230–234, 1969

Weichselbaum RR, Hellman S, Piro AJ, Nove JT, Little JB: Proliferation kinetics of a human breast cancer cell linein vitro following treatment with 17β-estradiol and 1-B-D-arabinofuranosylcytosine. Cancer Res 38: 2339–2342, 1978

Osborne CK, Boldt DH, Clark GM, Trent JM: Effects of tamoxifen on human breast cancer cell cycle kinetics: Accumulation of cells in early G1 phase. Cancer Res 43: 3583–3585, 1983

Sutherland RL, Green MD, Hall RE, Reddel RR, Taylor IW: Tamoxifen induces accumulation of MCF-7 human mammary carcinoma cells in the G0/G1 phase of the cell cycle. Eur J Cancer Clin Oncol 19: 615–621, 1983

Hug V, Hortobagyi GN, Drewinko B, Finders M: Tamoxifen-citrate counteracts the antitumor effects of cytotoxic drugsin vitro. J Clin Oncol 3: 1672–1677, 1985

Osborne CK, Kitten L, Arteaga CL: Antagonism of chemotherapy-induced cytotoxicity for human breast cancer cells by antiestrogens. J Clin Oncol 7: 710–717, 1989

Wazer DE, Tercilla OF, Lin P-S, Schmidt-Ullrich R: Modulation in the radiosensitivity of MCF-7 human breast carcinoma cells by 17β-estradiol and tamoxifen. Brit J Radiology 62: 1079–1083, 1989

Taylor IW: A rapid single step staining technique for DNA analysis by flow microfluorimetry. J Histochem Cytochem 28: 1021–1024, 1980

Olive PL: DNA precipitation assay: A rapid and simple method for detecting DNA damage in mammalian cells. Environ Molec Mutagenesis 11: 487–495, 1988

Armitage P, Berry G: Statistical Methods in Medical Research. Blackwell Scientific Publications, Boston, 1988, pp 98–100

McGuire WL, Carbone PP, Sears ME, Escher GC: Estrogen receptors in human breast cancer. Raven Press, New York, 1975, pp 1–8

Sinclair W, Morton R: X-ray sensitivity during the cell generation cycle of cultured Chinese hamster cells. Rad Res 29: 450–474, 1966

Wheeler KT, Nelson GB, Terrell KE, Wallen CA: Regulation of DNA repair kinetics in proliferative and quiescent tumor cells. Int J Radiat Biol 54: 245–255, 1988

Sweigert SE, Rowley R, Warters RL, Dethlefsen LA: Cell cycle effect on the induction of DNA double-strand breaks by X-rays. Rad Res 116: 228–244, 1988

Hall EJ: Radiobiology for the Radiobiologist. Harper and Row, New York, 1978, pp 24–28

Kellerer AM, Hug O: Theory of dose-effect relations. In: Encyclopedia of Medical Radiology. Springer Verlag, Berlin, 1972, pp 1–42

Fertil B, Dertinger H, Courdi A, Malaise EP: Mean inactivation dose: A useful concept for intercomparison of human cell survival curves. Rad Res 99: 73–94, 1984