Lipid engineering combined with systematic metabolic engineering of Saccharomyces cerevisiae for high-yield production of lycopene

Metabolic Engineering - Tập 52 - Trang 134-142 - 2019
Tian Ma1, Bin Shi1, Ziling Ye2, Xiaowei Li1, Min Liu1, Yun Chen3, Jiang Xia4, Jens Nielsen3,5,6, Zixin Deng1,7, Tiangang Liu1,8
1Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education and School of Pharmaceutical Sciences, Wuhan University, Wuhan 430072, China
2J1 Biotech Co., Ltd., Wuhan 430075, PR China
3Department of Biology and Biological Engineering, Chalmers University of Technology, SE412 96 Gothenburg, Sweden
4Department of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
5Novo Nordisk Foundation Center for Biosustainability, Chalmers University of Technology, SE412 96 Gothenburg, Sweden
6Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, DK2800 Kongens Lyngby, Denmark
7State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, China
8Hubei Engineering Laboratory for Synthetic Microbiology, Wuhan Institute of Biotechnology, Wuhan, 430075, China

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