Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface

Journal of Lipid Research - Tập 40 Số 3 - Trang 575-580 - 1999
Margarita de la Llera-Moya1, George H. Rothblat1, Margery A. Connelly2, Ginny Kellner-Weibel1, Sana Sakr1, Michael C. Phillips1, David L. Williams2
1Department of Biochemistry, MCP ♦ Hahnemann School of Medicine, Philadelphia PA, 19129
2Department of Pharmacological Sciences, SUNY at Stony Brook, University Medical Center, Stony Brook, NY 11794

Tóm tắt

Từ khóa


Tài liệu tham khảo

Brown, 1986, A receptor-mediated pathway for cholesterol homeostasis, Science., 232, 34, 10.1126/science.3513311

Acton, 1996, Identification of scavenger receptor SR-BI as a high density lipoprotein receptor, Science., 271, 518, 10.1126/science.271.5248.518

Temel, 1997, Scavenger receptor class B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells, Proc. Natl. Acad. Sci. USA., 94, 13600, 10.1073/pnas.94.25.13600

Rigotti, 1997, A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class class B type I reveals its key role in HDL metabolism, Proc. Natl. Acad. Sci. USA., 94, 12610, 10.1073/pnas.94.23.12610

Ji, 1997, Scavenger receptor B1 promotes high density lipoprotein-mediated cellular cholesterol efflux, J. Biol. Chem., 272, 20982, 10.1074/jbc.272.34.20982

Jian, 1998, Scavenger receptor class B type I as a mediator of cellular cholesterol efflux to lipoproteins and phospholipid acceptors, J. Biol. Chem., 273, 5599, 10.1074/jbc.273.10.5599

Calvo, 1998, Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL, J. Lipid Res., 39, 777, 10.1016/S0022-2275(20)32566-9

Gu, 1998, The efficient cellular uptake of high density lipoprotein lipids via scavenger receptor class B type I requires not only receptor-mediated surface binding but also receptor-specific lipid transfer mediated by its extracellular domain, J. Biol. Chem., 273, 26338, 10.1074/jbc.273.41.26338

Connelly, 1999, Comparison of class B scavenger receptors, CD36 and scavenger receptor BI (SR-BI), show that both receptors mediate high density lipoprotein cholesteryl ester selective uptake but SR-BI exhibits a unique enhancement of cholesteryl ester uptake, J. Biol. Chem., 274, 41, 10.1074/jbc.274.1.41

Hatch, 1968, Practical methods for plasma lipoprotein analysis, Adv. Lipid Res., 6, 1, 10.1016/B978-1-4831-9942-9.50008-5

Gillotte, 1996, Apolipoprotein A-I structural modification and functionality of reconstituted high density lipoprotein particles in cellular cholesterol efflux, J. Biol. Chem., 271, 23792, 10.1074/jbc.271.39.23792

Fukasawa, 1996, SR-BI, a class B scavenger receptor, recognizes both negatively charged liposomes and apoptotic cells, Exp. Cell Res., 222, 246, 10.1006/excr.1996.0030

Ibrahimi, 1996, Expression of the CD36 homolog (FAT) in fibroblast cells: effects on fatty acid transport, Proc. Natl. Acad. Sci. USA., 93, 2646, 10.1073/pnas.93.7.2646

de la Llera-Moya, 1994, A cell culture system for screening human serum for ability to promote cellular cholesterol efflux: relationships between serum components and efflux, esterification and transfer, Arterioscler. Thromb., 14, 1056, 10.1161/01.ATV.14.7.1056

Ross, 1984, Selective inhibition of acylCoA:cholesterol acyltransferase by compound 58-035, J. Biol. Chem., 258, 815, 10.1016/S0021-9258(17)43530-7

Bilheimer, 1972, The metabolism of very low density lipoprotein proteins. I. Preliminary in vitro and in vivo observations, Biochim. Biophys. Acta., 260, 212, 10.1016/0005-2760(72)90034-3

Slotte, 1988, Depletion of plasma-membrane sphingomyelin rapidly alters the distribution of cholesterol between plasma membranes and intracellular cholesterol pools in cultured fibroblasts, Biochem. J., 250, 653, 10.1042/bj2500653

Johnson, 1986, The bidirectional flux of cholesterol between cells and lipoproteins, J. Biol. Chem., 261, 5766, 10.1016/S0021-9258(17)38448-X

Rigotti, 1995, The class B scavenger receptors SR-BI and CD36 are receptors for anionic phospholipids, J. Biol. Chem., 270, 16221, 10.1074/jbc.270.27.16221

Acton, 1994, Expression cloning of SR-B1, a CD36-related class B scavenger receptor, J. Biol. Chem., 269, 21003, 10.1016/S0021-9258(17)31921-X

Akira, 1993, Cholesterol is poorly available for free apolipoprotein-mediated cellular lipid efflux from smooth muscle cells, Biochemistry., 32, 4597, 10.1021/bi00068a016

Forte, 1995, Recruitment of cell phospholipids and cholesterol by apolipoproteins A-II and A-I: formation of nascent apolipoprotein-specific HDL that differ in size, phospholipid composition, and reactivity with LCAT, J. Lipid Res., 36, 148, 10.1016/S0022-2275(20)39763-7

Bielicki, 1992, Efflux of lipid from fibroblasts to apolipoproteins: dependence on elevated levels of cellular unesterified cholesterol, J. Lipid Res., 33, 1699, 10.1016/S0022-2275(20)41392-6

Yancey, 1995, The efflux of cellular cholesterol and phospholipid to lipid-free apolipoproteins and class A amphipathic peptides, Biochemistry., 34, 7955, 10.1021/bi00024a021

Jacobs, 1997, Analysis of a Chinese hamster ovary cell mutant with defective mobilization of cholesterol from the plasma membrane to the endoplasmic reticulum, J. Lipid Res., 38, 1973, 10.1016/S0022-2275(20)37128-5

Jian, 1997, Modification of the cholesterol efflux properties of human serum by enrichment with phospholipid, J. Lipid Res., 38, 152, 10.1016/S0022-2275(20)37240-0

Babitt, 1997, Murine SR-B1, a high density lipoprotein receptor that mediates selective lipid uptake, is N-glycosylated and fatty acylated and colocalizes with plasma membrane caveolae, J. Biol. Chem., 272, 13242, 10.1074/jbc.272.20.13242