Total knee replacement and non-surgical treatment of knee osteoarthritis: 2-year outcome from two parallel randomized controlled trials

Cross, 2014, The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study, Ann Rheum Dis, 73, 1323, 10.1136/annrheumdis-2013-204763 Deshpande, 2016, Number of persons with symptomatic knee osteoarthritis in the US: impact of race and ethnicity, age, sex, and obesity, Arthritis Care Res, 68, 1743, 10.1002/acr.22897 St Sauver, 2013, Why patients visit their doctors: assessing the most prevalent conditions in a defined American population, Mayo Clin Proc, 88, 56, 10.1016/j.mayocp.2012.08.020 Nguyen, 2011, Increasing prevalence of knee pain and symptomatic knee osteoarthritis: survey and cohort data, Ann Intern Med, 155, 725, 10.7326/0003-4819-155-11-201112060-00004 March, 1997, Economics of osteoarthritis: a global perspective, Baillieres Clin Rheumatol, 11, 817, 10.1016/S0950-3579(97)80011-8 Nelson, 2014, A systematic review of recommendations and guidelines for the management of osteoarthritis: the chronic osteoarthritis management initiative of the U.S. bone and joint initiative, Semin Arthritis Rheum, 43, 701, 10.1016/j.semarthrit.2013.11.012 McAlindon, 2014, OARSI guidelines for the non-surgical management of knee osteoarthritis, Osteoarthritis Cartilage, 22, 363, 10.1016/j.joca.2014.01.003 Fernandes, 2013, EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis, Ann Rheum Dis, 72, 1125, 10.1136/annrheumdis-2012-202745 Carr, 2012, Knee replacement, Lancet, 379, 1331, 10.1016/S0140-6736(11)60752-6 Beswick, 2012, What proportion of patients report long-term pain after total hip or knee replacement for osteoarthritis? A systematic review of prospective studies in unselected patients, BMJ Open, 2, e000435, 10.1136/bmjopen-2011-000435 Singh, 2010, A population-based study of trends in the use of total hip and total knee arthroplasty, 1969–2008, Mayo Clin Proc, 85, 898, 10.4065/mcp.2010.0115 Skou, 2015, A randomized, controlled trial of total knee replacement, N Engl J Med, 373, 1597, 10.1056/NEJMoa1505467 Skou, 2015, The efficacy of 12 weeks non-surgical treatment for patients not eligible for total knee replacement: a randomized controlled trial with 1-year follow-up, Osteoarthritis Cartilage, 23, 1465, 10.1016/j.joca.2015.04.021 Skou, 2012, Total knee replacement plus physical and medical therapy or treatment with physical and medical therapy alone: a randomised controlled trial in patients with knee osteoarthritis (the MEDIC-study), BMC Musculoskelet Disord, 13, 67, 10.1186/1471-2474-13-67 Skou, 2012, Efficacy of multimodal, systematic non-surgical treatment of knee osteoarthritis for patients not eligible for a total knee replacement: a study protocol of a randomised controlled trial, BMJ Open, 2, 10.1136/bmjopen-2012-002168 Skou, 2016, Criteria used when deciding on eligibility for total knee arthroplasty – between thinking and doing, Knee, 23, 6, 10.1016/j.knee.2015.08.012 Moher, 2010, CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials, BMJ, 340, c869, 10.1136/bmj.c869 Schiphof, 2011, Impact of different descriptions of the Kellgren and Lawrence classification criteria on the diagnosis of knee osteoarthritis, Ann Rheum Dis, 70, 1422, 10.1136/ard.2010.147520 Collins, 2016, Knee Injury and Osteoarthritis Outcome Score (KOOS): systematic review and meta-analysis of measurement properties, Osteoarthritis Cartilage, 24, 1317, 10.1016/j.joca.2016.03.010 Endres, 2011, High-flexion versus conventional total knee arthroplasty: a 5-year study, J Orthop Surg, 19, 226 Ageberg, 2010, Feasibility of neuromuscular training in patients with severe hip or knee OA: the individualized goal-based NEMEX-TJR training program, BMC Musculoskelet Disord, 11, 126, 10.1186/1471-2474-11-126 Christensen, 2007, Effect of weight reduction in obese patients diagnosed with knee osteoarthritis: a systematic review and meta-analysis, Ann Rheum Dis, 66, 433, 10.1136/ard.2006.065904 Miller, 2002 Ageberg, 2010, Validity and inter-rater reliability of medio-lateral knee motion observed during a single-limb mini squat, BMC Musculoskelet Disord, 11, 265, 10.1186/1471-2474-11-265 Roos, 1998, Knee Injury and Osteoarthritis Outcome Score (KOOS)–development of a self-administered outcome measure, J Orthop Sports Phys Ther, 28, 88, 10.2519/jospt.1998.28.2.88 Roos, 2003, Knee injury and Osteoarthritis Outcome Score (KOOS) – validation and comparison to the WOMAC in total knee replacement, Health Qual Life Outcomes, 1, 17, 10.1186/1477-7525-1-17 Roos, 2011, ICRS recommendation document: patient-reported outcome instruments for use in patients with articular cartilage defects, Cartilage, 2, 122, 10.1177/1947603510391084 Podsiadlo, 1991, The timed “Up & Go”: a test of basic functional mobility for frail elderly persons, J Am Geriatr Soc, 39, 142, 10.1111/j.1532-5415.1991.tb01616.x White, 2010, Do worsening knee radiographs mean greater chances of severe functional limitation?, Arthritis Care Res, 62, 1433, 10.1002/acr.20247 Skou, 2014 Skou, 2014 Zou, 2004, A modified Poisson regression approach to prospective studies with binary data, Am J Epidemiol, 159, 702, 10.1093/aje/kwh090 Hurley, 2012, Long-term outcomes and costs of an integrated rehabilitation program for chronic knee pain: a pragmatic, cluster randomized, controlled trial, Arthritis Care Res, 64, 238, 10.1002/acr.20642 Villadsen, 2014, Immediate efficacy of neuromuscular exercise in patients with severe osteoarthritis of the hip or knee: a secondary analysis from a randomized controlled trial, J Rheumatol, 41, 1385, 10.3899/jrheum.130642 Osiri, 2003, Number needed to treat (NNT): implication in rheumatology clinical practice, Ann Rheum Dis, 62, 316, 10.1136/ard.62.4.316 Altman, 1998, Confidence intervals for the number needed to treat, BMJ, 317, 1309, 10.1136/bmj.317.7168.1309 Ackerman, 2009, Variation in age and physical status prior to total knee and hip replacement surgery: a comparison of centers in Australia and Europe, Arthritis Rheum, 61, 166, 10.1002/art.24215 Gossec, 2011, The role of pain and functional impairment in the decision to recommend total joint replacement in hip and knee osteoarthritis: an international cross-sectional study of 1909 patients. Report of the OARSI-OMERACT Task Force on total joint replacement, Osteoarthritis Cartilage, 19, 147, 10.1016/j.joca.2010.10.025 Mandl, 2013, Determining who should be referred for total hip and knee replacements, Nat Rev Rheumatol, 9, 351, 10.1038/nrrheum.2013.27 Wright, 2011, Variability in physician opinions about the indications for knee arthroplasty, J Arthroplasty, 26 Troelsen, 2012, Opinions among Danish knee surgeons about indications to perform total knee replacement showed considerable variation, Dan Med J, 59, A4490 King, 2011, A point of minimal important difference (MID): a critique of terminology and methods, Expert Rev Pharmacoecon Outcomes Res, 11, 171, 10.1586/erp.11.9 Mills, 2016, Examining the minimal important difference of patient-reported outcome measures for individuals with knee osteoarthritis: a model using the knee injury and osteoarthritis outcome score, J Rheumatol, 43, 395, 10.3899/jrheum.150398 Messier, 2013, Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial, J Am Med Assoc, 310, 1263, 10.1001/jama.2013.277669 Messier, 2004, Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the arthritis, diet, and activity promotion trial, Arthritis Rheum, 50, 1501, 10.1002/art.20256 Kadam, 2004, Clinical comorbidity in patients with osteoarthritis: a case-control study of general practice consulters in England and Wales, Ann Rheum Dis, 63, 408, 10.1136/ard.2003.007526 Wesseling, 2013, Impact of self-reported comorbidity on physical and mental health status in early symptomatic osteoarthritis: the CHECK (Cohort Hip and Cohort Knee) study, Rheumatology, 52, 180, 10.1093/rheumatology/kes288 Roos, 2012, Osteoarthritis 2012 year in review: rehabilitation and outcomes, Osteoarthritis Cartilage, 20, 1477, 10.1016/j.joca.2012.08.028 Keurentjes, 2013, Patients with severe radiographic osteoarthritis have a better prognosis in physical functioning after hip and knee replacement: a cohort-study, PLoS One, 8, e59500, 10.1371/journal.pone.0059500 Wise, 2015, Functional impairment is a risk factor for knee replacement in the Multicenter Osteoarthritis Study, Clin Orthop Relat Res, 473, 2505, 10.1007/s11999-015-4211-3 Terwee, 2006, Self-reported physical functioning was more influenced by pain than performance-based physical functioning in knee-osteoarthritis patients, J Clin Epidemiol, 59, 724, 10.1016/j.jclinepi.2005.11.019 Escobar, 2007, Effect of patient characteristics on reported outcomes after total knee replacement, Rheumatology, 46, 112, 10.1093/rheumatology/kel184 Zou, 2016, Examination of overall treatment effect and the proportion attributable to contextual effect in osteoarthritis: meta-analysis of randomised controlled trials, Ann Rheum Dis, 75, 1964, 10.1136/annrheumdis-2015-208387 Bannuru, 2015, Effectiveness and implications of alternative placebo treatments: a systematic review and network meta-analysis of osteoarthritis trials, Ann Intern Med, 163, 365, 10.7326/M15-0623 Kaptchuk, 2000, Do medical devices have enhanced placebo effects?, J Clin Epidemiol, 53, 786, 10.1016/S0895-4356(00)00206-7