Chronic loss of ovarian function decreases transport of leptin into mouse brain

Banks, 2000, Partial saturation and regional variation in the transport of leptin across the blood-brain barrier in normal weight mice, Am. J. Physiol., E1158 Banks, 1999, Impaired transport of leptin across the blood-brain barrier in obesity, Peptides, 20, 1341, 10.1016/S0196-9781(99)00139-4 Banks, 1996, Leptin enters the brain by a saturable system independent of insulin, Peptides, 17, 305, 10.1016/0196-9781(96)00025-3 Bartness, 1984, Effects of interscapular brown adipose tissue denervation on body weight and energy metabolism in ovariectomized and estradiol-treated rats, Behav. Neurosci., 98, 674, 10.1037/0735-7044.98.4.674 Cento, 1999, Leptin levels in menopause: effect of estrogen replacement therapy, Horm. Res., 52, 269, 10.1159/000023493 Forsberg, 2000, Neonatal estrogen treatment and its consequences for thymus development, serum level of autoantibodies to cardiolipin, and the delayed-type hypersensitivity response, J. Toxicol. Environ. Health, 60, 185, 10.1080/009841000156484 Gower, 2000, Leptin in postmenopausal women: influence of hormone therapy, insulin, and fat distribution, J. Clin. Endocrinol. Metab., 85, 1770, 10.1210/jc.85.5.1770 Hadji, 2000, The influence of menopause and body mass index on serum leptin concentrations, Eur. J. Endocrinol., 143, 55, 10.1530/eje.0.1430055 Halaas, 1997, Physiological response to long-term peripheral and central leptin infusion in lean and obese mice, Proc. Natl. Acad. Sci. USA, 94, 8878, 10.1073/pnas.94.16.8878 Hassmen, 1989, Estrogen/gestagen therapy changes soft tissue body composition in postmenopausal women, Metabolism, 38, 662, 10.1016/0026-0495(89)90104-2 Kastin, 2000, Fasting, but not adrenalectomy, reduces transport of leptin into the brain, Peptides, 21, 679, 10.1016/S0196-9781(00)00195-9 Kastin, 1999, Decreased transport of leptin across the blood-brain barrier in rats lacking the short form of the leptin receptor, Peptides, 20, 1449, 10.1016/S0196-9781(99)00156-4 Kotani, 1994, Sexual dimorphism of age-related changes in whole-body fat distribution in the obese, Int. J. Obesity, 18, 207 Leshner, 1973, The effects of gonadectomy on the sex differences in dietary self-selection patterns and carcass compositions of rats, Physiol. Behav., 11, 671, 10.1016/0031-9384(73)90253-9 Maness, 2000, Persistence of blood-to-brain transport of leptin in obese leptin-deficient and leptin receptor-deficient mice, Brain Res., 873, 165, 10.1016/S0006-8993(00)02520-8 McElroy, 1987, Short- and Long-term effects of ovariectomy on food intake, body weight, carcass composition, and brown adipose tissue in rats, Physiol. Behav., 39, 361, 10.1016/0031-9384(87)90235-6 Pan, 2001, Diurnal variation of leptin entry from blood to brain involving partial saturation of the transport system, Life Sci., 68, 2705, 10.1016/S0024-3205(01)01085-2 Poehlman, 1995, Changes in energy balance and body composition at menopause: a controlled longitudinal study, Ann. Intern. Med., 123, 673, 10.7326/0003-4819-123-9-199511010-00005 Shimizu, 1997, Estrogen increases in vivo leptin production in rats and human subjects, J. Endocrinol., 154, 285, 10.1677/joe.0.1540285 Shimomura, 1990, The significance of decreased ambulatory activity during the generation by long-term observation of obesity in ovariectomized rats, Physiol. Behav., 47, 155, 10.1016/0031-9384(90)90055-9 Van Heek, 1997, Diet-induced obese mice develop peripheral, but not central, resistance to leptin, J. Clin. Invest., 99, 385, 10.1172/JCI119171