Adachi-Yamada, 1999, Distortion of proximodistal information causes JNK-dependent apoptosis in Drosophila wing, Nature, 400, 166, 10.1038/22112
Adachi-Yamada, 1999, De novo synthesis of sphingolipids is required for cell survival by down-regulating c-Jun N-terminal kinase in Drosophila imaginal discs, Mol. Cell. Biol., 19, 7276, 10.1128/MCB.19.10.7276
Aggarwal, 2006, Inflammation and cancer: how hot is the link?, Biochem. Pharmacol., 72, 1605, 10.1016/j.bcp.2006.06.029
Agnes, 1999, The Drosophila JNK pathway controls the morphogenesis of imaginal discs during metamorphosis, Development, 126, 5453, 10.1242/dev.126.23.5453
Agrawal, 1995, Neoplastic transformation and aberrant cell-cell interactions in genetic mosaics of lethal(2)giant larvae (lgl), a tumor suppressor gene of Drosophila, Dev. Biol., 172, 218, 10.1006/dbio.1995.0017
Awasaki, 2004, Engulfing action of glial cells is required for programmed axon pruning during Drosophila metamorphosis, Curr. Biol., 14, 668, 10.1016/j.cub.2004.04.001
Bianco, 2007, Two distinct modes of guidance signalling during collective migration of border cells, Nature, 448, 362, 10.1038/nature05965
Bilder, 2004, Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors, Genes Dev., 18, 1909, 10.1101/gad.1211604
Bilder, 2000, Localization of apical epithelial determinants by the basolateral PDZ protein Scribble, Nature, 403, 676, 10.1038/35001108
Bissell, 2001, Putting tumours in context, Nat. Rev. Cancer, 1, 46, 10.1038/35094059
Brouwer, 1984, Serum-dependent “cannibalism” and autodestruction in cultures of human small cell carcinoma of the lung, Cancer Res., 44, 2947
Brugnera, 2002, Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex, Nat. Cell Biol., 4, 574, 10.1038/ncb824
Brumby, 2003, scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila, EMBO J., 22, 5769, 10.1093/emboj/cdg548
Chang, 2001, Mammalian MAP kinase signalling cascades, Nature, 410, 37, 10.1038/35065000
Cho, 2002, Developmental control of blood cell migration by the Drosophila VEGF pathway, Cell, 108, 865, 10.1016/S0092-8674(02)00676-1
Cordero, 2010, Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter, Dev. Cell, 18, 999, 10.1016/j.devcel.2010.05.014
Davis, 2000, Signal transduction by the JNK group of MAP kinases, Cell, 103, 239, 10.1016/S0092-8674(00)00116-1
Duchek, 2001, Guidance of cell migration by the Drosophila PDGF/VEGF receptor, Cell, 107, 17, 10.1016/S0092-8674(01)00502-5
Dunn, 2002, Cancer immunoediting: from immunosurveillance to tumor escape, Nat. Immunol., 3, 991, 10.1038/ni1102-991
Fialkow, 1976, Clonal origin of human tumors, Biochim. Biophys. Acta, 458, 283
Fish, 1994, Alterations in epithelial polarity and the pathogenesis of disease states, N. Engl. J. Med., 330, 1580, 10.1056/NEJM199406023302207
Gardiol, 2006, Human discs large and scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression, Int. J. Cancer, 119, 1285, 10.1002/ijc.21982
Genova, 2000, Functional analysis of Cdc42 in actin filament assembly, epithelial morphogenesis, and cell signaling during Drosophila development, Dev. Biol., 221, 181, 10.1006/dbio.2000.9671
Hanahan, 2000, The hallmarks of cancer, Cell, 100, 57, 10.1016/S0092-8674(00)81683-9
Hariharan, 2006, Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila, Annu. Rev. Genet., 40, 335, 10.1146/annurev.genet.39.073003.100738
Herz, 2006, vps25 mosaics display non-autonomous cell survival and overgrowth, and autonomous apoptosis, Development, 133, 1871, 10.1242/dev.02356
Hoeppner, 2001, Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans, Nature, 412, 202, 10.1038/35084103
Hogan, 2009, Characterization of the interface between normal and transformed epithelial cells, Nat. Cell Biol., 11, 460, 10.1038/ncb1853
Igaki, 2009, Correcting developmental errors by apoptosis: lessons from Drosophila JNK signaling, Apoptosis, 14, 1021, 10.1007/s10495-009-0361-7
Igaki, 2002, Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway, EMBO J., 21, 3009, 10.1093/emboj/cdf306
Igaki, 2006, Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila, Curr. Biol., 16, 1139, 10.1016/j.cub.2006.04.042
Igaki, 2009, Intrinsic tumor suppression and epithelial maintenance by endocytic activation of Eiger/TNF signaling in Drosophila, Dev. Cell, 16, 458, 10.1016/j.devcel.2009.01.002
Ishimaru, 2004, PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis, EMBO J., 23, 3984, 10.1038/sj.emboj.7600417
Kanda, 2004, Regulatory roles of JNK in programmed cell death, J. Biochem., 136, 1, 10.1093/jb/mvh098
Kinzler, 1996, Lessons from hereditary colorectal cancer, Cell, 87, 159, 10.1016/S0092-8674(00)81333-1
Kurant, 2008, Six-microns-under acts upstream of Draper in the glial phagocytosis of apoptotic neurons, Cell, 133, 498, 10.1016/j.cell.2008.02.052
Land, 1983, Cellular oncogenes and multistep carcinogenesis, Science, 222, 771, 10.1126/science.6356358
Lee, 1999, Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis, Neuron, 22, 451, 10.1016/S0896-6273(00)80701-1
Lee, 2001, Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development, Trends Neurosci., 24, 251, 10.1016/S0166-2236(00)01791-4
Li, 2007, Engulfment is required for cell competition, Cell, 129, 1215, 10.1016/j.cell.2007.03.054
Lowe, 2004, Intrinsic tumour suppression, Nature, 432, 307, 10.1038/nature03098
Martin-Blanco, 1998, puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila, Genes Dev., 12, 557, 10.1101/gad.12.4.557
Martin-Blanco, 2000, JNK and decapentaplegic signaling control adhesiveness and cytoskeleton dynamics during thorax closure in Drosophila, Proc. Natl. Acad. Sci. USA, 97, 7888, 10.1073/pnas.97.14.7888
Massimi, 2004, HPV E6 specifically targets different cellular pools of its PDZ domain-containing tumour suppressor substrates for proteasome-mediated degradation, Oncogene, 23, 8033, 10.1038/sj.onc.1207977
Moberg, 2005, Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth, Dev. Cell, 9, 699, 10.1016/j.devcel.2005.09.018
Müller, 1996, armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila, J. Cell Biol., 134, 149, 10.1083/jcb.134.1.149
Nakagawa, 2004, Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix, Br. J. Cancer, 90, 194, 10.1038/sj.bjc.6601465
Navarro, 2005, Junctional recruitment of mammalian Scribble relies on E-cadherin engagement, Oncogene, 24, 4330, 10.1038/sj.onc.1208632
Nolan, 1998, Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes, Genes Dev., 12, 3337, 10.1101/gad.12.21.3337
Nowell, 1976, The clonal evolution of tumor cell populations, Science, 194, 23, 10.1126/science.959840
Overholtzer, 2007, A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion, Cell, 131, 966, 10.1016/j.cell.2007.10.040
Pagliarini, 2003, A genetic screen in Drosophila for metastatic behavior, Science, 302, 1227, 10.1126/science.1088474
Reddien, 2001, Phagocytosis promotes programmed cell death in C. elegans, Nature, 412, 198, 10.1038/35084096
Rhiner, 2010, Flower forms an extracellular code that reveals the fitness of a cell to its neighbors in Drosophila, Dev. Cell, 18, 985, 10.1016/j.devcel.2010.05.010
Rosin, 2004, Apical accumulation of the Drosophila PDGF/VEGF receptor ligands provides a mechanism for triggering localized actin polymerization, Development, 131, 1939, 10.1242/dev.01101
Rushton, 1995, Mutations in a novel gene, myoblast city, provide evidence in support of the founder cell hypothesis for Drosophila muscle development, Development, 121, 1979, 10.1242/dev.121.7.1979
Shankaran, 2001, IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity, Nature, 410, 1107, 10.1038/35074122
Smyth, 2000, Differential tumor surveillance by natural killer (NK) and NKT cells, J. Exp. Med., 191, 661, 10.1084/jem.191.4.661
Stronach, 2005, Dissecting JNK signaling, one KKKinase at a time, Dev. Dyn., 232, 575, 10.1002/dvdy.20283
Szlosarek, 2006, Tumour necrosis factor-alpha as a tumour promoter, Eur. J. Cancer, 42, 745, 10.1016/j.ejca.2006.01.012
Tapon, 2002, salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines, Cell, 110, 467, 10.1016/S0092-8674(02)00824-3
Tepass, 1996, shotgun encodes Drosophila E-cadherin and is preferentially required during cell rearrangement in the neurectoderm and other morphogenetically active epithelia, Genes Dev., 10, 672, 10.1101/gad.10.6.672
Tepass, 2001, Epithelial cell polarity and cell junctions in Drosophila, Annu. Rev. Genet., 35, 747, 10.1146/annurev.genet.35.102401.091415
Thompson, 2005, Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila, Dev. Cell, 9, 711, 10.1016/j.devcel.2005.09.020
Uemura, 1996, Zygotic Drosophila E-cadherin expression is required for processes of dynamic epithelial cell rearrangement in the Drosophila embryo, Genes Dev., 10, 659, 10.1101/gad.10.6.659
Uhlirova, 2005, Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model, Proc. Natl. Acad. Sci. USA, 102, 13123, 10.1073/pnas.0504170102
Vaccari, 2005, The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking, Dev. Cell, 9, 687, 10.1016/j.devcel.2005.09.019
Williams, 2006, Local caspase activity directs engulfment of dendrites during pruning, Nat. Neurosci., 9, 1234, 10.1038/nn1774
Woods, 1991, The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions, Cell, 66, 451, 10.1016/0092-8674(81)90009-X
Wu, 1993, Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression, Cancer Res., 53, 1939
Wu, 2010, Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion, Nature, 463, 545, 10.1038/nature08702
Xia, 2004, The control of cell motility and epithelial morphogenesis by Jun kinases, Trends Cell Biol., 14, 94, 10.1016/j.tcb.2003.12.005
Xu, 1993, Analysis of genetic mosaics in developing and adult Drosophila tissues, Development, 117, 1223, 10.1242/dev.117.4.1223
Xu, 1995, Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase, Development, 121, 1053, 10.1242/dev.121.4.1053
Xue, 2007, Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila, Dev. Cell, 13, 446, 10.1016/j.devcel.2007.07.012
Zhan, 2008, Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma, Cell, 135, 865, 10.1016/j.cell.2008.09.045